LOCUS BC051836 3322 bp mRNA linear HUM 11-AUG-2006
DEFINITION Homo sapiens low density lipoprotein receptor-related protein 8,
apolipoprotein e receptor, mRNA (cDNA clone MGC:60136
IMAGE:6143442), complete cds.
ACCESSION BC051836
VERSION BC051836.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3322)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3322)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (01-MAY-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 110 Row: j Column: 5.
FEATURES Location/Qualifiers
source 1..3322
/db_xref="H-InvDB:HIT000099436"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:60136 IMAGE:6143442"
/tissue_type="Eye, retinoblastoma"
/clone_lib="NIH_MGC_67"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..3322
/gene="LRP8"
/gene_synonym="APOER2"
/gene_synonym="HSZ75190"
/db_xref="GeneID:7804"
/db_xref="HGNC:HGNC:6700"
/db_xref="MIM:602600"
CDS 143..2857
/gene="LRP8"
/gene_synonym="APOER2"
/gene_synonym="HSZ75190"
/codon_start=1
/product="low density lipoprotein receptor-related protein
8, apolipoprotein e receptor"
/protein_id="AAH51836.2"
/db_xref="GeneID:7804"
/db_xref="HGNC:HGNC:6700"
/db_xref="MIM:602600"
/translation="MGLPEPGPLRLLALLLLLLLLLLLRLQHLAAAAADPLLGGQGPA
KECEKDQFQCRNERCIPSVWRCDEDDDCLDHSDEDDCPKKTCADSDFTCDNGHCIHER
WKCDGEEECPDGSDESEATCTKQVCPAEKLSCGPTSHKCVPASWRCDGEKDCEGGADE
AGCATLCAPHEFQCGNRSCLAAVFVCDGDDDCGDGSDERGCADPACGPREFRCGGDGG
GACIPERWVCDRQFDCEDRSDEAAELCGRPGPGATSAPAACATASQFACRSGECVHLG
WRCDGDRDCKDKSDEADCPLGTCRGDEFQCGDGTCVLAIKHCNQEQDCPDGSDEAGCL
QGLNECLHNNGGCSHICTDLKIGFECTCPAGFQLLDQKTCGDIDECKDPDACSQICVN
YKGYFKCECYPGYEMDLLTKNCKAAAGKSPSLIFTNRHEVRRIDLVKRNYSRLIPMLK
NVVALDVEVATNRIYWCDLSYRKIYSAYMDKASDPKEQEVLIDEQLHSPEGLAVDWVH
KHIYWTDSGNKTISVATVDGGRRRTLFSRNLSEPRAIAVDPLRGFMYWSDWGDQAKIE
KSGLNGVDRQTLVSDNIEWPNGITLDLLSQRLYWVDSKLHQLSSIDFSGGNRKTLISS
TDFLSHPFGIAVFEDKVFWTDLENEAIFSANRLNGLEISILAENLNNPHDIVIFHELK
QPRAPDACELSVQPNGGCEYLCLPAPQISSHSPKYTCACPDTMWLGPDMKRCYRAPQS
TSTTTLASTMTRTVPATTRAPGTTVHRSTYQNHSTETPSLTAAVPSSVSVPRAPSISP
STLSPATSNHSQHYANEDSKMGSTVTAAVIGIIVPIVVIALLCMSGYLIWRNWKRKNT
KSMNFDNPVYRKTTEEEDEDELHIGRTAQIGHVYPARVALSLEDDGLP"
BASE COUNT 755 a 931 c 974 g 662 t
ORIGIN
1 gccggggcgg gcggcagcgg cggcggcggc ggcggcgggg gcagcggcaa ccccggcgcc
61 gcggcaagga ctcggagggc tgagacgcgg cggcggcggc gcggggagcg cggggcgcgg
121 cggccggagc cccgggcccg ccatgggcct ccccgagccg ggccctctcc ggcttctggc
181 gctgctgctg ctgctgctgc tgctgctgct gctgcggctc cagcatcttg cggcggcagc
241 ggctgatccg ctgctcggcg gccaagggcc ggccaaggag tgcgaaaagg accaattcca
301 gtgccggaac gagcgctgca tcccctctgt gtggagatgc gacgaggacg atgactgctt
361 agaccacagc gacgaggacg actgccccaa gaagacctgt gcagacagtg acttcacctg
421 tgacaacggc cactgcatcc acgaacggtg gaagtgtgac ggcgaggagg agtgtcctga
481 tggctccgat gagtccgagg ccacttgcac caagcaggtg tgtcctgcag agaagctgag
541 ctgtggaccc accagccaca agtgtgtacc tgcctcgtgg cgctgcgacg gggagaagga
601 ctgcgagggt ggagcggatg aggccggctg tgctaccttg tgcgccccgc acgagttcca
661 gtgcggcaac cgctcgtgcc tggccgccgt gttcgtgtgc gacggcgacg acgactgtgg
721 tgacggcagc gatgagcgcg gctgtgcaga cccggcctgc gggccccgcg agttccgctg
