LOCUS BC052572 4230 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens serum response factor (c-fos serum response
element-binding transcription factor), mRNA (cDNA clone MGC:59837
IMAGE:6462845), complete cds.
ACCESSION BC052572
VERSION BC052572.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4230)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4230)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (16-MAY-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 47 Row: m Column: 10
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 61743976.
FEATURES Location/Qualifiers
source 1..4230
/db_xref="H-InvDB:HIT000053795"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:59837 IMAGE:6462845"
/tissue_type="Lung, epidermoid carcinoma"
/clone_lib="NIH_MGC_101"
/lab_host="DH10B"
/note="Vector: pOTB7"
gene 1..4230
/gene="SRF"
/db_xref="GeneID:6722"
/db_xref="HGNC:HGNC:11291"
/db_xref="MIM:600589"
CDS 363..1889
/gene="SRF"
/codon_start=1
/product="serum response factor (c-fos serum response
element-binding transcription factor)"
/protein_id="AAH52572.1"
/db_xref="GeneID:6722"
/db_xref="HGNC:HGNC:11291"
/db_xref="MIM:600589"
/translation="MLPTQAGAAAALGRGSALGGSLNRTPTGRPGGGGGTRGANGGRV
PGNGAGLGPGRLEREAAAAAATTPAPTAGALYSGSEGDSESGEEEELGAERRGLKRSL
SEMEIGMVVGGPEASAAATGGYGPVSGAVSGAKPGKKTRGRVKIKMEFIDNKLRRYTT
FSKRKTGIMKKAYELSTLTGTQVLLLVASETGHVYTFATRKLQPMITSETGKALIQTC
LNSPDSPPRSDPTTDQRMSATGFEETDLTYQVSESDSSGETKDTLKPAFTVTNLPGTT
STIQTAPSTSTTMQVSSGPSFPITNYLAPVSASVSPSAVSSANGTVLKSTGSGPVSSG
GLMQLPTSFTLMPGGAVAQQVPVQAIQVHQAPQQASPSRDSSTDLTQTSSSGTVTLPA
TIMTSSVPTTVGGHMMYPSPHAVMYAPTSGLGDGSLTVLNAFSQAPSTMQVSHSQVQE
PGGVPQVFLTASSGTVQIPVSAVQLHQMAVIGQQAGSSSNLTELQVVNLDTAHSTKSE
"
BASE COUNT 821 a 1263 c 1299 g 847 t
ORIGIN
1 gaagggtcgg gggatccctc cgccgccagc gcgtggtccc ggccccctcc acccgccgtc
61 tcggccgcgg ccagcagccc ctgccccccg ggggacgctg acggccgccc ggcgcgccgc
121 cctagcagac ggacaggggg cgctgcgcgc ggcctggggc aacccgggcc acaggggcag
181 gaaagtgagg gcccaggtcg gcccgggcgt gcaggggccc cgggttcgca gcggcggccg
241 cggcagcgat agcggcacta gcagcagcgg gagtgccggg ttgagccggg aagccgatgg
301 cggcggctgc ggcggctccg attcctcgct gactgcccgt ccgccctcct gcatcgagcg
361 ccatgttacc gacccaagct ggggccgcgg cggctctggg ccggggctcg gccctggggg
421 gcagcctgaa ccggaccccg acggggcggc cgggcggcgg cggcgggaca cgcggggcta
481 acgggggccg ggtccccggg aatggcgcgg ggctcgggcc cggccgcctg gagcgggagg
541 ctgcggcagc ggcggcaacc accccggcgc ccaccgcggg ggccctctac agcggcagcg
601 agggcgactc ggagtcgggc gaggaggagg agctgggcgc cgagcggcgc ggcctgaagc
661 ggagcctgag cgagatggag atcggtatgg tggtcggtgg gcccgaggcg tcggcagcgg
721 ccaccggggg ctacgggccg gtgagcggcg cggtgagcgg ggccaagccg ggtaagaaga
781 cccggggccg cgtgaagatc aagatggagt tcatcgacaa caagctgcgg cgctacacga
841 ccttcagcaa gaggaagacg ggcatcatga agaaggccta tgagctgtcc acgctgacag
901 ggacacaggt gctgttgctg gtggccagtg agacaggcca tgtgtatacc tttgccaccc
961 gaaaactgca gcccatgatc accagtgaga ccggcaaggc actgattcag acctgcctca
1021 actcgccaga ctctccaccc cgttcagacc ccacaacaga ccagagaatg agtgccactg
1081 gctttgaaga gacagatctc acctaccagg tgtcggagtc tgacagcagt ggggagacca
1141 aggacacact gaagccggcg ttcacagtca ccaacctgcc gggtacaacc tccaccatcc
1201 aaacagcacc tagcacctct accaccatgc aagtcagcag cggcccctcc tttcccatca
1261 ccaactacct ggcaccagtg tctgctagtg tcagccccag tgctgtcagc agtgccaatg
1321 ggactgtgct gaagagtaca ggcagcggcc ctgtctcctc tgggggcctt atgcagctgc
