LOCUS BC056143 3743 bp mRNA linear HUM 18-JAN-2007
DEFINITION Homo sapiens DIS3 mitotic control homolog (S. cerevisiae), mRNA
(cDNA clone MGC:64876 IMAGE:5505671), complete cds.
ACCESSION BC056143
VERSION BC056143.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3743)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3743)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (04-AUG-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Lou Staudt
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 119 Row: f Column: 4
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 19923415.
FEATURES Location/Qualifiers
source 1..3743
/db_xref="H-InvDB:HIT000054128"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:64876 IMAGE:5505671"
/tissue_type="Lymph, lymphoma"
/clone_lib="NIH_MGC_85"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..3743
/gene="DIS3"
/gene_synonym="bA555G22.1"
/gene_synonym="dis3p"
/gene_synonym="RP11-342J4.3"
/gene_synonym="RRP44"
/db_xref="GeneID:22894"
/db_xref="HGNC:HGNC:20604"
/db_xref="MIM:607533"
CDS 102..2978
/gene="DIS3"
/gene_synonym="bA555G22.1"
/gene_synonym="dis3p"
/gene_synonym="RP11-342J4.3"
/gene_synonym="RRP44"
/codon_start=1
/product="DIS3 mitotic control homolog (S. cerevisiae)"
/protein_id="AAH56143.1"
/db_xref="GeneID:22894"
/db_xref="HGNC:HGNC:20604"
/db_xref="MIM:607533"
/translation="MLKSKTFLKKTRAGGVMKIVREHYLRDDIGCGAPGCAACGGAHE
GPALEPQPQDPASSVCPQPHYLLPDTNVLLHQIDVLEDPAIRNVIVLQTVLQEVRNRS
APVYKRIRDVTNNQEKHFYTFTNEHHRETYVEQEQGENANDRNDRAIRVAAKWYNEHL
KKMSADNQLQVIFITNDRRNKEKAIEEGIPAFTCEEYVKSLTANPELIDRLACLSEEG
NEIESGKIIFSEHLPLSKLQQGIKSGTYLQGTFRASRENYLEATVWIHGDNEENKEII
LQGLKHLNRAVHEDIVAVELLPKSQWVAPSSVVLHDEGQNEEDVEKEEERERMLKTAV
SEKMLKPTGRVVGIIKRNWRPYCGMLSKSDIKESRRHLFTPADKRIPRIRIETRQAST
LEGRRIIVAIDGWPRNSRYPNGHFVRNLGDVGEKETETEVLLLEHDVPHQPFSQAVLS
FLPKMPWSITEKDMKNREDLRHLCICSVDPPGCTDIDDALHCRELENGNLEVGVHIAD
VSHFIRPGNALDQESARRGTTVYLCEKRIDMVPELLSSNLCSLKCDVDRLAFSCIWEM
NHNAEILKTKFTKSVINSKASLTYAEAQLRIDSANMNDDITTSLRGLNKLAKILKKRR
IEKGALTLSSPEVRFHMDSETHDPIDLQTKELRETNSMVEEFMLLANISVAKKIHEEF
SEHALLRKHPAPPPSNYEILVKAARSRNLEIKTDTAKSLAESLDQAESPTFPYLNTLL
RILATRCMMQAVYFCSGMDNDFHHYGLASPIYTHFTSPIRRYADVIVHRLLAVAIGAD
CTYPELTDKHKLADICKNLNFRHKMAQYAQRASVAFHTQLFFKSKGIVSEEAYILFVR
KNAIVVLIPKYGLEGTVFFEEKDKPNPQLIYDDEIPSLKIEDTVFHVFDKVKVKIMLD
SSNLQHQKIRMSLVEPQIPGISIPTDTSNMDLNGPKKKKMKLGK"
BASE COUNT 1233 a 675 c 808 g 1027 t
ORIGIN
1 ggaatggaaa gggaagaacc tccggggtta ggcgtattct agattgacgc cttttgctgg
61 aagagcgctg ctggggttag gattctgcgc ggcgaggcaa gatgctcaag tccaagacgt
121 tcttaaaaaa gacccgggcg ggcggcgtga tgaagatcgt gcgcgagcac tacctgcgag
181 acgacatcgg ctgcggtgcg cccgggtgcg cagcgtgtgg aggggcgcac gaggggccgg
241 ccctggagcc gcagccccag gacccggcga gcagcgtctg cccgcaaccg cactacttgc
301 tgcccgacac taatgtgtta ctgcaccaga ttgatgttct tgaggaccct gccatcagga
361 atgtaattgt gctacaaaca gttcttcaag aagtgagaaa tcgcagtgcc cccgtatata
421 aacgcatccg agatgtgact aataaccaag agaagcattt ctatactttc actaatgagc
481 accatagaga aacctatgta gaacaagaac agggagaaaa tgctaatgac aggaatgata
541 gagcgattcg agtagcagca aaatggtaca atgaacattt gaaaaaaatg tcagcagaca
601 accagctgca agttatcttc ataacaaatg acaggagaaa caaagagaaa gccatagaag
661 aaggaatacc agctttcact tgtgaagaat atgtaaagag cctaactgct aaccccgaac
721 tcatagatcg tcttgcttgt ttgtctgaag aagggaatga aatagaaagt ggaaaaataa
781 tattttcaga gcatcttccc ttaagtaagc tacagcaagg cataaaatct ggtacatacc
841 ttcaaggaac atttagagct agcagggaaa attacttgga agctacagta tggattcatg
