LOCUS BC053903 4426 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens SLIT-ROBO Rho GTPase activating protein 1, mRNA (cDNA
clone MGC:61613 IMAGE:6526787), complete cds.
ACCESSION BC053903
VERSION BC053903.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4426)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4426)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (13-JUN-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 115 Row: p Column: 4
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 44917603.
FEATURES Location/Qualifiers
source 1..4426
/db_xref="H-InvDB:HIT000054023"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:61613 IMAGE:6526787"
/tissue_type="Uterus, leiomyosarcoma"
/clone_lib="NIH_MGC_71"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..4426
/gene="SRGAP1"
/gene_synonym="ARHGAP13"
/gene_synonym="KIAA1304"
/db_xref="GeneID:57522"
/db_xref="HGNC:HGNC:17382"
/db_xref="MIM:606523"
CDS 57..3314
/gene="SRGAP1"
/gene_synonym="ARHGAP13"
/gene_synonym="KIAA1304"
/codon_start=1
/product="SLIT-ROBO Rho GTPase activating protein 1"
/protein_id="AAH53903.1"
/db_xref="GeneID:57522"
/db_xref="HGNC:HGNC:17382"
/db_xref="MIM:606523"
/translation="MSTPSRFKKDKEIIAEYESQVKEIRAQLVEQQKCLEQQTEMRVQ
LLQDLQDFFRKKAEIETEYSRNLEKLAERFMAKTRSTKDHQQYKKDQNLLSPVNCWYL
LLNQVRRESKDHATLSDIYLNNVIMRFMQISEDSTRMFKKSKEIAFQLHEDLMKVLNE
LYTVMKTYHMYHAESISAESKLKEAEKQEEKQIGRSGDPVFHIRLEERHQRRSSVKKI
EKMKEKRQAKYSENKLKSIKARNEYLLTLEATNASVFKYYIHDLSDLIDCCDLGYHAS
LNRALRTYLSAEYNLETSRHEGLDIIENAVDNLEPRSDKQRFMEMYPAAFCPPMKFEF
QSHMGDEVCQVSAQQPVQAELMLRYQQLQSRLATLKIENEEVKKTTEATLQTIQDMVT
IEDYDVSECFQHSRSTESVKSTVSETYLSKPSIAKRRANQQETEQFYFMKLREYLEGS
NLITKLQAKHDLLQRTLGEGHRAEYMTTRPPNVPPKPQKHRKSRPRSQYNTKLFNGDL
ETFVKDSGQVIPLIVESCIRFINLYGLQHQGIFRVSGSQVEVNDIKNSFERGENPLAD
DQSNHDINSVAGVLKLYFRGLENPLFPKERFNDLISCIRIDNLYERALHIRKLLLTLP
RSVLIVMRYLFAFLNHLSQYSDENMMDPYNLAICFGPTLMPVPEIQDQVSCQAHVNEI
IKTIIIHHETIFPDAKELDGPVYEKCMAGDDYCDSPYSEHGTLEEVDQDAGTEPHTSE
DECEPIEAIAKFDYVGRSARELSFKKGASLLLYHRASEDWWEGRHNGIDGLVPHQYIV
VQDMDDTFSDTLSQKADSEASSGPVTEDKSSSKDMNSPTDRHPDGYLARQRKRGEPPP
PVRRPGRTSDGHCPLHPPHALSNSSVDLGSPSLASHPRGLLQNRGLNNDSPERRRRPG
HGSLTNISRHDSLKKIDSPPIRRSTSSGQYTGFNDHKPLDPETIAQDIEETMNTALNE
LRELERQSTAKHAPDVVLDTLEQVKNSPTPATSTESLSPLHNVALRSSEPQIRRSTSS
SSDTMSTFKPMVAPRMGVQLKPPALRPKPAVLPKTNPTIGPAPPPQGPTDKSCTM"
BASE COUNT 1329 a 1053 c 1014 g 1030 t
ORIGIN
1 gttgtgacca ctgaacaaaa cttgcccatt gaaagcaaac ccggaacagc tggataatgt
61 ccaccccgag ccgattcaag aaggacaaag agatcatagc cgagtatgaa agtcaagtca
121 aagaaattcg agctcaactg gtagaacaac aaaaatgcct ggagcagcaa acggagatgc
