LOCUS BC053845 2794 bp mRNA linear HUM 08-OCT-2003
DEFINITION Homo sapiens GLI-Kruppel family member HKR1, mRNA (cDNA clone
MGC:61630 IMAGE:5493685), complete cds.
ACCESSION BC053845
VERSION BC053845.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2794)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2794)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (13-JUN-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 115 Row: e Column: 23
This clone was selected for full length sequencing because it
passed the following selection criteria: Similarity but not
identity to protein.
FEATURES Location/Qualifiers
source 1..2794
/db_xref="H-InvDB:HIT000053987"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:61630 IMAGE:5493685"
/tissue_type="Eye, retinoblastoma"
/clone_lib="NIH_MGC_67"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2794
/gene="HKR1"
/db_xref="GeneID:284459"
/db_xref="MIM:165250"
CDS 290..2086
/gene="HKR1"
/codon_start=1
/product="HKR1 protein"
/protein_id="AAH53845.1"
/db_xref="GeneID:284459"
/db_xref="MIM:165250"
/translation="MLETYNHLVSLEIPSSKPKLIAQLERGEAPWREERKCPLDLCPE
SKPEIQLSPSCPLIFSSQQALSQHVWLSHLSQLFSSLWAGNPLHLGKHYPEDQKQQQD
PFCFSGKAEWIQEGEDSRLLFGRVSKNGTSKALSSPPEEQQPAQSKEDNTVVDIGSSP
ERRADLEETDKVLHGLEVSGFGEIKYEEFGPGFIKESNLLSLQKTQTGETPYMYTEWG
DSFGSMSVLIKNPRTHSGGKPYVCRECGRGFTWKSNLITHQRTHSGEKPYVCKDCGRG
FTWKSNLFTHQRTHSGLKPYVCKECGQSFSLKSNLITHQRAHTGEKPYVCRECGRGFR
QHSHLVRHKRTHSGEKPYICRECEQGFSQKSHLIRHLRTHTGEKPYVCTECGRHFSWK
SNLKTHQRTHSGVKPYVCLECGQCFSLKSNLNKHQRSHTGEKPFVCTECGRGFTRKST
LSTHQRTHSGEKPFVCAECGRGFNDKSTLISHQRTHSGEKPFMCRECGRRFRQKPNLF
RHKRAHSGAFVCRECGQGFCAKLTLIKHQRAHAGGKPHVCRECGQGFSRQSHLIRHQR
THSGEKPYICRKCGRGFSRKSNLIRHQRTHSG"
misc_feature 290..382
/gene="HKR1"
/note="KRAB; Region: krueppel associated box"
/db_xref="CDD:smart00349"
misc_feature 1253..2083
/gene="HKR1"
/note="COG5048; Region: COG5048, FOG: Zn-finger [General
function prediction only]"
/db_xref="CDD:COG5048"
BASE COUNT 789 a 650 c 719 g 636 t
ORIGIN
1 aactgacgtg ctgagcagct aattcagtgc ctgaggttac actagttgtg gacagagatg
61 ggttccaaat ccagatagta tgggttgaat ccacgctctt catcaccacc cactttccct
121 ccttaggcct gagcaggcac atggcagcat ttggtagagg aaggagtgag ccctgctgta
181 ggaactatat atattggcgt tcgtggcatt cagggatgtg gctgtgtact tcacccagga
241 ggagtggagg ttgttgagcc ctgctcagag gaccctgcac agggaggtga tgctggagac
301 ttataaccat ctggtctcac tggaaattcc atcttctaaa ccaaaactca ttgctcagct
361 ggagcgaggg gaagcgccct ggagagagga gagaaaatgt ccactggacc tctgtccaga
421 atcgaagcca gaaattcaac ttagtccctc ctgccctctg attttctcca gtcagcaagc
481 tctcagccaa catgtgtggc tgagtcatct ctctcagctg ttttcaagtt tatgggcagg
541 aaatcctctc cacctgggaa aacactatcc agaagatcag aaacaacagc aggatccatt
