LOCUS BC054510 2638 bp mRNA linear HUM 08-OCT-2003
DEFINITION Homo sapiens histamine receptor H2, mRNA (cDNA clone MGC:60198
IMAGE:6146988), complete cds.
ACCESSION BC054510
VERSION BC054510.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2638)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2638)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (01-JUL-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Sep 16, 2003 this sequence version replaced BC054510.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC/DCTD/DTP
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 110 Row: k Column: 5
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 13435404.
FEATURES Location/Qualifiers
source 1..2638
/db_xref="H-InvDB:HIT000054083"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:60198 IMAGE:6146988"
/tissue_type="Skin, melanotic melanoma."
/clone_lib="NIH_MGC_72"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2638
/gene="HRH2"
/gene_synonym="H2R"
/db_xref="GeneID:3274"
/db_xref="MIM:142703"
CDS 659..1852
/gene="HRH2"
/gene_synonym="H2R"
/codon_start=1
/product="HRH2 protein"
/protein_id="AAH54510.1"
/db_xref="GeneID:3274"
/db_xref="MIM:142703"
/translation="MAPNGTASSFCLDSTACKITITVVLAVLILITVAGNVVVCLAVG
LNRRLRNLTNCFIVSLAITDLLLGLLVLPFSAIYQLSCKWSFGKVFCNIYTSLDVMLC
TASILNLFMISLDRYCAVMDPLRYPVLVTPVRVAISLVLIWVISITLSFLSIHLGWNS
RNETSKGNHTTSKCKVQVNEVYGLVDGLVTFYLPLLIMCITYYRIFKVARDQAKRINH
ISSWKAATIREHKATVTLAAVMGAFIICWFPYFTAFVYRGLRGDDAINEVLEAIVLWL
GYANSALNPILYAALNRDFRTGYQQLFCCRLANRNSHKTSLRSNASQLSRTQSREPRQ
QEEKPLKLQVWSGTEVTAPQGATDRPWLCLPECWSVELTHSFIHLFIHSFANIHPIPT
TCQEL"
misc_feature 761..1522
/gene="HRH2"
/gene_synonym="H2R"
/note="7tm_1; Region: 7 transmembrane receptor (rhodopsin
family)"
/db_xref="CDD:pfam00001"
BASE COUNT 648 a 777 c 638 g 575 t
ORIGIN
1 cggacgcgtg ggggcgcggg gcgcaggccg tgcgcgcgcc gcccgctgca tccctgcccg
61 gagcgcagcc ggcgcgggcg cgggaccgag gcgaaccggg tgcggagcca atacccgcgg
121 cagcagcacc agctcctgcc ctccactgac tccagagagg gagatcccca gtacttgact
181 ccatcacgca gatgggagca ggcaccagct atggagaggg atacagctgc gtctccacat
241 gacccatcct gcatgacacc aaagccaccg ccagacagtg cctcggattc tatgcaaaac
301 ctgggaagcg gagacctacc ccagccccgg gaggaagcta gctcttcagg ggaccgtctg
361 aggactggag tttgatccat gaacctggct tcgaggcctt gcttttctct cttcttcatt
421 catattcatt cccaacacct tagaaggtgt tgcttaattt atttctagaa aagcagccca
481 gagtcagtca ttgaagcctt ccccaccccc tggccaaaaa aaaaaaaaaa aaaaaaactg
541 gacacatttt ggatctgttg ggagcttgga gtccagtggt tggcatagtt gtcacattgg
601 gagcagagaa gaagcaacca ggggccctga tcaggggact gagccgtaga gtcccaggat
661 ggcacccaat ggcacagcct cttccttttg cctggactct accgcatgca agatcaccat
721 caccgtggtc cttgcggtcc tcatcctcat caccgttgct ggcaatgtgg tcgtctgtct
781 ggccgtgggc ttgaaccgcc ggctccgcaa cctgaccaat tgtttcatcg tgtccttggc
841 tatcactgac ctgctcctcg gcctcctggt gctgcccttc tctgccatct accagctgtc
901 ctgcaagtgg agctttggca aggtcttctg caatatctac accagcctgg atgtgatgct
961 ctgcacagcc tccattctta acctcttcat gatcagcctc gaccggtact gcgctgtcat
1021 ggacccactg cggtaccctg tgctggtcac cccagttcgg gtcgccatct ctctggtctt
1081 aatttgggtc atctccatta ccctgtcctt tctgtctatc cacctggggt ggaacagcag
1141 gaacgagacc agcaagggca atcataccac ctctaagtgc aaagtccagg tcaatgaagt
1201 gtacgggctg gtggatgggc tggtcacctt ctacctcccg ctactgatca tgtgcatcac
1261 ctactaccgc atcttcaagg tcgcccggga tcaggccaag aggatcaatc acattagctc
1321 ctggaaggca gccaccatca gggagcacaa agccacagtg acactggccg ccgtcatggg
1381 ggccttcatc atctgctggt ttccctactt caccgcgttt gtgtaccgtg ggctgagagg
1441 ggatgatgcc atcaatgagg tgttagaagc catcgttctg tggctgggct atgccaactc
1501 agccctgaac cccatcctgt atgctgcgct gaacagagac ttccgcaccg ggtaccaaca
1561 gctcttctgc tgcaggctgg ccaaccgcaa ctcccacaaa acttctctga ggtccaacgc
1621 ctctcagctg tccaggaccc aaagccgaga acccaggcaa caggaagaga aacccctgaa
1681 gctccaggtg tggagtggga cagaagtcac ggccccccag ggagccacag acagaccatg
1741 gctttgcctt ccagaatgct ggtctgtgga actgacccat tcattcattc atttgttcat
1801 tcattcattt gcaaacattc atccaattcc caccacatgc caggaattat gatgaatact
1861 ggggatgtag aaatgagatt ttttgggttt atggtgatga agttacagaa aatcaatggc
1921 acagccctgg tctcagctct gccgtcactc aacttgtatc ttgagcaagt tcctccccat
1981 ctcaggcctc agtttcctca tcgcatagag agttggtctt ccctcaccgg gcttcctact
2041 tgccctccag agttgcctga agctcacatg agcgaaggga catgaacatg ctctgccatc
2101 tcccaatagg acataagtcc acgctggagc gctgagcatc agactcaaga aaagcttgcg
2161 tggatattgc agacccacca acaagggctc caggttctgg agttgtggag gcaaaactgc
2221 ctagtgagaa ccctacatat tccctctggt ccttgcagct gccaccccca ttcccagggg
2281 tggagtgtcc ctccatagac ttggatcctg ggccctctgc tccttcacca ctgtccatct
2341 gaagcaagcc tggttgctcc ggcactgaac tgtggcctcg ggccctggac cctgcccctc
2401 aaatccaccc tccaagtgca cacctggaaa cttccgcttc cagtcctgat gggtaaaacg
2461 cccacctacc atatccttgc gcaatctctt attcaggagg cagctggagt gcaaagctga
2521 cttagttcac aaagtataaa aaaatacagg gatgtggttc agctagaaaa aaaaaaaaaa
2581 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaa
//