LOCUS BC052565 4841 bp mRNA linear HUM 18-AUG-2006
DEFINITION Homo sapiens Smg-7 homolog, nonsense mediated mRNA decay factor (C.
elegans), mRNA (cDNA clone IMAGE:6337867), partial cds.
ACCESSION BC052565
VERSION BC052565.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4841)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4841)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (16-MAY-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 47 Row: k Column: 13.
FEATURES Location/Qualifiers
source 1..4841
/db_xref="H-InvDB:HIT000099524"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:6337867"
/tissue_type="Eye, normal, pigmented retinal epithelium"
/clone_lib="NIH_MGC_43"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene <1..4841
/gene="SMG7"
/gene_synonym="EST1C"
/gene_synonym="KIAA0250"
/gene_synonym="SGA56M"
/gene_synonym="SMG-7"
/db_xref="GeneID:9887"
/db_xref="HGNC:HGNC:16792"
CDS <1..2521
/gene="SMG7"
/gene_synonym="EST1C"
/gene_synonym="KIAA0250"
/gene_synonym="SGA56M"
/gene_synonym="SMG-7"
/codon_start=2
/product="SMG7 protein"
/protein_id="AAH52565.1"
/db_xref="GeneID:9887"
/db_xref="HGNC:HGNC:16792"
/translation="FIKFHGHVYLSKSLEKLSPLREKLEEQFKRLLFQKAFNSQQLVH
VTVINLFQLHHLRDFSNETEQHTYSQDEQLCWTQLLALFMSFLGILCKCPLQNESQEE
SYNAYPLPAVKVSMDWLRLRPRVFQEAVVDERQYIWPWLISLLNSFHPHEEDLSSISA
TPLPEEFELQGFLALRPSFRNLDFSKGHQGITGDKEGQQRRIRQQRLISIGKWIADNQ
PRLIQCENEVGKLLFITEIPELILEDPSEAKENLILQETSVIESLAADGSPGLKSVLS
TSRNLSNNCDTGEKPVVTFKENIKTREVNRDQGRSFPPKEVKSQTELRKTPVSEARKT
PVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAGVS
VPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLP
AQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQV
QGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPSEV
KVPEFYWDSSYSMADNRSVMAQQANIDRRGKRSPGVFRPEQDPVPRMPFEKSLLEKPS
ELMSHSSSFLSLTGFSLNQERYPNNSMFNEVYGKNLTSSSKAELSPSMAPQETSLYSL
FEGTPWSPSLPASSDHSTPASQSPHSSNPSSLPSSPPTHNHNSVPFSNFGPIGTPDNR
DRRTADRWKTDKPAMGGFGIDYLSATSSSESSWHQASTPSGTWTGHGPSMEDSSAVLM
ESLKSIWSSSMMHPGPSALEQLLMQQKQKQQRGQGTMNPPH"
BASE COUNT 1317 a 1218 c 1071 g 1235 t
ORIGIN
1 ctttattaaa ttccacggtc atgtgtacct gagtaagagc ttggaaaagt tgagccctct
61 tcgagagaaa ttggaagaac agtttaagag gctgctattc caaaaagctt tcaactctca
121 gcagttagtt catgtcactg tcattaacct gtttcaactt catcaccttc gtgactttag
181 caatgaaacc gagcagcaca cttatagcca agatgagcag ctatgttgga cacagttgct
241 ggccctcttt atgtcttttc ttggcatcct gtgcaagtgt cctctacaga atgagtctca
301 ggaggagtcc tacaatgcct atcctcttcc agcagtcaag gtctccatgg actggctaag
361 actcagaccc agggtctttc aggaggcagt ggtggatgaa agacagtaca tttggccctg
421 gttgatttct cttctgaata gtttccatcc ccatgaagag gacctctcaa gtattagtgc
