LOCUS BC056146 2967 bp mRNA linear HUM 15-JUL-2006 DEFINITION Homo sapiens hook homolog 3 (Drosophila), mRNA (cDNA clone MGC:64918 IMAGE:5106726), complete cds. ACCESSION BC056146 VERSION BC056146.1 KEYWORDS MGC. SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. REFERENCE 1 (bases 1 to 2967) AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A. CONSRTM Mammalian Gene Collection Program Team TITLE Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002) PUBMED 12477932 REFERENCE 2 (bases 1 to 2967) CONSRTM NIH MGC Project TITLE Direct Submission JOURNAL Submitted (04-AUG-2003) National Institutes of Health, Mammalian Gene Collection (MGC), Bethesda, MD 20892-2590, USA REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov COMMENT Contact: MGC help desk Email: cgapbs-r@mail.nih.gov Tissue Procurement: ATCC cDNA Library Preparation: Life Technologies, Inc. cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL) DNA Sequencing by: Genome Sequence Centre, BC Cancer Agency, Vancouver, BC, Canada info@bcgsc.bc.ca Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao, Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang, Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra. Clone distribution: MGC clone distribution information can be found through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov Series: IRAK Plate: 119 Row: c Column: 5 This clone was selected for full length sequencing because it passed the following selection criteria: matched mRNA gi: 33356164. FEATURES Location/Qualifiers source 1..2967 /db_xref="H-InvDB:HIT000054129" /organism="Homo sapiens" /mol_type="mRNA" /db_xref="taxon:9606" /clone="MGC:64918 IMAGE:5106726" /tissue_type="Cervix, carcinoma" /clone_lib="NIH_MGC_12" /lab_host="DH10B" /note="Vector: pCMV-SPORT6" gene 1..2967 /gene="HOOK3" /gene_synonym="HK3" /db_xref="GeneID:84376" /db_xref="HGNC:HGNC:23576" /db_xref="MIM:607825" CDS 124..2280 /gene="HOOK3" /gene_synonym="HK3" /codon_start=1 /product="hook homolog 3 (Drosophila)" /protein_id="AAH56146.1" /db_xref="GeneID:84376" /db_xref="HGNC:HGNC:23576" /db_xref="MIM:607825" /translation="MFSVESLERAELCESLLTWIQTFNVDAPCQTVEDLTNGVVMAQV LQKIDPAYFDENWLNRIKTEVGDNWRLKISNLKKILKGILDYNHEILGQQINDFTLPD VNLIGEHSDAAELGRMLQLILGCAVNCEQKQEYIQAIMMMEESVQHVVMTAIQELMSK ESPVSAGNDAYVDLDRQLKKTTEELNEALSAKEEIAQRCHELDMQVAALQEEKSSLLA ENQVLMERLNQSDSIEDPNSPAGRRHLQLQTQLEQLQEETFRLEAAKDDYRIRCEELE KEISELRQQNDELTTLADEAQSLKDEIDVLRHSSDKVSKLEGQVESYKKKLEDLGDLR RQVKLLEEKNTMYMQNTVSLEEELRKANAARSQLETYKRQVVELQNRLSEESKKADKL DFEYKRLKEKVDSLQKEKDRLRTERDSLKETIEELRCVQAQEGQLTTQGLMPLGSQES SDSLAAEIVTPEIREKLIRLQHENKMLKLNQEGSDNEKIALLQSLLDDANLRKNELET ENRLVNQRLLEVQSQVEELQKSLQDQGSKAEDSVLLKKKLEEHLEKLHEANNELQKKR AIIEDLEPRFNNSSLKIEELQEALRKKEEEMKQMEERYKKYLEKAKSVIRTLDPKQNQ GAAPEIQALKNQLQERDRLFHSLEKEYEKTKSQREMEEKYIVSAWYNMGMTLHKKAAE DRLASTGSGQSFLARQRQATSSRRSYPGHVQPATAR" BASE COUNT 1027 a 518 c 671 g 751 t ORIGIN 1 cggccggatc cgaggagcag gcgggcctga ggccgagtca gctgcgcggg cccccggatc 61 ccccgacaga gcggcggcgg tgtctggcca ggcggtaggc gctgcctggc cgcggcgggg 121 aagatgttca gcgtagagtc gctggagcgg gcggagctgt gcgagagcct cctcacttgg 181 atccagacat ttaatgtgga tgcaccatgc cagaccgtgg aagatttaac gaatggggtt 241 gtgatggccc aggttcttca