LOCUS BC051811 2251 bp mRNA linear HUM 05-NOV-2003
DEFINITION Homo sapiens Rho GTPase activating protein 12, mRNA (cDNA clone
IMAGE:6504020), partial cds.
ACCESSION BC051811
VERSION BC051811.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2251)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2251)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (01-MAY-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 110 Row: p Column: 24
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 22095378.
FEATURES Location/Qualifiers
source 1..2251
/db_xref="H-InvDB:HIT000099423"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:6504020"
/tissue_type="Uterus, leiomyosarcoma"
/clone_lib="NIH_MGC_71"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene <1..2251
/gene="ARHGAP12"
/gene_synonym="FLJ10971"
/gene_synonym="FLJ20737"
/gene_synonym="FLJ21785"
/db_xref="GeneID:94134"
CDS <1..867
/gene="ARHGAP12"
/gene_synonym="FLJ10971"
/gene_synonym="FLJ20737"
/gene_synonym="FLJ21785"
/codon_start=1
/product="ARHGAP12 protein"
/protein_id="AAH51811.1"
/db_xref="GeneID:94134"
/translation="NDTVINDWFKVLSSTINNQAVETDEGIEEEIPDSPGIEKHDKEK
EQKDPKKLRSFKVSSIDSSEQKKTKKNLKKFLTRRPTLQAVREKGYIKDQVFGSNLAN
LCQRENGTVPKFVKLCIEHVEEHGLDIDGIYRVSGNLAVIQKLRFAVNHDEKLDLNDS
KWEDIHVITGALKMFFRELPEPLFTFNHFNDFVNAIKQEPRQRVAAVKDLIRQLPKPN
QDTMQILFRHLRRVIENGEKNRMTYQSIAIVFGPTLLKPEKETGNIAVHTVYQNQIVE
LILLELSSIFGR"
misc_feature 286..825
/gene="ARHGAP12"
/gene_synonym="FLJ10971"
/gene_synonym="FLJ20737"
/gene_synonym="FLJ21785"
/note="RhoGAP; Region: GTPase-activator protein for
Rho-like GTPases"
/db_xref="CDD:cd00159"
BASE COUNT 750 a 342 c 428 g 731 t
ORIGIN
1 aatgacactg ttattaatga ttggtttaaa gttcttagta gtacaatcaa taatcaggca
61 gtagaaactg atgaaggaat tgaagaggag ataccggatt caccaggaat agaaaagcat
121 gataaagaaa aggaacaaaa ggatcccaaa aagcttcgtt cctttaaagt atctagcata
181 gattcttcag aacagaaaaa aaccaagaaa aacttaaaga agtttcttac acgacgcccc
241 actttgcaag ctgttcgtga aaaaggttat attaaagatc aggtatttgg atccaatctc
301 gctaatctgt gtcagagaga gaatggcaca gtaccaaagt ttgtgaagtt atgtattgaa
361 catgttgaag aacatggttt ggatattgat gggatataca gagtaagtgg caacctcgca
421 gtgatccaga aactaaggtt tgcagtcaat catgatgaga aattggactt gaatgacagt
481 aaatgggaag atattcatgt cattactgga gccctcaaaa tgttttttcg agaattacca
541 gaacctcttt ttacatttaa tcattttaat gattttgtta atgcaattaa gcaagaacca
601 agacagcgag tcgctgctgt taaggaccta atcagacagt tgccaaagcc aaaccaagac
661 acaatgcaga ttcttttccg acatctcaga agagttatag aaaatggaga gaaaaatcga
721 atgacctatc agagtatagc aattgttttt ggtcccactc tattaaaacc agaaaaagag
781 actggtaata tagcagttca tactgtgtac cagaatcaga ttgtagaatt aattcttctg
841 gaactgagtt ccatcttcgg acgttgattc ttactgaaga caacctgtgg aatagaagct
901 ggattccatc agatttcaaa tgtttataca caatgtattt tattttttgg accaagcagt
961 gactctttga ttttgcactt tttttttgag ggatcagaag ggaaggggag agtcgagatg
1021 tgtgttaggc cctcatattt gctgctttgt tgcaagttga tataactgcg tgtaattatg
1081 aattcatttt atcctgaatg tttgcatttc atactctgaa tttcagtaaa aatcaaaact
1141 taaaattcta accagtcata tacactggat aatttggtaa gaaaactgta ttttttttcc
1201 ctgaaattgg ataatgtact ttcttctcaa gattcatgac ttgatagaac aatactttca
1261 gttatgttgc aaaggctctt gggcatttta aacaaaatga agtatatcca ttttgaaacc
1321 tgtgtatttc tttttcgggg tttctgcatg cagtggcagt cttaagtgcc aaaattcatt
1381 ataaccccaa aataacccct tgatgaaggc ttgctgtctt ttactgtgtt acacagcatc
1441 cttactggat atcttagttg cttgtttggg cagcacacta atattactta aaacactgtg
1501 atatactgga gttttagtta gcggaagtca gttcagggca ttttagggct gtcttgctat
1561 actgaattgt agctaacaat cctaattata tctagtacca tactgagtta ttggtatgac
1621 cctgtggaaa cacacattat tttatgtaaa tataggctaa agacttaatg tcctttagct
1681 tgtgtatata attgtgttgt atagtctcag agtacattct aaccctacat ttctaatcat
1741 tgttattggt aatcttttct gtgaatatta ggtttcctcc agaaatagtc cgttatttgg
1801 gaaagttaac tgtgtgcact tttagatatt aactacattt acaggcaaat cactgtaatg
1861 agaatggtac tggaaaaata ctgaatagac ttgctaaatg gcacatgcac tacaagagga
1921 accttttggg ttatttaata tgtacagaaa acattagaaa aaatttatta cagaattcta
1981 attccagtat gaatagtgga aacccatctg taaattagat ggatgttgga tggaaaatga
2041 cattgctaaa tttgagaatt tctttttacc tactaatgta gattgctttg tataataaaa
2101 cacagggttt ggaaggtttt gttacaggga gcatggtctg ttgaagattt ttaaaatgta
2161 tttttctaga ttaacttctg tacatgaaat gtctaataaa actctaagag gtttagagat
2221 ttttccattg gaaaaaaaaa aaaaaaaaaa a
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