LOCUS BC052967 1681 bp mRNA linear HUM 16-SEP-2003
DEFINITION Homo sapiens GRP1 (general receptor for phosphoinositides
1)-associated scaffold protein, mRNA (cDNA clone IMAGE:5588584),
partial cds.
ACCESSION BC052967
VERSION BC052967.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1681)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1681)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (02-JUN-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Invitrogen
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 98 Row: a Column: 15.
FEATURES Location/Qualifiers
source 1..1681
/db_xref="H-InvDB:HIT000259240"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:5588584"
/tissue_type="Ovary, pooled from 3 adults"
/clone_lib="NIH_MGC_125"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene <1..1681
/gene="GRASP"
/db_xref="GeneID:160622"
CDS <1..947
/gene="GRASP"
/codon_start=3
/product="GRASP protein"
/protein_id="AAH52967.1"
/db_xref="GeneID:160622"
/translation="KGSGFRWKNLSQSPEQQRKVLTLEKEDNQTFGFEIQTYGLHHRE
EQRVEMVTFVCRVHESSPAQLAGLTPGDTIASVNGLNVEGIRHREIVDIIKASGNVLR
LETLYGTSIRKAELEARLQYLKQTLYEKWGEYRSLMVQEQRLVHGLVVKDPSIYDTLE
SVRSCLYGAGLLPGSLPFGPLLAVPGRPRGGARRARGDADDAVYHTCFFGDSEPPALP
PPPPPARAFGPGPAETPAVGPGPGPRAALSRSASVRCAGPGGGGGGGAPGALWTEARE
QALCGPGLRKTKYRSFRRRLLKFIPGLNRSLEEEESQL"
misc_feature 51..326
/gene="GRASP"
/note="PDZ; Region: Domain present in PSD-95, Dlg, and
ZO-1/2. Also called DHR (Dlg homologous region) or GLGF
(relatively well conserved tetrapeptide in these domains).
Some PDZs have been shown to bind C-terminal polypeptides"
/db_xref="CDD:smart00228"
BASE COUNT 331 a 514 c 552 g 284 t
ORIGIN
1 gaaagggctc aggattccgc tggaagaatc tcagccagag tcctgaacag cagcggaaag
61 tgctgacgtt ggagaaggag gataaccaga ccttcggctt tgagatccag acttatggcc
121 ttcaccaccg ggaggagcag cgtgtggaaa tggtgacctt tgtctgccga gttcatgagt
181 ctagccctgc ccagctggct gggctcacac caggggacac catcgccagc gtcaatggcc
241 tgaatgtgga aggcatccgg catcgagaga ttgtggacat cattaaggcg tcaggcaatg
301 ttctcagact ggaaactcta tatgggacat caattcggaa ggcagaactg gaggctcgtc
361 tgcagtacct gaagcaaacc ctgtatgaga agtggggaga gtacaggtcc ctaatggtgc
421 aggagcagcg gctggtgcat ggcctggtgg tgaaggaccc cagcatctac gacacgctgg
481 agtcggtgcg ctcctgcctc tacggcgcgg gcctgctccc gggctcgctg cccttcgggc
541 ctctgctcgc cgtgcccggg cgtccccgcg gaggcgcccg acgggccagg ggcgacgccg
601 acgacgccgt ctaccacacg tgcttcttcg gggactccga gccgccggcg ctgccgcccc
661 cgccgccccc ggcccgcgcc ttcggcccgg gccccgccga gacccctgcc gtggggccgg
721 gccctgggcc gcgggccgcg ctgagccgca gcgccagtgt gcggtgcgcg ggccctggcg
781 ggggcggagg cgggggcgcg ccgggcgcgc tctggactga ggctcgcgag caggccctat
841 gcggccccgg cctgcgcaaa accaagtacc gcagcttccg ccggcggctg ctcaagttca
901 tccccggact caaccgctcc ctggaggagg aggagagcca gctgtagggg cgggggcggg
961 cagggaggta tttatttatt tattcgcaac agccagcgct aaaagagggg gaggccgagc
1021 caagaggacc ccaggagccc agagcagcgg gagagggtcc ttcctagcct cggcccgccg
1081 ggtcggttcc tggctggtgt ctgctgaggg agtggggggc ccagcccctt ctcttctccc
1141 ccgccaaacc acagtgggag ctggggcagg gggagagcca ggcaatcggg ggccaaagat
1201 gggggtgctc gcctacagtc tgcatctgta gtgccttgtg gggtatccag gaacaccctc
1261 ccagcagggg atgggaaccc tgtcccatga agccctctcc tcagctttac ttgctccccc
1321 gcccttagcc ttggggagaa atggcccgtg gtgggctgac cccccaccct ccacacacac
1381 agttccatga cccagcgggc ccccaggggc atcaggtgct ggtcctcctc cctcctggcc
1441 tcgaccccta agggcttcgc ccctcccagg ggcctgtaac taagtcgggt cctgccaggc
1501 agggggcctg tgttctgtgc cccttgggag acaggaactg gcgagttcag gtggggtggg
1561 gacagcacag actgttccac cgttgtgcat attgttgctt ctgaaccaca aactgtataa
1621 atggatggtt ttttgcaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
1681 a
//