LOCUS BC053319 2956 bp mRNA linear HUM 19-JUN-2006
DEFINITION Homo sapiens sialic acid binding Ig-like lectin 8, mRNA (cDNA clone
MGC:59785 IMAGE:6302572), complete cds.
ACCESSION BC053319
VERSION BC053319.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2956)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2956)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (02-JUN-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Dr. Mark Watson
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 47 Row: k Column: 1
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 7657571.
FEATURES Location/Qualifiers
source 1..2956
/db_xref="H-InvDB:HIT000053870"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:59785 IMAGE:6302572"
/tissue_type="Spleen"
/clone_lib="NIH_MGC_113"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2956
/gene="SIGLEC8"
/gene_synonym="SAF2"
/gene_synonym="SIGLEC-8"
/gene_synonym="SIGLEC8L"
/db_xref="GeneID:27181"
/db_xref="HGNC:HGNC:10877"
/db_xref="MIM:605639"
CDS 57..1556
/gene="SIGLEC8"
/gene_synonym="SAF2"
/gene_synonym="SIGLEC-8"
/gene_synonym="SIGLEC8L"
/codon_start=1
/product="sialic acid binding Ig-like lectin 8"
/protein_id="AAH53319.1"
/db_xref="GeneID:27181"
/db_xref="HGNC:HGNC:10877"
/db_xref="MIM:605639"
/translation="MLLLLLLLPLLWGTKGMEGDRQYGDGYLLQVQELVTVQEGLCVH
VPCSFSYPQDGWTDSDPVHGYWFRAGDRPYQDAPVATNNPDREVQAETQGRFQLLGDI
WSNDCSLSIRDARKRDKGSYFFRLERGSMKWSYKSQLNYKTKQLSVFVTALTHRPDIL
ILGTLESGHPRNLTCSVPWACKQGTPPMISWIGASVSSPGPTTARSSVLTLTPKPQDH
GTSLTCQVTLPGTGVTTTSTVRLDVSYPPWNLTMTVFQGDATASTALGNGSSLSVLEG
QSLRLVCAVNSNPPARLSWTRGSLTLCPSRSSNPGLLELPRVHVRDEGEFTCRAQNAQ
GSQHISLSLSLQNEGTGTSRPVSQVTLAAVGGAGATALAFLSFCIIFIIVRSCRKKSA
RPAAGVGDTGMEDAKAIRGSASQGPLTESWKDGNPLKKPPPAVAPSSGEEGELHYATL
SFHKVKPQDPQGQEATDSEYSEIKIHKRETAETQACLRNHNPSSKEVRG"
BASE COUNT 689 a 825 c 745 g 697 t
ORIGIN
1 gaagaaccct gaggaacaga cgttccctgg cggccctggc gccttcaaac ccagacatgc
61 tgctgctgct gctgctgctg cccctgctct gggggacaaa ggggatggag ggagacagac
121 aatatgggga tggttacttg ctgcaagtgc aggagctggt gacggtgcag gagggcctgt
181 gtgtccatgt gccctgctcc ttctcctacc cccaggatgg ctggactgac tctgacccag
241 ttcatggcta ctggttccgg gcaggagaca gaccatacca agacgctcca gtggccacaa
301 acaacccaga cagagaagtg caggcagaga cccagggccg attccaactc cttggggaca
361 tttggagcaa cgactgctcc ctgagcatca gagacgccag gaagagggat aaggggtcat
421 atttctttcg gctagagaga ggaagcatga aatggagtta caaatcacag ttgaattaca
481 aaactaagca gctgtctgtg tttgtgacag ccctgaccca taggcctgac atcctcatcc
541 tagggaccct agagtctggc caccccagga acctgacctg ctctgtgccc tgggcctgta
601 agcaggggac accccccatg atctcctgga ttggggcctc cgtgtcctcc ccgggcccca
661 ctactgcccg ctcctcagtg ctcaccctta ccccaaagcc ccaggaccac ggcaccagcc
