LOCUS BC053343 1997 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens karyopherin alpha 2 (RAG cohort 1, importin alpha 1),
mRNA (cDNA clone MGC:61578 IMAGE:4450470), complete cds.
ACCESSION BC053343
VERSION BC053343.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1997)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1997)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (02-JUN-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 115 Row: a Column: 21
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 62388891.
FEATURES Location/Qualifiers
source 1..1997
/db_xref="H-InvDB:HIT000053877_03"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:61578 IMAGE:4450470"
/tissue_type="Liver, adenocarcinoma"
/clone_lib="NIH_MGC_90"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..1997
/gene="KPNA2"
/gene_synonym="IPOA1"
/gene_synonym="QIP2"
/gene_synonym="SRP1alpha"
/db_xref="GeneID:3838"
/db_xref="HGNC:HGNC:6395"
/db_xref="MIM:600685"
CDS 119..1708
/gene="KPNA2"
/gene_synonym="IPOA1"
/gene_synonym="QIP2"
/gene_synonym="SRP1alpha"
/codon_start=1
/product="karyopherin alpha 2 (RAG cohort 1, importin
alpha 1)"
/protein_id="AAH53343.1"
/db_xref="GeneID:3838"
/db_xref="HGNC:HGNC:6395"
/db_xref="MIM:600685"
/translation="MSTNENANTPAARLHRFKNKGKDSTEMRRRRIEVNVELRKAKKD
DQMLKRRNVSSFPDDATSPLQENRNNQGTVNWSVDDIVKGINSSNVENQLQATQAARK
LLSREKQPPIDNIIRAGLIPKFVSFLGRTDCSPIQFESAWALTNIASGTSEQTKAVVD
GGAIPAFISLLASPHAHISEQAVWALGNIAGDGSVFRDLVIKYGAVDPLLALLAVPEM
SSLACGYLRNLTWTLSNLCRNKNPAPPIDAVEQILPTLVRLLHHDDPEVLADTCWAIS
YLTDGPNERIGMVVKTGVVPQLVKLLGASELPIVTPALRAIGNIVTGTDEQTQVVIDA
GALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLVPFLVSVLSKADFK
TQKEAVWAVTNYTSGGTVEQIVYLVHCGIIEPLMNLLTAKDTKIILVILDAISNIFQA
AEKLGETEKLSIMIEECGGLDKIEALQNHENESVYKASLSLIEKYFSVEEEEDQNVVP
ETTSEGYTFQVQDGAPGTFNF"
BASE COUNT 574 a 449 c 433 g 541 t
ORIGIN
1 gagctgagtc gaggtggacc ctttgaacgc agtcgcccta cagccgctga ttccccccgc
61 atcgcctccc gtggaagccc aggcccgctt cgcagctttc tccctttgtc tcataaccat
121 gtccaccaac gagaatgcta atacaccagc tgcccgtctt cacagattca agaacaaggg
181 aaaagacagt acagaaatga ggcgtcgcag aatagaggtc aatgtggagc tgaggaaagc
241 taagaaggat gaccagatgc tgaagaggag aaatgtaagc tcatttcctg atgatgctac
301 ttctccgctg caggaaaacc gcaacaacca gggcactgta aattggtctg ttgatgacat
361 tgtcaaaggc ataaatagca gcaatgtgga aaatcagctc caagctactc aagctgccag
421 gaaactactt tccagagaaa aacagccccc catagacaac ataatccggg ctggtttgat
481 tccgaaattt gtgtccttct tgggcagaac tgattgtagt cccattcagt ttgaatctgc
541 ttgggcactc actaacattg cttctgggac atcagaacaa accaaggctg tggtagatgg
601 aggtgccatc ccagcattca tttctctgtt ggcatctccc catgctcaca tcagtgaaca
661 agctgtctgg gctctaggaa acattgcagg tgatggctca gtgttccgag acttggttat
721 taagtacggt gcagttgacc cactgttggc tctccttgca gttcctgaga tgtcatcttt
781 agcatgtggc tacttacgta atcttacctg gacactttct aatctttgcc gcaacaagaa
841 tcctgcaccc ccgatagatg ctgttgagca gattcttcct accttagttc ggctcctgca
901 tcatgatgat ccagaagtgt tagcagatac ctgctgggct atttcctacc ttactgatgg
961 tccaaatgaa cgaattggca tggtggtgaa aacaggagtt gtgccccaac ttgtgaagct
1021 tctaggagct tctgaattgc caattgtgac tcctgcccta agagccatag ggaatattgt
1081 cactggtaca gatgaacaga ctcaggttgt gattgatgca ggagcactcg ccgtctttcc
1141 cagcctgctc accaacccca aaactaacat tcagaaggaa gctacgtgga caatgtcaaa
1201 catcacagcc ggccgccagg accagataca gcaagttgtg aatcatggat tagtcccatt
1261 ccttgtcagt gttctctcta aggcagattt taagacacaa aaggaagctg tgtgggccgt
1321 gaccaactat accagtggtg gaacagttga acagattgtg taccttgttc actgtggcat
1381 aatagaaccg ttgatgaacc tcttaactgc aaaagatacc aagattattc tggttatcct
1441 ggatgccatt tcaaatatct ttcaggctgc tgagaaacta ggtgaaactg agaaacttag
1501 tataatgatt gaagaatgtg gaggcttaga caaaattgaa gctctacaaa accatgaaaa
1561 tgagtctgtg tataaggctt cgttaagctt aattgagaag tatttctctg tagaggaaga
1621 ggaagatcaa aacgttgtac cagaaactac ctctgaaggc tacactttcc aagttcagga
1681 tggggctcct gggaccttta acttttagat catgtagctg agacataaat ttgttgtgta
1741 ctacgtttgg tattttgtct tattgtttct ctactaagaa ctctttctta aatgtggttt
1801 gttactgtag cactttttac actgaaacta tacttgaaca gttccaactg tacatacata
1861 ctgtatgaag cttgtcctct gactaggttt ctaatttcta tgtggaattt cctatcttgc
1921 agcatcctgt aaataaacat tcaagtccac ccttttcttg acttcaaaaa aaaaaaaaaa
1981 aaaaaaaaaa aaaaaaa
//