481 gacaccactt ccagaggagt ttgaattaca aggatttttg gcattgagac cttctttcag
541 gaacttggat ttttccaaag gtcaccaggg tattacaggg gacaaagaag gccagcaacg
601 acgaatacga cagcaacgct tgatctctat aggcaaatgg attgctgata atcagccaag
661 gctgattcag tgtgaaaatg aggtagggaa attgttgttt atcacagaaa tcccagaatt
721 aatactggaa gaccccagtg aagccaaaga gaacctcatt ctgcaagaaa catctgtgat
781 agagtcgctg gctgcagatg ggagcccagg gctaaaatca gtgctatcta caagccgaaa
841 tttaagcaac aactgtgaca caggagagaa gccagtggtt accttcaaag aaaacattaa
901 gacacgagaa gtgaacagag accaaggaag aagttttcct cccaaagagg taaaatccca
961 gacagaacta agaaagactc cagtgtctga agccagaaaa acacctgtaa ctcaaacccc
1021 aactcaagca agtaactccc agttcatccc cattcatcac cctggagcct tccctcctct
1081 tcccagcagg ccagggtttc cgcccccaac atatgttatc cccccgcctg tggcattttc
1141 tatgggctca ggttacacct tcccagctgg tgtttctgtc ccaggaacct ttcttcagcc
1201 tacagctcac tctccagcag gaaaccaggt gcaagctggg aaacagtccc acattcctta
1261 cagccagcaa cggccctctg gaccagggcc aatgaaccag ggacctcaac aatcacagcc
1321 accttcccag caacccctta catctttacc agctcagcca acagcacagt ctacaagcca
1381 gctgcaggtt caagctctaa ctcagcaaca acaatcccct acaaaagctg tgccggcttt
1441 ggggaaaagc ccgcctcacc actctggatt ccagcagtat caacaggcag atgcctccaa
1501 acagctgtgg aatccccctc aggttcaagg cccattaggg aaaattatgc ctgtgaaaca
1561 gccctactac cttcagaccc aagaccccat aaaactgttt gagccgtcat tgcaacctcc
1621 tgtaatgcag cagcagcctc tagaaaaaaa aatgaagcct tttcccatgg agccatataa
1681 ccataatccc tcagaagtca aggtcccaga attctactgg gattcttcct acagcatggc
1741 tgataacaga tctgtaatgg cacagcaagc aaacatagac cgcaggggca aacggtcacc
1801 aggagtcttc cgtccagagc aggatcctgt acccagaatg ccgtttgaga aatccttatt
1861 ggagaagccc tcagagctca tgtcacattc atcctctttc ctgtccctca ccggattctc
1921 tctcaatcag gaaagatacc caaataatag tatgttcaat gaggtatatg ggaaaaacct
1981 gacatccagc tccaaagcag aactcagtcc ctcaatggcc ccccaggaaa catctctgta
2041 ttcccttttt gaagggactc cgtggtctcc atcacttcct gccagttcag atcattcaac
2101 accagccagc cagtctcctc attcctctaa cccaagcagc ctacccagct ctcctccaac
2161 acacaaccat aattctgttc cattctccaa ttttggaccc attgggactc cagataacag
2221 ggatagaagg actgcagatc ggtggaaaac tgataagcca gccatgggtg ggtttggcat
2281 tgattatctc tcagcaacgt catcctctga gagcagttgg catcaggcca gcactccgag
2341 tggcacctgg acaggccatg gcccttccat ggaggattcc tctgctgtcc tcatggaaag
2401 cctaaagtct atctggtcca gttccatgat gcatcctgga ccttctgctc tggagcagct
2461 gttaatgcag cagaagcaga aacagcaacg gggacaaggc accatgaacc ctccacactg
2521 aggccaaagt ggcaacctgg gaatgaaggc tccataaacc atggcatgtt gggtttgcag
2581 gactggccca cacagtcccc tgcaggtggc agccctcttt tctgtttctc gctgtcaaga
