LOCUS BC059392 3162 bp mRNA linear HUM 17-JUL-2006
DEFINITION Homo sapiens prolactin receptor, mRNA (cDNA clone MGC:71713
IMAGE:30343995), complete cds.
ACCESSION BC059392
VERSION BC059392.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3162)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3162)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (01-OCT-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Dr. Stefan Hansson
cDNA Library Preparation: Michael Brownstein / Ted Usdin
Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 133 Row: g Column: 13
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 40254435.
FEATURES Location/Qualifiers
source 1..3162
/db_xref="H-InvDB:HIT000259992"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:71713 IMAGE:30343995"
/tissue_type="Placenta, normal"
/clone_lib="NIH_MGC_147"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..3162
/gene="PRLR"
/gene_synonym="hPRLrI"
/db_xref="GeneID:5618"
/db_xref="HGNC:HGNC:9446"
/db_xref="MIM:176761"
CDS 314..2182
/gene="PRLR"
/gene_synonym="hPRLrI"
/codon_start=1
/product="prolactin receptor"
/protein_id="AAH59392.1"
/db_xref="GeneID:5618"
/db_xref="HGNC:HGNC:9446"
/db_xref="MIM:176761"
/translation="MKENVASATVFTLLLFLNTCLLNGQLPPGKPEIFKCRSPNKETF
TCWWRPGTDGGLPTNYSLTYHREGETLMHECPDYITGGPNSCHFGKQYTSMWRTYIMM
VNATNQMGSSFSDELYVDVTYIVQPDPPLELAVEVKQPEDRKPYLWIKWSPPTLIDLK
TGWFTLLYEIRLKPEKAAEWEIHFAGQQTEFKILSLHPGQKYLVQVRCKPDHGYWSAW
SPATFIQIPSDFTMNDTTVWISVAVLSAVICLIIVWAVALKGYSMVTCIFPPVPGPKI
KGFDAHLLEKGKSEELLSALGCQDFPPTSDYEDLLVEYLEVDDSEDQHLMSVHSKEHP
SQGMKPTYLDPDTDSGRGSCDSPSLLSEKCEEPQANPSTFYDPEVIEKPENPETTHTW
DPQCISMEGKIPYFHAGGSKCSTWPLPQPSQHNPRSSYHNITDVCELAVGPAGAPATL
LNEAGKDALKSSQTIKSREEGKATQQREVESFHSETDQDTPWLLPQEKTPFGSAKPLD
YVEIHKVNKDGALSLLPKQRENSGKPKKPGTPENNKEYAKVSGVMDNNILVLVPDPHA
KNVACFEESAKEAPPSLEQNQAEKALANFTATSSKCRLQLGGLDYLDPACFTHSFH"
BASE COUNT 943 a 731 c 654 g 834 t
ORIGIN
1 agagccaccg ggctggggac cggggagcgg aggctgaaat ccccagacgc cggttttctg
61 ggctgggctt tctgccttac tcactccttc tccctctttc tggattttac cgaccgttcg
121 cgaaacagct ttccacacaa tggagcttca tgtcctcgtg caggaagtac tcatcgactg
181 atgtggcaga ctttgctccc tggcaaaact aaagaactct cctattcatg gaggcgaaca
241 ctgaggatgc tttccacatg aaccctgaag tgaacttctg atacatttcc tgcagcaaga
301 gaaggcagcc aacatgaagg aaaatgtggc atctgcaacc gttttcactc tgctactttt
361 tctcaacacc tgccttctga atggacagtt acctcctgga aaacctgaga tctttaaatg
421 tcgttctccc aataaggaaa cattcacctg ctggtggagg cctgggacag atggaggact
481 tcctaccaat tattcactga cttaccacag ggaaggagag acactcatgc atgaatgtcc
541 agactacata accggtggcc ccaactcctg ccactttggc aagcagtaca cctccatgtg
601 gaggacatac atcatgatgg tcaatgccac taaccagatg ggaagcagtt tctcggatga
661 actttatgtg gacgtgactt acatagttca gccagaccct cctttggagc tggctgtgga
721 agtaaaacag ccagaagaca gaaaacccta cctgtggatt aaatggtctc cacctaccct