1381 ctaccagctt caccctcatg cctggtgggg cagtggccca gcaggtccca gtgcaggcca
1441 ttcaagtgca ccaggcccca cagcaagcgt ctccctcccg tgacagcagc acagacctca
1501 cgcagacctc ctccagcggg acagtgacgc tgcccgccac catcatgacg tcatccgtgc
1561 ccacaactgt gggtggccac atgatgtacc ctagcccgca tgcggtgatg tatgccccca
1621 cctcgggcct gggtgatggc agcctcaccg tgctgaatgc cttctcccag gcaccatcca
1681 ccatgcaggt gtcacacagc caggtccagg agccaggtgg cgtcccccag gtgttcctga
1741 cagcatcatc tgggacagtg cagatccctg tttcagcagt tcagctccac cagatggctg
1801 tgatagggca gcaggccggg agcagcagca acctcaccga gctacaggtg gtgaacctgg
1861 acaccgccca cagcaccaag agtgaatgat ccgcccgccg ccctggacag atggcccaag
1921 ggatggcacc acttatttat tgttgccttt tcacgttttc tttacacaca cgttgacggg
1981 ccgcaggagg gaggcgggga ggaggaacgg gcagccacag gactgagccc tctcactcca
2041 gccaaagaaa tgggcctgcc tgcctccacc cgtcctccct cagcctcccc ttcttcccgc
2101 cccacctccc atttctgttg ctggaggggc tgtcctcctt cctgggaccc cctcgccagc
2161 ttggctcgat gtttgccatg agtattagct tacccaatgg gaccgtgccc cacctcccca
2221 cacacaggcc ttctgtgggg ctgggcaccg tgtcctcctc tgaggaagca gttggggccc
2281 tcttgccagc ctccttgctg accccaggtc agccctgtgt ctgtcacagg ctgggtcaaa
2341 agagccctgg ctctgcccct cagggggcca gctggggaga tgggggcttc ttcctcacac
2401 tgctgtcctc tcccccttca gctcctgagt agctgggcct gtgcactggg caggttcctg
2461 gggccgcctg ccctgccttg ccgctcccct tggacctcca ggggctcctg ggttggaggg
2521 aaccaccagc gttcccttct cccccttgtc ttcccccctc tcctcccagc tgctttactt
2581 aaagttgatt ttgaactttt tatttgagga gacgaagtga aaacaaatct ataaatatat
2641 atttttaaaa tatttaactt ttttttatgg cgtttttctc gtccccctcc ctgcccaaac
2701 tccccttccc tggggagccc tcaggctccc cagaactggc tgggcccctg gggacagagc
2761 caccccatga gctcggggtc caccagtgtg tgggggagat tctgggtttg cccagtcctg
2821 ggttgtttcc aggagaaagc cgggggaggg gccctcaggc cattccccaa cggggtgggg
2881 agggtgaccc acagctctgg gcctcttttt gccctttagg gctgttgcta gggagaggga
2941 agagggagac caaatgtcgg ggttggggtg ggagggcgtc aggcagaggc aactgacttc
3001 atttgtgcca cacgcatggg cattgcagcc ttgcgctgtc ccaggcatgc agctgcctgg
3061 ggcccaagtt gcagtgagca gggtggggtc tgggaggggg tgagaggcag gaatgggggt
3121 cagaagaagt gggagcagct tcttgggctg agtgcagcca aaggggagcc agaaatgggc
3181 agttctccca gggagtgagc agctactgta acttttttaa attaagacaa aaagccttga
3241 agaaaatgac tttatttttc taagtgtaac ctcagtattt atgtaatttg tacaggggcc
3301 atgccccacc cccctcctcc ccctttgggg tagaccttga gggtgggcca gcataggggg
3361 gagggtcttt taccctgtgt cagagcctac cttcaccacc tatatccaga aggggagctt
3421 tttcagaaac agggcagcag tggggtgaaa ttttcttaac ccctaagact gccttcagta
3481 ggaacaagct ggcttctgtg attaggtgaa gggatggggg aagattttat gcacagccta
3541 gttatcaagg ggatgatttg ccgacatgtt tgagaacccc ctaacctcta accctcattg
3601 ctgtcttgcc ccagtttggg gtgccaagat ggaagtcacc tttctgggct ttctcctgga
3661 gatagctggg gcttatgggt ggctttcaag gctggggcat ggcaaatcag gggccagaga
3721 gcaggggagc ttgggactca ggtctgtaac tgcccagccc cttttctctg ctcttgtttc
3781 actccaccat cactcactca ctccccactc ccccacccat ggggaggaga cctttgatga
3841 attcttcctc tccttcccac aaaagacaga cccagtgagt gaatcaggca aagtgcttat
3901 aatgtgtgtt gtgtgagcgt ggccttggga ggacatgcgt gtgtcaggga tgagttgagg
3961 tgatattttt atgtgcagcg acccttggtg tttcccttcc tcggtggctc tggggtatgt
4021 gtgtgtgggt gtgtgcgcct gagtgagtgt gtgtgcttga atgtgagtgt gtatgtcagt
4081 ggtttctact tcccctggga tgctgaccca ggaatagtgg acatggtcac agtcctatgt
4141 acagagcttt cttttgtatt aaaaaaaaat actctttcaa taaatgtatc atttttgtgc
4201 acagaaaaaa aaaaaaaaaa aaaaaaaaaa
//