LOCUS BC054489 6529 bp mRNA linear HUM 12-OCT-2006
DEFINITION Homo sapiens clathrin, heavy chain (Hc), mRNA (cDNA clone MGC:51918
IMAGE:6045540), complete cds.
ACCESSION BC054489
VERSION BC054489.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 6529)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 6529)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (01-JUL-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 98 Row: j Column: 20
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 41327727.
FEATURES Location/Qualifiers
source 1..6529
/db_xref="H-InvDB:HIT000054067"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:51918 IMAGE:6045540"
/tissue_type="Testis, embryonal carcinoma"
/clone_lib="NIH_MGC_92"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..6529
/gene="CLTC"
/gene_synonym="CHC17"
/gene_synonym="CLH-17"
/gene_synonym="Hc"
/gene_synonym="KIAA0034"
/db_xref="GeneID:1213"
/db_xref="HGNC:HGNC:2092"
/db_xref="MIM:118955"
CDS 228..5255
/gene="CLTC"
/gene_synonym="CHC17"
/gene_synonym="CLH-17"
/gene_synonym="Hc"
/gene_synonym="KIAA0034"
/codon_start=1
/product="clathrin, heavy chain (Hc)"
/protein_id="AAH54489.1"
/db_xref="GeneID:1213"
/db_xref="HGNC:HGNC:2092"
/db_xref="MIM:118955"
/translation="MAQILPIRFQEHLQLQNLGINPANIGFSTLTMESDKFICIREKV
GEQAQVVIIDMNDPSNPIRRPISADSAIMNPASKVIALKAGKTLQIFNIEMKSKMKAH
TMTDDVTFWKWISLNTVALVTDNAVYHWSMEGESQPVKMFDRHSSLAGCQIINYRTDA
KQKWLLLTGISAQQNRVVGAMQLYSVDRKVSQPIEGHAASFAQFKMEGNAEESTLFCF
AVRGQAGGKLHIIEVGTPPTGNQPFPKKAVDVFFPPEAQNDFPVAMQISEKHDVVFLI
TKYGYIHLYDLETGTCIYMNRISGETIFVTAPHEATAGIIGVNRKGQVLSVCVEEENI
IPYITNVLQNPDLALRMAVRNNLAGAEELFARKFNALFAQGNYSEAAKVAANAPKGIL
RTPDTIRRFQSVPAQPGQTSPLLQYFGILLDQGQLNKYESLELCRPVLQQGRKQLLEK
WLKEDKLECSEELGDLVKSVDPTLALSVYLRANVPNKVIQCFAETGQVQKIVLYAKKV
GYTPDWIFLLRNVMRISPDQGQQFAQMLVQDEEPLADITQIVDVFMEYNLIQQCTAFL
LDALKNNRPSEGPLQTRLLEMNLMHAPQVADAILGNQMFTHYDRAHIAQLCEKAGLLQ
RALEHFTDLYDIKRAVVHTHLLNPEWLVNYFGSLSVEDSLECLRAMLSANIRQNLQIC
VQVASKYHEQLSTQSLIELFESFKSFEGLFYFLGSIVNFSQDPDVHFKYIQAACKTGQ
IKEVERICRESNCYDPERVKNFLKEAKLTDQLPLIIVCDRFDFVHDLVLYLYRNNLQK
YIEIYVQKVNPSRLPVVIGGLLDVDCSEDVIKNLILVVRGQFSTDELVAEVEKRNRLK
LLLPWLEARIHEGCEEPATHNALAKIYIDSNNNPERFLRENPYYDSRVVGKYCEKRDP
HLACVAYERGQCDLELINVCNENSLFKSLSRYLVRRKDPELWGSVLLESNPYRRPLID
QVVQTALSETQDPEEVSVTVKAFMTADLPNELIELLEKIVLDNSVFSEHRNLQNLLIL
TAIKADRTRVMEYINRLDNYDAPDIANIAISNELFEEAFAIFRKFDVNTSAVQVLIEH
IGNLDRAYEFAERCNEPAVWSQLAKAQLQKGMVKEAIDSYIKADDPSSYMEVVQAANT
SGNWEELVKYLQMARKKARESYVETELIFALAKTNRLAELEEFINGPNNAHIQQVGDR
CYDEKMYDAAKLLYNNVSNFGRLASTLVHLGEYQAAVDGARKANSTRTWKEVCFACVD
GKEFRLAQMCGLHIVVHADELEELINYYQDRGYFEELITMLEAALGLERAHMGMFTEL
AILYSKFKPQKMREHLELFWSRVNIPKVLRAAEQAHLWAELVFLYDKYEEYDNAIITM
MNHPTDAWKEGQFKDIITKVANVELYYRAIQFYLEFKPLLLNDLLMVLSPRLDHTRAV