901 gcgacaatga agaaaataaa gagataatct tacagggact taaacattta aacagagctg
961 ttcacgaaga tattgtggct gtggagcttc tccccaagag tcagtgggta gcaccatctt
1021 ctgtggtttt acatgatgaa ggtcaaaatg aagaagatgt ggagaaagaa gaagagagag
1081 aacgaatgct taagactgct gtaagcgaga aaatgttgaa gcctacaggt agagttgtag
1141 gaataataaa aaggaattgg agaccatatt gtggcatgct ttccaagtct gacattaagg
1201 agtcaagaag acatctcttt acacctgctg ataagagaat ccctcgaatt cgcatagaaa
1261 ccagacaggc ttccacatta gaaggacgga gaattattgt tgctattgat ggttggccca
1321 gaaattccag atatccaaat ggacactttg tgagaaattt aggtgatgtt ggagagaaag
1381 agactgaaac agaagttttg ttacttgaac acgatgttcc ccatcagcct ttttcacagg
1441 ctgttcttag ttttctgcca aagatgccct ggagcattac tgaaaaggac atgaaaaacc
1501 gagaagacct gaggcatctg tgtatttgta gtgtagaccc accaggatgt actgatatag
1561 acgatgctct acattgtcga gaactcgaaa atggaaattt ggaggttggt gttcatattg
1621 ctgatgtgag ccattttatt aggccaggaa atgccttgga tcaagaatca gccagaagag
1681 gaacaactgt gtatctttgt gaaaagagga ttgacatggt tccagagttg cttagctcta
1741 acttgtgttc cttaaaatgt gacgtggaca ggctggcatt ttcatgtatt tgggaaatga
1801 atcacaatgc tgaaatctta aaaacgaagt ttaccaaaag tgttattaat tcaaaggcat
1861 ctctgacata tgctgaagct cagttgagaa ttgattcagc aaacatgaat gatgatatta
1921 ccactagtct ccgtggactg aataaactag ccaaaattct gaagaaaaga aggattgaaa
1981 aaggggcttt gactctatcc tctcctgaag ttcgattcca catggacagt gaaactcacg
2041 atcctataga tctgcagacc aaggaactta gggaaacaaa ttccatggtt gaagaattta
2101 tgttacttgc caatatttct gttgcaaaaa aaattcatga ggaattttct gaacatgctc
2161 tgcttcgaaa acatcctgct ccacctccat caaattatga aattcttgtt aaggcagcca
2221 ggtcaaggaa tttggaaatt aagactgata cagccaagtc tttggctgag tctttggatc
2281 aggccgaatc tcctactttt ccatatctaa acactctgtt gagaatatta gccactcgct
2341 gtatgatgca agctgtgtac ttctgttctg gaatggataa tgattttcat cactatggct
2401 tagcgtctcc aatatacaca cattttactt cacccattag aagatacgca gatgtcattg
2461 ttcatcggct tttggctgtg gctattgggg ctgactgtac ttatccagag ttgacagaca
2521 aacacaagct tgcagatata tgtaaaaatc taaatttccg gcacaaaatg gctcaatatg
2581 cccaacgtgc atcagtggct tttcataccc agttattctt caaaagcaaa ggaatagtaa
2641 gtgaagaagc ctatatttta tttgtaagaa agaatgccat tgtggtatta attccaaagt
2701 atggtttaga agggacagtc ttttttgaag aaaaggacaa accaaaccca cagcttattt
2761 atgatgatga gataccctca cttaaaatag aagatacagt gttccatgta tttgataaag
2821 ttaaagtgaa aatcatgtta gactcatcta atcttcaaca tcagaagatc cgaatgtccc
2881 tggtagaacc acagatacca ggaataagca ttcctactga tacttcaaac atggacctta
2941 atggaccaaa gaaaaagaag atgaagcttg gaaaatagct atattcaaca aaaatcttca
3001 aagactggtt tcttttttaa aagaaaaaac ttgaaagaac acttctaagc ctaagtgtgt
3061 gatacagttt gttactttta agtacatttt aataatttca gacatctgca tttttattga
3121 acagttgact gtatctgacc catcatacta ctatacttct gggttgaaca gaattattta
3181 tgcagaataa ttcaattgaa tatccatcac ttaaatacag tgacaggaca gcaacttcag
3241 ggatctgtaa agatcattta aatggagtgc tcatctcatt gaggagcaga ttaattttgc
3301 gtaagtactt tgattattta atatttgtaa gaaaaaactt tcattttcct acagaggaaa
3361 atagaacaat tttagaagca aggaacaatc tcttttctaa gtcttggaag ctgtcagtgt
3421 tgaggatgta atctcctttg ccatctttaa ttcacctaac ttacactagg tgttctctta
3481 ctgtctttaa aagcttcctg tattttatta gtggtccttg aaaaactgtg aatgtttggg
3541 aattggtaga aaggcaaaaa gtaggatatt ttgacctgac tggaaagatg gttgtgtttt
3601 tattgccagg taataagtgt gatcattgtt gaacttcagc tccagtgtct ctccagaata
3661 agacattggc attcaaatgt ctatatcttg ttacttacaa aataaaaaac agataattag
3721 tggcttttaa aaaaaaaaaa aaa
//