LOCUS BC059372 2711 bp mRNA linear HUM 28-JUL-2005
DEFINITION Homo sapiens toll-like receptor 3, mRNA (cDNA clone
IMAGE:30337077), partial cds.
ACCESSION BC059372
VERSION BC059372.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2711)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2711)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (01-OCT-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Dr. Stefan Hansson
cDNA Library Preparation: Michael Brownstein / Ted Usdin
Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 133 Row: c Column: 5
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 19718735.
FEATURES Location/Qualifiers
source 1..2711
/db_xref="H-InvDB:HIT000259972"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:30337077"
/tissue_type="Placenta, pre-eclamptic"
/clone_lib="NIH_MGC_148"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..>2711
/gene="TLR3"
/db_xref="GeneID:7098"
/db_xref="MIM:603029"
CDS 101..>2711
/gene="TLR3"
/codon_start=1
/product="TLR3 protein"
/protein_id="AAH59372.1"
/db_xref="GeneID:7098"
/db_xref="MIM:603029"
/translation="MRQTLPCIYFWGGLLPFGMLCASSTTKCTVSHEVADCSHLKLTQ
VPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLK
VLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLS
STKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFH
AIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNL
TMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFT
KQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTS
LRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQ
EWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL
TILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHI
LNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITS
VEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPH
YHGFPVRLFDTSSCKDSAPFELFFMINTSILLIFIFIVLLIHFEGWRISFYWNVSVHR
VLGFKEIDRQTEQFEYAAYIIHAYKDKDWVWEHFSSMEKEDQSLKFCLEERDFEAGVF
ELEAIVNSIKRSRKIIFVITHHLLKDPLCKRFKVHHAVQQAIEQNLDSIILVFLEEIP
DYKLNHALSKKKKK"
BASE COUNT 839 a 590 c 487 g 795 t
ORIGIN
1 gctttcgaga gtgccgtcta tttgccacac acttccctga tgaaatgtct ggatttggac
61 taaagaaaaa aggaaaggct agcagtcatc caacagaatc atgagacaga ctttgccttg
121 tatctacttt tgggggggcc ttttgccctt tgggatgctg tgtgcatcct ccaccaccaa
181 gtgcactgtt agccatgaag ttgctgactg cagccacctg aagttgactc aggtacccga
241 tgatctaccc acaaacataa cagtgttgaa ccttacccat aatcaactca gaagattacc
301 agccgccaac ttcacaaggt atagccagct aactagcttg gatgtaggat ttaacaccat
361 ctcaaaactg gagccagaat tgtgccagaa acttcccatg ttaaaagttt tgaacctcca
421 gcacaatgag ctatctcaac tttctgataa aacctttgcc ttctgcacga atttgactga
481 actccatctc atgtccaact caatccagaa aattaaaaat aatccctttg tcaagcagaa
541 gaatttaatc acattagatc tgtctcataa tggcttgtca tctacaaaat taggaactca
601 ggttcagctg gaaaatctcc aagagcttct attatcaaac aataaaattc aagcgctaaa
661 aagtgaagaa ctggatatct ttgccaattc atctttaaaa aaattagagt tgtcatcgaa
721 tcaaattaaa gagttttctc cagggtgttt tcacgcaatt ggaagattat ttggcctctt
781 tctgaacaat gtccagctgg gtcccagcct tacagagaag ctatgtttgg aattagcaaa
841 cacaagcatt cggaatctgt ctctgagtaa cagccagctg tccaccacca gcaatacaac
901 tttcttggga ctaaagtgga caaatctcac tatgctcgat ctttcctaca acaacttaaa
961 tgtggttggt aacgattcct ttgcttggct tccacaacta gaatatttct tcctagagta
1021 taataatata cagcatttgt tttctcactc tttgcacggg cttttcaatg tgaggtacct
1081 gaatttgaaa cggtctttta ctaaacaaag tatttccctt gcctcactcc ccaagattga
1141 tgatttttct tttcagtggc taaaatgttt ggagcacctt aacatggaag ataatgatat
1201 tccaggcata aaaagcaata tgttcacagg attgataaac ctgaaatact taagtctatc
1261 caactccttt acaagtttgc gaactttgac aaatgaaaca tttgtatcac ttgctcattc
1321 tcccttacac atactcaacc taaccaagaa taaaatctca aaaatagaga gtgatgcttt
1381 ctcttggttg ggccacctag aagtacttga cctgggcctt aatgaaattg ggcaagaact
1441 cacaggccag gaatggagag gtctagaaaa tatttttgaa atctatcttt cctacaacaa
1501 gtacctgcag ctgactagga actcctttgc cttggtccca agccttcaac gactgatgct
1561 ccgaagggtg gcccttaaaa atgtggatag ctctccttca ccattccagc ctcttcgtaa
1621 cttgaccatt ctggatctaa gcaacaacaa catagccaac ataaatgatg acatgttgga
1681 gggtcttgag aaactagaaa ttctcgattt gcagcataac aacttagcac ggctctggaa
1741 acacgcaaac cctggtggtc ccatttattt cctaaagggt ctgtctcacc tccacatcct
1801 taacttggag tccaacggct ttgacgagat cccagttgag gtcttcaagg atttatttga
1861 actaaagatc atcgatttag gattgaataa tttaaacaca cttccagcat ctgtctttaa
1921 taatcaggtg tctctaaagt cattgaacct tcagaagaat ctcataacat ccgttgagaa
1981 gaaggttttc gggccagctt tcaggaacct gactgagtta gatatgcgct ttaatccctt
2041 tgattgcacg tgtgaaagta ttgcctggtt tgttaattgg attaacgaga cccataccaa
2101 catccctgag ctgtcaagcc actacctttg caacactcca cctcactatc atgggttccc
2161 agtgagactt tttgatacat catcttgcaa agacagtgcc ccctttgaac tctttttcat
2221 gatcaatacc agtatcctgt tgatttttat ctttattgta cttctcatcc actttgaggg
2281 ctggaggata tctttttatt ggaatgtttc agtacatcga gttcttggtt tcaaagaaat
2341 agacagacag acagaacagt ttgaatatgc agcatatata attcatgcct ataaagataa
2401 ggattgggtc tgggaacatt tctcttcaat ggaaaaggaa gaccaatctc tcaaattttg
2461 tctggaagaa agggactttg aggcgggtgt ttttgaacta gaagcaattg ttaacagcat
2521 caaaagaagc agaaaaatta tttttgttat aacacaccat ctattaaaag acccattatg
2581 caaaagattc aaggtacatc atgcagttca acaagctatt gaacaaaatc tggattccat
2641 tatattggtt ttccttgagg agattccaga ttataaactg aaccatgcac tctcgaaaaa
2701 aaaaaaaaaa a
//