601 ctgctttagt ggcaaagcag aatggattca agagggagaa gactccagac tcctgtttgg
661 gagagtaagc aaaaatggca cttcaaaggc actttccagc ccacctgaag aacaacagcc
721 agcacagtcc aaggaagaca acacagtggt ggatataggg tccagccctg aacggagggc
781 agatctagag gaaacagaca aagtattgca tggtttagaa gtctcaggat ttggagaaat
841 caaatatgaa gagtttgggc caggctttat caaggagtca aacctcctta gcctccagaa
901 gacacaaact ggggagacac cttacatgta cactgagtgg ggagacagct ttggcagtat
961 gtcagtcctc atcaaaaacc caaggacaca ctctggggga aagccttatg tgtgcaggga
1021 atgtgggcga ggctttacgt ggaagtcaaa cctgatcaca catcagagga cacactcagg
1081 ggagaaacct tatgtgtgca aggattgtgg acgaggcttt acttggaagt cgaacctctt
1141 tacacatcag cggacacact cagggctcaa gccttatgtg tgcaaggaat gtgggcagag
1201 ctttagcctg aagtcaaacc tcattaccca ccagagggcg cacactgggg agaagcctta
1261 tgtttgcagg gaatgtgggc gtggctttcg ccagcattca cacctggtca gacacaagag
1321 gacacattca ggagagaagc cttacatttg cagggagtgt gagcaaggct ttagccagaa
1381 gtcacacctc atcagacact taaggacaca cacaggagag aagccttatg tatgcacaga
1441 atgtgggcgt cactttagct ggaaatcaaa cctcaaaaca caccagagga cacactcagg
1501 ggttaaacct tatgtctgcc tggagtgcgg gcagtgcttt agcctgaagt caaaccttaa
1561 caaacaccag aggtcacaca cgggggagaa gccatttgta tgtacggagt gtgggcgagg
1621 ctttacccgg aaatcaaccc tgagcacgca ccagaggaca cactcagggg agaagccatt
1681 tgtatgtgct gagtgtggac gaggctttaa tgataagtcc accctcattt cacaccagag
1741 gacacattca ggggaaaagc cttttatgtg cagggagtgt ggcagaaggt ttcggcagaa
1801 gcctaacctg tttaggcaca agagggcaca ctcaggtgcc tttgtgtgca gggagtgtgg
1861 gcaaggcttt tgtgctaagt taactctcat taaacaccag agagcacacg caggggggaa
1921 gcctcatgtg tgcagggagt gtgggcaagg ctttagccgg cagtcacacc tcattagaca
1981 ccagaggaca cattcaggag agaagcctta tatttgcaga aagtgtggac ggggctttag
2041 tcggaagtcc aaccttatca gacatcagag gacacactca ggatagaaac tttatgtgta
2101 tagggaatgt ggtacagcct ttagccagga gtcatacttc atcagacacc agaggacaca
2161 cacagtgctg tggctttttc agccattgct agataccaaa gtggagacat tctgtgtgtg
2221 attatgcatg agactgtact ggtaagactt gtatctccat ccacctgaag gagaattgct
2281 ggctcatttt caggagccct gcccttcctc actgtggatg gtgggttgtg gaaacccggt
2341 caggtaatga tagtggcagg aggcagtcaa atgcccaggc agataggggt gggtacctgg
2401 tgaaacccaa ccttaaagct gaagacagtc ccggctaaat cctcatactg aattgagaac
2461 ctgtcttccc atttggtgtg ctttcctccg attgatccca acccttcacc tattttacgt
2521 atacctgccc tttcctaatt ggtttttaca ctgctgtgcc caccttttga gtggtgcctt
2581 tgcatactta caaatcagtc aacgtgtatt cccctattct gagcccataa aagacccaga
2641 ctcagctgca gtgaggagag aaatcaccct gctgtggggg ttggggacca ctccctgcat
2701 cccctctcca ctgagagctg ttcttttgct caataaaatt cttttctacc catcctcaaa
2761 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaa
//