LOCUS BC052586 4667 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens schlafen family member 11, mRNA (cDNA clone MGC:59997
IMAGE:6258140), complete cds.
ACCESSION BC052586
VERSION BC052586.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4667)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4667)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (16-MAY-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 47 Row: h Column: 15
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 42476006.
FEATURES Location/Qualifiers
source 1..4667
/db_xref="H-InvDB:HIT000053803"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:59997 IMAGE:6258140"
/tissue_type="Skin, melanoma, melanotic"
/clone_lib="NIH_MGC_112"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..4667
/gene="SLFN11"
/gene_synonym="FLJ34922"
/gene_synonym="SLFN8/9"
/db_xref="GeneID:91607"
/db_xref="HGNC:HGNC:26633"
CDS 154..2859
/gene="SLFN11"
/gene_synonym="FLJ34922"
/gene_synonym="SLFN8/9"
/codon_start=1
/product="schlafen family member 11"
/protein_id="AAH52586.1"
/db_xref="GeneID:91607"
/db_xref="HGNC:HGNC:26633"
/translation="MEANQCPLVVEPSYPDLVINVGEVTLGEENRKKLQKIQRDQEKE
RVMRAACALLNSGGGVIRMAKKVEHPVEMGLDLEQSLRELIQSSDLQAFFETKQQGRC
FYIFVKSWSSGPFPEDRSVKPRLCSLSSSLYRRSETSVRSMDSREAFCFLKTKRKPKI
LEEGPFHKIHKGVYQELPNSDPADPNSDPADLIFQKDYLEYGEILPFPESQLVEFKQF
STKHFQEYVKRTIPEYVPAFANTGGGYLFIGVDDKSREVLGCAKENVDPDSLRRKIEQ
AIYKLPCVHFCQPQRPITFTLKIVDVLKRGELYGYACMIRVNPFCCAVFSEAPNSWIV
EDKYVCSLTTEKWVGMMTDTDPDLLQLSEDFECQLSLSSGPPLSRPVYSKKGLEHKKE
LQQLLFSVPPGYLRYTPESLWRDLISEHRGLEELINKQMQPFFRGILIFSRSWAVDLN
LQEKPGVICDALLIAQNSTPILYTILREQDAEGQDYCTRTAFTLKQKLVNMGGYTGKV
CVRAKVLCLSPESSAEALEAAVSPMDYPASYSLAGTQHMEALLQSLVIVLLGFRSLLS
DQLGCEVLNLLTAQQYEIFSRSLRKNRELFVHGLPGSGKTIMAMKIMEKIRNVFHCEA
HRILYVCENQPLRNFISDRNICRAETRKTFLRENFEHIQHIVIDEAQNFRTEDGDWYG
KAKSITRRAKGGPGILWIFLDYFQTSHLDCSGLPPLSDQYPREELTRIVRNADPIAKY
LQKEMQVIRSNPSFNIPTGCLEVFPEAEWSQGVQGTLRIKKYLTVEQIMTCVADTCRR
FFDRGYSPKDVAVLVSTAKEVEHYKYELLKAMRKKRVVQLSDACDMLGDHIVLDSVRR
FSGLERSIVFGIHPRTADPAILPNVLICLASRAKQHLYIFPWGGH"
BASE COUNT 1294 a 1012 c 1073 g 1288 t
ORIGIN
1 gcttcggaag cgctggagct tgagaggtca gagagggtcc ttgcccccgg cctgggactc
61 cggagttgcg tttctacccg tgcttcaggg tctagcccag ccgaatccgc gtcgggctgt
121 aactcgagtg ccagtttcag ctgtgagttc aacatggagg caaatcagtg ccccctggtt
181 gtggaaccat cttacccaga cctggtcatc aatgtaggag aagtgactct tggagaagaa
241 aacagaaaaa agctgcagaa aattcagaga gaccaagaga aggagagagt tatgcgggct
301 gcatgtgctt tattaaactc aggaggagga gtgattcgaa tggccaagaa ggttgagcat
