LOCUS BC053860 3460 bp mRNA linear HUM 24-JUN-2003
DEFINITION Homo sapiens kelch-like 5 (Drosophila), mRNA (cDNA clone
IMAGE:6167982), partial cds.
ACCESSION BC053860
VERSION BC053860.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3460)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3460)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (13-JUN-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC/DCTD/DTP
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 115 Row: n Column: 15
This clone was selected for full length sequencing because it
passed the following selection criteria: GenomeScan gene
prediction.
FEATURES Location/Qualifiers
source 1..3460
/db_xref="H-InvDB:HIT000259352"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:6167982"
/tissue_type="Skin, melanotic melanoma."
/clone_lib="NIH_MGC_72"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene <1..3460
/gene="KLHL5"
/db_xref="GeneID:51088"
CDS <1..2291
/gene="KLHL5"
/codon_start=3
/product="KLHL5 protein"
/protein_id="AAH53860.1"
/db_xref="GeneID:51088"
/translation="CGTPAWPPRPAVTHGRLRSPTRRAYTSLVLVGCTNLCAVLFARC
LDDHLVSLRMSGSRKEFDVKQILKIRWRWFGHQASSPNSTVDSQQGEFWNRGQTGANG
GRKFLDPCSLQLPLASIGYRRSSQLDFQNSPSWPMASTSEVPAFEFTAEDCGGAHWLD
RPEVDDGTSEEENESDSSSCRTSNSSQTLSSCHTMEPCTSDEFFQALNHAEQTFKKME
NYLRHKQLCDVILVAGDRRIPAHRLVLSSVSDYFAAMFTNDVREARQEEIKMEGVEPN
SLWSLIQYAYTGRLELKEDNIECLLSTACLLQLSQVVEACCKFLMKQLHPSNCLGIRS
FADAQGCTDLHKVAHNYTMEHFMEVIRNQEFVLLPASEIAKLLASDDMNIPNEETILN
ALLTWVRHDLEQRRKDLSKLLAYIRLPLLAPQFLADMENNVLFRDDIECQKLIMEAMK
YHLLPERRPMLQSPRTKPRKSTVGTLFAVGGMDSTKGATSIEKYDLRTNMWTPVANMN
GRRLQFGVAVLDDKLYVVGGRDGLKTLNTVECYNPKTKTWSVMPPMSTHRHGLGVAVL
EGPMYAVGGHDGWSYLNTVERWDPQARQWNFVATMSTPRSTVGVAVLSGKLYAVGGRD
GSSCLKSVECFDPHTNKWTLCAQMSKRRGGVGVTTWNGLLYAIGGHDAPASNLTSRLS
DCVERYDPKTDMWTAVASMSISRDAVGVCLLGDKLYAVGGYDGQAYLNTVEAYDPQTN
EWTQVAPLCLGRAGACVVTVKL"
BASE COUNT 1039 a 621 c 756 g 1044 t
ORIGIN
1 gctgtgggac tcccgcctgg ccgccccggc ccgccgtgac ccacggccgc ctccggagcc
61 cgacgcgcag ggcatatact tctcttgtct tggttggatg cacaaatctg tgtgcagtgc
121 tttttgcccg ttgcctagac gatcacttgg tttctctgag gatgtctggt tctcgtaaag
181 agtttgatgt gaaacagatt ttgaaaatca gatggaggtg gtttggtcat caagcatcat
241 ctcctaattc tacagttgac agccagcagg gagaattttg gaaccgagga cagactggag
301 caaacggtgg gagaaagttt ttagatccat gtagcctaca attgcctttg gcttcaattg
361 gttaccgaag gtccagccaa ctggattttc agaattcacc ttcttggcca atggcatcca
421 cctctgaagt ccctgcattt gagtttacag cagaagattg tggcggtgca cattggctgg
481 atagaccaga agtggatgat ggcactagtg aagaagaaaa tgaatctgat tccagttcat
541 gcaggacttc caatagtagt cagacattat catcctgtca tactatggag ccatgtacat
601 cagatgaatt tttccaagcc cttaatcatg ccgagcaaac atttaaaaaa atggaaaact
661 atttgagaca taaacagttg tgtgatgtaa ttttagtcgc tggtgatcgc agaattccag
721 ctcacagatt ggtgctctcc tctgtctcag actattttgc tgccatgttt actaatgatg
781 tcagagaggc aagacaagaa gaaataaaaa tggaaggtgt agaaccaaat tcgttgtggt
841 ccttgatcca gtatgcttat acaggccgcc ttgaattaaa agaagataat attgagtgcc
901 tgttatctac agcttgcctt cttcagcttt cacaggttgt agaagcatgc tgtaagtttt