NYFSKVKQLPLVKPYLRSVQNHNNKSVNESLNNLFITEEDYQALRTSIDAYDNFDNIS
LAQRLEKHELIEFRRIAAYLFKGNNRWKQSVELCKKDSLYKDAMQYASESKDTELAEE
LLQWFLQEEKRECFGACLFTCYDLLRPDVVLETAWRHNIMDFAMPYFIQVMKEYLTKV
DKLDASESLRKEEEQATETQPIVYGQPQLMLTAGPSVAVPPQAPFGYGYTAPPYGQPQ
PGFGYSM"
BASE COUNT 1940 a 1308 c 1410 g 1871 t
ORIGIN
1 ggagtctgcg ctgcgcccgg ttccgccatt gcggctctcc tggcccctgg agcctccgcc
61 cccgacccga gctctttcgt ctgcctgcca gtttcctgcg tccccggaga ggatcctgct
121 gagcccagcc tcccccctcc ccttctcctc ctctcccttg gagagcccgg gcagccactg
181 ccccgcagcc ccagtgacag gaggagacca taacccccga cagcgccatg gcccagattc
241 tgccaattcg ttttcaggag catctccagc tccagaacct gggtatcaac ccagcaaaca
301 ttggcttcag taccctgact atggagtctg acaaattcat ctgcattaga gaaaaagtag
361 gagagcaggc ccaggtggta atcattgata tgaatgaccc aagtaatcca attcgaagac
421 caatttcagc agacagcgcc atcatgaatc cagctagcaa agtaattgca ctgaaagctg
481 ggaaaactct tcagattttt aacattgaaa tgaaaagtaa aatgaaggct cataccatga
541 ctgatgatgt caccttttgg aaatggatct ctttgaatac ggttgctctt gttacggata
601 atgcagttta tcactggagt atggaaggag agtctcagcc agtgaaaatg tttgatcgcc
661 attctagcct tgcagggtgc cagattatca attaccgtac agatgcaaaa caaaagtggt
721 tacttctgac tggtatatct gcacagcaaa atcgtgtggt gggagctatg cagctatatt
781 ctgtagatag gaaagtgtct cagcccattg aaggacatgc agctagcttt gcacagttta
841 agatggaagg aaatgcagaa gaatcaacgt tattttgttt tgcagttcgg ggccaagctg
901 gagggaagtt acatattatt gaagttggca caccacctac agggaaccag ccctttccaa
961 agaaggcagt ggatgtcttc tttcctccag aagcacaaaa tgattttcct gttgcaatgc
1021 agatcagtga aaagcatgat gtggtgttct tgataaccaa gtatggttat atccacctct
1081 atgatcttga gactggtacc tgcatctaca tgaatagaat cagtggagaa acaatttttg
1141 ttactgcacc tcatgaagcc acagctggaa taattggagt aaacagaaag ggacaagttc
1201 tgtcagtgtg tgtggaagaa gaaaacataa ttccttacat caccaatgtt ctacaaaatc
1261 ctgatttggc tctgagaatg gctgtacgta ataacttagc cggtgctgaa gaactctttg
1321 cccggaaatt taatgctctt tttgcccagg gaaattactc ggaggcagca aaggtggctg
1381 ctaatgcacc aaagggaatt cttcgtactc cagacactat ccgtcggttc cagagtgtcc
1441 cagcccagcc aggtcaaact tctcctctac ttcagtactt tggtatcctt ttggaccagg
1501 gacagctcaa caaatacgaa tccttagagc tttgtaggcc tgtacttcag caagggcgaa
1561 aacagctttt ggagaaatgg ttaaaagaag ataagctgga atgttctgaa gaactgggtg
1621 atcttgtgaa atctgtggac cctacattgg cacttagtgt gtacctaagg gctaacgtcc
1681 caaataaagt cattcagtgc tttgcagaaa caggtcaagt ccaaaagatt gttttatatg
1741 ctaaaaaagt tggatacact ccagattgga tatttctgct gagaaatgta atgcgaatca
1801 gtccagatca gggacagcag tttgcccaaa tgttagttca agatgaagag cctcttgctg
1861 acatcacaca gattgtagat gtctttatgg aatacaatct aattcagcag tgtactgcat
1921 tcttgcttga tgctctgaag aataatcgcc catctgaagg tcctttacag acgcggttac