721 tcacctgtca ggtgaccttg cctgggacag gtgtgaccac gaccagtacc gtccgcctcg
781 atgtgtccta ccctccttgg aacttgacca tgactgtctt ccaaggagat gccacagcat
841 ccacagccct gggaaatggc tcatctcttt cagtccttga gggccagtct ctgcgcctgg
901 tctgtgctgt caacagcaat ccccctgcca ggctgagctg gacccggggg agcctgaccc
961 tgtgcccctc acggtcctca aaccctgggc tgctggagct gcctcgagtg cacgtgaggg
1021 atgaagggga attcacctgc cgagctcaga acgctcaggg ctcccagcac atttccctga
1081 gcctctccct gcagaatgag ggcacaggca cctcaagacc tgtatcacaa gtgacactgg
1141 cagcagtcgg gggagctgga gccacagccc tggccttcct gtccttctgc atcatcttca
1201 tcatagtgag gtcctgcagg aagaaatcgg caaggccagc agcgggcgtg ggggatacag
1261 gcatggaaga tgcaaaggcc atcaggggct cggcctctca gggacccctg actgaatcct
1321 ggaaagatgg caaccccctg aagaagcctc ccccagctgt tgccccctcg tcaggggagg
1381 aaggagagct ccattatgca accctcagct tccataaagt gaagcctcag gacccgcagg
1441 gacaggaggc cactgacagt gaatactcgg agatcaagat ccacaagcga gaaactgcag
1501 agactcaggc ctgtttgagg aatcacaacc cctccagcaa agaagtcaga ggctgattct
1561 catagaacaa gaaccctcta gagccccatg ctatgcagta ggtcaccagg gctccctcct
1621 cctgtctaac caaaacttgg accaatgtct cccctttccc cggctaccag ggacccatcc
1681 ctgcctctag cttctactac ccaccattct cctctcgacc tctctgaggt tgactatttt
1741 agattccaca tagagatgag gtcatgtggt acttgcctct ctgtgtgtgg ctcattttac
1801 acaaaaaaat atcccctagg ttcatccatg ttctctcaaa tgacagaatc aagcactgaa
1861 tatttttttt tctttgagag atggagtttc gctctgttgc ccaggctgga gtgcagtggt
1921 tcaatctctg ctcactgcaa cctccacctc ctgggttcaa acgattctcc tgcctcagct
1981 tcccaagtag ctggtactac aggcgtgtgt caccacgccc agctaatttt tgtatttttt
2041 agtagagacg gggtttcact ataagtgggc caggctagtc tcaaactcct gacctcaagt
2101 gatctgcctg ccttggcctc ccaaagtgct gggatttcag gcatgagcca ccgcacccag
2161 cttgcattga atattttcaa ggagctaaaa gaagatttta aatggtctca caaaaacaga
2221 taaatatttg cacagatggg tgtgctaatc attgtgcctt gatggttcca cgatgtatcc
2281 gggtgtggaa atctcactgg gtctctctca aggccactcg gctactcagg acagggctgg
2341 aatttaaagc ctgtccgatt ctgaggtctc ttctctcatc tagcactgag tcaagcaatc
2401 agcaggctgg gcacccctta gccataagtt ttcaggaaat aaattccttg agggcattga
2461 cttttacaaa agagggagca gcaatggcct agagtctcag gaacaagaca ggtgcactga
2521 ggagatgaag gccgggaccc cctgcccaac ctgtatggcg ggtctgtact tattttgttt
2581 acccccaatt taaaacgttt ttttttattg caggttgttt gtttgatatg gtttggctgt
2641 gtccccaccc aaatcttatc tagaattgta atcagaatta taatccccat gtgttggggg
2701 agggacctgg tgggaggtga taggatcatg ggggtggttc ccccatgctg ttctgatagt
2761 gagtgagtta tcacgagatc tgatggtttt gtaagtggtg gtttcccctg ctcttctctc
2821 ttgcctgcca ccatgtaaga tgtgcctggt tccccttccg ccatgattgt aagtttcctg
2881 aggcctcctc cgccatgtgg aactgtgagt caattacacc tctttcattt ataaattaaa
2941 aaaaaaaaaa aaaaaa
//