LOCUS BC053577 2639 bp mRNA linear HUM 16-SEP-2003
DEFINITION Homo sapiens splicing factor 3b, subunit 2, 145kDa, mRNA (cDNA
clone IMAGE:4478742), partial cds.
ACCESSION BC053577
VERSION BC053577.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2639)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2639)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (09-JUN-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 115 Row: a Column: 24.
FEATURES Location/Qualifiers
source 1..2639
/db_xref="H-InvDB:HIT000259295"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:4478742"
/tissue_type="Testis, embryonal carcinoma"
/clone_lib="NIH_MGC_92"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..>2639
/gene="SF3B2"
/gene_synonym="SAP145"
/gene_synonym="SF3b1"
/gene_synonym="SF3B145"
/gene_synonym="SF3b150"
/db_xref="GeneID:10992"
/db_xref="MIM:605591"
CDS 8..>2639
/gene="SF3B2"
/gene_synonym="SAP145"
/gene_synonym="SF3b1"
/gene_synonym="SF3B145"
/gene_synonym="SF3b150"
/codon_start=1
/product="SF3B2 protein"
/protein_id="AAH53577.1"
/db_xref="GeneID:10992"
/db_xref="MIM:605591"
/translation="MATEHPEPPKAELQLPPPPPPGHYGAWAAQELQAKLAEIGAPIQ
GNREELVERLQSYTRQTGIVLNRPVLRGEDGDKAAPPPMSAQLPGIPMPPPPLGLPPL
QPPPPPPPPPPGLGLGFPMAHPPNLGPPPPLRVGEPVALSEEERLKLAQQQAALLMQQ
EERAKQQGDHSLKEHELLEQQKRAAVLLEQERQQEIAKMGTPVPRPPQDMGQIGVRTP
LGPRVAAPVGPVGPTPTVLPMGAPVPRPRGPPPPPGDENREMDDPSVGPKIPQALEKI
LQLKESRQEEMNSQQEEEEMETDARSSLGQSASETEEDTVSVSKKEKNRKRRNRKKKK
KPQRVRGVSSESSGDREKDSTRSRGSDSPAADVEIEYVTEEPEIYEPNFIFFKRIFEA
FKLTDDVKKEKEKEPEKLDKLENSAAPKKKGFEEEHKDSDDDSSDDEQEKKPEAPKLS
KKKLRRMNRFTVAELKQLVARPDVVEMHDVTAQDPKLLVHLKATRNSVPVPRHWCFKR
KYLQGKRGIEKPPFELPDFIKRTGIQEMREALQEKEEQKTMKSKMREKVRPKMGKIDI
DYQKLHDAFFKWQTKPKLTIHGDLYYEGKEFETRLKEKKPGDLSDELRISLGMPVGPN
AHKVPPPWLIAMQRYGPPPSYPNLKIPGLNSPIPESCSFGYHAGGWGKPPVDETGKPL
YGDVFGTNAAEFQTKTEEEEIDRTPWGELEPSDEESSEEEEEEESDEDKPDETGFITP
ADSGLITPGGFSSVPAGMETPELIELRKKKIEEAMDGSETPQLFTVLPEKRTATVGGA
MMGSTHIYDMSTVMSRKGPAPELQGVEVALAPEELELDPMAMTQKYEEHVREQQAQVE
KEDFSDMVAEHAAKQKQKKKK"
misc_feature 77..181
/gene="SF3B2"
/gene_synonym="SAP145"
/gene_synonym="SF3b1"
/gene_synonym="SF3B145"
/gene_synonym="SF3b150"
/note="SAP; Region: SAP domain. The SAP (after SAF-A/B,
Acinus and PIAS) motif is a putative DNA binding domain
found in diverse nuclear proteins"
/db_xref="CDD:pfam02037"
misc_feature 1370..2107
/gene="SF3B2"
/gene_synonym="SAP145"
/gene_synonym="SF3b1"
/gene_synonym="SF3B145"
/gene_synonym="SF3b150"
/note="CUS1; Region: COG5182, CUS1, Splicing factor 3b,
subunit 2 [RNA processing and modification]"
/db_xref="CDD:COG5182"
BASE COUNT 697 a 690 c 789 g 463 t
ORIGIN
1 ggctaagatg gcgacggagc atcccgagcc tcccaaagca gaattgcagc tgccgccgcc
61 gccacctcca ggccactatg gcgcctgggc tgcccaggag cttcaggcca agttggcaga
121 gatcggagct ccgatccagg gtaatcgcga ggagctggtg gagcggctgc agagctacac
181 ccgccagact ggcatcgtgc tgaatcggcc ggttttgaga ggggaagatg gggacaaagc