781 cggcggcgat ggcggcggcg cctgcatccc ggagcgctgg gtctgcgacc gccagtttga
841 ctgcgaggac cgctcggacg aggcagccga gctctgcggc cgtccgggcc ccggggccac
901 gtccgcgccc gccgcctgcg ccaccgcctc ccagttcgcc tgccgcagcg gcgagtgcgt
961 gcacctgggc tggcgctgcg acggcgaccg cgactgcaaa gacaaatcgg acgaggccga
1021 ctgcccactg ggcacctgcc gtggggacga gttccagtgt ggggatggga catgtgtcct
1081 tgcaatcaag cactgcaacc aggagcagga ctgtccagat gggagtgatg aagctggctg
1141 cctacagggg ctgaacgagt gtctgcacaa caatggcggc tgctcacaca tctgcactga
1201 cctcaagatt ggctttgaat gcacgtgccc agcaggcttc cagctcctgg accagaagac
1261 ctgtggcgac attgatgagt gcaaggaccc agatgcctgc agccagatct gtgtcaatta
1321 caagggctat tttaagtgtg agtgctaccc tggctacgag atggacctac tgaccaagaa
1381 ctgcaaggct gctgctggca agagcccatc cctaatcttc accaaccggc acgaggtgcg
1441 gaggatcgac ctggtgaagc ggaactattc acgcctcatc cccatgctca agaatgtcgt
1501 ggcactagat gtggaagttg ccaccaatcg catctactgg tgtgacctct cctaccgtaa
1561 gatctatagc gcctacatgg acaaggccag tgacccgaaa gagcaggagg tcctcattga
1621 cgagcagttg cactctccag agggcctggc agtggactgg gtccacaagc acatctactg
1681 gactgactcg ggcaataaga ccatctcagt ggccacagtt gatggtggcc gccgacgcac
1741 tctcttcagc cgtaacctca gtgaaccccg ggccatcgct gttgaccccc tgcgagggtt
1801 catgtattgg tctgactggg gggaccaggc caagattgag aaatctgggc tcaacggtgt
1861 ggaccggcaa acactggtgt cagacaatat tgaatggccc aacggaatca ccctggatct
1921 gctgagccag cgcttgtact gggtagactc caagctacac caactgtcca gcattgactt
1981 cagtggaggc aacagaaaga cgctgatctc ctccactgac ttcctgagcc acccttttgg
2041 gatagctgtg tttgaggaca aggtgttctg gacagacctg gagaacgagg ccattttcag
2101 tgcaaatcgg ctcaatggcc tggaaatctc catcctggct gagaacctca acaacccaca
2161 tgacattgtc atcttccatg agctgaagca gccaagagct ccagatgcct gtgagctgag
2221 tgtccagcct aatggaggct gtgaatacct gtgccttcct gctcctcaga tctccagcca
2281 ctctcccaag tacacatgtg cctgtcctga cacaatgtgg ctgggtccag acatgaagag
2341 gtgctaccga gcacctcaat ctacctcaac tacgacgtta gcttctacca tgacgaggac
2401 agtacctgcc accacaagag cccccgggac caccgtccac agatccacct accagaacca
2461 cagcacagag acaccaagcc tgacagctgc agtcccaagc tcagttagtg tccccagggc
2521 tcccagcatc agcccgtcta ccctaagccc tgcaaccagc aaccactccc agcactatgc
2581 aaatgaagac agtaagatgg gctcaacagt cactgccgct gttatcggga tcatcgtgcc
2641 catagtggtg atagccctcc tgtgcatgag tggatacctg atctggagaa actggaagcg
2701 gaagaacacc aaaagcatga attttgacaa cccagtctac aggaaaacaa cagaagaaga
2761 agacgaagat gagctccata tagggagaac tgctcagatt ggccatgtct atcctgcacg
2821 agtggcatta agccttgaag atgatggact accctgagga tgggatcacc cccttcgtgc
2881 ctcatggaat tcagtcccat gcactacact ctggatggtg tatgactgga tgaatgggtt
2941 tctatatatg ggtctgtgtg agtgtatgtg tgtgtgtgat ttttttttta aatttatgtt
3001 gcggaaaggt aaccacaaag ttatgatgaa ctgcaaacat ccaaaggatg tgagagtttt
3061 tctatgtata atgttttata cactttttaa ctggttgcac tacccatgag gaattcgtgg
3121 aatggctact gctgactaac atgatgcaca taaccaaatg ggggccaatg gcacagtacc
3181 ttactcatca tttaaaaact atatttacag aagatgtttg gttgctgggg gggctttttt
3241 aggttttggg gcatttgttt tttgtaaata agatgattat gctttgtggc tatccatcaa
3301 cataagtaaa aaaaaaaaaa aa
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