LOCUS BC054511 5030 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens deleted in liver cancer 1, mRNA (cDNA clone MGC:60210
IMAGE:5240161), complete cds.
ACCESSION BC054511
VERSION BC054511.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5030)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 5030)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (01-JUL-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 110 Row: d Column: 18
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 33188432.
FEATURES Location/Qualifiers
source 1..5030
/db_xref="H-InvDB:HIT000054084"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:60210 IMAGE:5240161"
/tissue_type="Brain, fetal, whole pooled"
/clone_lib="NIH_MGC_121"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..5030
/gene="DLC1"
/gene_synonym="ARHGAP7"
/gene_synonym="FLJ21120"
/gene_synonym="HP"
/gene_synonym="p122-RhoGAP"
/gene_synonym="STARD12"
/db_xref="GeneID:10395"
/db_xref="HGNC:HGNC:2897"
/db_xref="MIM:604258"
CDS 200..4786
/gene="DLC1"
/gene_synonym="ARHGAP7"
/gene_synonym="FLJ21120"
/gene_synonym="HP"
/gene_synonym="p122-RhoGAP"
/gene_synonym="STARD12"
/codon_start=1
/product="deleted in liver cancer 1"
/protein_id="AAH54511.1"
/db_xref="GeneID:10395"
/db_xref="HGNC:HGNC:2897"
/db_xref="MIM:604258"
/translation="MSVAIRKRSWEEHVTHWMGQPFNSDDRNTACHHGLVADSLQASM
EKDATLNVDRKEKCVSLPDCCHGSELRDFPGRPMGHLSKDVDENDSHEGEDQFLSLEA
STETLVHVSDEDNNADLCLTDDKQVLNTQGQKTSGQHMIQGAGSLEKALPIIQSNQVS
SNSWGIAGETELALVKESGERKVTDSISKSLELCNEISLSEIKDAPKVNAVDTLNVKD
IAPEKQLLNSAVIAQQRRKPDPPKDENERSTCNVVQDEFLDTPCTNRGLPLLKTDFGS
CLLQPPSCPNGMSAENGLEKSGFSQHQNKSPPKVKAEDGMQCLQLKETLATQEPTDNQ
VRLRKRKEIREDRDRARLDSMVLLIMKLDQLDQDIENALSTSSSPSGTPTNLRRHVPD
LESGSESGADTISVNQTRVNLSSDTESTDLPSSTPVANSGTKPKTTAIQGISEKEKAE
IEAKEACDWLRATGFPQYAQLYEDFLFPIDISLVKREHDFLDRDAIEALCRRLNTLNK
CAVMKLEISPHRKRSDDSDEDEPCAISGKWTFQRDSKRWSRLEEFDVFSPKQDLVPGS
PDDSHPKDGPSPGGTLMDLSERQEVSSVRSLSSTGSLPSHAPPSEDAATPRTNSVISV
CSSSNLAGNDDSFGSLPSPKELSSFSFSMKGHEKTAKSKTRSLLKRMESLKLKSSHHS
KHKAPSKLGLIISGPILQEGMDEEKLKQLNCVEISALNGNRINVPMVRKRSVSNSTQT
SSSSSQSETSSAVSTPSPVTRTRSLSACNKRVGMYLEGFDPFNQSTFNNVVEQNFKNR
ESYPEDTVFYIPEDHKPGTFPKALTNGSFSPSGNNGSVNWRTGSFHGPGHISLRRENS
SDSPKELKRRNSSSSMSSRLSIYDNVPGSILYSSSGDLADLENEDIFPELDDILYHVK
GMQRIVNQWSEKFSDEGDSDSALDSVSPCPSSPKQIHLDVDNDRTTPSDLDSTGNSLN
EPEEPSEIPERRDSGVGASLTRSNRHRLRWHSFQSSHRPSLNSVSLQINCQSVAQMNL
LQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYKDRSVFGVPLTVNVQRTG
QPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAIDCVNYEGQSAYDV
ADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTL
LYFLSDVTAAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRKQSLGKPDQKD
LNENLAATQGLAHMIAECKKLFQVPEEMSRCRNSYTEQELKPLTLEALGHLGNDDSAD
YQHFLQDCVDGLFKEVKEKFKGWVSYSTSEQAELSYKKVSEGPPLRLWRSVIEVPAVP
EEILKRLLKEQHLWDVDLLDSKVIEILDSQTEIYQYVQNSMAPHPARDYVVLRTWRTN
LPKGACALLLTSVDHDRAPVVGVRVNVLLSRYLIEPCGPGKSKLTYMCRVDLRGHMPE
WYTKSFGHLCAAEVVKIRDSFSNQNTETKDTKSR"
BASE COUNT 1436 a 1267 c 1229 g 1098 t
ORIGIN