181 gagttcagct tctccaggat ctgcaagatt tcttccgaaa aaaagctgaa attgagacgg
241 aatattcccg gaatctagag aagttagcag aaaggttcat ggcaaaaaca agaagcacta
301 aggatcatca acaatacaag aaagaccaga acctgttgtc tccagtgaac tgctggtatt
361 tgctcctgaa ccaagtaagg agagaaagca aagaccatgc aaccttgagt gacatctatc
421 tgaacaatgt gattatgcgg ttcatgcaga taagtgagga ttctaccagg atgtttaaaa
481 agagcaaaga gattgcattc caacttcatg aggatttaat gaaggttctt aatgagcttt
541 atacggtgat gaaaacatac catatgtatc atgcagagag catcagtgca gagagcaagc
601 tgaaagaggc cgaaaaacaa gaggaaaagc aaattgggag atctggtgat ccagtcttcc
661 atattcgact agaggagaga catcaacggc gaagctctgt aaagaaaatt gaaaaaatga
721 aagaaaaaag acaagcaaaa tattcagaaa ataagctaaa atcaattaag gcacggaacg
781 aatatctcct aacacttgaa gccaccaatg cctcagtttt caagtactat attcatgatc
841 tttctgattt aattgattgc tgtgatcttg gctaccatgc aagtctgaac agagccctaa
901 gaacatatct gtctgcggag tacaaccttg aaacctccag acatgagggc ttagacatta
961 ttgagaatgc agttgataat ttagagccca ggagcgataa gcagagattc atggagatgt
1021 accctgctgc gttctgtcca ccaatgaagt ttgagtttca gtctcacatg ggtgatgagg
1081 tgtgccaggt cagtgcccag cagccagtcc aggcagagct catgctcagg taccaacagt
1141 tgcagtcccg ccttgccacg ctcaaaatcg agaatgaaga ggttaagaaa acgactgaag
1201 ccaccttgca gacgatacaa gatatggtca ccatcgagga ctatgatgtt tctgaatgct
1261 tccagcacag tcgttccaca gaatctgtga agtccactgt ctctgaaacc tacctgagta
1321 aacccagcat cgccaagaga agagccaacc agcaggaaac tgaacagttc tacttcatga
1381 aactcagaga atatttggaa ggcagtaatc tcatcacaaa acttcaagcc aaacatgact
1441 tgctgcagag gaccctggga gaaggtcata gagctgaata tatgactaca aggcctccaa
1501 atgttccccc taagccccag aaacacagga agtccaggcc ccgctcacag tataatacta
1561 agttgtttaa tggggatttg gaaacattcg tcaaggactc aggacaggtt attcccctca
1621 ttgtggaaag ctgtattcgg ttcatcaatc tctatggtct tcagcatcag gggattttca
1681 gagtgtctgg ttcccaggtg gaagtcaatg atattaaaaa ttcatttgag agaggtgaaa
1741 atcctttggc tgatgaccag agtaaccatg atattaactc agttgctggc gttctgaagc
1801 tctatttccg tgggctggaa aaccccctct ttcctaagga aagatttaac gatctgattt
1861 cttgtatcag aatagataat ctctatgaga gggcgcttca catccgcaaa ctcctcctga
1921 ctttgcccag gtcggtcctt atagtgatga ggtacctctt tgccttcctc aatcatctat
1981 cacagtacag cgatgagaat atgatggacc cttataacct ggccatttgc tttggcccaa
2041 cattgatgcc tgtcccagaa atacaggatc aagtgtcttg ccaggcacat gtgaatgaaa
2101 ttatcaaaac catcatcatc caccatgaga ctattttccc agatgctaaa gagctggatg
2161 gccctgttta tgagaaatgt atggctggag atgactattg cgacagccca tacagtgagc
2221 acggtacatt ggaggaagtg gaccaagatg ctggtacaga gccccacaca agtgaagatg
