LOCUS BC051284 4397 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens signal transducer and activator of transcription 2,
113kDa, mRNA (cDNA clone MGC:59816 IMAGE:6460486), complete cds.
ACCESSION BC051284
VERSION BC051284.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4397)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4397)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (25-APR-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 47 Row: m Column: 7
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 38202247.
FEATURES Location/Qualifiers
source 1..4397
/db_xref="H-InvDB:HIT000053603"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:59816 IMAGE:6460486"
/tissue_type="Lung, epidermoid carcinoma"
/clone_lib="NIH_MGC_101"
/lab_host="DH10B"
/note="Vector: pOTB7"
gene 1..4397
/gene="STAT2"
/gene_synonym="ISGF-3"
/gene_synonym="MGC59816"
/gene_synonym="P113"
/gene_synonym="STAT113"
/db_xref="GeneID:6773"
/db_xref="HGNC:HGNC:11363"
/db_xref="MIM:600556"
CDS 24..2579
/gene="STAT2"
/gene_synonym="ISGF-3"
/gene_synonym="MGC59816"
/gene_synonym="P113"
/gene_synonym="STAT113"
/codon_start=1
/product="signal transducer and activator of transcription
2, 113kDa"
/protein_id="AAH51284.1"
/db_xref="GeneID:6773"
/db_xref="HGNC:HGNC:11363"
/db_xref="MIM:600556"
/translation="MAQWEMLQNLDSPFQDQLHQLYSHSLLPVDIRQYLAVWIEDQNW
QEAALGSDDSKATMLFFHFLDQLNYECGRCSQDPESLLLQHNLRKFCRDIQPFSQDPT
QLAEMIFNLLLEEKRILIQAQRAQLEQGEPVLETPVESQQHEIESRILDLRAMMEKLV
KSISQLKDQQDVFCFRYKIQAKGKTPSLDPHQTKEQKILQETLNELDKRRKEVLDASK
ALLGRLTTLIELLLPKLEEWKAQQQKACIRAPIDHGLEQLETWFTAGAKLLFHLRQLL
KELKGLSCLVSYQDDPLTKGVDLRNAQVTELLQRLLHRAFVVETQPCMPQTPHRPLIL
KTGSKFTVRTRLLVRLQEGNESLTVEVSIDRNPPQLQGFRKFNILTSNQKTLTPEKGQ
SQGLIWDFGYLTLVEQRSGGSGKGSNKGPLGVTEELHIISFTVKYTYQGLKQELKTDT
LPVVIISNMNQLSIAWASVLWFNLLSPNLQNQQFFSNPPKAPWSLLGPALSWQFSSYV
GRGLNSDQLSMLRNKLFGQNCRTEDPLLSWADFTKRESPPGKLPFWTWLDKILELVHD
HLKDLWNDGRIMGFVSRSQERRLLKKTMSGTFLLRFSESSEGGITCSWVEHQDDDKVL
IYSVQPYTKEVLQSLPLTEIIRHYQLLTEENIPENPLRFLYPRIPRDEAFGCYYQEKV
NLQERRKYLKHRLIVVSNRQVDELQQPLELKPEPELESLELELGLVPEPELSLDLEPL
LKAGLDLGPELESVLESTLEPVIEPTLCMVSQTVPEPDQGPVSQPVPEPDLPCDLRHL
NTEPMEIFRNCVKIEEIMPNGDPLLAGQNTVDEVYVSRPSHFYTDGPLMPSDF"
BASE COUNT 1081 a 1105 c 1104 g 1107 t
ORIGIN
1 ctgcaaccct aatcagagcc caaatggcgc agtgggaaat gctgcagaat cttgacagcc
61 cctttcagga tcagctgcac cagctttact cgcacagcct cctgcctgtg gacattcgac
121 agtacttggc tgtctggatt gaagaccaga actggcagga agctgcactt gggagtgatg
181 attccaaggc taccatgcta ttcttccact tcttggatca gctgaactat gagtgtggcc