781 gattgactta aaaactggtt ggttcacgct cctgtatgaa attcgattaa aacccgagaa
841 agcagctgag tgggagatcc attttgctgg gcagcaaaca gagtttaaga ttctcagcct
901 acatccagga cagaaatacc ttgtccaggt tcgctgcaaa ccagaccatg gatactggag
961 tgcatggagt ccagcgacct tcattcagat acctagtgac ttcaccatga atgatacaac
1021 cgtgtggatc tctgtggctg tcctttctgc tgtcatctgt ttgattattg tctgggcagt
1081 ggctttgaag ggctatagca tggtgacctg catctttccg ccagttcctg ggccaaaaat
1141 aaaaggattt gatgctcatc tgttggagaa gggcaagtct gaagaactac tgagtgcctt
1201 gggatgccaa gactttcctc ccacttctga ctatgaggac ttgctggtgg agtatttaga
1261 agtagatgat agtgaggacc agcatctaat gtcagtccat tcaaaagaac acccaagtca
1321 aggtatgaaa cccacatacc tggatcctga cactgactca ggccggggga gctgtgacag
1381 cccttccctt ttgtctgaaa agtgtgagga accccaggcc aatccctcca cattctatga
1441 tcctgaggtc attgagaagc cagagaatcc tgaaacaacc cacacctggg acccccagtg
1501 cataagcatg gaaggcaaaa tcccctattt tcatgctggt ggatccaaat gttcaacatg
1561 gcccttacca cagcccagcc agcacaaccc cagatcctct taccacaata ttactgatgt
1621 gtgtgagctg gctgtgggcc ctgcaggtgc accggccact ctgttgaatg aagcaggtaa
1681 agatgcttta aaatcctctc aaaccattaa gtctagagaa gagggaaagg caacccagca
1741 gagggaggta gaaagcttcc attctgagac tgaccaggat acgccctggc tgctgcccca
1801 ggagaaaacc ccctttggct ccgctaaacc cttggattat gtggagattc acaaggtcaa
1861 caaagatggt gcattatcat tgctaccaaa acagagagag aacagcggca agcccaagaa
1921 gcccgggact cctgagaaca ataaggagta tgccaaggtg tccggggtca tggataacaa
1981 catcctggtg ttggtgccag atccacatgc taaaaacgtg gcttgctttg aagaatcagc
2041 caaagaggcc ccaccatcac ttgaacagaa tcaagctgag aaagccctgg ccaacttcac
2101 tgcaacatca agcaagtgca ggctccagct gggtggtttg gattacctgg atcccgcatg
2161 ttttacacac tcctttcact gatagcttga ctaatggaat gattggttaa aatgtgattt
2221 ttcttcaggt aacactacag agtacgtgaa atgctcaaga atgtagtcag actgacacta
2281 ctaaagctcc cagctccttt catgctccat ttttaaccac ttgcctcttt ctccagcagc
2341 tgattccaga acaaatcatt atgtttccta actgtgattt gtagatttac tttttgctgt
2401 tagttataaa actatgtgtt caatgaaata aaagcacact gcttagtatt cttgagggac
2461 aatgccaata ggtatatcct ctggaaaagg ctttcatgat ttgacatggg acagacggaa
2521 atgaaattgt caaaattgtt taccatagaa agatgacaaa agaaaatttt ccacatagga
2581 aaatgccatg aaaattgctt ttgaaaaaca actgcataac ctttacactc ctcgtccatt
2641 ttattaggat tacccaaata taaccattta aagaaagaat gcattccaga acaaattgtt
2701 tacataagtt cctatacctt actgacacat tgctgatatg caagtaagaa ataatgcctc
2761 caattttttt cttaaaatag tttagatatg ttaagcatgg attttccccc taaattctac
2821 tctaaagctt ctataaaata tagtttggaa ataaaaatgt tcttacacaa ggggcaaatg
2881 aatttcatgt gaatcccttt aggatgtttt cctccttcat ttcagcatga tagataattt
2941 attatacacc ttagtctttc cttagttaaa aaaaaattcc ctaaagacta acttgaaaag
3001 aaaaccacag caggatgcta atggaattac tgccttactg tacatacaaa ttctacttta
3061 atataaaccc ataagtttaa ctgtattttt gaagactatt tttctatgac ttaggtaaaa
3121 taaaagacta ttttctattt tcccagaaaa aaaaaaaaaa aa
//