LOCUS BC051799 5251 bp mRNA linear HUM 05-MAY-2003
DEFINITION Homo sapiens sterol regulatory element binding transcription factor
2, mRNA (cDNA clone IMAGE:5498684), partial cds.
ACCESSION BC051799
VERSION BC051799.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5251)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 5251)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (01-MAY-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Lou Staudt
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 107 Row: f Column: 18
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 4759169.
FEATURES Location/Qualifiers
source 1..5251
/db_xref="H-InvDB:HIT000099414"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:5498684"
/tissue_type="Lymph, lymphoma"
/clone_lib="NIH_MGC_85"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene <1..5251
/gene="SREBF2"
/gene_synonym="SREBP2"
/db_xref="GeneID:6721"
/db_xref="MIM:600481"
CDS <1..3584
/gene="SREBF2"
/gene_synonym="SREBP2"
/codon_start=3
/product="SREBF2 protein"
/protein_id="AAH51799.1"
/db_xref="GeneID:6721"
/db_xref="MIM:600481"
/translation="GARAQRKHGGGWHPSVRRCRAGVVGCHGRWRRHRPRVSLSGTAG
GASALSRAMDDSGELGGLETMETLTELGDELTLGDIDEMLQFVSNQVGEFPDLFSEQL
CSSFPGSGGSGSSSGSSGSSSSSSNGRGSSSGAVDPSVQRSFTQVTLPSFSPSAASPQ
APTLQVKVSPTSVPTTPRATPILQPRPQPQPQPQTQLQQQTVMITPTFSTTPQTRIIQ
QPLIYQNAATSFQVLQPQVQSLVTSSQVQPVTIQQQVQTVQAQRVLTQTANGTLQTLA
PATVQTVAAPQVQQVPVLVQPQIIKTDSLVLTTLKTDGSPVMAAVQNPALTALTTPIQ
TAALQVPTLVGSSGTILTTMPVMMGQEKVPIKQVPGGVKQLEPPKEGERRTTHNIIEK
RYRSSINDKIIELKDLVMGTDAKMHKSGVLRKAIDYIKYLQQVNHKLRQENMVLKLAN
QKNKLLKGIDLGSLVDNEVDLKIEDFNQNVLLMSPPASDSGSQAGFSPYSIDSEPGSP
LLDDAKVKDEPDSPPVALGMVDRSRILLCVLTFLCLSFNPLTSLLQWGGAHDSDQHPH
SGSGRSVLSFESGSGGWFDWMMPTLLLWLVNGVIVLSVFVKLLVHGEPVIRPHSRSSV
TFWRHRKQADLDLARGDFAAAAGNLQTCLAVLGRALPTSRLDLACSLSWNVIRYSLQK
LRLVRWLLKKVFQCRRATPATEAGFEDEAKTSARDAALAYHRLHQLHITGKLPAGSAC
SDVHMALCAVNLAECAEEKIPPSTLVEIHLTAAMGLKTRCGGKLGFLASYFLSRAQSL
CGPEHSAVPDSLRWLCHPLGQKFFMERSWSVKSAAKESLYCAQRNPADPIAQVHQAFC
KNLLERAIESLVKPQAKKKAGDQEEESCEFSSALEYLKLLHSFVDSVGVMSPPLSRSS
VLKSALGPDIICRWWTSAITVAISWLQGDDAAVRSHFTKVERIPKALEVTESPLVKAI
FHACRAMHASLPGKADGQQSSFCHCERASGHLWSSLNVSGATSDPALNHVVQLLTCDL
LLSLRTALWQKQASASQAVGETYHASGAELAGFQRDLGSLRRLAHSFRPAYRKVFLHE
ATVRLMAGASPTRTHQLLEHSLRRRTTQSTKHGEVDAWPGQRERATAILLACRHLPLS
FLSSPGQRAVLLAEAARTLEKVGDRRSCNDCQQMIVKLGGGTAIAAS"
BASE COUNT 1077 a 1585 c 1460 g 1129 t
ORIGIN
1 gcggcgcccg ggcgcaacgc aaacatggcg gcgggtggca cccgtcggtg aggcggtgcc
61 gggcgggggt tgtcgggtgt catgggcggt ggcgacggca ccgcccccgc gtctccctga
121 gcgggacggc agggggggct tctgcgctga gccgggcgat ggacgacagc ggcgagctgg
181 gtggtctgga gaccatggag accctcacgg agctgggcga cgagctgacc ctgggagaca
241 tcgacgagat gctgcaattt gtcagtaatc aagtgggaga gttccctgac ttgttttcag
301 aacagctgtg tagctccttt cctggcagtg gtggtagtgg tagcagcagc ggcagcagtg
361 gcagcagcag cagcagcagc aatggcaggg gcagcagcag cggagctgtg gacccttcag
