LOCUS BC050558 3300 bp mRNA linear HUM 19-MAR-2007
DEFINITION Homo sapiens RAB5B, member RAS oncogene family, mRNA (cDNA clone
MGC:57705 IMAGE:6191566), complete cds.
ACCESSION BC050558
VERSION BC050558.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3300)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3300)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (08-APR-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Dr. James R. Lupski
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 107 Row: n Column: 8
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 33943097.
FEATURES Location/Qualifiers
source 1..3300
/db_xref="H-InvDB:HIT000099221"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:57705 IMAGE:6191566"
/tissue_type="Peripheral Nervous System, sympathetic
trunk"
/clone_lib="Lupski_sympathetic_trunk"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..3300
/gene="RAB5B"
/db_xref="GeneID:5869"
/db_xref="HGNC:HGNC:9784"
/db_xref="MIM:179514"
CDS 136..783
/gene="RAB5B"
/codon_start=1
/product="RAB5B, member RAS oncogene family"
/protein_id="AAH50558.2"
/db_xref="GeneID:5869"
/db_xref="HGNC:HGNC:9784"
/db_xref="MIM:179514"
/translation="MTSRSTARPNGQPQASKICQFKLVLLGESAVGKSSLVLRFVKGQ
FHEYQESTIGAAFLTQSVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDI
TNQETFARAKTWVKELQRQASPSIVIALAGNKADLANKRMVEYEEAQAYADDNSLLFM
ETSAKTAMNVNDLFLAIAKKLPKSEPQNLGGAAGRSRGVDLHEQSQQNKSQCCSN"
BASE COUNT 796 a 850 c 738 g 916 t
ORIGIN
1 gttcgacaca ggcttggggc cgacggggga gacggagccc caggagtgtt gaagcctgga
61 aatcccctcc ccttccccct ccccccttta cagtatcccc ctccctccac cctttcccat
121 tctgataatc tggccatgac tagcagaagc acagctaggc ccaatgggca accccaggcc
181 agcaaaattt gccagttcaa attggtcctg ctgggagaat ctgcagtggg aaagtcaagc
241 ctggtattac gttttgtcaa agggcagttc catgagtacc aggagagcac cattggagcg
301 gccttcctca cccagtccgt ttgtctagat gacacaacag tgaagtttga gatctgggac
361 acagctgggc aggagcgata tcacagctta gcccccatgt actacagggg tgcccaagct
421 gcaatcgtgg tttacgacat tactaatcag gaaacctttg cccgagcaaa gacatgggtg
481 aaggaactac agcgacaggc cagtcctagc atcgttattg ccctggcagg gaacaaagct
541 gacctggcca acaaacgtat ggtggagtat gaagaggccc aggcatatgc agatgacaac
601 agcttattgt tcatggagac ttcagccaag acagctatga acgtgaatga tctcttcctg
661 gcaatagcta agaagttgcc aaagagtgaa ccccagaatc tgggaggtgc agcaggccga
721 agccggggtg tggatctcca tgaacagtcc cagcagaaca agagccagtg ttgtagcaac
781 tgagggggtg gctagcagca aacaagtatg gagctagcac aagagctaag aaataacctc
841 catccctacc cctcagcaca caacccctac ggtaacagca cactgagccc tggctcccaa
901 gggctgcctc ctgacagctc cgtcatggca ctttttaacg cttcagcaac aaacaccagg
961 cagctgttgc cactggcctc ctacccccta ctctggggct tgggggtcaa ctccccccag
1021 gacttacctt ccaaaacaaa ctttcttcac tttgtattat aggtacaaga cagcgactta
1081 cgtatctttt ctcctcctcc ctagtgttcc tccccatttt ttcagaaaac acttctgact
1141 cctgtccctt ccccttctgc ttttggtcag tccctgttct tgagcctctt ttctcctctc
1201 cccaggatgc agaaagtggt gaacccagga actgaggaag gaggtttcca gttcatttac
1261 attaagggcc ctgggggaga ataaagctca gagcaggagg gagtaaggaa acatttcctt
1321 tttgttttta tttggttgga gtttctcata tttgaaaaca ttgcggtatc catgatttgg
1381 ccttgtggag ggtgttccta ggtagaggtg agaatgggga ggcaagatct caggcaccag
1441 gcaggaggtg ccttgtaagc taactgggcg gaggtggagg tgcagtgtca actgtggctc
1501 tgtaactctt caaaggccca gtttcccctc acgcagcctc ttaggtagcg tttcccctaa
1561 tcgtgggggt tggaccccag agtcttccaa agaattttca ctggttgcct gcatctttgg
1621 ctctgctgtg atctgattgg aggagggaca gtttctggta cccatcctct gatttataca
1681 tatgcatttt ttcccctctg gcctttagat ggcctcagcc ccagccacca tatacccctg
1741 cagtttgcac tttaattgat ggtagttcag ttggggtact tgttttatgg aagttttgat
1801 tgatttactt gccctcccac cttcttttta attcaatgaa atctgaggtt aatgcgaggt
1861 tcgaggagag gttatagata aaactaccag tggcagctac tcaagtccta tctccactgt
1921 tagcttcctc caactctaat tattaaccta tattcttgcc aagctaacta ttgactatag
1981 gtttgccttt cctggagaat taattgagca attgaggagt gtctcaggat agcacaggcc
2041 aaggtagggg agtaaaaagg aggtcaggca aaagggagga gttttctgtc ctttcccagg
2101 tttcacactc aatttgatat ccattaccat gtcttttcta cttccttgta aataggtatg
2161 atctttattc ccactgtaca gtctgttcta tcctctgcct cccatcaggc cctgtttctt
2221 tgttcctttg ttaatatctt gaatttagtc cctccatcct taatcccccc atccctcccc
2281 atcatgcaac cagtggttta atccatgtac caataggggc tagtaccaca gaggcctcct
2341 gtggtgccct cgtatcatac cacctgttcc tgtggagagg gaatgaccgg cactgaaggt
2401 accttacaac tggctcatat tatcagagga ccttggtcct ttctaaatct ctagtctctc
2461 ttcatatcct tcatcaggtg ttttaagatg tctctgagaa gccatcaagg caaaagagaa
2521 ctttaagttc cttgttccag cccggagttt tgggaaagaa agaaaggaaa ggtcacagtg
2581 acctaggatt ggaaccttcc tgcccttttg gcttgcagac tgccttctat cccagaacag
2641 ctgagaaatc tatgaagctg agattctgaa ggacccagct taggttcttc cacttaggcc
2701 tcaattccct tccttttcca ggggcagcct tagttcccat ggccctgaaa cacacacatt
2761 tcccccttcc tttcccagaa gccactggcc ccccatagca cccagtgcat cctttttaca
2821 agtggaagaa ctaggatggc tttccaaagt cttctagaaa tgaagttctt tctctgtgca
2881 gctttccccc ttggagcagg agtgaagatg tttcattatc ttgggcctgg gaaaccactt
2941 ccccaggctt ctccctcccc ccacccccat aggaacagga tttggcctta gcttctgggc
3001 ctatcggctg ccttccctct acttcctacc acctcttctg ccttcctttg agctctgttg
3061 ggcttgggga tcttagtttt cttttgttta tttcccagct catttttttc ttctggtcag
3121 tttttttaag ggggggtgtt gtggtttttt gtttttgttt tgcttctgag aaagcatttg
3181 cctttcttcc tctcccaaca taacaatcgt ggtaacagaa tgcgactgct gatttaccga
3241 tgtatttaat gtaagtaaaa aaaggaaaaa aagaaaaaaa aaaaaaaaaa aaaaaaaaaa
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