LOCUS BC059170 1371 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens hydroxysteroid (17-beta) dehydrogenase 2, mRNA (cDNA
clone MGC:14632 IMAGE:4079440), complete cds.
ACCESSION BC059170
VERSION BC059170.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1371)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1371)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (01-OCT-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: CLONTECH Laboratories, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 21 Row: o Column: 19
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 4504502.
FEATURES Location/Qualifiers
source 1..1371
/db_xref="H-InvDB:HIT000259951"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:14632 IMAGE:4079440"
/tissue_type="Bone marrow, acute myelogenous leukemia"
/clone_lib="NIH_MGC_55"
/lab_host="DH10B"
/note="Vector: pDNR-LIB"
gene 1..1371
/gene="HSD17B2"
/gene_synonym="EDH17B2"
/gene_synonym="HSD17"
/db_xref="GeneID:3294"
/db_xref="HGNC:HGNC:5211"
/db_xref="MIM:109685"
CDS 86..1249
/gene="HSD17B2"
/gene_synonym="EDH17B2"
/gene_synonym="HSD17"
/codon_start=1
/product="hydroxysteroid (17-beta) dehydrogenase 2"
/protein_id="AAH59170.1"
/db_xref="GeneID:3294"
/db_xref="HGNC:HGNC:5211"
/db_xref="MIM:109685"
/translation="MSTFFSDTAWICLAVPTVLCGTVFCKYKKSSGQLWSWMVCLAGL
CAVCLLILSPFWGLILFSVSCFLMYTYLSGQELLPVDQKAVLVTGGDCGLGHALCKYL
DELGFTVFAGVLNENGPGAEELRRTCSPRLSVLQMDITKPVQIKDAYSKVAAMLQDRG
LWAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGTVEVTKTFLPLLRKSKGRLVNVS
SMGGGAPMERLASYGSSKAAVTMFSSVMRLELSKWGIKVASIQPGGFLTNIAGTSDKW
EKLEKDILDHLPAEVQEDYGQDYILAQRNFLLLINSLASKDFSPVLRDIQHAILAKSP
FAYYTPGKGAYLWICLAHYLPIGIYDYFAKRHFGQDKPMPRALRMPNYKKKAT"
BASE COUNT 359 a 323 c 355 g 334 t
ORIGIN
1 gacagaactc aggctgcctc cagccagcct ttgcccgcta gactcactgg ccctgagcac
61 ttgaaggtgc agcaagtcac tgagaatgag cactttcttc tcggacacag catggatctg
121 cctggctgtc cccacagtac tatgtgggac agtattttgc aaatacaaga agagctcagg
181 gcagctgtgg agctggatgg tctgcctggc aggcctctgt gcagtctgcc tgctcatcct
241 gtcccctttt tggggcttga tcctcttctc ggtgtcatgc ttcctcatgt atacttactt
301 atctggccaa gaattgttac ctgtggatca gaaggcagtc ctggtgacag gtggtgattg
361 cgggcttggc catgctttgt gcaagtatct ggatgagctg ggcttcacgg tatttgccgg
421 agttttgaat gaaaatggcc caggagctga ggaattgcga agaacctgct ctccgcgcct
481 ctcggtgctc caaatggaca tcacgaagcc agtgcagata aaagatgctt acagcaaggt
541 tgcagcaatg ctgcaggaca gaggactgtg ggctgtgatc aacaatgctg gggtgcttgg
601 ctttccaact gatggggagc ttcttcttat gactgactac aaacaatgca tggccgtgaa
661 cttctttgga actgtggagg tcacaaagac gtttttgcct cttcttagaa aatccaaagg
721 gaggctggtg aatgtcagca gcatgggagg aggggcccca atggaaaggc tggcatctta
781 tggctcatca aaggcggctg tgaccatgtt ctcatcagtt atgagactgg agctttccaa
841 gtggggaatt aaagttgctt ccatccaacc tggaggcttc ctaacaaata tcgcaggcac
901 cagtgacaag tgggaaaagc tggagaagga cattctggac cacctccccg ctgaggtaca
961 ggaagactac ggccaggact acatcttagc acagcggaat ttcctcctat tgatcaactc
1021 gttagccagc aaggacttct ctccggtgct gcgggacatc cagcatgcta tcttggcgaa
1081 gagccctttt gcctattaca cgccagggaa aggcgcttac ttgtggatct gccttgctca
1141 ctatttgcct attggcatat atgattactt tgctaaaaga cattttggcc aagacaagcc
1201 catgcccaga gctctaagaa tgcctaacta caagaaaaag gccacctagg caatggaagc
1261 cctcaaagaa gtcggaatgt catagtcttg aaatgaaagg gaaactggga aactgggttt
1321 ctcattaaag ttgtttccca ctcaaaaaaa aaaaaaaaaa aaaaaaaaaa a
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