LOCUS BC060762 3994 bp mRNA linear HUM 17-JUL-2006
DEFINITION Homo sapiens phosphodiesterase 8A, mRNA (cDNA clone MGC:71504
IMAGE:30344110), complete cds.
ACCESSION BC060762
VERSION BC060762.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3994)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3994)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (03-NOV-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Dr. Stefan Hansson
cDNA Library Preparation: Michael Brownstein / Ted Usdin
Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 133 Row: g Column: 8
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 47132535.
FEATURES Location/Qualifiers
source 1..3994
/db_xref="H-InvDB:HIT000260064"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:71504 IMAGE:30344110"
/tissue_type="Placenta, normal"
/clone_lib="NIH_MGC_147"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..3994
/gene="PDE8A"
/gene_synonym="HsT19550"
/db_xref="GeneID:5151"
/db_xref="HGNC:HGNC:8793"
/db_xref="MIM:602972"
CDS 253..2742
/gene="PDE8A"
/gene_synonym="HsT19550"
/codon_start=1
/product="phosphodiesterase 8A"
/protein_id="AAH60762.1"
/db_xref="GeneID:5151"
/db_xref="HGNC:HGNC:8793"
/db_xref="MIM:602972"
/translation="MGCAPSIHISERLVAEDAPSPAAPPLSSGGPRLPQGQKTAALPR
TRGAGLLESELRDGSGKKVAVADVQFGPMRFHQDQLQVLLVFTKEDNQCNGFCRACEK
AGFKCTVTKGAQAVLACFLDKHHDIIIIDHRNPRQLDAEALCRSIRSSKLSENTVIVG
VVRRVDREELSVMPFISAGFTRRYVENPNIMACYNELLQLEFGEVRSQLKLRACNSVF
TALENSEDAIEITSEDRFIQYANPAFETTMGYQSGELIGKELGEVPINEKKADLLDTI
NSCIRIGKEWQGIYYAKKKNGDNIQQNVKIIPVIGQGGKIRHYVSIIRVCNGNNKAEK
ISECVQSDTHTDNQTGKHKDRRKGSLDVKAVASRATEVSSQRRHSSMARIHSMTIEAP
ITKVINIINAAQESSPMPVTEALDRVLEILRTTELYSPQFGAKDDDPHANDLVGGLMS
DGLRRLSGNEYVLSTKNTQMVSSNIITPISLDDVPPRIARAMENEEYWDFDIFELEAA
THNRPLIYLGLKMFARFGICEFLHCSESTLRSWLQIIEANYHSSNPYHNSTHSADVLH
ATAYFLSKERIKETLDPIDEVAALIAATIHDVDHPGRTNSFLCNAGSELAILYNDTAV
LESHHAALAFQLTTGDDKCNIFKNMERNDYRTLRQGIIDMVLATEMTKHFEHVNKFVN
SINKPLATLEENGETDKNQEVINTMLRTPENRTLIKRMLIKCADVSNPCRPLQYCIEW
AARISEEYFSQTDEEKQQGLPVVMPVFDRNTCSIPKSQISFIDYFITDMFDAWDAFVD
LPDLMQHLDNNFKYWKGLDEMKLRNLRPPPE"
BASE COUNT 1181 a 918 c 886 g 1009 t
ORIGIN
1 agtagccggg ccaaggcggg agcggctgcc tctcagggtc gctccagggc cgcgctagga
61 aagccgccgc cgccgcagcg cccgcaccgc gataaaaggg gcggccgcgt ttcctgacgc
121 gagatccgcg ctcgccgccg cccgcccagg cggcgatgac acggcgcccg cggcggcccg
181 gaggcgccgg gtgggccgtt tgctgaccgg atcgcggcta cccgccagcg tgtccgcggc
241 gccgccgcca gcatgggctg tgccccgagc atccacattt ccgagcgcct ggtggccgag
301 gacgcgccta gccccgcggc accgccgctg tcgtccggcg ggccgcgcct cccgcagggc
361 cagaagacgg ccgccttgcc ccggacccgc ggcgccggcc tcttggagtc ggagcttcgc
421 gacggcagcg gcaagaaggt agcagtagct gatgtgcagt ttggccccat gagatttcat
481 caagatcaac ttcaggtact tttagtgttt accaaagaag ataaccaatg taatggattc
541 tgcagggcat gtgaaaaagc agggtttaag tgtacagtta ccaagggggc tcaggctgtc
601 cttgcctgtt tcctggacaa acatcatgac attatcatca tagaccacag aaatcctcga
661 cagctggatg cagaggcact gtgcaggtct atcagatcat caaaactctc agaaaacaca
721 gttattgttg gtgtagtacg cagggtggat agagaagagt tgtccgtaat gcctttcatt
781 tctgctggat ttacaaggag gtatgtagaa aaccccaaca tcatggcctg ctacaatgaa
841 ctgctccagc tggagtttgg agaggtgcga tcacaactga aactcagggc ttgtaactca
901 gtattcactg cattagaaaa cagtgaagat gcaattgaaa ttacaagcga agaccgtttt
961 atacagtatg caaatcctgc atttgaaaca acaatgggct atcagtcagg tgaattaata
1021 gggaaggagt taggagaagt gcctataaat gaaaaaaagg ctgacttgct cgatactata
1081 aattcatgca tcaggatagg caaggagtgg caaggaattt actatgccaa aaagaaaaac
