LOCUS BC051329 2661 bp mRNA linear HUM 03-JAN-2005
DEFINITION Homo sapiens protein tyrosine phosphatase, receptor type, B, mRNA
(cDNA clone IMAGE:6279463), complete cds.
ACCESSION BC051329
VERSION BC051329.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2661)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2661)
AUTHORS Director MGC Project.
TITLE Direct Submission
JOURNAL Submitted (25-APR-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Dr. Mark Watson
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 47 Row: i Column: 16
This clone was selected for full length sequencing because it
passed the following selection criteria: Similarity but not
identity to protein
This clone has the following problem: The cds is short compared to
the longest cds in the locus.
FEATURES Location/Qualifiers
source 1..2661
/db_xref="H-InvDB:HIT000053627"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:6279463"
/tissue_type="Spleen"
/clone_lib="NIH_MGC_113"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2661
/gene="PTPRB"
/gene_synonym="HPTP-BETA"
/gene_synonym="HPTPB"
/gene_synonym="PTPB"
/gene_synonym="R-PTP-BETA"
/db_xref="GeneID:5787"
/db_xref="MIM:176882"
CDS 20..2335
/gene="PTPRB"
/gene_synonym="HPTP-BETA"
/gene_synonym="HPTPB"
/gene_synonym="PTPB"
/gene_synonym="R-PTP-BETA"
/codon_start=1
/product="PTPRB protein"
/protein_id="AAH51329.1"
/db_xref="GeneID:5787"
/db_xref="MIM:176882"
/translation="MEAEFYMVILTCLIFRNSEGFQIVHVQKQQCLFKNEKVVVGSCN
RTIQNQQWMWTEDEKLLHVKSALCLAISNSSRGPSRSAILDRCSQAPRWTCYDQEGFL
EVENASLFLQKQGSRVVVKKARKYLHSWMKIDVNKEGKLVNESLCLQKAGLGAEVSVR
STRNTAPPQILTTFNAVPDGLVFLIRNTTEAFIRNAAENYSQNSSERQHPNLHMTGIT
DTSWVLSTTQPFSSTTEETGLAEPERCNFTLAESKASSHSVSIQWRILGSPCNFSLIY
SSDTLGAALCPTFRIDNTTYGCNLQDLQAGTIYNFKIISLDEERTVVLQTDPLPPARF
GVSKEKTTSTSLHVWWTPSSGKVTSYEVQLFDENNQKIQGVQIQESTSWNEYTFFNLT
AGSKYNIAITAVSGGKRSFSVYTNGSTVPSPVKDIGISTKANSLLISWSHGSGNVERY
RLMLMDKGILVHGGVVDKHATSYAFHGLTPGYLYNLTVMTEAAGLQNYRWKLVRTAPM
EVSNLKVTNDGSLTSLKVKWQRPPGNVDSYNITLSHKGTIKESRVLAPWITETHFKEL
VPGRLYQVTVSCVSGELSAQKMAVGRTFPDKVANLEANNNGRMRSLVVSWSPPAGDWE
QYRILLFNDSVVLLNITVGKEETQYVMDDTGLVPGRQYEVEVIVESGNLKNSERCQGR
TVPLAVLQLRVKHANETSLSIMWQTPVAEWEKYIISLADRDLLLIHKSLSKDAKEFTF
TDLVPGRKYMATVTSISGDLKNSSSVKGRTV"
BASE COUNT 767 a 620 c 628 g 646 t
ORIGIN
1 aacagttgct aagtggaaaa tggaggctga attttacatg gtgattctta cctgcttgat
61 cttcaggaac tcagaagggt ttcagattgt ccatgtccag aaacaacagt gtcttttcaa
121 aaatgagaaa gtggtcgtgg gctcatgcaa caggaccatc cagaaccagc agtggatgtg
181 gactgaggat gaaaagctcc ttcatgttaa atctgcactg tgcttggcca tctccaactc
241 ttcccgcggc ccctcccgct cagccatctt ggaccgctgt tcccaggcac cccgatggac
301 ctgctatgat caggaaggct tccttgaggt ggaaaatgcc tctctctttc tccagaaaca