361 cccgtggaga tgggactgga tttagaacag tctttgagag agcttattca gtcttcagat
421 ctgcaggctt tctttgagac caagcaacaa ggaaggtgtt tttacatttt tgttaaatct
481 tggagcagtg gccctttccc tgaagatcgc tctgtcaagc cccgcctttg cagcctcagt
541 tcttcattat accgtagatc tgagacctct gtgcgttcca tggactcaag agaggcattc
601 tgtttcctga agaccaaaag gaagccaaaa atcttggaag aaggaccttt tcacaaaatt
661 cacaagggtg tataccaaga gctccctaac tcggatcctg ctgacccaaa ctcggatcct
721 gctgacctaa ttttccaaaa agactatctt gaatatggtg aaatcctgcc ttttcctgag
781 tctcagttag tagagtttaa acagttctct acaaaacact tccaagaata tgtaaaaagg
841 acaattccag aatacgtccc tgcatttgca aacactggag gaggctatct ttttattgga
901 gtggatgata agagtaggga agtcctggga tgtgcaaaag aaaatgttga ccctgactct
961 ttgagaagga aaatagaaca agccatatac aaactacctt gtgttcattt ttgccaaccc
1021 caacgcccga taaccttcac actcaaaatt gtggatgtgt taaaaagggg agagctctat
1081 ggctatgctt gcatgatcag agtaaatccc ttctgctgtg cagtgttctc agaagctccc
1141 aattcatgga tagtggagga caagtacgtc tgcagcctga caaccgagaa atgggtaggc
1201 atgatgacag acacagatcc agatcttcta cagttgtctg aagattttga atgtcagctg
1261 agtctatcta gtgggcctcc ccttagcaga ccagtgtact ccaagaaagg cctggaacat
1321 aaaaaggaac tccagcaact tttattttca gtcccaccag gatatttgcg atatactcca
1381 gagtcactct ggagggacct gatctcagag cacagaggac tagaggagtt aataaataag
1441 caaatgcaac ctttctttcg gggaattttg atcttctcta gaagttgggc tgtggacctg
1501 aacttgcagg agaagccagg agtcatctgt gatgctctgc tgatagcaca gaacagcacc
1561 cccattctct acaccattct cagggagcag gatgcagagg gccaggacta ctgcactcgc
1621 actgccttta ctttgaagca gaagctagtg aacatggggg gctacaccgg gaaggtgtgt
1681 gtcagggcca aggtcctctg cctgagtcct gagagcagcg cagaggcctt ggaggctgca
1741 gtgtctccga tggattaccc tgcgtcctat agccttgcag gcacccagca catggaagcc
1801 ctgctgcagt ccctcgtgat tgtcttactc ggcttcaggt ctctcttgag tgaccagctc
1861 ggctgtgagg ttttaaatct gctcacagcc cagcagtatg agatattctc cagaagcctc
1921 cgcaagaaca gagagttgtt tgtccacggc ttacctggct cagggaagac catcatggcc
1981 atgaagatca tggagaagat caggaatgtg tttcactgtg aggcacacag aattctctac
2041 gtttgtgaaa accagcctct gaggaacttt atcagtgata gaaatatctg ccgagcagag
2101 acccggaaaa ctttcctaag agaaaacttt gaacacattc aacacatcgt cattgacgaa
2161 gctcagaatt tccgtactga agatggggac tggtatggga aggcaaaaag catcactcgg
2221 agagcaaagg gtggcccagg aattctctgg atctttctgg attactttca gaccagccac
2281 ttggattgca gtggcctccc tcctctctca gaccaatatc caagagaaga gctcaccaga
2341 atagttcgca atgcagatcc aatagccaag tacttacaaa aagaaatgca agtaattaga
2401 agtaatcctt catttaacat ccccactggg tgcctcgagg tatttcctga agccgaatgg
2461 tcccagggtg ttcagggaac cttacgaatt aagaaatact tgactgtgga gcaaataatg