1141 ggagataata tacaacaaaa tgtgaagata atacctgtca ttggacaggg aggaaaaatt
1201 agacactatg tgtccattat cagagtgtgc aatggcaaca ataaggctga gaaaatatcc
1261 gaatgtgttc agtctgacac tcatacagat aatcagacag gcaaacataa agacaggaga
1321 aaaggctcac tagacgtcaa agctgttgcc tcccgtgcaa ctgaagtttc cagccagaga
1381 cgacactctt ccatggcccg gatacattcc atgacaattg aggcgcccat caccaaggta
1441 atcaatatta tcaatgctgc ccaggaaagt agtcccatgc ctgtgacaga agccctagac
1501 cgtgtgctgg aaattctaag aaccactgag ttatattcac cacagtttgg tgctaaagat
1561 gatgatcccc atgccaatga ccttgttggg ggcttaatgt ctgatggttt gcgaagacta
1621 tcagggaatg aatatgttct ttcaacaaaa aacactcaaa tggtttcaag caatataatc
1681 actcccatct cccttgatga tgtcccacca cggatagctc gggccatgga aaatgaggaa
1741 tactgggact ttgatatttt tgaactggag gctgccaccc acaataggcc tttgatttat
1801 cttggtctca aaatgtttgc tcgctttgga atctgtgaat tcttacactg ctccgagtca
1861 acgctaagat catggttaca aattatcgaa gccaattatc attcctccaa tccctaccac
1921 aattctacac attctgctga tgtgcttcat gccactgcct attttctctc caaggagagg
1981 ataaaggaaa ctttagatcc aattgatgag gtcgctgcac tcatcgcagc caccattcat
2041 gatgtggatc accctgggag aaccaactcc ttcctgtgta atgctggaag tgagctggcc
2101 attttgtaca atgacactgc tgtgctggag agccaccatg cggccttggc cttccagctg
2161 accactggag atgataaatg caatatattt aaaaacatgg agaggaatga ttatcggaca
2221 ctgcgccagg ggattatcga catggtctta gccacagaaa tgacaaagca ctttgagcat
2281 gtcaacaaat ttgtcaacag catcaacaaa cccttggcaa cactagaaga aaatggggaa
2341 actgataaaa accaggaagt gataaacact atgcttagga ctccagagaa ccggacccta
2401 atcaaacgaa tgctgattaa atgtgctgat gtgtccaatc cctgccgacc cctgcagtac
2461 tgcatcgagt gggctgcacg catttcggaa gaatattttt ctcagactga tgaagagaag
2521 cagcagggct tacctgtggt gatgccagtg tttgacagaa atacctgcag catccccaaa
2581 tcccaaatct ctttcattga ttacttcatc acagacatgt ttgatgcttg ggatgccttt
2641 gtagacctgc ctgatttaat gcagcatctt gacaacaact ttaaatactg gaaaggactg
2701 gacgaaatga agctgcggaa cctccgacca cctcctgaat agtgggagac accacccaga
2761 gccctgaagc tttgttcctt cggtcatttg gaattcctga gggcagccag agctccttgg
2821 tcctttcagt actaggcaga acagcccccg atctgcatag cctgtgaaag cccacgggga
2881 catcagtaac cttctgcagc caccatccaa tgccattact gtcaagtgag acttggccac
2941 tgtagcctgg gcctgctgca ggagctcttc agaaaggcac atgaggacca cggtttgcct
3001 cagtttctgg taaaacacaa ggtctggagt gcccctgcaa agggtattga tggacttcct
3061 gccagtgaca gagcatgtct attgcaaaca attctctcag ttacgttcag cacttaagaa
3121 cggctaatgg caataggatc tttagcaact ttttcacatc atagaaggtg caatcgctca
3181 cttgggaaca ctactgagag tgacttctct tttaaaattg agtagcagat gaaaaattaa
3241 aatttgaact tgattattaa tatcaattaa aatgttttat ttattttatt aaaagctcaa
3301 tattttctat gaattcaaaa atacttcaga gccaaagcca acttcaaata ccgtgaccaa
3361 atttacatga ttcatattca ttatgcatta cttggtatac agacttattt tcataatgca
3421 aattaataaa atgacacttt tactgcacta tagaaatatt catgtatgtt aaacttttct
3481 gattgaggct aactggaaaa agctggggtc gtattctaag tgctaaagaa ggctgcttct
3541 actgtataga acccagggct ctgaaacagc tctagccgcc taatgcactt cacaggtaac
3601 tccccaaggt aaaactagac tctcttgttg gttcgcaaag aaaagttagg acttaacact
3661 tttttctaaa attttataat tcaatttcca aaagtctact ctattttata ctgtttctac
3721 aaaatattcc ttataaaaac aaagaacaaa aattgaatat ttaatgaatt gacattttat
3781 aaccaacctg tttttatcta cggtgggaat ctttgatgcc agaaatttat aaagaggttc
3841 tgtatcttca caccttgaat aagcataata ccataaaaaa tgacacttga catgtcaatg
3901 tatttgtcat ttcattttaa actcgtattt gtggtttttt tcccagataa aaatgaaatt
3961 aaaccatttc tttttaagaa aaaaaaaaaa aaaa
//