LOCUS BC060782 3213 bp mRNA linear HUM 21-JUL-2005
DEFINITION Homo sapiens leucine rich repeat containing 8 family, member B,
mRNA (cDNA clone MGC:71558 IMAGE:5298560), complete cds.
ACCESSION BC060782
VERSION BC060782.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3213)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3213)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (03-NOV-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Miklos Palkovits, M.D., Ph.D.
cDNA Library Preparation: Michael J. Brownstein (NHGRI) & Shiraki
Toshiyuki and Piero Carninci (RIKEN)
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 133 Row: p Column: 22
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 21245133.
FEATURES Location/Qualifiers
source 1..3213
/db_xref="H-InvDB:HIT000260084"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:71558 IMAGE:5298560"
/tissue_type="Testis"
/clone_lib="NIH_MGC_97"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..3213
/gene="LRRC8B"
/gene_synonym="KIAA0231"
/gene_synonym="TA-LRRP"
/db_xref="GeneID:23507"
CDS 450..2861
/gene="LRRC8B"
/gene_synonym="KIAA0231"
/gene_synonym="TA-LRRP"
/codon_start=1
/product="LRRC8B protein"
/protein_id="AAH60782.1"
/db_xref="GeneID:23507"
/translation="MITLTELKCLADAQSSYHILKPWWDVFWYYITLIMLLVAVLAGA
LQLTQSRVLCCLPCKVEFDNHCAVPWDILKASMNTSSNPGTPLPLPLRIQNDLHRQQY
SYIDAVCYEKQLHWFAKFFPYLVLLHTLIFAACSNFWLHYPSTSSRLEHFVAILHKCF
DSPWTTRALSETVAEQSVRPLKLSKSKILLSSSGCSADIDSGKQSLPYPQPGLESAGI
ESPTSSVLDKKEGEQAKAIFEKVKRFRMHVEQKDIIYRVYLKQIIVKVILFVLIITYV
PYFLTHITLEIDCSVDVQAFTGYKRYQCVYSLAEIFKVLASFYVILVILYGLTSSYSL
WWMLRSSLKQYSFEALREKSNYSDIPDVKNDFAFILHLADQYDPLYSKRFSIFLSEVS
ENKLKQINLNNEWTVEKLKSKLVKNAKDKIELHLFMLNGLPDNVFELTEMEVLSLELI
PEVKLPSAVSQLVNLKELRVYHSSLVVDHPALAFLEENLKILRLKFTEMGKIPRWVFH
LKNLKELYLSGCVLPEQLSTMQLEGFQDLKNLRTLYLKSSLSRIPQVVTDLLPSLQKL
SLDNEGSKLVVLNNLKKMVNLKSLELISCDLERIPHSIFSLNNLHELDLRENNLKTVE
EIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLEQLSLDHNNIENLPLQLFLCTKLH
YLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLPDGLFQCKKLQCLLLGKNSLMNL
SPHVGELSNLTHLELIGNYLETLPPELEGCQSLKRNCLIVEENLLNTLPLPVTERLQT
CLDKC"
BASE COUNT 867 a 760 c 718 g 868 t
ORIGIN
1 gcttcccgct gagcccgcag cctccggcag ccgggaaagt gcgggcgcgg ggccgcagcc
61 tgcccgcccg gagcggccca ggagcacgcc gcggggagcg cgggcgtccg gggctggagt
121 cgcgcagaat cctcagagtg aaaacaccaa caggctccag tttgtgtttt cagctgccta
181 ctagacctca ctacctggat ggcccacagg taatagttaa cctcttctgt gagaagtcag
241 aaggtgatct ctttaatgct ttctttttaa gaatttttca aattgagact aattgcagag
301 gttccagttg accagcattc ataggaatga agacaaacac agagatggtg tgtctaagaa
361 acttcaaaag gtgtagacct cctgactgaa gcatattgga tttatttaat ttttttcact
421 gtatttctgt cctcctacaa gggaaagtca tgattacact aactgagcta aaatgcttag
481 cagatgctca gtcatcttat cacatcttaa aaccatggtg ggacgtcttc tggtattaca
541 tcacactgat catgctgctg gtggccgtgc tggccggagc tctccagctg acgcagagca
601 gggttctgtg ctgtcttcca tgcaaagtgg aatttgacaa tcactgtgcc gtgccttggg
661 acatcctgaa agccagcatg aacacatcct ctaatcctgg gacaccgctt ccgctccccc
