LOCUS       BC057828                 823 bp    mRNA    linear   HUM 17-JUL-2006
DEFINITION  Homo sapiens profilin 1, mRNA (cDNA clone MGC:71801
            IMAGE:30337970), complete cds.
ACCESSION   BC057828
VERSION     BC057828.1
KEYWORDS    MGC.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 823)
  AUTHORS   Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
            Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
            Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
            Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
            Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
            Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
            Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
            Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
            Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
            McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
            Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
            Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
            Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
            Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
            Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
            Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
            Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
            Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
  CONSRTM   Mammalian Gene Collection Program Team
  TITLE     Generation and initial analysis of more than 15,000 full-length
            human and mouse cDNA sequences
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
   PUBMED   12477932
REFERENCE   2  (bases 1 to 823)
  CONSRTM   NIH MGC Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-SEP-2003) National Institutes of Health, Mammalian
            Gene Collection (MGC), Bethesda, MD 20892-2590, USA
  REMARK    NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT     Contact: MGC help desk
            Email: cgapbs-r@mail.nih.gov
            Tissue Procurement: Dr. Stefan Hansson
            cDNA Library Preparation: Michael Brownstein /  Ted Usdin
            Laboratory
            cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
            DNA Sequencing by: Sequencing Group at the Stanford Human Genome
            Center, Stanford University School of Medicine, Stanford, CA  94305
            Web site:       http://www-shgc.stanford.edu
            Contact:  (Dickson, Mark) mcd@paxil.stanford.edu
            Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
            R. M.
            
            Clone distribution: MGC clone distribution information can be found
            through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
            Series: IRAK Plate: 133 Row: c Column: 12
            This clone was selected for full length sequencing because it
            passed the following selection criteria: matched mRNA gi: 31745179.
FEATURES             Location/Qualifiers
     source          1..823
                     /db_xref="H-InvDB:HIT000259765"
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /clone="MGC:71801 IMAGE:30337970"
                     /tissue_type="Placenta, pre-eclamptic"
                     /clone_lib="NIH_MGC_148"
                     /lab_host="DH10B"
                     /note="Vector: pBluescriptR"
     gene            1..823
                     /gene="PFN1"
                     /db_xref="GeneID:5216"
                     /db_xref="HGNC:HGNC:8881"
                     /db_xref="MIM:176610"
     CDS             142..564
                     /gene="PFN1"
                     /codon_start=1
                     /product="profilin 1"
                     /protein_id="AAH57828.1"
                     /db_xref="GeneID:5216"
                     /db_xref="HGNC:HGNC:8881"
                     /db_xref="MIM:176610"
                     /translation="MAGWNAYIDNLMADGTCQDAAIVGYKDSPSVWAAVPGKTFVNIT
                     PAEVGVLVGKDRSSFYVNGLTLGGQKCSVIRDSLLQDGEFSMDLRTKSTGGAPTFNVT
                     VTKTDKTLVLLMGKEGVHGGLINKKCYEMASHLRRSQY"
BASE COUNT          179 a          259 c          214 g          171 t
ORIGIN      
        1 gctgcacagc gagcggagcc gcggtccgga cggcagcgcg tgccccgagc tctccgcctc
       61 cccccgcccg ccagccgagg cagctcgagc ccagtccgcg gccccagcag cagcgccgag
      121 agcagcccca gtagcagcgc catggccggg tggaacgcct acatcgacaa cctcatggcg
      181 gacgggacct gtcaggacgc ggccatcgtg ggctacaagg actcgccctc cgtctgggcc
      241 gccgtccccg ggaaaacgtt cgtcaacatc acgccagctg aggtgggtgt cctggttggc
      301 aaagaccggt caagttttta cgtgaatggg ctgacacttg ggggccagaa atgttcggtg
      361 atccgggact cactgctgca ggatggggaa tttagcatgg atcttcgtac caagagcacc
      421 ggtggggccc ccaccttcaa tgtcactgtc accaagactg acaagacgct agtcctgctg
      481 atgggcaaag aaggtgtcca cggtggtttg atcaacaaga aatgttatga aatggcctcc
      541 caccttcggc gttcccagta ctgacctcgt ctgtcccttc cccttcaccg ctccccacag
      601 ctttgcaccc ctttcctccc catacacaca caaaccattt tattttttgg gccattaccc
      661 catacccctt attgctgcca aaaccacatg ggctgggggc cagggctgga tggacagaca
      721 cctcccccta cccatatccc tcccgtgtgt ggttggaaaa cttttgtttt ttggggtttt
      781 ttttttctga ataaaaaaga ttctactaaa aaaaaaaaaa aaa
//