LOCUS BC053866 2698 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens endothelin 3, mRNA (cDNA clone MGC:61498
IMAGE:5202210), complete cds.
ACCESSION BC053866
VERSION BC053866.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2698)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2698)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (13-JUN-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 115 Row: d Column: 14
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 46370058.
FEATURES Location/Qualifiers
source 1..2698
/db_xref="H-InvDB:HIT000054000"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:61498 IMAGE:5202210"
/tissue_type="Lung, Spleen, fetal, pooled"
/clone_lib="NIH_MGC_122"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2698
/gene="EDN3"
/gene_synonym="ET3"
/gene_synonym="MGC15067"
/gene_synonym="MGC61498"
/db_xref="GeneID:1908"
/db_xref="HGNC:HGNC:3178"
/db_xref="MIM:131242"
CDS 371..1030
/gene="EDN3"
/gene_synonym="ET3"
/gene_synonym="MGC15067"
/gene_synonym="MGC61498"
/codon_start=1
/product="endothelin 3"
/protein_id="AAH53866.1"
/db_xref="GeneID:1908"
/db_xref="HGNC:HGNC:3178"
/db_xref="MIM:131242"
/translation="MEPGLWLLFGLTVTSAAGFVPCSQSGDAGRRGVSQAPTAARSEG
DCEETVAGPGEETVAGPGEGTVAPTALQGPSPGSPGQEQAAEGAPEHHRSRRCTCFTY
KDKECVYYCHLDIIWINTPEQTVPYGLSNYRGSFRGKRSAGPLPGNLQLSHRPHLRCA
CVGRYDKACLHFCTQTLDVSSNSRTAEKTDKEEEGKVRGANRGLCQRRLKSRTNKASR
L"
BASE COUNT 722 a 675 c 706 g 595 t
ORIGIN
1 cctcgggccg ctgcgctcct ggccagctcc ccccagcgcc tgggaggcga cccccagtgc
61 gcccgggttc aaaggcccgg cgaggcagtt ccagcccctc tggggggcgg ggaggcgacg
121 ggggtggtgc agaagccaga aaagcccgag ccacagccgg ccagctccgc gcagggatgg
181 gcagcgcgct ctgaaagttt atgaccgccg cagccaactc ctggccggag ctggagacgc
241 agcgagcgat cggccggcct cgaaccccca cagctggagg gcgaggccag ctgtacccgg
301 ccccagtgcc ctttcgcggc cacaagcggc cgtcctcctg gtccggtgct ccggcgcctg
361 atctaggttc atggagccgg ggctgtggct ccttttcggg ctcacagtga cctccgccgc
421 aggattcgtg ccttgctccc agtctgggga tgctggcagg cgcggcgtgt cccaggcccc
481 cactgcagcc agatctgagg gggactgtga agagactgtg gctggccctg gcgaggagac
541 tgtggctggc cctggcgagg ggactgtggc cccgacagca ctgcagggtc caagccctgg
601 aagccctggg caggagcagg cggccgaggg ggcccctgag caccaccgat ccaggcgctg
661 cacgtgcttc acctacaagg acaaggagtg tgtctactat tgccacctgg acatcatttg
721 gatcaacact cccgaacaga cggtgcccta tggactgtcc aactacagag gaagcttccg
781 gggcaagagg tctgcggggc cacttccagg gaatctgcag ctctcacatc ggccacactt
841 gcgctgcgct tgtgtgggga gatatgacaa ggcctgcctg cacttttgca cccaaactct
901 ggacgtcagc agtaattcaa ggacggcaga aaaaacagac aaagaagagg aagggaaggt
961 gagaggtgcc aacagaggcc tgtgtcaaag gaggttgaag tcaaggacca acaaagcaag
1021 caggctttag acctccacca tccaaagctc atgcccggca gtggactcgc cctcgctcca
1081 tctacctgcc cccgctgcct ctttcaggaa ggagcccctt aggaggacag gcctgcagca
1141 tcctggtctc gggaggcttc tgtcattgct cacacacagt tcagatttcc acctctttat
1201 agacaagaag tgaatttgcc tggggcagaa cacccaccca aagagtcccc acttaacaat
1261 acccccctcc cacggcaaga atgcccaaat ccaaatgacc ccagttttcc taatgagtaa
1321 aatgatccca gatgtgcccc agagcatgac gcctgcagct ccggtttcat gcaggaaatt
1381 ggttttggag agttttggca agttggaaag ccacttactg gcttttgaca tgacttctct
1441 tggagaataa gtggactcca agctaactct ttgcaaatgt aaacacatgt ccatcttgta
1501 ataaatgcaa aatgcccgtg cagcagaagc atgcgacttt catatccttg cctagaatag
1561 gctgcatggt gtatgtcagt gagggccacg aggcgtcggc tttagacaca gatcatagct
1621 ctacaggagt ttatgaattt gaagcttatg ggattttggc agagaaattt tcagctgtgc
1681 ttgataccca ccaaaagaat gtatctcgaa agaatgaagg aagaagaaaa aaggatcctt
1741 gatgtttgtg acaagaaaat gagaaagtta gtatctgcaa tacagagctt gttcctgttc
1801 agtgactgac cctctgtatt ctgtatagac accaggccga tacacagtgg agttcccagg
1861 ccttgtttgc aggaagccga ctgtaaagac agccccagct caaggctatt aggttgaata
1921 tttgctttca tgagtaaatg tggatctttg gggaatggct tcaaaataag tcacgaacac
1981 aaattctttg taaattatgt aaattcctgt ttatataaat tggcaacaac ttataccgtc
2041 tgacagttca aaatctcttt cagctgcgct cttcccaccg agccgagctt actgtgagtg
2101 tggagatgtt atcccaccat gtaaagtcgc ctgcgcaggg gagggctgcc catctcccca
2161 acccagtcac agagagatag gaaacggcat ttgagtgggt gtccagggcc ccgtagagag
2221 acatttaaga tggtgtatga cagagcattg gccttgacca aatgttaaat cctctgtgtg
2281 tatttcataa gttattacag gtataaaagt gatgacctat catgaggaaa tgaaagtggc
2341 tgatttgctg gtaggatttt gtacagttta gagaagcgat tatttattgt gaaactgttc
2401 tccactccaa ctcctttatg tggatctgtt caaagtagtc actgtatata cgtatagaga
2461 ggtagatagg taggtagatt ttaaattgca ttctgaatac aaactcatac tccttagagc
2521 ttgaattaca tttttaaaat gcatatgtgc tgtttggcac cgtggcaaga tggtatcaga
2581 gagaaaccca tcaattgctc aaatactcag aaagtactgt caaaagccta ataaaaaacc
2641 taaagtttaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaa
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