2281 aatgtgagcc aatagaagca atagccaagt ttgactatgt tgggcggtcc gccagagaac
2341 tatccttcaa gaagggtgcc tccctgctgc tgtatcaccg tgcatctgag gactggtggg
2401 aaggcaggca caacgggatt gacgggctgg tgcctcacca gtatatagtg gtgcaggata
2461 tggatgatac gttttcagac actctgagcc aaaaagccga cagtgaggcc agcagtgggc
2521 cagtcacgga agacaagtcc tcatccaagg acatgaactc cccgacagac cgtcatcctg
2581 acggctattt agccaggcaa cgaaaaagag gagagccacc ccctccagta aggcgtcctg
2641 gcaggaccag tgatggccat tgcccgctcc accctccaca tgccctttct aactcctcag
2701 ttgacctagg gtccccaagc cttgccagtc acccccgggg cctgctgcag aaccgtggcc
2761 tcaacaatga cagtcctgag cggaggcgca ggcctggcca tggcagcctg accaacatca
2821 gccggcacga ctccctcaag aagatcgaca gccctcccat tagaaggtcc acgtcatcag
2881 ggcaatacac gggcttcaat gaccacaagc cactggaccc agagacaatt gctcaggata
2941 ttgaagaaac gatgaacaca gctttgaatg aactccgaga actggagaga cagagcacag
3001 caaagcatgc ccctgatgtg gtgctggata ccctggagca agtgaaaaac tctcccaccc
3061 ctgccacttc cacggaatct ctcagccctt tgcacaacgt tgccctcagg agctccgagc
3121 ctcagattcg acgtagcacg agctcctcca gtgacacaat gagtactttc aagcctatgg
3181 tggcacccag aatgggcgtg cagctgaagc ctccagccct taggccaaaa cctgctgttc
3241 ttccaaaaac aaatcctacc ataggacctg ccccacctcc ccagggtcca acagacaagt
3301 catgcacaat gtaaaaacca gccaagcaag gccataaagg gaggtgactt aaaaaagaaa
3361 atggattagt gacaaaagtc actgatccat aactttcctt agttttgtgc ttataactgg
3421 agatcttttg gcttttctat gttgtcgaat gtaatgtctg agactagcta aattaacacg
3481 ggcatttgta ttttgtaatt tttttaaata actggacata tgtcatttta aggacaatag
3541 aaacacttag acttacttga aaatccaatg ctgcaccact tgtaatgaag gcaacaccgc
3601 tctccacatt gtacagagct tcaggtttaa tgtagcccag ctgagtcaga aaggttgtga
3661 cctgaaggca gaagaacccg aatgccacac ctcattggag tatagccagt gttggtctgt
3721 ggcacttggg ctgaaaggtg ataatggcat tgcgtggtag ctgacaatga gcaccttcgg
3781 ttccatgtgg agcggggttt agctcatgca aaagacttgc aattgtctcc atgggacgat
3841 cccagtggga ctgtcagccc acagctcgag tgggttggat gcttgcctct ttcctaacag
3901 ttatttcccc gggtccagct taaagactcg atggaaggag gtagaacctc tgctgttact
3961 gcttgaactt aacctgggaa aggagaggaa gacaccatct ccaaagctat taatgtcact
4021 ccttttgcga gcatgattag gccccggaga tttccaagtc cccccatcta cacttacaaa
4081 cgattagaag ggtttaattt taaagacttt ctggttacac tactccacga actcctccaa
4141 agatccgtta ttcaataact gcctagaaaa tgtttccatc tcctctaaat ccctgtgttc
4201 tcctctgtgg aaatgaaggc agcaagaagc acctgaggcc ttggttcatg cagtgttctc
4261 ttttgactaa atcacctagg ttcctttaaa catgctacaa agcccaggca tggtggtgca
4321 cacctgtact cccagctact cgggtgtact aggctttggg cctagtagtt cgagtccagc
4381 ctgggcagca tagtgtgaga ccctgtctct taaaaaaaaa aaaaaa
//