1 cggggacgga cttctttcct agcctgagtg ttgagcagtg tcatgccttg gcgtttcagc
61 tcctcgttgt ctaggtggtg aaatgacaga actcattcgc ttctttgatt ggtgattttg
121 aaataatctt tcatcaagtt ccatctcctt taccctcata tggaatatat ctctctgtct
181 gttgttaaac tacgatgaca tgtctgtagc tatcagaaag agaagctggg aagaacatgt
241 gacccactgg atgggacagc cttttaattc tgatgatcgt aacacagcat gtcatcatgg
301 actagtagct gacagcttgc aggcaagtat ggaaaaagat gcaactctaa atgtggaccg
361 caaagagaag tgtgtttcac tacctgactg ctgtcatgga tcagagctga gagattttcc
421 tgggaggcca atgggtcatc tttcaaagga tgtggacgaa aatgacagcc atgaaggtga
481 agatcagttt ctttctctgg aagccagcac agaaacacta gtgcatgttt ctgatgagga
541 taacaatgct gatttatgcc ttacagatga taaacaggtt ttaaataccc aagggcagaa
601 aacatcaggc caacatatga tccaaggagc aggctcctta gaaaaggcac tgcccatcat
661 acaaagtaac caagtttctt ctaactcctg gggaatagct ggtgaaactg aattagcact
721 ggtaaaagaa agtggggaga gaaaagttac tgactctata agtaaaagcc tggagctttg
781 caatgaaata agcttaagtg aaataaaaga tgcacccaaa gtaaatgcag tggatacttt
841 gaacgtgaaa gatattgcac ctgagaaaca attgcttaac tctgctgtaa ttgctcagca
901 acgaaggaaa cctgaccccc ctaaagatga aaatgaaaga agcacctgca atgtagtaca
961 agatgagttc ttggatactc cttgcacaaa cagaggactg ccattattaa aaacagattt
1021 tggaagctgc cttctgcagc ctccttcctg ccccaatgga atgtcagctg aaaatggcct
1081 ggagaagagt ggtttttcac aacatcaaaa caaaagtcca ccaaaggtca aggcagaaga
1141 tggcatgcag tgtttacaat taaaggagac cctggccacc caggaaccca cagataacca
1201 agtcagactt cgtaagagaa aggaaataag agaagatcga gatagggcgc ggctggactc
1261 catggtgctg ctgattatga aactggacca gcttgatcag gacatagaaa atgccctcag
1321 caccagctcc tctccatcag gcacaccaac aaacctgcgg cggcacgttc ctgatctgga
1381 atcaggatct gaaagtggag cagataccat ttcagtaaat cagacacgag taaatttgtc
1441 ttctgacact gagtccacgg acctcccatc ttccactcca gtagccaatt ctggaaccaa
1501 acccaagact acggctattc aaggtatttc agagaaggaa aaggctgaaa ttgaagccaa
1561 ggaagcttgt gattggctac gggcaactgg tttcccccag tatgcacagc tttatgaaga
1621 tttcctgttc cccatcgata tttccttggt caagagagag catgattttt tggacagaga
1681 tgccattgag gctctatgca ggcgtctaaa tactttaaac aaatgtgcgg tgatgaagct
1741 agaaattagt cctcatcgga aacgaagtga cgattcagac gaggatgagc cttgtgccat
1801 cagtggcaaa tggactttcc aaagggacag caagaggtgg tcccggcttg aagagtttga
1861 tgtcttttct ccaaaacaag acctggtccc tgggtcccca gacgactccc acccgaagga
1921 cggccccagc cccggaggca cgctgatgga cctcagcgag cgccaggagg tgtcttccgt
1981 ccgcagcctc agcagcactg gcagcctccc cagccacgct ccccccagcg aggatgctgc
2041 caccccccgg actaactccg tcatcagcgt ttgctcctcc agcaacttgg caggcaatga
2101 cgactctttc ggcagcctgc cctctcccaa ggaactgtcc agcttcagct tcagcatgaa
2161 aggccacgaa aaaactgcca agtccaagac gcgcagtctg ctgaaacgga tggagagcct
2221 gaagctcaag agctcccatc acagcaagca caaagcgccc tcaaagctgg ggttgatcat
2281 cagcgggccc atcttgcaag aggggatgga tgaggagaag ctgaagcagc tcaactgcgt
2341 ggagatctcc gccctcaatg gcaaccgcat caacgtcccc atggtacgaa agaggagcgt
2401 ttccaactcc acgcagacca gcagcagcag cagccagtcg gagaccagca gcgcggtcag
2461 cacgcccagc cctgttacga ggacccggag cctcagtgcg tgcaacaagc gggtgggcat
