LOCUS BC053536 2990 bp mRNA linear HUM 07-OCT-2003
DEFINITION Homo sapiens renal tumor antigen, mRNA (cDNA clone MGC:61453
IMAGE:5175851), complete cds.
ACCESSION BC053536
VERSION BC053536.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2990)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2990)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (09-JUN-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 115 Row: c Column: 13
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 7657497.
FEATURES Location/Qualifiers
source 1..2990
/db_xref="H-InvDB:HIT000053904"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:61453 IMAGE:5175851"
/tissue_type="Brain, Lung, Testis, adult, pooled whole"
/clone_lib="NIH_MGC_115"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2990
/gene="RAGE"
/gene_synonym="MOK"
/gene_synonym="RAGE1"
/db_xref="GeneID:5891"
/db_xref="MIM:605762"
CDS 209..904
/gene="RAGE"
/gene_synonym="MOK"
/gene_synonym="RAGE1"
/codon_start=1
/product="RAGE protein"
/protein_id="AAH53536.1"
/db_xref="GeneID:5891"
/db_xref="MIM:605762"
/translation="MKNYKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQRFESIEQ
VNNLREIQALRRLNPHPNILMLHEVVFDRKSGSLALICELMDMNIYELIRGRRYPLSE
KKIMHYMYQLCKSLDHIHRNGIFHRDVKPENILIKQDVLKLGDFGSCRSVYSKQPYTE
YISTRWYRAPECLLTDGFYTYKMDLWSAGCVFYEIASLQPLFPGVNELDQISKIHDVI
GTPAQKILTKFKQ"
misc_feature 218..850
/gene="RAGE"
/gene_synonym="MOK"
/gene_synonym="RAGE1"
/note="S_TKc; Region: Serine/Threonine protein kinases,
catalytic domain"
/db_xref="CDD:smart00220"
BASE COUNT 811 a 734 c 753 g 692 t
ORIGIN
1 ctcatggcgt tcagggcctg acggttgcta gggtgacagg gacacaacat ggcggcggga
61 tctctaacgc tctccttcga gggaccacca cggagatcct agtgcgggac cccgcctcag
121 ggaagtggaa agcaggggga caaccttcct gcttctttct tttccgtcca gtgtcggcaa
181 ggggttgtca ccggcttccg catccaagat gaagaactat aaagcaattg gcaaaatagg
241 agagggaacg ttttctgaag ttatgaagat gcaaagcctg agagatggaa actactatgc
301 atgtaaacaa atgaagcagc gctttgaaag tattgagcaa gtcaacaacc tacgagagat
361 ccaagcactg aggcgcctga atccgcaccc aaacattctt atgttgcatg aagtggtttt
421 tgacagaaaa tctggttctc ttgcactaat atgtgaactt atggacatga atatttatga
481 gctaatacga gggagaagat acccattatc agaaaaaaaa attatgcact atatgtacca
541 gttatgtaag tccctggatc atattcacag aaatggaata tttcacagag atgtaaaacc
601 agaaaatata ctaataaagc aggatgtcct gaaattaggg gactttggct cctgccggag
661 tgtctattcc aagcagccgt acacggaata catctccacc cgctggtacc gggccccgga
721 gtgtctcctc actgatgggt tctacacgta caagatggac ctgtggagcg ccggctgtgt
781 gttctacgag atcgccagtc tgcagcccct ctttcctgga gtaaatgaac tggaccaaat
841 ctcaaaaatc cacgatgtca tcggcacacc cgctcagaag atcctcacca agttcaaaca
901 gtaagtattg tgttctgaga gtggatgtgg acccactccc ctgctaggac ctgcagcagg
961 gcaagcccct ccctgtgcct ccctcaaacc cctctcagga gctcctttgg ctgactacag
1021 gggttcaagt tcacttgagg gccagtgagt ggctgctcag acagagccca tcactttaag
1081 tggtctcaaa ggtgagctct tccttgagca tcacagaaag atttgtcaca ggctttctga
1141 gggctgggga gtcaggctgt gttccctgag taatttaaac aggacttaga agcctttggg
1201 tggaaacgtt ccccaagcac agagcatagg tggtgagggc tttctgcagc cctccacagc
1261 cctgctggcg ggaccgacgc ctggaagagg tgttcccgga ctcttagggt cattctggtg
1321 aagctgaggc tgggagttgg gacttcccag ggagggcctg tgggctgagg ggcaagtagc
1381 acccagcggc ccccacatcc cagggaggga gaaggtggca accattttgg actcttcttt
1441 ttttgttaaa ttttatttca ttcttctcat gtgggaaggt gatattaatc ttttatagga
1501 aaggtagttt tcttacattt ttagcataac agatcccccc ctttataata gactattttt
1561 aaatagattt ttttaagagc agttttaggt ttccatagag ccctgtcccc atgtgcacac
1621 agcctcccct gtcgtcagca cctgcctcga gtggtgtgtt tattatggtc gatgaaccgt
1681 ggatatctca ttactacaca gagcccatca tttacatcag gggtccctct tggtggtgca
1741 cgttctgtgg gctgggacag gtgtagactc tgcagtcata aaccattccc caccacacag
1801 ggcccttagt tgtgacagtg gaccaccggt gcgctcagtg acagcatgac catttattat
1861 cattgggttt ttaatacagg tcgagagcta tgaattttga ttttcctttt aaaaagggat
1921 caggaatacc tctactaaca accaatttgt ccccacaatg cctctccctc ctgcacgcaa
1981 tggtggccta tgatcccgat gagagaatcg ccgcccacca ggccctgcag cacccctact
2041 tccaagaaca gaggaaaaca gagaagcggg ctctgggcag ccacagaaaa gctggctttc
2101 cggagcaccc tgtggcaccg gaaccactca gtaacagctg ccagatttcc aaggagggca
2161 gaaagcagaa acagtcccta aagcaagagg aggaccgtcc caagagacga ggaccggcct
2221 atgtcatgga actgcccaaa ctaaagcttt cgggagtggt cagactgtcg tcttactcca
2281 gccccacgct gcagtccgtg cttggatctg gaacaaatgg aagagtgccg gtgctgagac
2341 ccttgaagtg catccctgcg agcaagaaga cagatccgca gaaggacctt aagcctgccc
2401 cgcagcagtg tcgcctgccc accatagtgc ggaaaggcgg aagataactg agcagcaccg
2461 tcgtctcgac ttcggaggca acaccaagcc cgaccgggcc aggcctgggt gatctgctgc
2521 tgagacgcca cggagggctg gggatgcgcc tgcgtccgtt tcgcgctggc cggggctctg
2581 ggtgctgccc tgcgccctgc cgcacccgcg gcccgcgcag ctgcctagga tgttctgggc
2641 taatatactt gtaaaaccac cgcattctag ggttttcttt cattttcgtt aagaatttgg
2701 ggcaggaaat actttgtaac tttgtatatg aatcaaaaca aacgagcagg catttctgtg
2761 atgtgttggg cgtggttgga aggtgggttc tgcgtgtccc ttcccagcgc tgctggtcag
2821 tcgtggagcg ccatcatgtc ttaccagtga cgctgctgac acccctgact tttattaaag
2881 aataagctgt cgttacaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
2941 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
//