421 tgcaacggtc attcacccag gtcacattac cttccttctc tccctcggcg gcctccccac
481 aggctccaac tctgcaagtc aaggtttctc ccacctcagt tcccaccaca cccagggcaa
541 ctcctattct tcagccccgc ccccagcccc agcctcaacc tcaaactcag ctgcaacaac
601 agacggtaat gatcacgcca acattcagca ccactccgca gacgaggatc atccagcagc
661 ctttgatata ccagaatgca gctactagct ttcaagtcct tcagcctcaa gtccaaagcc
721 tggtgacatc ctcccaggta cagccggtca ccattcagca gcaggtgcag acagtacagg
781 cccagcgggt gctgacacaa acggccaatg gcacgctgca gacccttgcc ccggctacgg
841 tgcagacagt tgctgcgcca caggtgcagc aggtcccggt cctggtccag cctcagatca
901 tcaagacaga ttcccttgtt ttgaccacac tgaagacaga tggcagccct gttatggctg
961 cggtccagaa cccggccctc accgccctca ccacccctat ccagacggct gcccttcaag
1021 taccaaccct ggtgggcagc agtgggacca ttctgaccac aatgcctgta atgatggggc
1081 aagagaaagt gcccattaag caggtacctg ggggagtcaa gcagcttgag ccccccaaag
1141 aaggagaaag gcggacaacc cataatatca ttgagaaacg atatcgctcc tccatcaatg
1201 acaaaatcat cgaattgaaa gacctggtca tggggacaga cgccaagatg cacaagtctg
1261 gcgttctgag gaaggccatt gattacatca aatacttgca gcaggtcaat cataaactgc
1321 gccaggagaa catggtgctg aagctggcaa atcaaaagaa caagcttcta aagggcatcg
1381 acctaggcag tctggtggac aatgaggtgg acctgaagat cgaggacttt aatcagaatg
1441 tccttctgat gtccccccca gcctctgact cagggtccca ggctggcttc tctccctact
1501 ccattgactc tgagccagga agccctctat tggatgatgc aaaggtcaaa gatgagccag
1561 actctcctcc tgtggcgctg ggcatggtag accgctcacg gattcttctg tgtgtcctca
1621 ccttcctgtg cctctccttt aaccccctga cttccctgct gcagtgggga ggggcccacg
1681 actctgacca gcacccacac tcaggctctg gccgcagtgt cctgtcattc gagtcaggtt
1741 ctgggggctg gtttgactgg atgatgccta ctcttctctt atggctggta aatggtgtga
1801 ttgtcctgag cgtctttgtg aagctgctgg ttcatgggga gccagtgatc cggccacact
1861 cgcgctcctc ggtcaccttc tggaggcacc ggaaacaggc agatctggat ctcgccagag
1921 gagattttgc agctgctgcc ggcaacctac aaacctgcct ggcagttttg ggccgggcac
1981 tgcccacctc ccgcctggac ctggcctgca gcctctcctg gaacgtgatc cgctacagcc
2041 tgcagaagct acgcctggtg cgctggctgc tcaagaaagt cttccagtgc cggcgggcca
2101 cgccagccac tgaggcaggc tttgaagacg aagctaagac cagcgcccgg gatgcggctc
2161 tggcctatca ccggctgcac cagctgcaca tcacagggaa gcttcctgca ggatccgcct
2221 gttccgatgt acacatggcg ttgtgtgccg tgaacctggc tgaatgtgca gaggagaaga
2281 tcccaccgag cacactggtt gagatccatc tgactgctgc catggggctc aagacccggt
2341 gtggaggcaa gctgggcttc ctggccagct acttcctcag ccgagcccag agcctgtgtg
2401 gccccgagca cagtgctgtt cctgactccc tgcgctggct ctgccacccc ctgggccaga
2461 agtttttcat ggagcggagc tggtctgtga agtcagctgc caaggagagt ctatactgtg
2521 cccagaggaa cccagctgac cccattgcgc aggtccacca ggccttctgc aagaacctgc
2581 tggagcgagc tatagagtcc ttggtgaaac ctcaggccaa gaagaaggct ggagaccagg
2641 aagaagagag ctgtgaattc tccagtgctc tggagtactt gaaattactt cattcttttg
2701 tggactctgt gggggttatg agccccccac tctccaggag ctccgtgctc aagtccgccc
2761 tgggtccaga catcatctgt cggtggtgga cgtctgcaat cactgtggcc atcagctggc
