LOCUS BC050718 1455 bp mRNA linear HUM 08-OCT-2003
DEFINITION Homo sapiens polymerase (DNA directed) kappa, mRNA (cDNA clone
MGC:60331 IMAGE:5552653), complete cds.
ACCESSION BC050718
VERSION BC050718.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1455)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1455)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (08-APR-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Lou Staudt
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 110 Row: e Column: 18
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 7705343.
FEATURES Location/Qualifiers
source 1..1455
/db_xref="H-InvDB:HIT000053572"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:60331 IMAGE:5552653"
/tissue_type="Lymph, lymphoma"
/clone_lib="NIH_MGC_85"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..1455
/gene="POLK"
/gene_synonym="DINB1"
/gene_synonym="DINP"
/gene_synonym="POLQ"
/db_xref="GeneID:51426"
/db_xref="MIM:605650"
CDS 16..1434
/gene="POLK"
/gene_synonym="DINB1"
/gene_synonym="DINP"
/gene_synonym="POLQ"
/codon_start=1
/product="POLK protein"
/protein_id="AAH50718.1"
/db_xref="GeneID:51426"
/db_xref="MIM:605650"
/translation="MDSTKEKCDSYKDDLLLRMGLNDNKAGMEGLDKEKINKIIMEAT
KGSRFYGNELKKEKQVNQRIENMMQQKAQITSQQLRKAQLQVDRFAMELEQSRNLSNT
IVHIDMDAFYAAVEMRDNPELKDKPIAVGSMSMLSTSNYHARRFGVRAAMPGFIAKRL
CPQLIIVPPNFDKYRAVSKEVKEILADYDPNFMAMSLDEAYLNITKHLEERQNWPEDK
RRYFIKMGSSVENDNPGKEVNKLSEHERSISPLLFEESPSDVQPPGDPFQVNFEEQNN
PQILQNSVVFGTSAQEVVKEIRFRIEQKTTLTASAGIAPNTMLAKVCSDKNKPNGQYQ
ILPNRQAVMDFIKDLPIRKVSGIGKVTEKMLKALGIITCTELYQQRALLSLLFSETSW
HYFLHISLGLGSTHLTRDGERKSMSVERTFSEINKAEEQYSLCQELCSELAQDLQKER
LKVLYFDMVSLVFKFFNSKMLP"
misc_feature 322..639
/gene="POLK"
/gene_synonym="DINB1"
/gene_synonym="DINP"
/gene_synonym="POLQ"
/note="Region: Nucleotidyltransferase/DNA polymerase
involved in DNA repair [DNA replication, recombination,
and repair]"
/db_xref="CDD:COG0389"
misc_feature 859..1365
/gene="POLK"
/gene_synonym="DINB1"
/gene_synonym="DINP"
/gene_synonym="POLQ"
/note="IMS; Region: impB/mucB/samB family. These proteins
are involved in UV protection"
/db_xref="CDD:pfam00817"
BASE COUNT 535 a 249 c 307 g 364 t
ORIGIN
1 ggataagttt ataccatgga tagcacaaag gagaagtgtg acagttacaa agatgatctt
61 ctgcttagga tgggacttaa tgataataaa gcaggaatgg aaggattaga taaagagaaa
121 attaacaaaa ttataatgga agccacgaag gggtccagat tttatggaaa tgagctcaag
181 aaagaaaagc aagtcaacca acgaattgaa aatatgatgc aacaaaaagc tcaaatcacc
241 agccaacagc taagaaaagc acaattacag gttgacagat ttgcaatgga attagaacaa
301 agccgaaatt tgagcaatac catagtgcac attgacatgg atgctttcta tgcagctgta
361 gaaatgaggg acaatccaga attgaaggat aaacccattg ctgtaggatc aatgagtatg
421 ctgtctactt caaattacca tgcaaggaga tttggtgttc gtgcagccat gccaggattt
481 attgctaaga ggctgtgccc acaacttata atagtgcccc ccaactttga caaataccga
541 gctgtgagta aagaggttaa ggaaatactt gctgattatg atcccaattt tatggccatg
601 agtcttgatg aagcctactt gaatataaca aagcacttag aagaaagaca aaattggcct
661 gaggataaaa gaaggtattt catcaaaatg ggaagctctg tagaaaatga taatccagga
721 aaggaagtta ataaactgag tgagcatgaa cgatccatct ctccactact ttttgaagag
781 agtccttctg atgtgcagcc cccaggagat cctttccaag tgaactttga agaacaaaac
841 aatcctcaaa tactccaaaa ctcagttgtt tttggaacat cagcccagga agtggtaaag
901 gaaattcgtt tcagaattga gcagaaaaca acactgacag ccagtgcagg cattgcccca
961 aatacaatgt tagcaaaagt atgcagtgat aagaataaac caaatggaca ataccaaatt
1021 cttcccaata gacaagctgt gatggacttc atcaaggatt tacccattag aaaggtttct
1081 ggaataggaa aagttacaga gaaaatgtta aaggcccttg gaattattac atgtacagaa
1141 ctttaccaac agagggcatt gctttctctc cttttctctg aaacatcttg gcattatttc
1201 cttcatatct ccttgggtct aggttcaaca cacctgacga gggatggaga gaggaaaagt
1261 atgagcgttg agaggacatt cagtgagata aataaagcgg aagagcaata cagcctatgt
1321 caagaacttt gcagtgagct tgctcaggat ctacagaaag aaagacttaa ggtgctttat
1381 tttgatatgg tgtccttagt ttttaagttt tttaatagta aaatgctacc ttaaaagcta
1441 aaaaaaaaaa aaaaa
//