361 aggctccaga gtagtggtca agaaggccag gaaatacctc catagctgga tgaaaataga
421 tgtcaacaag gagggaaaac tggtcaatga aagcctctgt ttacaaaaag ctggcctggg
481 agcagaagtt tcggtgagga gcactagaaa cacggctcca ccccagattc tcactacctt
541 taatgcagtt ccagatggcc tggtattcct tattaggaat accacagagg ccttcatcag
601 aaatgctgca gaaaactaca gccaaaacag cagcgagagg cagcatccca atctgcacat
661 gactggaatt acagacacat catgggtttt gtcgactact cagcccttct ccagcaccac
721 tgaagagact ggactggcgg agccagagag atgtaacttc accctggcgg agtccaaggc
781 ctccagccat tctgtgtcta tccagtggag aattttgggc tcaccctgta actttagcct
841 catctatagc agtgacaccc tgggggccgc gttgtgccct acctttcgga tagacaacac
901 cacatacgga tgtaaccttc aagatttaca agcaggaacc atctataact tcaagattat
961 ttctctggat gaagagagaa ctgtggtctt gcaaacagat cctttacctc ctgctaggtt
1021 tggagtcagt aaagagaaga cgacttcaac cagcttgcat gtttggtgga ctccttcttc
1081 cggaaaagtc acctcatatg aggtgcaatt atttgatgaa aataaccaaa agatacaggg
1141 ggttcaaatt caagaaagta cttcatggaa tgaatacact tttttcaatc tcactgctgg
1201 tagtaaatac aatattgcca tcacagctgt ttctggagga aaacgttctt tttcagttta
1261 taccaatgga tcaacagtgc catctccagt gaaagatatt ggtatttcca caaaagccaa
1321 ttctctcctg atttcctggt cccatggttc tgggaatgtg gaacgatacc ggctgatgct
1381 aatggataaa gggatcctag ttcatggcgg tgttgtggac aaacatgcta cttcctatgc
1441 ttttcacggg ctgacccctg gctacctcta caacctcact gttatgactg aggctgcagg
1501 gctgcaaaac tacaggtgga aactagtcag gacagccccc atggaagtct caaatctgaa
1561 ggtgacaaat gatggcagtt tgacctctct aaaagtcaaa tggcaaagac ctcctggaaa
1621 tgtggattct tacaatatca ccctgtctca caaagggacc atcaaggaat ccagagtatt
1681 agcaccttgg attactgaaa ctcactttaa agagttagtc cccggtcgac tttatcaagt
1741 tactgtcagc tgtgtctctg gtgaactgtc tgctcagaag atggcagtgg gcagaacatt
1801 tccagacaaa gttgcaaacc tggaggcaaa caataatggc aggatgaggt ctcttgtagt
1861 gagctggtcg ccccctgctg gagactggga gcagtatcgg atcctactct tcaatgattc
1921 tgtggtgctg ctcaacatca ctgtgggaaa ggaagaaaca cagtatgtca tggatgacac
1981 ggggctcgta ccgggaagac agtatgaggt ggaagtcatt gttgagagtg gaaatttgaa
2041 gaattctgag cgttgccaag gcaggacagt ccccctggct gtcctccagc ttcgtgtcaa
2101 acatgccaat gaaacctcac tgagtatcat gtggcagacc cctgtagcag aatgggagaa
2161 atacatcatt tccctagctg acagagacct cttactgatc cacaagtcac tctccaaaga
2221 tgccaaagaa ttcactttta ctgacctggt gcctggacga aaatacatgg ctacagtcac
2281 cagtattagt ggagacttaa aaaattcctc ttcagtaaaa ggaagaacag tgtaattgga
2341 agcaaagtca tcaagatttc cctttttagt tggacgccgt ggctcacatc tgtaatccca
2401 gcactttggg aggccgagat gggtggatct tgaggccagg aattcaagac cagcctggcc
2461 aacatggcaa gacactgtct ctactaaaaa cacaaaaatt agctgggagt ggtggcacat
2521 acctgtaatc ccagatactc gggaggctga ggcataagaa tcacttaaac ccaggaggtg
2581 gaggttgcat gagtcgagat cctgccactg cacactagcc tgggtgatag agcgagaacc
2641 tgcctcaaaa aaaaaaaaaa a
//