LOCUS BC053365 1998 bp mRNA linear HUM 08-NOV-2004
DEFINITION Homo sapiens ribosomal protein S6 kinase, 70kDa, polypeptide 1,
mRNA (cDNA clone MGC:61512 IMAGE:6142009), complete cds.
ACCESSION BC053365
VERSION BC053365.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1998)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1998)
AUTHORS Director MGC Project.
TITLE Direct Submission
JOURNAL Submitted (02-JUN-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 115 Row: k Column: 19
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 4506736.
FEATURES Location/Qualifiers
source 1..1998
/db_xref="H-InvDB:HIT000053886"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:61512 IMAGE:6142009"
/tissue_type="Eye, retinoblastoma"
/clone_lib="NIH_MGC_67"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..1998
/gene="RPS6KB1"
/gene_synonym="p70(S6K)-alpha"
/gene_synonym="p70-alpha"
/gene_synonym="p70-S6K"
/gene_synonym="PS6K"
/gene_synonym="S6K"
/gene_synonym="S6K1"
/gene_synonym="STK14A"
/db_xref="GeneID:6198"
/db_xref="MIM:608938"
CDS 42..1397
/gene="RPS6KB1"
/gene_synonym="p70(S6K)-alpha"
/gene_synonym="p70-alpha"
/gene_synonym="p70-S6K"
/gene_synonym="PS6K"
/gene_synonym="S6K"
/gene_synonym="S6K1"
/gene_synonym="STK14A"
/codon_start=1
/product="RPS6KB1 protein"
/protein_id="AAH53365.1"
/db_xref="GeneID:6198"
/db_xref="MIM:608938"
/translation="MRRRRRRDGFYPAPDFRDREAEDMAGVFDIDLDQPEDAGSEDEL
EEGGQLNESMDHGGVGPYELGMEHCEKFEISETSVNRGPEKIRPECFELLRVLGKGGY
GKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIY
AFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRD
LKPENIMLNHQGHVKLTDFGLCKESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDW
WSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPPYLTQEARDLLKKLLKRNAAS
RLGAGPGDAGEVQAHPFFRHINWEELLARKVEPPFKPLLQSEEDVSQFDSKFTRQTPV
DSPDDSTLSESANQVFLGFTYVAPSVLESVKEKFSFEPKIRSPRRFIGSPRTPVSTAM
C"
BASE COUNT 622 a 378 c 471 g 527 t
ORIGIN
1 gtggcggcag cggctgtggt ggctgcggcg ggtccgggcc catgaggcga cgaaggaggc
61 gggacggctt ttacccagcc ccggacttcc gagacaggga agctgaggac atggcaggag
121 tgtttgacat agacctggac cagccagagg acgcgggctc tgaggatgag ctggaggagg
181 ggggtcagtt aaatgaaagc atggaccatg ggggagttgg accatatgaa cttggcatgg
241 aacattgtga gaaatttgaa atctcagaaa ctagtgtgaa cagagggcca gaaaaaatca
301 gaccagaatg ttttgagcta cttcgggtac ttggtaaagg gggctatgga aaggtttttc
361 aagtacgaaa agtaacagga gcaaatactg ggaaaatatt tgccatgaag gtgcttaaaa
421 aggcaatgat agtaagaaat gctaaagata cagctcatac aaaagcagaa cggaatattc
481 tggaggaagt aaagcatccc ttcatcgtgg atttaattta tgcctttcag actggtggaa
541 aactctacct catccttgag tatctcagtg gaggagaact atttatgcag ttagaaagag
601 agggaatatt tatggaagac actgcctgct tttacttggc agaaatctcc atggctttgg
661 ggcatttaca tcaaaagggg atcatctaca gagacctgaa gccggagaat atcatgctta
721 atcaccaagg tcatgtgaaa ctaacagact ttggactatg caaagaatct attcatgatg
781 gaacagtcac acacacattt tgtggaacaa tagaatacat ggcccctgaa atcttgatga
841 gaagtggcca caatcgtgct gtggattggt ggagtttggg agcattaatg tatgacatgc
901 tgactggagc acccccattc actggggaga atagaaagaa aacaattgac aaaatcctca
961 aatgtaaact caatttgcct ccctacctca cacaagaagc cagagatctg cttaaaaagc
1021 tgctgaaaag aaatgctgct tctcgtctgg gagctggtcc tggggacgct ggagaagttc
1081 aagctcatcc attctttaga cacattaact gggaagaact tctggctcga aaggtggagc
1141 ccccctttaa acctctgttg caatctgaag aggatgtaag tcagtttgat tccaagttta
1201 cacgtcagac acctgtcgac agcccagatg actcaactct cagtgaaagt gccaatcagg
1261 tctttctggg ttttacatat gtggctccat ctgtacttga aagtgtgaaa gaaaagtttt
1321 cctttgaacc aaaaatccga tcacctcgaa gatttattgg cagcccacga acacctgtca
1381 gtactgctat gtgctaagct taactggaag ccttggaatg ggcataagtt gtatgtccta
1441 catttcatca ttgtcccggg cctgcattgc actggaaaaa aaaatcgcca cctgttctta
1501 caccagtatt tggttcaaga caccaaatgt cttcagccca tggctgaaga acaacagaag
1561 agagtcagga taaaaaatac atactgtggt cggcaaggtg agggagatag ggatatccag
1621 gggaagaggg tgttgctgtg gcccactctc tgtctaatct ctttacagca aattggtaag
1681 attttcagtt ttacttcttt ctactgtttc tgctgtctac cttccttata tttttttcct
1741 caacagtttt aaaaagaaaa aaaggtctat ttttttttct cctatacttg ggctacattt
1801 tttgattgta aaaatatttg atggcctttt gatgaatgtc ttccacagta aagaaaactt
1861 agtggcttaa tttaggaaac atgttaacag gacactatgt ttttgaaatt gtaacaaaat
1921 ctacataaat gatttacagg ttaaaagaat aaaaataaag gtaactttac ctttcttaaa
1981 tataaaaaaa aaaaaaaa
//