1981 ttgagatgaa ccttatgcat gcgcctcaag ttgcagatgc tattctaggc aatcagatgt
2041 tcacacatta tgaccgggct catattgctc aactgtgtga aaaggctggc ctactgcagc
2101 gtgcattaga acatttcact gatttatatg atataaaacg tgcagtggtt cacacccatc
2161 ttcttaaccc tgagtggtta gtcaactact ttggttcctt atcagtagaa gactccctag
2221 aatgtctcag agccatgctg tctgccaaca tccgtcagaa tctgcagatt tgtgttcagg
2281 tggcttctaa atatcatgaa caactgtcaa ctcagtctct gattgaactt tttgaatctt
2341 tcaagagttt tgaaggtctc ttttattttc tgggatccat tgttaacttt agccaggacc
2401 cagatgtgca ctttaaatat attcaggcag cttgcaagac tgggcaaatc aaagaagtag
2461 aaagaatctg tagagaaagc aactgctacg atcctgagcg agtcaagaat tttcttaagg
2521 aagcaaaact aacagatcag ctaccactta tcattgtgtg tgatcgattt gactttgtcc
2581 atgatttggt gctctattta tatagaaata atcttcaaaa gtatatagag atatatgtac
2641 agaaggtgaa tccaagtcga cttcctgtag ttattggagg attacttgat gttgactgtt
2701 ctgaagatgt cataaaaaac ttgattcttg ttgtaagagg tcaattctct actgatgagc
2761 ttgttgctga ggttgaaaaa agaaacagat tgaaactgct tctgccttgg ctagaggcca
2821 gaattcatga gggctgtgag gagcctgcta ctcacaatgc cttagccaaa atctacatag
2881 acagtaataa caacccggag agatttcttc gtgaaaatcc ctactatgac agtcgcgttg
2941 ttggaaagta ttgtgagaag agagatccac atctggcctg tgttgcttat gaacgtggcc
3001 aatgtgatct ggaacttatt aatgtttgca atgagaattc cctcttcaaa agtctttctc
3061 gctacctggt acgtcgaaag gatccagaat tgtggggcag cgtgctgctg gaaagcaatc
3121 cttacaggag acccctaatt gaccaggttg tacaaacagc tttgtctgag actcaggacc
3181 ctgaagaagt gtcagtaact gtaaaggctt tcatgactgc agaccttcct aatgaactca
3241 ttgaactgct ggagaaaatt gtccttgata actctgtatt cagtgaacac aggaatctgc
3301 aaaacctcct tatcctcact gcaattaagg ctgaccgtac acgtgttatg gagtatatta
3361 accgcctgga taattatgat gccccagata ttgccaatat cgccatcagc aatgagctgt
3421 ttgaagaagc atttgccatt ttccggaaat ttgatgtcaa tacttcagca gttcaggtct
3481 taattgagca tattggaaac ttggatcggg catatgagtt tgctgaacgt tgcaatgaac
3541 ctgcggtctg gagtcaactt gcaaaagccc agttgcagaa aggaatggtg aaagaagcca
3601 ttgattctta tatcaaagca gatgatcctt cctcctacat ggaagttgtt caggctgcca
3661 atactagtgg aaactgggaa gaactggtga agtacttgca gatggcccgt aagaaggctc
3721 gagagtccta tgtggagaca gaactgatat tcgcactggc taaaacaaac cgccttgcag
3781 agttagaaga atttatcaat ggaccaaata atgctcatat ccaacaagtt ggtgaccgtt
3841 gttatgatga aaaaatgtat gatgctgcta agttgttgta caataatgtt tccaattttg
3901 gacgtttggc atctaccctg gttcacctgg gtgaatatca ggcagctgtt gatggggcta
3961 ggaaagctaa cagtactcga acatggaaag aggtctgctt cgcctgtgta gatgggaaag
4021 aattccgtct tgctcagatg tgtggacttc atattgttgt acatgcagat gaattagaag
4081 aacttatcaa ctactatcag gatcgtggct attttgaaga gctgatcacc atgttggaag
4141 cagcactggg acttgagcga gctcacatgg gaatgtttac tgaattagct attctatact
4201 ctaaatttaa gcctcagaaa atgagggagc acctggagct gttctggtct agagtgaata