2821 tccagggaga cgatgcagct gtgcgctctc attttaccaa agtggaacgc atccccaagg
2881 ccctggaagt gacagagagc cccctggtga aggccatctt ccatgcctgc agagccatgc
2941 atgcctcact ccctgggaaa gcagatgggc agcagagttc cttctgccat tgcgagaggg
3001 ccagtggcca cctatggagc agcctcaacg tcagtggggc cacctctgac cctgccctca
3061 accacgtggt ccagctgctc acctgtgacc tgctactgtc gctacggaca gcgctctggc
3121 aaaaacaggc cagtgccagc caggctgtgg gggagaccta ccacgcgtca ggcgctgaac
3181 tggcgggctt ccaacgggac ctgggcagcc tgcgcaggct ggcacacagc ttccgcccag
3241 cataccgcaa ggtgttcctg catgaagcca ccgtgcgcct gatggcagga gccagcccca
3301 cccgcaccca ccagctgctg gaacacagcc tgcggcggcg caccacgcag agcaccaagc
3361 acggagaggt ggatgcctgg cccggccagc gagagcgggc caccgccatc ctgctggcct
3421 gccgccacct gcccctctcc ttcctctcct ccccgggcca gcgggcagtg ctgctggccg
3481 aagctgcccg caccctggag aaggtgggcg accggcgctc ctgcaacgac tgccagcaga
3541 tgattgttaa gctgggtggt ggcactgcca ttgccgcctc ctgaccacca ggctcagccc
3601 acccctccac ctctctctcg atttctctct ctccccctca gcatcttccc gctgagagtg
3661 gtggggagga gccttgtctt cttagctgtc acctgccgag gcttctgggc cactcaggcc
3721 agtgcacccc tgggcagagc cccttaaagc tgctgtcact agatgcccat ggtccagggc
3781 ctggtgggcg tgagaggata ggtggcaggg cagaaactgg gcagccctga cttgatagca
3841 gcagggggag ctcccaagct gccaagcccc tgcctccagc cttcctgagt ttctctctcc
3901 tgaaccctac tctctccttt ttgcttcctc agtttttatc aggctttctc tgggggacag
3961 cagtctctga gcaccaggga gcagttgccc tcaggcctgt gcccagcatg ccctcccctt
4021 tttatacgaa tgttttctac cagtgtgctt gggtttgcca tgatgcgagg ctgagttgct
4081 gtagcgtctt gattctctcc ctgggtctgc gttccctccc ctgggcctga ctgagcctgc
4141 tcattgtttt tccctttatt acacaggaca gccaggggag gaggggggcc cagccctggg
4201 aggctggtgg gaggcaggtg ggaggcaggg ggcaggcctg cggatgcatg aaataatgtt
4261 ggcattattt tttaattttt taaaaaataa atggtatctt atttaattgt cctgttcctt
4321 cccactcccc gcctcctagg atgttagccc aagctcaggg taggcccagg gggctgggag
4381 aaatgaagcc acccgtgggg actggggacc aggggccttc agcatggctt ctaggttccc
4441 tcctccccct accccatctc ctacctccac agtacagact gtccccaact taacagtggt
4501 tcaacttaaa ccatgtttca actttacaat tggtctgttg gggtattaaa tgaatttgtg
4561 acttaggata ttttcattta tgatgggttt atcaggaagt aaccccatgg taagttgagg
4621 catatctgta tatatttaaa cctaattaat tcttgagctg aaaataaata aaccaggatg
4681 gcagggacca acccctaatc cctccccagc ggcaagcccc tcttttcaga gtgggcagag
4741 ggttgcctat ggtgggcact aggaatgagg tcccctgcct cgatgcgggt cctaggagaa
4801 aaagtcctac ttttctgggt ccccaggtgc agcacctccc agagactgtt tctcccatgg
4861 cctcctgagt gatgggccct gcctccctgt gcctcatcct caggctggtt ggagcagagg
4921 gtgggcagga gccccagcac agactggggg gtgctcacag cagggccacc ttgatgcagg
4981 ctggaatgtt atccctgggg tgtgcttgga ccccacctgc tttctttctc tcctgcccct
5041 cccctactct cactgtaatt tatggaccct gcccgcctgc gtgttgtgtg tatgtcctgt
5101 gccttttctc actattgttt gggtgtggga gggggtggtt tttcactgaa aaggggggta
5161 cacctatagc tttcttgatg ttcaatcagt cactgtgtcc cagacatatt caataaacac
5221 agattggtac cacccaaaaa aaaaaaaaaa a
//