LOCUS BC057800 2353 bp mRNA linear HUM 17-JUL-2006
DEFINITION Homo sapiens interleukin-1 receptor-associated kinase 3, mRNA (cDNA
clone MGC:71682 IMAGE:30335802), complete cds.
ACCESSION BC057800
VERSION BC057800.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2353)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2353)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (03-SEP-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Dr. Stefan Hansson
cDNA Library Preparation: Michael Brownstein / Ted Usdin
Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 133 Row: b Column: 6
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 6005791.
FEATURES Location/Qualifiers
source 1..2353
/db_xref="H-InvDB:HIT000259737"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:71682 IMAGE:30335802"
/tissue_type="Placenta, pre-eclamptic"
/clone_lib="NIH_MGC_148"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..2353
/gene="IRAK3"
/gene_synonym="IRAK-M"
/db_xref="GeneID:11213"
/db_xref="HGNC:HGNC:17020"
/db_xref="MIM:604459"
CDS 78..1868
/gene="IRAK3"
/gene_synonym="IRAK-M"
/codon_start=1
/product="interleukin-1 receptor-associated kinase 3"
/protein_id="AAH57800.1"
/db_xref="GeneID:11213"
/db_xref="HGNC:HGNC:17020"
/db_xref="MIM:604459"
/translation="MAGNCGARGALSAHTLLFDLPPALLGELCAVLDSCDGALGWRGL
AERLSSSWLDVRHIEKYVDQGKSGTRELLWSWAQKNKTIGDLLQVLQEMGHRRAIHLI
TNYGAVLSPSEKSYQEGGFPNILFKETANVTVDNVLIPEHNEKGVLLKSSISFQNIIE
GTRNFHKDFLIGEGEIFEVYRVEIQNLTYAVKLFKQEKKMQCKKHWKRFLSELEVLLL
FHHPNILELAAYFTETEKFCLIYPYMRNGTLFDRLQCVGDTAPLPWHIRIGILIGISK
AIHYLHNVQPCSVICGSISSANILLDDQFQPKLTDFAMAHFRSHLEHQSCTINMTSSS
SKHLWYMPEEYIRQGKLSIKTDVYSFGIVIMEVLTGCRVVLDDPKHIQLRDLLRELME
KRGLDSCLSFLDKKVPPCPRNFSAKLFCLAGRCAATRAKLRPSMDEVLNTLESTQASL
YFAEDPPTSLKSFRCPSPLFLENVPSIPVEDDESQNNNLLPSDEGLRIDRMTQKTPFE
CSQSEVMFLSLDKKPESKRNEEACNMPSSSCEESWFPKYIVPSQDLRPYKVNIDPSSE
APGHSCRSRPVESSCSSKFSWDEYEQYKKE"
BASE COUNT 718 a 495 c 532 g 608 t
ORIGIN
1 gcggttgtgt aacggcctgt cgcaggcgtg cagggacctg gactccgcct cgtccccggg
61 gctcgggcag ccgagccatg gcggggaact gtggggcccg cggcgcgctg tcggcgcaca
121 cgctgctgtt cgacctgccg cccgcgctgc tcggagagct ctgcgctgtt ctggacagct
181 gcgacggcgc gctgggctgg cgcggcctgg cagagagact ttcaagcagc tggctggatg
241 ttcgtcatat tgaaaagtat gtagaccaag gtaaaagtgg aacaagagaa ttactttggt
301 cctgggcaca gaaaaacaag accatcggtg accttttaca ggtcctccag gagatgggac
361 atcgtcgagc tattcattta attacaaact atggagcagt gttgagtcct tcagagaaga
421 gttatcagga aggtggattt ccaaatatat tattcaagga aacagccaat gtcaccgtgg
481 ataatgttct tattcctgaa cataatgaaa aaggagtact gcttaaatct tccatcagct
541 ttcaaaatat catagaagga actagaaatt tccacaaaga cttcctaatt ggagaaggag
601 agatttttga ggtatacaga gtggagattc aaaacctaac atatgctgtc aaattattta
661 aacaggagaa aaaaatgcag tgtaagaagc attggaagag gtttttatct gagcttgaag
721 ttttactact gtttcatcac ccaaacatac tagagttggc tgcatatttt acagagactg
781 agaagttctg tctgatttat ccatacatga gaaatggaac actttttgac agattgcagt
841 gtgtaggtga cacggcccca ctcccttggc acattcgaat cggtatatta ataggaatat
901 ccaaagccat tcactacctg cacaacgttc aaccatgctc ggtcatctgt ggcagtatat
961 caagtgcaaa catccttttg gatgatcagt ttcaacccaa actaactgat tttgccatgg
1021 cacacttccg gtcccaccta gaacatcaga gttgtaccat aaatatgacc agcagcagca
1081 gtaaacatct gtggtacatg ccagaagagt acatcagaca ggggaaactt tccattaaaa
1141 cagatgtcta cagctttgga attgtaataa tggaagttct aacaggatgt agagtagtgt
1201 tagatgatcc aaaacatatc cagctgcggg atctccttag agaattgatg gagaagagag
1261 gcctggattc atgtctctca tttctagata agaaagtgcc tccctgccct cggaatttct
1321 ctgccaagct cttctgtttg gcaggccggt gtgctgcaac gcgggcaaag ttaagaccat
1381 caatggatga agttttaaat actcttgaaa gtactcaagc cagcttgtat tttgctgaag
1441 atcctcccac atcactaaag tccttcaggt gtccttctcc tctattcctg gagaatgtac
1501 caagtattcc agtggaagat gatgaaagcc agaataacaa tttactacct tctgatgaag
1561 gcctgaggat agacagaatg actcagaaaa ctccttttga atgcagccag tctgaggtta
1621 tgtttctgag cttggacaaa aagccagaga gcaagagaaa tgaggaagct tgcaacatgc
1681 ccagttcttc ttgtgaagaa agttggttcc caaagtatat agttccatcc caggacttaa
1741 ggccctataa ggtaaatata gatccttctt cagaagctcc agggcattct tgcaggagca
1801 ggccagtgga gagcagctgt tcctccaaat tttcctggga tgaatatgaa cagtacaaaa
1861 aagaataaat tctaccagaa gataaagaaa aaagcaagta ttgcataggc acctgagcat
1921 aggtatgacc ttgggaagac attggctcca taagcaatgc caagagaatg atcaatagtg
1981 agtttgggtg atgcagataa acaatctgga taattccatt tctttttccc aaaccctcaa
2041 acagagtgcc ttaaaaaatt gttttatcag gataattgtc tcatgaccaa atccacgctc
2101 aattagagcc attcaaaatt ccttaagatc atgggttctg acttcagcca aacaaaacaa
2161 tcaaaaccta ccaaaaaggg actggattgt aatgtcctct ccatcatcct cagtgtgagt
2221 cctcagagcc tccatctgcc aagaacattc agttggattc catcgtttgg tttagcttgc
2281 ttgcacgggt tgtaggaaat gtctaatttg taaatgttaa tagatacctt tggaaagaaa
2341 aaaaaaaaaa aaa
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