241 gttgcagcca ggacccagag tccttgttgc tgcagcacaa tttgcggaaa ttctgccggg
301 acattcagcc cttttcccag gatcctaccc agttggctga gatgatcttt aacctccttc
361 tggaagaaaa aagaattttg atccaggctc agagggccca attggaacaa ggagagccag
421 ttctcgaaac acctgtggag agccagcaac atgagattga atcccggatc ctggatttaa
481 gggctatgat ggagaagctg gtaaaatcca tcagccaact gaaagaccag caggatgtct
541 tctgcttccg atataagatc caggccaaag ggaagacacc ctctctggac ccccatcaga
601 ccaaagagca gaagattctg caggaaactc tcaatgaact ggacaaaagg agaaaggagg
661 tgctggatgc ctccaaagca ctgctaggcc gattaactac cctaatcgag ctactgctgc
721 caaagttgga ggagtggaag gcccagcagc aaaaagcctg catcagagct cccattgacc
781 acgggttgga acagctggag acatggttca cagctggagc aaagctgttg tttcacctga
841 ggcagctgct gaaggagctg aagggactga gttgcctggt tagctatcag gatgaccctc
901 tgaccaaagg ggtggaccta cgcaacgccc aggtcacaga gttgctacag cgtctgctcc
961 acagagcctt tgtggtagaa acccagccct gcatgcccca aactccccat cgacccctca
1021 tcctcaagac tggcagcaag ttcaccgtcc gaacaaggct gctggtgaga ctccaggaag
1081 gcaatgagtc actgactgtg gaagtctcca ttgacaggaa tcctcctcaa ttacaaggct
1141 tccggaagtt caacattctg acttcaaacc agaaaacttt gacccccgag aaggggcaga
1201 gtcagggttt gatttgggac tttggttacc tgactctggt ggagcaacgt tcaggtggtt
1261 caggaaaggg cagcaataag gggccactag gtgtgacaga ggaactgcac atcatcagct
1321 tcacggtcaa atatacctac cagggtctga agcaggagct gaaaacggac accctccctg
1381 tggtgattat ttccaacatg aaccagctct caattgcctg ggcttcagtt ctctggttca
1441 atttgctcag cccaaacctt cagaaccagc agttcttctc caaccccccc aaggccccct
1501 ggagcttgct gggccctgct ctcagttggc agttctcctc ctatgttggc cgaggcctca
1561 actcagacca gctgagcatg ctgagaaaca agctgttcgg gcagaactgt aggactgagg
1621 atccattatt gtcctgggct gacttcacta agcgagagag ccctcctggc aagttaccat
1681 tctggacatg gctggacaaa attctggagt tggtacatga ccacctgaag gatctctgga
1741 atgatggacg catcatgggc tttgtgagtc ggagccagga gcgccggctg ctgaagaaga
1801 ccatgtctgg cacctttcta ctgcgcttca gtgaatcgtc agaagggggc attacctgct
1861 cctgggtgga gcaccaggat gatgacaagg tgctcatcta ctctgtgcaa ccgtacacga
1921 aggaggtgct gcagtcactc ccgctgactg aaatcatccg ccattaccag ttgctcactg
1981 aggagaatat acctgaaaac ccactgcgct tcctctatcc ccgaatcccc cgggatgaag
2041 cttttgggtg ctactaccag gagaaagtta atctccagga acggaggaaa tacctgaaac
2101 acaggctcat tgtggtctct aatagacagg tggatgaact gcaacaaccg ctggagctta
2161 agccagagcc agagctggag tcattagagc tggaactagg gctggtgcca gagccagagc
2221 tcagcctgga cttagagcca ctgctgaagg cagggctgga tctggggcca gagctagagt
2281 ctgtgctgga gtccactctg gagcctgtga tagagcccac actatgcatg gtatcacaaa