241 cgctccacct cccatgtcgg cacagctccc tggaattccc atgccaccac cacctttggg
301 actcccccct ctgcagcctc ctccgccacc cccaccacct ccaccaggcc ttggccttgg
361 ctttcctatg gcccacccac caaatttggg gcccccgcct cctctccgtg tgggtgagcc
421 agtggcactg tcagaggagg agcggctgaa gttggctcag cagcaggcgg cattgctgat
481 gcagcaggag gagcgtgcca agcagcaggg agatcattcg ctgaaggaac atgagctctt
541 ggagcagcag aagcgggcag ctgtgttact ggagcaggaa cgacagcagg agattgccaa
601 gatgggcacc ccagtccctc ggcccccaca agacatgggc cagattggtg tgcgcactcc
661 tctgggtcct cgagtagctg ctccagtggg cccagtgggc cccactccta cagttttgcc
721 catgggagcc cctgttcccc ggcctcgtgg tcccccaccg ccccctggag atgagaacag
781 agagatggat gacccctctg tgggccccaa gatcccccag gctttggaga agatcctgca
841 gctgaaggag agccgccagg aagagatgaa ttctcagcag gaggaagagg aaatggaaac
901 agatgctcgc tcgtccctgg gccagtcagc gtcagagact gaggaggaca cagtgtccgt
961 atctaaaaag gagaaaaacc ggaagcgtag gaaccgaaag aagaagaaaa agccccagcg
1021 ggtgcgaggg gtgtcctctg agagctctgg ggaccgggag aaagactcaa cccggtcccg
1081 tggctctgat tccccagcag ctgatgttga gattgagtat gtgactgaag aacctgaaat
1141 ttacgagccc aactttatct tctttaagag gatctttgag gcttttaagc tcactgatga
1201 tgtgaagaag gagaaagaga aggagccaga gaaacttgac aaactggaga actctgcagc
1261 ccccaagaag aagggatttg aagaggagca caaggacagt gatgatgaca gcagtgatga
1321 cgagcaggaa aagaagccag aagcccccaa gctgtccaag aagaagttgc gccgaatgaa
1381 ccgcttcact gtggctgaac tcaagcagct ggtggctcgg cccgatgtcg tggagatgca
1441 cgatgtgaca gcgcaggacc ctaagctctt ggttcacctc aaggccactc ggaactctgt
1501 gcctgtgcca cgccactggt gttttaagcg caaatacctg cagggcaaac ggggcattga
1561 gaagcccccc ttcgagctgc cagacttcat caaacgcaca ggcatccagg agatgcgaga
1621 ggccctgcag gagaaggaag aacagaagac catgaagtca aaaatgcgag agaaagttcg
1681 gcctaagatg ggcaaaattg acatcgacta ccagaaactg catgatgcct tcttcaagtg
1741 gcagaccaag ccaaagctga ccatccatgg ggacctgtac tatgagggga aggagttcga
1801 gacacgactg aaggagaaga agccaggaga tctgtctgat gagctaagga tttccttggg
1861 gatgccagta ggaccaaatg cccacaaggt ccctccccca tggctgattg ccatgcagcg
1921 atatggacca cccccatcgt atcccaacct gaaaatccct gggctgaact cgcccatccc
1981 tgagagctgt tcctttgggt accatgctgg tggctggggc aaacctccag tggatgagac
2041 tgggaaaccg ctctatgggg acgtgtttgg aaccaatgct gctgaatttc agaccaagac
2101 tgaggaagaa gagattgatc ggaccccttg gggggaactg gaaccatctg atgaagaatc
2161 ctcagaagaa gaggaagagg aagaaagtga tgaagacaaa ccagatgaga caggctttat
2221 tacccctgca gacagtggcc ttatcactcc tggaggcttt tcatcagtgc ctgctggaat
2281 ggagacccct gaactcattg agctgaggaa gaagaagatt gaggaggcga tggacggaag
2341 tgagacacct cagctcttca ctgtgttgcc agagaagaga acagccactg ttggaggggc
2401 catgatggga tcaacccaca tttatgacat gtccacggtt atgagccgga agggcccggc
2461 tcctgagctg caaggtgtgg aagtggcgct ggcgcctgaa gagttggagc tggatcctat
2521 ggccatgacc cagaagtatg aggagcatgt gcgggagcag caggctcaag tagagaagga
2581 ggacttcagt gacatggtgg ctgagcacgc tgccaaacag aagcaaaaaa aaaaaaaaa
//