aaagatagat cctgcatatt ttgatgaaaa ttggctaaac 301 agaatcaaaa ctgaagtagg agataattgg aggctaaaga taagcaattt aaagaaaatt 361 ttaaaaggaa tcttggatta taatcatgag attttaggac agcaaattaa tgactttacc 421 cttcctgatg tgaaccttat tggggagcat tctgatgcag cagagcttgg aaggatgctt 481 cagctcatct taggctgtgc tgtgaactgt gaacagaagc aagagtacat ccaagccatt 541 atgatgatgg aggaatctgt tcaacatgtt gtcatgacag ccattcaaga gctgatgagt 601 aaagaatctc ctgtctctgc tggaaatgat gcctatgttg accttgatcg tcagctgaag 661 aaaactacag aggaactaaa tgaagctttg tcagcaaagg aagaaattgc tcaaagatgc 721 catgaactgg atatgcaggt tgcagcattg caggaagaga aaagtagttt gttggcagag 781 aatcaggtat taatggaaag actcaatcaa tctgattcta tagaagaccc taacagtcca 841 gcaggaagaa ggcatttgca gctccagact caattagaac agctccaaga agaaacattc 901 agactagaag cagccaaaga tgattatcga atacgttgtg aagagttaga aaaggagatc 961 tctgaacttc ggcaacagaa tgatgaactg accactttgg cagatgaagc tcagtctctg 1021 aaagatgaga tcgacgtgct gagacattct tctgataaag tatctaaact agaaggtcaa 1081 gtagaatctt ataaaaagaa gctagaagac cttggtgatt taaggcggca ggttaaactc 1141 ttagaagaga agaataccat gtatatgcag aatactgtca gtctagagga agagttaaga 1201 aaggccaacg cagcgcgaag tcaacttgaa acctacaaga gacaggtagt agaactacaa 1261 aacagattat ccgaagaatc aaagaaagca gataaactag attttgaata taagcggcta 1321 aaagaaaaag ttgacagtct tcaaaaagaa aaggacaggc tgagaacaga aagggattct 1381 ctgaaggaaa ccattgaaga gcttcgttgt gtacaagctc aagaagggca gctcacaaca 1441 caagggttaa tgcctcttgg aagtcaggag tcttcagaca gtctagctgc agagattgtt 1501 acacctgaaa tcagggagaa acttattcgt cttcagcatg agaataagat gttaaagctt 1561 aaccaagaag gttcggacaa tgaaaaaata gccttattgc agagccttct agatgatgca 1621 aatctacgca agaatgaact ggagacagag aataggctgg tgaatcaaag acttctggaa 1681 gtacagtcac aagttgaaga attacaaaaa tctttacagg atcaaggctc aaaagcagaa 1741 gattcagtcc ttctaaaaaa gaagcttgaa gaacatctag agaagctgca tgaggccaat 1801 aatgaactac agaagaagag agccattatt gaagatctcg agccaagatt taacaacagc 1861 tccttaaaaa ttgaagaatt acaagaagct ttacgaaaga aagaggaaga aatgaagcaa 1921 atggaagaac gatacaaaaa atacttagag aaagccaaaa gtgtcatccg tactttagat 1981 cctaaacaga atcaaggagc agcaccagaa atacaagctc ttaaaaatca gctccaggaa 2041 cgagaccgac tgttccactc attagagaaa gaatatgaga aaacaaagag tcagagagag 2101 atggaagaga aatatattgt tagtgcctgg tacaatatgg gaatgaccct gcataaaaag 2161 gcagctgaag atagactggc aagcacaggc tcagggcagt catttctggc gaggcagagg 2221 caagcgacca gcagcagaag atcataccca ggccacgtgc agccggccac agcaaggtag 2281 agaagttgtg ccgctcaatc acagacacct gcacccacaa catacttctg ttacacacaa 2341 gaacatttca ggaaactcag ccagcttatt ttttgtttct cttctatgtc aatacttagt 2401 gtttctcatt ttgaggactt tttctctctc ctgtatcttt gttttagttt ctttggtttt 2461 tattttgtag tcctttcagt tatttttaat gtgccaaaaa tttgtacatg ttcaattaaa 2521 aatgttgtat aatagtgtaa tacttttctt tgtatgaaaa tgtcctcttc ttcaaaggta 2581 taggctttgt aatgaattag attttctgcc aataattgat atacaattta tattctttat 2641 tgtgcctgtg tgttaccatg ctaagaatgt ctttgtttaa agggaattaa tctttttatg 2701 atgtattaat ctgtgttttc aattgttttc caagtacagt tcaaataact tgcatattta 2761 ctatacaaaa tggttgacaa gtgttctttt tgcaaagact tgaatacatt ggcagaggtg 2821 ctaatcacat cttccctaag gcacctggaa gaattatttg aggaaaaaat gagttttcac 2881 attgttttat aggaaattaa atttgtccaa agatttggag actattttta aaacataaat 2941 acataaaatt tcaaaaaaaa aaaaaaa //