LOCUS BC052805 2579 bp mRNA linear HUM 08-OCT-2003
DEFINITION Homo sapiens erythrocyte membrane protein band 4.9 (dematin), mRNA
(cDNA clone MGC:59859 IMAGE:6269658), complete cds.
ACCESSION BC052805
VERSION BC052805.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2579)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2579)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (27-MAY-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: CGAP (Stanford)
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 47 Row: h Column: 2
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 4503580.
FEATURES Location/Qualifiers
source 1..2579
/db_xref="H-InvDB:HIT000053829"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:59859 IMAGE:6269658"
/tissue_type="Liver, hepatocellular carcinoma"
/clone_lib="NIH_MGC_100"
/lab_host="DH10B"
/note="Vector: pOTB7"
gene 1..2579
/gene="EPB49"
/gene_synonym="DEMATIN"
/gene_synonym="DMT"
/db_xref="GeneID:2039"
/db_xref="MIM:125305"
CDS 314..1465
/gene="EPB49"
/gene_synonym="DEMATIN"
/gene_synonym="DMT"
/codon_start=1
/product="EPB49 protein"
/protein_id="AAH52805.1"
/db_xref="GeneID:2039"
/db_xref="MIM:125305"
/translation="MERLQKQPLTSPGSVSPSRDSSVPGSPSSIVAKMDNQVLGYKDL
AAIPKDKAILDIERPDLMIYEPHFTYSLLEHVELPRSRERSLSPKSTSPPPSPEVWAD
SRSPGIISQASAPRTTGTPRTSLPHFHHPETSRPDSNIYKKPPIYKQRESVGGSPQTK
HLIEDLIIESSKFPAAQPPDPNQPAKIETDYWPCPPSLAVVETEWRKRKASRRGAEEE
EEEEDDDSGEEMKALRERQREELSKVTSNLGKMILKEEMEKSLPIRRKTRSLPDRTPF
HTSLHQGTSKSSSLPAYGRTTLSRLQSTEFSPSGSETGSPGLQIYPYEMLVVTNKGRT
KLPPGVDRMRLERHLSAEDFSRVFAMSPEEFGKLALWKRNELKKKASLF"
misc_feature 1355..1462
/gene="EPB49"
/gene_synonym="DEMATIN"
/gene_synonym="DMT"
/note="VHP; Region: Villin headpiece domain"
/db_xref="CDD:smart00153"
BASE COUNT 569 a 830 c 701 g 479 t
ORIGIN
1 gtgaccttgt ggggaaagga gccaagaacg gggcgtcggg gggcctggga cccccctgcc
61 tgagagatac aggaatcctg gccccgtgtt gtggacacaa gcgcccatcc tcaaggtcct
121 gagaactcct gaacttccaa agcctggaga gtcaccgccg agggatgagg acgcgccagc
181 ccgggggaac gcgccagctg ctttcgcggc cccaagcgcg cagtgcccag cagccgcgcc
241 gagcctgaca cgctgtcctc tcccctcgcg cacagggctc tgcgagtgac ccggcgggcg
301 agctccgtgc tgcatggaac ggctgcagaa gcaaccactt acctcccccg ggagcgtgag
361 cccctcccga gattccagtg tgcctggctc tccctccagc atcgtggcca agatggacaa
421 tcaggtgctg ggctacaagg acctggctgc catccccaag gacaaggcca tcctggacat
481 cgagcggccc gacctcatga tctacgagcc tcactttact tattccctcc tggaacacgt
541 ggagctgcct cgcagccgcg agcgctcgct gtcacccaaa tccacatccc ccccaccatc
601 cccagaggtg tgggcggaca gccggtcgcc tggaatcatc tctcaggcct cggcccccag
661 aaccactgga accccccgga ccagcctgcc ccatttccac caccctgaga cctcccgccc
721 agattccaac atctacaaga agcctcccat ctataagcag agagagtccg tgggaggcag
781 ccctcagacc aagcacctca tcgaggatct catcatcgag tcatccaagt ttcctgcagc
841 ccagccccca gaccccaacc agccagccaa aatcgaaacc gactactggc catgcccccc
901 gtctctggct gttgtggaga cagaatggag gaagcggaag gcgtctcgga ggggagcaga
961 ggaagaggag gaggaggaag atgacgactc tggagaggag atgaaggctc tcagggagcg
1021 tcagagagag gaactcagta aggttacttc caacttggga aagatgatct tgaaagaaga
1081 gatggaaaag tcattgccga tccgaaggaa aacccgctct ctgcctgacc ggacaccctt
1141 ccatacctcc ttgcaccagg gaacgtctaa atcttcctct ctccccgcct atggcaggac
1201 caccctgagc cggctacagt ccacagagtt cagcccatca gggagtgaga ctggaagccc
1261 aggcctgcag atctatccct atgaaatgct agtggtgacc aacaaggggc gaaccaagct
1321 gccaccgggg gtggatcgga tgcggcttga gaggcatctg tctgccgagg acttctcaag
1381 ggtatttgcc atgtcccctg aagagtttgg caagctggct ctgtggaagc ggaatgagct
1441 caagaagaag gcctctctct tctgatggcc cccacctgct ccgggacggc ccccttaccc
1501 ctgctgcttc agggtttttc cccggcgggt tgggaggggc aggaggtggg gtggaaatag
1561 ggtgggctcc tttcctcagg tagagtgggg ggccaaaacc tctgcagtcc ccggcagtga
1621 gctatggact ttcttccccc tcacaaggct gggggcctcc tgctctcgtc cctggccctc
1681 cctgcacagg gcaaagccag tctgggctct ggcacacaga gttcatgttt gcgccctctc
1741 cctgcccctc accccagagg gtgaggagga atgaggggca ttggtggtta ggccggttgg
1801 ctgtcttgaa cagctggagg gaagatgcag gggtgggaag cggccaggca gaaagagctc
1861 caggctcttg tgtcgcccac ccagccctcc catactcact cctgacagct ttcctgcact
1921 gcagcttcct gctcctctga ctctagtggg aacaggcccc agctcagcct ccggcaggga
1981 ggtcacccct ccacttcagc ttgccctgac ctccgctcgc aaaccccgag cttccaagcc
2041 ttttgctcca gccctgcggc ttccccagaa gcctgggctt agggtggaga tgccgcctac
2101 acacgatcct ggccctccac ctgcctccag gccacgaaat gggaattcca gcactaagcc
2161 aggcaccggg cagaagctgg gccttccgcc tcccttggat ggggtcaaga ggccaggcct
2221 ggcacatttt ggagtgtcct ggctaccagc tctcacctac acccacgcac ccccccacac
2281 actatgctct ctcaagaatg taatttattg gggccccccc agctgctttc ctcacctgcc
2341 cctgccctac cttacacccc cagcttgact tctttccagt ccacgtgtgt atataatgat
2401 atctatattt ttgcccaggt ctgggtattg ctcctgccca gaccctgaca tccctttcca
2461 ctgtgtgtgt gaccatgctg ggggaggggg actctgcttg gaattaaaag gttgcattgg
2521 gtccctaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaa
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