LOCUS BC052248 1918 bp mRNA linear HUM 09-MAR-2007
DEFINITION Homo sapiens formiminotransferase cyclodeaminase, mRNA (cDNA clone
MGC:59738 IMAGE:6270063), complete cds.
ACCESSION BC052248
VERSION BC052248.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1918)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1918)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (02-MAY-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: CGAP (Stanford)
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 47 Row: h Column: 1
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 46255034.
FEATURES Location/Qualifiers
source 1..1918
/db_xref="H-InvDB:HIT000099479"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:59738 IMAGE:6270063"
/tissue_type="Liver, hepatocellular carcinoma"
/clone_lib="NIH_MGC_100"
/lab_host="DH10B"
/note="Vector: pOTB7"
gene 1..1918
/gene="FTCD"
/gene_synonym="LCHC1"
/db_xref="GeneID:10841"
/db_xref="HGNC:HGNC:3974"
/db_xref="MIM:606806"
CDS 41..1666
/gene="FTCD"
/gene_synonym="LCHC1"
/codon_start=1
/product="formiminotransferase cyclodeaminase"
/protein_id="AAH52248.2"
/db_xref="GeneID:10841"
/db_xref="HGNC:HGNC:3974"
/db_xref="MIM:606806"
/translation="MSQLVECVPNFSEGKNQEVIDAISGAITQTPGCVLLDVDAGPST
NRTVYTFVGPPECVVEGALNAARVASRLIDMSRHQGEHPRMGALDVCPFIPVRGVSVD
ECVLCAQAFGQRLAEELDVPVYLYGEAARMDSRRTLPAIRAGEYEALPKKLQQADWAP
DFGPSSFVPSWGATATGARKFLIAFNINLLGTKEQAHRIALNLREQGRGKDQPGRLKK
VQGIGWYLDEKNLAQVSTNLLDFEVTALHTVYEETCREAQELSLPVVGSQLVGLVPLK
ALLDAAAFYCEKENLFILEEEQRIRLVVSRLGLDSLCPFSPKERIIEYLVPERGPERG
LGSKSLRAFVGEVGARSAAPGGGSVAAAAAAMGAALGSMVGLMTYGRRQFQSLDTTMR
RLIPPFREASAKLTTLVDADAEAFTAYLEAMRLPKNTPEEKDRRTAALQEGLRRAVSV
PLTLAETVASLWPALQELARCGNLACRSDLQVAAKALEMGVFGAYFNVLINLRDITDE
AFKDQIHHRVSSLLQEAKTQAALVLDCLETRQE"
BASE COUNT 367 a 600 c 624 g 327 t
ORIGIN
1 catctgccca gagaggagca tctggatcaa ggtgctggcc atgtcccagc tggtggaatg
61 cgtccccaac ttttcggagg ggaagaacca ggaggtgatc gacgccatct ctggagccat
121 cacacagacc ccgggctgcg tgctgctgga tgtggacgca ggcccttcca ccaaccgcac
181 cgtgtacacc ttcgtggggc cgccggagtg cgtggtggag ggggccctca acgctgcccg
241 ggtagcttcc cgacttatcg acatgagcag gcaccaagga gagcaccccc gcatgggggc
301 cctagacgtc tgccccttca tccccgtgag gggcgtcagc gtggatgagt gtgtgctctg
361 cgcccaggcc tttggccaga ggctggcaga ggagctggac gtgccagttt acctgtacgg
421 cgaggcagcc aggatggaca gtcgccggac cctgccggcc atccgggccg gggagtacga
481 ggccctccct aagaagctcc agcaggccga ctgggcgccc gactttggtc ccagctcctt
541 tgtccccagt tggggggcca cggccacggg ggcgaggaag ttcctcattg cttttaacat
601 caacctgctc ggcacaaagg agcaagccca ccgcatcgcg ctcaacctgc gggagcaggg
661 ccgcgggaag gaccagccag gacgtctgaa gaaagttcag ggcattggct ggtacctgga
721 tgagaagaac ctggctcagg tgtccaccaa tcttctggac tttgaggtca cggcactgca
781 cacggtctac gaggagacct gccgagaagc acaggagctg agcctcccag tggtgggctc
841 acagctggtg ggcctggtgc ccctgaaggc tctgctggat gcggccgcct tctactgcga
901 gaaggagaac ctcttcatcc tggaggagga gcagcggatc aggctggtgg tgagccggct
961 gggcctggac tccctgtgcc ccttcagccc taaggagcgg atcatcgagt acctggtccc
1021 tgagcgcggg cctgagcgag gcctgggcag caagtccctg cgcgccttcg tgggggaggt
1081 gggtgcccgc tctgcggccc ccgggggcgg ctcggtggcg gcggccgctg cggccatggg
1141 tgcggcgctg ggctccatgg tgggcctcat gacctacggg cggcgccaat tccagtccct
1201 ggacacgacg atgcggcgcc tgatcccgcc cttccgcgag gcttcggcca agctaaccac
1261 gctggtggat gccgacgccg aggccttcac cgcctacctg gaagcaatga ggctccccaa
1321 gaacacacct gaggaaaagg acaggcgcac ggcggcccta caggagggtc tgaggcgggc
1381 agtctctgtg ccgctgacgc tggcggagac ggtggcctcg ctgtggccgg cgctgcagga
1441 actggcccgg tgtgggaacc tggcctgccg gtcagacctc caggtggcgg ccaaagccct
1501 ggagatgggc gtgtttggcg catatttcaa cgtgctcatc aacctgaggg acatcacaga
1561 cgaggcattt aaggaccaga tccaccatcg tgtttccagc ctcctgcagg aagccaagac
1621 ccaggctgca ctggtgctgg actgcttgga gacccggcag gagtgacgaa accccaggga
1681 cagcaggacc ttcgacgctg gaaggatagc ctcgcttccc aggtgcagct cccggcaggt
1741 ctggacagtt ccacagagca cggtactggc cctgtcctca gttcccgtcc acccttcaac
1801 cagtggctcc tgggagactt ttcctccctg cctcagctcc ctgcccagcc agcctcctgt
1861 ctccagagaa gttctccatt aaaaaataat ttagcaaatc aaaaaaaaaa aaaaaaaa
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