4261 ttcccaaggt gctaagagct gcagaacaag ctcatctttg ggcagaactg gtgtttttgt
4321 atgacaagta tgaagaatat gataatgcca taattaccat gatgaatcat ccaactgatg
4381 cctggaaaga agggcaattc aaagatatca ttaccaaggt tgccaatgtg gaactatact
4441 acagagcaat acagttctac ttagaattca agcctctgtt gttaaatgat ttgctgatgg
4501 tgctgtctcc acggttggat cacactcgtg cagtcaatta tttcagcaag gttaaacagc
4561 taccactggt gaaaccgtat ttgcgttcag ttcagaacca taacaacaaa tctgtgaatg
4621 aatcattgaa caatcttttt attacagaag aagattatca ggctctgcga acatcaatag
4681 atgcttatga caactttgac aatatctcgc ttgctcagcg tttggaaaaa catgaactca
4741 ttgagttcag gagaattgct gcttatctct tcaaaggcaa caatcgctgg aaacagagtg
4801 tagagctgtg caagaaagac agcctttaca aggatgcaat gcagtatgct tctgaatcta
4861 aagatactga attggctgaa gaactcctgc agtggttttt gcaggaagaa aaaagagagt
4921 gctttggagc ttgtctgttt acctgttacg atcttttaag gccagatgtc gtcctagaaa
4981 ctgcatggag gcacaatatc atggattttg ccatgcccta tttcatccag gtcatgaagg
5041 agtacttgac aaaggtggat aaattagatg cttcagaatc actgagaaaa gaagaagaac
5101 aagctacaga gacacaaccc attgtttatg gtcagcccca gttgatgctg acagcaggac
5161 ccagtgttgc cgtccctccc caggcacctt ttggttatgg ttataccgca ccaccgtatg
5221 gacagccaca gcctggcttt gggtacagca tgtgagatga agcgctgatc ctgtagtcac
5281 ctattttcgt actgaaacat cgtctttacc cacttctcag tttataatgg gggaaaacag
5341 gcaacgtgtt cttgtaacct ttatttcatg aaggacttct ttttgtttct aactataaac
5401 ttggatcacc tatgttaaaa ccttatttca cattccacat cattttagaa tttattttcg
5461 aaggggaata gtttcaatgt tttattcact tgggcttttt ttcttccccc tctttcttta
5521 aagaactgct caatattcaa tctgttgtga agaacctgat ttgcactctg tagtgtttaa
5581 agaaacaaag aaactctaat attgaatctc ttaaatttag tgtatgtaaa cagcttacaa
5641 atacgtattg tctaaatgca tttaaatctg ttttattcaa agaaaagcta aagcaaaaac
5701 actggcatat gaccatgcaa gactgtcagt gccaacaaag acaacactaa tcagcacatc
5761 gtacactgga ttgcagtgct tcccagatta ttgaaaaatg ttacagacaa cttgcctgat
5821 ttttaaatga gcgtaaaagg ccctctaacc tatgcaggtt tccccattat gcatatagaa
5881 aatgctagta tgttttgctc acttcatatg taacaggtgc ccttatgttg tgctgtatcc
5941 tgtgcttttt ctgtgggacc attccattca ggagcaaaga gcaccatgat tccaatcttg
6001 tgtgtgttta ctaacccttc cctgaggttt gtgtatgttg gatattgtgg tgttttagat
6061 cactgagtgt acagaagaga gaaattcaaa caaaatattg ctgttcttca gttttgtttg
6121 tggaatttga aattactcaa atttaaaata aattactgga ctgtggaaat aacatagaat
6181 tgaagtttta attaaatacc actcaaacga aaagaacagt agtttttgta gttttatatt
6241 ggatactgag gcattaggga ggcatgaaag gaagaggaat gaggattgag acatgtgaag
6301 acattgtgca ttatatcaat gtgcattcct gtagttcatt aacaaggtac atgcaatagt
6361 ctaaagaacc agagtcacta ctatagtggc ttaacattta atctgtctcc aatattttaa
6421 ccaagtgaca ccgaggtttt tatcgaagca tttcacttaa atgaacaaat catggctgtt
6481 atattaactt gaaataaaat atatttaaac atgtaaaaaa aaaaaaaaa
//