2641 gggtgtaagt attccaccag cccgctgagt gtgcacgaaa tgttcgcagt gcaacaaaaa
2701 gaaaaatcca tcaggaactc tccgtccccc cggggccttc cggagggaga gagagaggaa
2761 ctgctgttta tctcactcag ttacttggta tcaccgcctc ttaccttctc catcgtgcat
2821 gtccccagcc acatgggaag tgaaagctga gaagggaagg cagatgggag aagccaatgg
2881 gaacttctca gtcctttttt cctctttggg gaataaaata ggaatccatt aatgattgct
2941 ttgctgactg agaaggtagt tgaaattatt cttaaacatc ttttattatt attactctca
3001 gtagtaaaat atcacactga attcttccat acacaggtgt gcttctagtc agtgtgtagc
3061 aaggaaagcc ccgttcactg ctcctgtgag aggttggtgg tgacaggatg gggaaccgac
3121 ctcttcagcc agtggaaatg ttccataagg gagagttcaa ggcctgtcag aaggctctgg
3181 taggccttcc tctggccagg agactccagc agggaatgcc cttcactctg taggtgctcg
3241 agccccaatc gaggatacag tgtgggtggt ggtgctgggc tggactagca ggtagactgc
3301 tgtaggattt caaattacgt ttttgattcc tgtacatttt acagtcgcac agcaagcagt
3361 ctcacagaag gcaggctagt ccattcacag cctgacacgt tctaataggt agaagctttc
3421 agtgtggtta ttttttcttt ggttggtttt tgtgccccca ttctacttcc caccctcctg
3481 ccccatctcc atcccttctt ttacccaatg ctgtatgcta gtaattgttt ttattcctaa
3541 tgtgtgcaac atcacatctc cccaagaagc aacagcatgg ggtccagcag ttggggccca
3601 aaagacagtc tgaagaggaa ggaagcagca gtatctgcgt agcccacaga gggcccaggc
3661 ccctgcccag ctgcagtctc ccagcctcca ctttcagagt gaaattcaag gcagcacgga
3721 catgtgccca tcaggcacag aagaaaacac gacgtcgtcc attttggaag agacgaaaga
3781 aaggaaaata aactctttgt atgatattta ttaggaggaa agaggactga aaatgttctt
3841 gtgtagaaac agaaggacag catttctgtt agtcatttcc tggaaaagta atattttaag
3901 gggaaattat ggaaacaatc taattgttca attgctgtgc tagtggtagg gtttattttc
3961 tgggaggtct ctcctttgtg tgtctgtatg tttgtgtaca cacacgtgcc catctgctgt
4021 cccagagggg aggggttgtg tgtgcgagtg tatggagtta gtgtggaact taagagctgg
4081 aagacagctg tagagcaaag cacatccagg agccccagtt gtcactgcag tctgggcaac
4141 cccagcaatg aaaaggggtg agataacgct cattgctttt cagagagagt ggttggagcc
4201 cccccccccc cccgtatgct tacattattg ctcttttagt ttgacatggt gtttgggttt
4261 tgtttttttg aaaggtctga aaaggtgaag ccccctaccc aatggcaata tgaaaccttt
4321 tgtgcttctc ttcagcccct tccctgtgtc cacctttctc tcctcttccc aagccttttt
4381 cctactacct ttacccagtt tgtgtgtttg agctctgcat tcaggcagct gcaacattcc
4441 agtgtttgaa ctgtcactga ttcttgcgcc ctagacaagc taaccaggtt taccatctca
4501 ctcccagtaa tacccagctc ctatctaaag ccccattctg catgagaatt tggtgtttgg
4561 aatgttttct gactcttggg gcgggattcc tcgccttatc atcctcactg tggagtaatg
4621 agggggagga gaatctttat cagaaactgg ttttgtgtag taaactttct tttgtggttt
4681 tttgttttgt tttctgggtt ttgttttttg tttttgtctg tgcaagacct gcagctgctg
4741 aaaatcagct ttgcctttaa ttaaaccatg ttctctccaa ccaaaaaaaa aaaaaaaaaa
4801 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa a
//