2521 acctgtgtgg cagacacgtg caggcgcttc tttgataggg gctattctcc aaaggatgtt
2581 gctgtgcttg tcagcaccgc aaaagaagtg gagcactata agtatgagct cttgaaagca
2641 atgaggaaga aaagggtggt gcagctcagt gatgcatgtg atatgttggg tgatcacatt
2701 gtgttggaca gtgttcggcg attctcaggc ctggaaagga gcatagtgtt tgggatccat
2761 ccaaggacag ctgacccagc tatcttaccc aatgttctga tctgtctggc ttccagggca
2821 aaacaacacc tgtatatttt tccgtggggt ggccattagg aagaactcca aatcaaaatg
2881 ctatgtaaat gtctatgggt gacagtctgc tgatggtaga aacctttctt tttagttcac
2941 aagtcagaga tttggacgga gctgacacaa agagtttgga gctcccccat ttctggctct
3001 cctttcaggg gttccttccc caaccctttt cagcagcggt ggctgccccc cattctgacc
3061 cctgactctt ccagccagaa agatggtggt tttctaaagg aactttagct gtcctgcaca
3121 atgccgatct gtgtcttgca ttttgggtaa aagccataaa aataagaaac tcagcctgtg
3181 gcctttcttt cttccaaggc tgggcttctt tttttaagtg acttcatgca gtttgttgct
3241 tttaaaaatt tgtccagaat cgttttctgc agaagcatgg tctgttagga gcttactggc
3301 cgtagcagaa gcaattgttt cctgaattct tgacatttat ctttgctgta ttcatttagg
3361 gcttgggaga gtccgaagat aattcagtca ctgtcagatt aataattttg tcaggacaaa
3421 gaataccgtt atgattattt aatcctttaa aattgtggtc tccagagctt gttctcagaa
3481 tggcccagac caagccttaa ttgtgatagt gaatattaat ggtcacttta aggagaaatt
3541 ataggccaag atgaaatgaa cataaacctg tttgccctgg ctttcagtgg aagatgatat
3601 tagagaccaa aatctggttc tgaaggtgtg tatcagccct aaggtgaacc agacttggga
3661 aagattgtct ttaaaaatca atgagtttat gttttaactt ctcagcttag ttctatgcat
3721 tgctctataa cacacctagt taagttttat gttattcttg aactgtgatt ttttttctat
3781 ttactttcat ggtttggtgg gccattgtta tggactgaat gtttgtgtcc cacccttcac
3841 ccccaaattc ccgtgttgaa gccccaacct gcactgtgga gctggggctg ctaaggaagt
3901 aattaaggtt acatgaagtc atggtggggc tctgatctgc taaggttggt gtccttatag
3961 ggagagaccc cagagagctt gttccctccc tccctgtgca tgcaaacaag agggcatggg
4021 agcacacaga gagatggcag ccacctacaa gccaagagga gaagcctcac aatcaaactc
4081 tcgctgctgg cgagagtctt ggactctgtc ttggacttcc agcctccaga ctgtgagaaa
4141 caaatttctg ttgtttcagc ttctcagtct ctggtgtttt gttattgcag cctgagaaca
4201 cagctgtacg attatttgtc aaacagaaaa cactgatact taacaatgct aatgcaatta
4261 tttatttgct tttcagtctc tacaaaacgt tctaaaacac taatctaaat attaacagta
4321 aaatatttgc ataactaatg gaaactaaga aatcacatga ccaatatttc acttattggt
4381 aatcttactc tactgatttc cccccagact gtgatttttg aacttccttg cctttctcct
4441 gtctttctgt gtttattcat ggaattccag ttatctgggc ttgaaattgc aggctctcct
4501 aacttaagca aaatctgaca gatcagcaaa atgagataaa tgtttctttt ttctttctga
4561 ctgcattaaa tcagatacaa ctcagcatta aaaagctatc tttgtaaatg ttgttactaa
4621 taaattagtc ttataagatc cctggaaaaa aaaaaaaaaa aaaaaaa
//