LOCUS BC053655 2540 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens FYVE, RhoGEF and PH domain containing 2, mRNA (cDNA
clone MGC:61693 IMAGE:5755893), complete cds.
ACCESSION BC053655
VERSION BC053655.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2540)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2540)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (09-JUN-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 115 Row: h Column: 9
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 34222232.
FEATURES Location/Qualifiers
source 1..2540
/db_xref="H-InvDB:HIT000053959"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:61693 IMAGE:5755893"
/tissue_type="Blood, adult leukocytes"
/clone_lib="NIH_MGC_118"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2540
/gene="FGD2"
/gene_synonym="ZFYVE4"
/db_xref="GeneID:221472"
/db_xref="HGNC:HGNC:3664"
/db_xref="MIM:605091"
CDS 117..2084
/gene="FGD2"
/gene_synonym="ZFYVE4"
/codon_start=1
/product="FYVE, RhoGEF and PH domain containing 2"
/protein_id="AAH53655.1"
/db_xref="GeneID:221472"
/db_xref="HGNC:HGNC:3664"
/db_xref="MIM:605091"
/translation="MKGASEEKLASVSNLVTVFENSRTPEAAPRGQRLEDVHHRPECR
PPESPGPREKTNVGEAVGSEPRTVSRRYLNSLKNKLSSEAWRKSCQPVTLSGSGTQEP
EKKIVQELLETEQAYVARLHLLDQVFFQELLKTARSSKAFPEDVVRVIFSNISSIYQF
HSQFFLPELQRRLDDWTANPRIGDVIQKLAPFLKMYSEYVKNFERAAELLATWTDKSP
LFQEVLTRIQSSEASGSLTLQHHMLEPVQRIPRYELLLKEYIQKLPAQAPDQADAQKA
LDMIFSAAQHSNAAITEMERLQDLWEVYQRLGLEDDIVDPSNTLLREGPVLKISFRRN
DPMERYLFLFNNMLLYCVPRVIQVGAQFQVRTRIDVAGMKVRELMDAEFPHSFLVSGK
QRTLELQARSQEEMISWMQAFQAAIDQIEKRNETFKAAAQGPEGDIQEQELQSEELGL
RAPQWVRDKMVTMCMRCQEPFNALTRRRHHCRACGYVVCARCSDYRAELKYDDNRPNR
VCLHCYAFLTGNVLPEAKEDKRRGILEKGSSATPDQSLMCSFLQLIGDKWGKSGPRGW
CVIPRDDPLVLYVYAAPQDMRAHTSIPLLGYQVTVGPQGDPRVFQLQQSGQLYTFKAE
TEELKGRWVKAMERAASGWSPSWPNDGDLSD"
BASE COUNT 601 a 744 c 735 g 460 t
ORIGIN
1 acagattcat gggtgattta gcctatctgt cccaggccag cgtggctgag tgtgctggct
61 ggaggcctct ctctctgctt cgagggtagc tgagatccac cccggaaacc ggcaggatga
121 agggggcaag tgaggagaag ctggcatctg tgtccaacct ggtcactgtg tttgagaata
181 gcaggacccc agaagcagca cccagaggcc agaggctaga ggacgtgcat caccgccctg
241 agtgcaggcc tcccgagtcc ccaggaccac gggagaagac gaatgtcggg gaggccgtgg
301 ggtctgagcc caggacagtc agcaggaggt acctgaactc cctgaagaac aagctgtcca
361 gcgaagcctg gaggaaatct tgccagcctg tgaccctctc aggatcgggg acacaggagc
421 cagagaagaa gatcgtccag gagctgctgg agacagagca ggcctatgtg gcgcgcctcc
481 acctgctaga ccaggtgttt ttccaggagc tgctgaagac agcccgcagc agcaaggcct
541 tcccagagga tgtggtcagg gtcatcttct ccaacatctc ctccatctat cagttccatt
601 ctcagttctt cctcccagag ctgcagcggc gcctggacga ctggacagct aacccccgca
661 tcggtgacgt gatccagaag ctggccccct tcctgaagat gtacagtgag tatgtcaaga
721 actttgagcg agcggctgag ctgctggcca cctggaccga caagtctcca ctcttccagg
781 aggttctcac tcgcatccag agcagcgagg cttcgggcag cctgaccctg cagcaccaca
841 tgctggaacc agtgcagaga attccacgtt acgagctgct gctcaaggag tacatccaga
901 agctgccagc ccaggcccca gaccaggccg atgcccagaa agccctggac atgatcttct
961 cagctgccca gcactccaat gcagccatca ctgagatgga gcggctgcag gacctgtggg
1021 aggtgtacca gcgcctgggc ctcgaggacg acatagtaga cccctctaac accctgctcc
1081 gtgagggccc ggtcctcaag atctccttcc gccgcaacga ccccatggag cgctaccttt
1141 tcttgttcaa caacatgctg ctctactgtg tgcccagggt gatccaggtg ggcgcccagt
1201 tccaggtgag gacccgcatc gatgtggccg ggatgaaggt gcgggagctg atggatgctg
1261 agtttcccca ctccttcctg gtgtccggga agcagcgcac cctggagctg caagcccggt
1321 cccaggagga aatgatttcc tggatgcagg ccttccaagc agccattgac caaatcgaga
1381 agcggaatga aaccttcaag gctgcggccc aggggcctga gggagacatc caggagcagg
1441 agctgcagtc tgaggagctg ggcctccggg caccgcagtg ggtccgggac aagatggtga
1501 ccatgtgcat gcgctgccag gagcccttca acgctctgac gcgccgtcgc caccactgcc
1561 gggcctgcgg ctatgtggtg tgtgccaggt gctccgacta ccgggccgaa ctgaaatacg
1621 acgacaacag gcccaaccga gtctgcctcc actgctacgc attcctcact ggaaatgtgc
1681 tgcctgaggc caaggaggac aagaggcggg gcatcctgga gaaagggtcc tcagccacac
1741 ctgaccagag cctgatgtgc agcttcctgc agctcatcgg ggacaagtgg ggcaagagcg
1801 gcccccgggg ctggtgtgtg atccctcggg atgaccccct cgtgctctat gtctatgctg
1861 cccctcagga catgagggct cacacctcca tccccctgct gggctaccag gtgactgttg
1921 ggccccaggg ggaccctcgg gtcttccagc tacagcagtc aggccagctc tacaccttca
1981 aggccgagac ggaggagctg aagggccgct gggtgaaggc catggagcgg gcggccagtg
2041 gctggagccc cagctggccc aacgatgggg acctgtccga ctgagccact gccagccgct
2101 ctcctgccca cctctcccca ccctgaaccc agctcctgcc acagactgac cctgtggcct
2161 cagtgaccca ctgccccaag tggtgctttc agagaattga ttcagccatc tgcgcccagg
2221 ccacgtgtcc cgatctggga ttagaaaata tgggtccatt cctttctaga aaggggacaa
2281 ccaagtgtct cagtttgcct tgcggggagg gggctcctgg gccatgggac ttccagtgct
2341 aaaactggga aagccccagg taaccccgga ctggtggtca ccatagtatg gtttttcatt
2401 tgtatctcct ggggagcttt taaagagtac tggtgaaaaa cacatagtaa attaatttta
2461 aaaatgtaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
2521 aaaaaaaaaa aaaaaaaaaa
//