721 tccgaattca gaatgacctc caccgacagc agtactccta tattgatgcc gtctgttacg
781 agaaacagct ccattggttt gcaaagtttt tcccctatct ggtgctcttg cacacgctca
841 tctttgcagc ctgcagcaac ttttggcttc actaccccag taccagttcc aggctcgagc
901 attttgtggc catccttcac aagtgcttcg attctccatg gaccacccgc gccctttcag
961 aaacagtggc tgagcagtca gtgaggcctc tgaaactctc caagtccaag attttgcttt
1021 cgtcctcagg gtgttcagct gacatagatt ccggcaaaca gtcattgccc tacccacagc
1081 caggtttgga gtcagctggc atagaaagcc caacttccag tgtcctggac aagaaggagg
1141 gtgaacaggc caaagccatc tttgaaaaag tgaaaagatt ccgcatgcat gtggagcaga
1201 aggacatcat ttatagagta tatctgaaac agataatagt caaagtcatt ttgtttgtgc
1261 tcatcataac ttatgttcca tattttttaa cccacatcac tcttgaaatc gactgttcag
1321 ttgatgtgca ggcttttaca ggatataagc gctaccagtg tgtctattcc ttggcagaga
1381 tctttaaggt cctggcttca ttttatgtca ttttggttat actttatggt ctgacctctt
1441 cctacagcct gtggtggatg ctgaggagtt ccctgaagca atattccttt gaggcgttaa
1501 gagaaaaaag caactacagt gacatccctg atgtcaagaa tgactttgcc ttcatccttc
1561 atctggctga tcagtatgat cctctttatt ccaaacgctt ctccatattc ctatcagagg
1621 tcagtgagaa caaactgaaa cagatcaacc tcaataatga atggacagtt gagaaactga
1681 aaagtaagct tgtgaaaaat gccaaggaca agatagaact gcatcttttt atgctcaacg
1741 gtcttccaga caatgtcttt gagttaactg aaatggaagt gctaagcctg gagcttatcc
1801 cagaggtgaa gctgccctct gcagtctcac agctggtcaa cctcaaggag cttcgtgtgt
1861 accattcatc tctggtcgta gaccatcctg cactggcctt tctagaggag aatttaaaaa
1921 tcctccgcct gaaatttact gaaatgggaa aaatcccacg ctgggtattt cacctcaaga
1981 atctcaagga actttatctt tcgggctgtg ttctccctga acagttgagt actatgcagt
2041 tggagggctt tcaggactta aaaaatctaa ggaccctgta cttgaagagc agcctctccc
2101 ggatcccaca agttgttaca gacctcctgc cttcattgca gaaactgtcc cttgataatg
2161 agggaagcaa actggttgtg ttgaacaact tgaaaaagat ggtcaatctg aaaagcctag
2221 aactgatcag ctgtgacctg gaacgcatcc cacattccat tttcagcctg aataatttgc
2281 atgagttaga cctaagggaa aataacctta aaactgtgga agagatcatt agctttcagc
2341 atcttcagaa tctttcctgc ttaaagttgt ggcacaataa cattgcttat attcctgcac
2401 agattggggc attatctaac ctagagcagc tctctttgga ccataataat attgagaatc
2461 tgcccttgca gcttttccta tgcactaaac tacattattt ggatctaagc tataaccact
2521 tgaccttcat tccagaagaa atccagtatc tgagtaattt gcagtacttt gctgtgacca
2581 acaacaatat tgagatgcta ccagatgggc tgtttcagtg caaaaagctg cagtgtttac
2641 ttttggggaa aaatagcttg atgaatttgt cccctcatgt gggtgagctg tcaaacctta
2701 ctcatctgga gctcattggt aattacctgg aaacacttcc tcctgaacta gaaggatgtc
2761 agtccctaaa acggaactgt ctgattgttg aggagaactt gctcaatact cttcctctcc
2821 ctgtaacaga acgtttacag acgtgcttag acaaatgttg acttaaagaa aagagacccg
2881 tgtttcaaaa tcatttttaa aagtatgctc ggccgggcgt ggtggctcat gcctataatc
2941 ccagcacttt gggaggccaa gatgggcgga ttgcttgagg tcaggagttc gagaccagtc
3001 tggccaacct ggtgaaaccc catctctgct aaaactacaa aaaaattagc caggcgtggt
3061 ggcgtgcgcc tgtaatccca gctacttggg aggctgacgc aggggaattg cttgaaccag
3121 ggaggtggag gttgcagtga gccgagattg tgccactgta caccagcctg ggtgacagag
3181 caagactctt atctcagaaa aaaaaaaaaa aaa
//