2341 cagtgccaga gccagaccaa ggacctgtat cacagccagt gccagagcca gatttgccct
2401 gtgatctgag acatttgaac actgagccaa tggaaatctt cagaaactgt gtaaagattg
2461 aagaaatcat gccgaatggt gacccactgt tggctggcca gaacaccgtg gatgaggttt
2521 acgtctcccg ccccagccac ttctacactg atggaccctt gatgccttct gacttctagg
2581 aaccacattt cctctgttct tttcatatct cttgcccttc ctactcctca tagcatgata
2641 ttgttctcca aggatgggaa tcaggcatgt gtcccttcca agctgtgtta actgttcaaa
2701 ctcaggcctg tgtgactcca ttggggtgag aggtgaaagc ataacatggg tacagagggg
2761 acaacaatga atcagaacag atgctgagcc ataggtctaa ataggatcct ggaggctgcc
2821 tgctgtgctg ggaggtatag gggtcctggg ggcaggccag ggcagttgac aggtacttgg
2881 agggctcagg gcagtggctt ctttccagta tggaaggatt tcaacatttt aatagttggt
2941 taggctaaac tggtgcatac tggcattggc ccttggtggg gagcacagac acaggatagg
3001 actccatttc tttcttccat tccttcatgt ctaggataac ttgctttctt ctttccttta
3061 ctcctggctc aagccctgaa tttcttcttt tcctgcaggg gttgagagct ttctgcctta
3121 gcctaccatg tgaaactcta ccctgaagaa agggatggat aggaagtaga cctctttttc
3181 ttaccagtct cctcccctac tctgccccta agctggctgt acctgttcct cccccataaa
3241 atgatcctgc caatctaatg tgagtgtgaa gctttgcaca ctagtttatg ctacctagtc
3301 tccactttct caatgcttag gagacagatc actcctggag gctggggatg gtaggattgc
3361 tggggatttt ttttttttta aacagggtct cactctgttg cccaggctag agtgcaatgg
3421 tgcaatcaca gctcactgca gcctcaacct cctgggttca agcaatcctc ctacctcagc
3481 ctcctgggta gctagcacca tggcatgcgc caccatgccc tatttttttt ttttaaagac
3541 agggtcttgc tatattgccc aggctggtct tgaactgggc tcaagtgatc ctcacgcctt
3601 ggcctcccaa agtgctggga ttataggcat gagccactgt gcttggccag gatttttttt
3661 tttttttttt ttgagatgga gtttctctct tgttgtccag gctggagtgc aatggtgtga
3721 tctcggctca ctgcaacctc cgccttccgg gttcaagtga ctctcctgcc tcagcctccc
3781 cagtagctgg gattacagat ctgcaccacc atgcccagct aattttgtat ttttagtaga
3841 gacggggttt ctccatgttg gtcaggctgg tctcgaactc ctgacctcaa gtgatctgtc
3901 cacctcggcc tcccagagtg ctgggattac aggcgtgagc cactgttccc agcaggaatt
3961 tcttttttat agtattggat aaagtttggt gtttttacag aggagaagca atgggtctta
4021 gctctttctc tattatgtta tcatcctccc ttttttgtac aatatgttgt ttacctgaaa
4081 ggaaggtttc tattcgttgg ttgtggacct ggacaaagtc caagtctgtg gaacttaaaa
4141 ccttgaaggt ctgtcatagg actctggaca atctcacacc ttagctattc ccagggaacc
4201 ccagggggca actgacattg ctccaagatg ttctcctgat gtagcttgag atataaagga
4261 aaggccctgc acaggtggct gtttcttgtc tgttatgtca gaggaacagt cctgttcaga
4321 aaggggctct tctgagcaga aatggctaat aaactttgtg ctgatctgga aaaaaaaaaa
4381 aaaaaaaaaa aaaaaaa
//