961 taatgaaaca gcttcatcca tccaactgtc ttggaattcg ttcttttgct gatgcccaag
1021 gttgtacaga tttgcataaa gtggctcaca attatactat ggagcatttc atggaagtaa
1081 tcagaaacca ggaatttgta ttattaccag ccagcgaaat tgcaaagctc ttggctagtg
1141 atgacatgaa cattcctaat gaggagacaa tattgaatgc acttcttact tgggtccgtc
1201 atgatttgga acagagacgg aaagatctaa gtaaactttt ggcttatatt aggctacctc
1261 ttcttgcacc acagttcctg gcagacatgg aaaataatgt actttttcgg gatgatatag
1321 aatgtcagaa actcattatg gaagcaatga agtaccattt attaccagag agacgaccca
1381 tgttacaaag tcctcggaca aaacctagga agtcaactgt tggtacatta tttgcagttg
1441 ggggaatgga ttcaacaaaa ggagcaacaa gcattgaaaa gtatgatctc cgtacaaata
1501 tgtggactcc agtagcaaat atgaatggga ggaggctaca gttcggtgtt gcagtgctag
1561 atgacaaact gtatgtggtt ggaggaagag atggactgaa gactttgaat actgtagagt
1621 gctacaaccc caaaacaaaa acttggagtg tgatgccacc tatgtccaca catagacatg
1681 gccttggtgt ggctgtactg gaaggtccca tgtatgccgt aggaggacat gatggctgga
1741 gctatctgaa cacagtggaa agatgggacc ctcaggctcg ccagtggaat tttgttgcca
1801 ctatgtctac ccctaggagt acagtaggtg tggcagtact aagtggaaaa ctttatgcag
1861 ttggtggtcg tgatggaagt tcttgtctca aatcagtaga atgttttgat cctcatacta
1921 ataagtggac actgtgtgca cagatgtcaa aaaggagagg tggcgtagga gtgacgacct
1981 ggaatggact gctgtatgct ataggggggc acgatgctcc cgcatccaac ttgacttcca
2041 gactctcaga ctgtgtggaa agatatgatc ccaaaacaga catgtggact gcagtagcat
2101 ccatgagcat cagcagagat gcagtggggg tctgtttact tggtgataag ttatatgctg
2161 ttggggggta tgatggacag gcatacctta atactgtgga ggcttatgat ccccagacaa
2221 atgagtggac ccaggttgct ccactgtgcc taggaagagc tggagcttgt gttgtgactg
2281 taaaattata atttagtgcc ccgttttcta catgaagaca ccgtcttcct ttattaattt
2341 agtataatta ttctatcaat ggatacattt ttagtaaatg tgcattgtca caatcctggg
2401 cacaaagtgc ctgatgtcaa aatgaagata gtaaaacaag ggaggaagca gtggatggac
2461 caggattaat tcctttcatt tcttagtaaa ttaaaacctg cagctggtgg attgtgatca
2521 cacattcccg aagtaataag tgaggacgaa tgcactgctc tggaacataa cccagtgcta
2581 actgggggtt tcatttattc agtcaagcac atcttactca catccagatt tattttccta
2641 cagtgcaaac acaccagatg aaactttaaa atgttacttt ttgtaagctt atcataaatg
2701 agttgcagta atttgtttgc ttgtttgttt aaccacaacc actattttaa tgatatacta
2761 aagataacac tatttagttt tttcagaaac atctgcatta tatgtgtgtt ggttgtggat
2821 tttgtttcta aaattggctt agtccaataa ataaagaaaa gcattaagga cttaaagcaa
2881 caataaccaa ataaaaactt gataggatct ttgaagtcta tttaaatatt cattccatta
2941 catctagact caccaagaac tacatgttat gatgttaagt tgaagttgaa acatgatgtt
3001 ttgcattaaa tttaagatat gcaaatttat gtagagaaaa taaatgttat ataccctata
3061 atctttcacc taattagtat ttaattatat ggatttgttt tatattataa aagatgtttt
3121 gattttgtct tttgatattg acaaaattgt ttggatatcc ttatgttctc aagtctgtat
3181 ctgcctcccc tgccttattt cttatgtttt gccacagtta acccattgtg cttctttgta
3241 atcaaacagt ttgtgggaga atgggcttat tgaatgtcta aaaaataagt ttaaagtgtt
3301 tgttacccta agttttttac atttttaaac tctaattaca tatgtgaatg ttattactct
3361 cagtgaattg ttattgtttg caaaaatgca ctgggcagta acattttgtg ataaatccta
3421 taagatataa gtcaaaaaaa aaaaaaaaaa aaaaaaaaaa
//