LOCUS BC052250 3525 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens solute carrier family 7 (cationic amino acid
transporter, y+ system), member 8, mRNA (cDNA clone MGC:59794
IMAGE:6260264), complete cds.
ACCESSION BC052250
VERSION BC052250.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3525)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3525)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (02-MAY-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 47 Row: h Column: 11
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 33286427.
FEATURES Location/Qualifiers
source 1..3525
/db_xref="H-InvDB:HIT000053754"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:59794 IMAGE:6260264"
/tissue_type="Skin, melanoma, melanotic"
/clone_lib="NIH_MGC_112"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..3525
/gene="SLC7A8"
/gene_synonym="LAT2"
/gene_synonym="LPI-PC1"
/db_xref="GeneID:23428"
/db_xref="HGNC:HGNC:11066"
/db_xref="MIM:604235"
CDS 30..1637
/gene="SLC7A8"
/gene_synonym="LAT2"
/gene_synonym="LPI-PC1"
/codon_start=1
/product="solute carrier family 7 (cationic amino acid
transporter, y+ system), member 8"
/protein_id="AAH52250.1"
/db_xref="GeneID:23428"
/db_xref="HGNC:HGNC:11066"
/db_xref="MIM:604235"
/translation="MEEGARHRNNTEKKHPGGGESDASPEAGSGGGGVALKKEIGLVS
ACGIIVGNIIGSGIFVSPKGVLENAGSVGLALIVWIVTGFITVVGALCYAELGVTIPK
SGGDYSYVKDIFGGLAGFLRLWIAVLVIYPTNQAVIALTFSNYVLQPLFPTCFPPESG
LRLLAAICLLLLTWVNCSSVRWATRVQDIFTAGKLLALALIIIMGIVQICKGEYFWLE
PKNAFENFQEPDIGLVALAFLQGSFAYGGWNFLNYVTEELVDPYKNLPRAIFISIPLV
TFVYVFANVAYVTAMSPQELLASNAVAVTFGEKLLGVMAWIMPISVALSTFGGVNGSL
FTSSRLFFAGAREGHLPSVLAMIHVKRCTPIPALLFTCISTLLMLVTSDMYTLINYVG
FINYLFYGVTVAGQIVLRWKKPDIPRPIKINLLFPIIYLLFWAFLLVFSLWSEPVVCG
IGLAIMLTGVPVYFLGVYWQHKPKCFSDFIELLTLVSQKMCVVVYPEVERGSGTEEAN
EDMEEQQQPMYQPTPTKDKDVAGQPQP"
BASE COUNT 738 a 1056 c 868 g 863 t
ORIGIN
1 cttttgaggt tgcaatccta ctgagaagga tggaagaagg agccaggcac cgaaacaaca
61 ccgaaaagaa acacccaggt gggggcgagt cggacgccag ccccgaggct ggttccggag
121 ggggcggagt agccctgaag aaagagatcg gattggtcag tgcctgtggt atcatcgtag
181 ggaacatcat cggctctgga atctttgtct cgccaaaggg agtgctggag aatgctggtt
241 ctgtgggcct tgctctcatc gtctggattg tgacgggctt catcacagtt gtgggagccc
301 tctgctatgc tgaactcggg gtcaccatcc ccaaatctgg aggtgactac tcctatgtca
361 aggacatctt cggaggactg gctgggttcc tgaggctgtg gattgctgtg ctggtgatct
421 accccaccaa ccaggctgtc atcgccctca ccttctccaa ctacgtgctg cagccgctct
481 tccccacctg cttcccccca gagtctggcc ttcggctcct ggctgccatc tgcttattgc
541 tcctcacatg ggtcaactgt tccagtgtgc ggtgggccac ccgggttcaa gacatcttca
601 cagctgggaa gctcctggcc ttggccctga ttatcatcat ggggattgta cagatatgca
661 aaggagagta cttctggctg gagccaaaga atgcatttga gaatttccag gaacctgaca
721 tcggcctcgt cgcactggct ttccttcagg gctcctttgc ctatggaggc tggaactttc
781 tgaattacgt gactgaggag cttgttgatc cctacaagaa ccttcccaga gccatcttca
841 tctccatccc actggtcaca tttgtgtatg tctttgccaa tgtcgcttat gtcactgcaa
901 tgtcccccca ggagctgctg gcatccaacg ccgtcgctgt gacttttgga gagaagctcc
