LOCUS BC058884 2248 bp mRNA linear HUM 27-NOV-2018
DEFINITION Homo sapiens kelch-like 5 (Drosophila), mRNA (cDNA clone
IMAGE:6503663), partial cds.
ACCESSION BC058884
VERSION BC058884.2
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2248)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2248)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (01-OCT-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
REFERENCE 3 (bases 1 to 2248)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (27-NOV-2018) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK Sequence update by database staff to remove vector contamination
COMMENT On Nov 27, 2018 this sequence version replaced BC058884.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Steven Jones, Jennifer Asano, Ian Bosdet, Yaron Butterfield,
Susanna Chan, Readman Chiu, Chris Fjell, Erin Garland, Ran Guin,
Letticia Hsiao, Martin Krzywinski, Reta Kutsche, Oliver Lee, Soo
Sen Lee, Victor Ling, Carrie Mathewson, Candice McLeavy, Steven
Ness, Pawan Pandoh, Anna-Liisa Prabhu, Parvaneh Saeedi, Jacqueline
Schein, Duane Smailus, Michael Smith, Lorraine Spence, Jeff Stott,
Michael Thorne, Miranada Tsai, Natasja van den Bosch, Jill Vardy,
George Yang, Scott Zuyderduyn, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 119 Row: p Column: 15.
FEATURES Location/Qualifiers
source 1..2248
/db_xref="H-InvDB:HIT000259894"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:6503663"
/tissue_type="Uterus, leiomyosarcoma"
/clone_lib="NIH_MGC_71"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene <1..2248
/gene="KLHL5"
/db_xref="GeneID:51088"
CDS <1..1033
/gene="KLHL5"
/codon_start=2
/product="KLHL5 protein"
/protein_id="AAH58884.2"
/db_xref="GeneID:51088"
/translation="LLAPQFLADMENNVLFRDDIECQKLIMEAMKYHLLPERRPMLQS
PRTKPRKSTVGTLFAVGGMDSTKGATSIEKYDLRTNMWTPVANMNGRRLQFGVAVLDD
KLYVVGGRDGLKTLNTVECYNPKTKTWSVMPPMSTHRHGLGVAVLEGPMYAVGGHDGW
SYLNTVERWDPQARQWNFVATMSTPRSTVGVAVLSGKLYAVGGRDGSSCLKSVECFDP
HTNKWTLCAQMSKRRGGVGVTTWNGLLYAIGGHDAPASNLTSRLSDCVERYDPKTDMW
TAVASMSISRDAVGVCLLGDKLYAVGGYDGQAYLNTVEAYDPQTNEWTQVAPLCLGRA
GACVVTVKL"
misc_feature 293..430
/gene="KLHL5"
/note="Kelch; Region: Kelch motif. The kelch motif was
initially discovered in Kelch. In this protein there are
six copies of the motif. It has been shown that one member
is related to Galactose Oxidase for which a structure has
been solved. The kelch motif forms a beta sheet. Several
of these sheets associate to form a beta propeller
structure as found in pfam00064, pfam00400 and pfam00415"
/db_xref="CDD:pfam01344"
BASE COUNT 738 a 362 c 465 g 683 t
ORIGIN
1 tcttcttgca ccacagttcc tggcagacat ggaaaataat gtactttttc gggatgatat
61 agaatgtcag aaactcatta tggaagcaat gaagtaccat ttattaccag agagacgacc
121 catgttacaa agtcctcgga caaaacctag gaagtcaact gttggtacat tatttgcagt
181 tgggggaatg gattcaacaa aaggagcaac aagcattgaa aagtatgatc tccgtacaaa
241 tatgtggact ccagtagcaa atatgaatgg gaggaggcta cagttcggtg ttgcagtgct
301 agatgacaaa ctgtatgtgg ttggaggaag agatggactg aagactttga atactgtaga
361 gtgctacaac cccaaaacaa aaacttggag tgtgatgcca cctatgtcca cacatagaca
421 tggccttggt gtggctgtac tggaaggtcc catgtatgcc gtaggaggac atgatggctg
481 gagctatctg aacacagtgg aaagatggga ccctcaggct cgccagtgga attttgttgc
541 cactatgtct acccctagga gtacagtagg tgtggcagta ctaagtggaa aactttatgc
601 agttggtggt cgtgatggaa gttcttgtct caaatcagta gaatgttttg atcctcatac
661 taataagtgg acactgtgtg cacagatgtc aaaaaggaga ggtggcgtag gagtgacgac
721 ctggaatgga ctgctgtatg ctataggggg gcacgatgct cccgcatcca acttgacttc
781 cagactctca gactgtgtgg aaagatatga tcccaaaaca gacatgtgga ctgcagtagc
841 atccatgagc atcagcagag atgcagtggg ggtctgttta cttggtgata agttatatgc
901 tgttgggggg tatgatggac aggcatacct taatactgtg gaggcttatg atccccagac
961 aaatgagtgg acccaggttg ctccactgtg cctaggaaga gctggagctt gtgttgtgac
1021 tgtaaaatta taatttagtg ccccgttttc tacatgaaga caccgtcttc ctttattaat
1081 ttagtataat tattctatca atggatacat ttttagtaaa tgtgcattgt cacaatcctg
1141 ggcacaaagt gcctgatgtc aaaatgaaga tagtaaaaca agggaggaag cagtggatgg
1201 accaggatta attcctttca tttcttagta aattaaaacc tgcagctggt ggattgtgat
1261 cacacattcc cgaagtaata agtgaggacg aatgcactgc tctggaacat aacccagtgc
1321 taactggggg tttcatttat tcagtcaagc acatcttact cacatccaga tttattttcc
1381 tacagtgcaa acacaccaga tgaaacttta aaatgttact ttttgtaagc ttatcataaa
1441 tgagttgcag taatttgttt gcttgtttgt ttaaccacaa ccactatttt aatgatatac
1501 taaagataac actatttagt tttttcagaa acatctgcat tatatgtgtg ttggttgtgg
1561 attttgtttc taaaattggc ttagtccaat aaataaagaa aagcattaag gacttaaagc
1621 aacaataacc aaataaaaac ttgataggat ctttgaagtc tatttaaata ttcattccat
1681 tacatctaga ctcaccaaga actacatgtt atgatgttaa gttgaagttg aaacatgatg
1741 ttttgcatta aatttaagat atgcaaattt atgtagagaa aataaatgtt atatacccta
1801 taatctttca cctaattagt atttaattat atggatttgt tttatattat aaaagatgtt
1861 ttgattttgt cttttgatat tgacaaaatt gtttggatat ccttatgttc tcaagtctgt
1921 atctgcctcc cctgccttat ttcttatgtt ttgccacagt taacccattg tgcttctttg
1981 taatcaaaca gtttgtggga gaatgggctt attgaatgtc taaaaaataa gtttaaagtg
2041 tttgttaccc taagtttttt acatttttaa actctaatta catatgtgaa tgttattact
2101 ctcagtgaat tgttattgtt tgcaaaaatg cactgggcag taacattttg tgataaatcc
2161 tataagatat aagtcaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
2221 aaaaaaaaaa aaaaaaaaaa aaaaaaaa
//