2521 gtacttagag ggcttcgatc ctttcaatca gtcaacattt aacaacgtgg tggagcagaa
2581 ctttaagaac cgcgagagct acccggagga cacggtgttc tacatccctg aagatcacaa
2641 gcctggcact ttccccaaag ctctcaccaa tggcagtttc tccccctcgg ggaataacgg
2701 ctctgtgaac tggaggacgg gaagcttcca cggccctggc cacatcagcc tcaggaggga
2761 aaacagtagc gacagcccca aggaactgaa gagacgcaat tcttccagct ccatgagcag
2821 ccgcctgagc atctacgaca acgtgccggg ctccatcctc tactccagtt caggggacct
2881 ggcggatctg gagaacgagg acatcttccc cgagctggac gacatcctct accacgtgaa
2941 ggggatgcag cggatagtca atcagtggtc ggagaagttt tctgatgagg gagattcgga
3001 ctcagccctg gactcggtct ctccctgccc gtcctctcca aaacagatac acctggatgt
3061 ggacaacgac cgaaccacac ccagcgacct ggacagcaca ggcaactccc tgaatgaacc
3121 ggaagagccc tccgagatcc cggaaagaag ggattctggg gttggggctt ccctaaccag
3181 gtccaacagg caccgactga gatggcacag tttccagagc tcacatcggc caagcctcaa
3241 ctctgtatca ctacagatta actgccagtc tgtggcccag atgaacctgc tgcagaaata
3301 ctcactccta aagctaacgg ccctgctgga gaaatacaca ccttctaaca agcatggttt
3361 tagctgggcc gtgcccaagt tcatgaagag gatcaaggtt ccagactaca aggaccggag
3421 tgtgtttggg gtcccactga cggtcaacgt gcagcgcaca ggacaaccgt tgcctcagag
3481 catccagcag gccatgcgat acctccggaa ccattgtttg gatcaggttg ggctcttcag
3541 aaaatcgggg gtcaagtccc ggattcaggc tctgcgccag atgaatgaag gtgccataga
3601 ctgtgtcaac tacgaaggac agtctgctta tgacgtggca gacatgctga agcagtattt
3661 tcgagatctt cctgagccac taatgacgaa caaactctcg gaaacctttc tacagatcta
3721 ccaatatgtg cccaaggacc agcgcctgca ggccatcaag gctgccatca tgctgctgcc
3781 tgacgagaac cgggaggttc tgcagaccct gctttatttc ctgagcgatg tcacagcagc
3841 cgtaaaagaa aaccagatga ccccaaccaa cctggccgtg tgcttagcgc cttccctctt
3901 ccatctcaac accctgaaga gagagaattc ctctcccagg gtaatgcaaa gaaaacaaag
3961 tttgggcaaa ccagatcaga aagatttgaa tgaaaaccta gctgccactc aagggctggc
4021 ccatatgatc gccgagtgca agaagctttt ccaggttccc gaggaaatga gccgatgtcg
4081 taattcctat accgaacaag agctgaagcc cctcactctg gaagcactcg ggcacctggg
4141 taatgatgac tcagctgact accaacactt cctccaggac tgtgtggatg gcctgtttaa
4201 agaagtcaaa gagaagttta aaggctgggt cagctactcc acttcggagc aggctgagct
4261 gtcctataag aaggtgagcg aaggaccccc tctgaggctt tggaggtcag tcattgaagt
4321 ccctgctgtg ccagaggaaa tcttaaagcg cctacttaaa gaacagcacc tctgggatgt
4381 agacctgttg gattcaaaag tgatcgaaat tctggacagc caaactgaaa tttaccagta
4441 tgtccaaaac agtatggcac ctcatcctgc tcgagactac gttgttttaa gaacctggag
4501 gactaattta cccaaaggag cctgtgccct tttactaacc tctgtggatc acgatcgcgc
4561 acctgtggtg ggtgtgaggg ttaatgtgct cttgtccagg tatttgattg aaccctgtgg
4621 gccaggaaaa tccaaactca cctacatgtg cagagttgac ttaaggggcc acatgccaga
4681 atggtacaca aaatcttttg gacatttgtg tgcagctgaa gttgtaaaga tccgggattc
4741 cttcagtaac cagaacactg aaaccaaaga caccaaatct aggtgatcac tgaagcaacg
4801 caaccgcttc caccaccatg gtgtttgttt ctagaacttt tgccagtcct tgaagaatgg
4861 gttctgtgtc taatcctgaa acaaagaaaa ctacaagctg gagtgtagga attgactata
4921 gcaatttgat acatttttaa agctgcttcc tgtttgttga gggtctgtat tcatagacct
4981 tgactggaat atgtaagact gtgcaaaaaa aaaaaaaaaa aaaaaaaaaa
//