961 taggagtcat ggcctggatc atgcccattt ctgttgccct gtccacattt ggaggagtta
1021 atgggtctct cttcacctcc tctcggctgt tcttcgctgg agcccgagag ggccaccttc
1081 ccagtgtgtt ggccatgatc cacgtgaagc gctgcacccc aatcccagcc ctgctcttca
1141 catgcatctc caccctgctg atgctggtca ccagtgacat gtacacactc atcaactacg
1201 tgggcttcat caactacctc ttctatgggg tcacggttgc tggacagata gtccttcgct
1261 ggaagaagcc tgatatcccc cgccccatca agatcaacct gctgttcccc atcatctact
1321 tgctgttctg ggccttcctg ctggtcttca gcctgtggtc agagccggtg gtgtgtggca
1381 ttggcctggc catcatgctg acaggagtgc ctgtctattt cctgggtgtt tactggcaac
1441 acaagcccaa gtgtttcagt gacttcattg agctgctaac cctggtgagc cagaagatgt
1501 gtgtggtcgt gtaccccgag gtggagcggg gctcagggac agaggaggct aatgaggaca
1561 tggaggagca gcagcagccc atgtaccaac ccactcccac gaaggacaag gacgtggcgg
1621 ggcagcccca gccctgagga ccaccattcc ctggctactc tctccttcct ccccctttta
1681 tcctacctcc ctgccttggt cccgccaaca catgcgagta cacacacacc cctctctgct
1741 tttgtcaggc agtggtagga ctttggtgtg ggtggtgaga aattgtaaac aaaactgaca
1801 ttcataccca aagaaccagc ctctcacccc agggtccatg tcccaggccc cactccagtg
1861 ctgcccacac tcccagctgc tggaggagag gggagatgcc aaggtgccct gcaggacctc
1921 cctccgggcc acaccctcag ctgcctcttc aggaaccgga gctcattact gccttccctc
1981 ccagggaggc cccttcagag aggagaggcc acaggagctg cattgtgggg ggacaggctc
2041 aagcaattct gtccccatca aggggtcagc tggagagacc caagacccta tctgttcacc
2101 agggacccaa aatccaaggg gatgcttccc tctgccctct ttcctgcccc tccccatcat
2161 acctgcaccc accccagcca gggctccctg tccagaattc ggttctcctc aggacgccaa
2221 ctcccagagc taaggaccaa ggagaagaac agcctctcca cccccaagcc aggcggttga
2281 ggaacatatt gagaaaggtt cagattgcag aaacccagcc ctgcccctgc ctcctgcatc
2341 cagcccccaa catggtgcca aagcttccag aagccaaaaa gcttctgatt tttaaggtag
2401 tgggcatctc tctcctaatg acgaagctgc tcagcaactc cacctgcccg ccgcaggaag
2461 gagcagtccc ctgctatccc tgcagccact cccagcacac ccgcacacag ccagcaccac
2521 cgcccccacc gtgcacttct cctctctggg ccttggcttg ggaccaggta cgaaggatcc
2581 ccaagccctt caggcctgag atcagagcca gatcagcctt aagtcacctc ccatccaaga
2641 acttggccta aaaatactcc cctatttcta accctcagga cggatctgat attaaatgcc
2701 ttccctggga ggaagggtgc tttccccctc cctagaggtg cccattccat accctgggag
2761 actgaggaga gcattggctg aagcccagtt cctttcccat ccatccccaa ctccaataat
2821 cccccactcc tcgcaggtct cagtgtcatg ctgtcttggg gcagggtgaa agggtagtgg
2881 cagcagggcg cccactctgg agatcctcaa aaaaggccct cctctgtggc tggcagcctc
2941 tgacctttcc ctgggcttca aaggaaggct atggagtttg ctgtgggccc tgcaaccttc
3001 ccagccactc ctgctgcact aaggacttag gatcctttta tcacaaatcg ggattctctc
3061 ccccaccccg aattctgtct gcttaaactg gaatacacag gagcccttcc tggcctggat
3121 ggtgtctccc agcttccccg cccagcttgc ccaccccata gttggtgaga tgccaagttt
3181 ggtctgagtt gtgacccctt cagagtagat gcccggcagg ctggggttgg cccctggagg
3241 gtcaggggac catcttctta ttccctcttt tctcattcct ccaacttcct cccctccttc
3301 aattattttt ttgtaaagtt gatgccttac tttttggata aatatttttg aagctggtat
3361 ttctatttct tttggatttt ttttaatgta aggttgtttt gggggatgga gttagaacct
3421 taatgataat ttctttcgtt tggtgtaggt tttagagatt tgttttgtgg agaggttttt
3481 ttcttttgat gtaataaaat ttaaaatgga aaaaaaaaaa aaaaa
//