LOCUS BC050557 4427 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens timeless homolog (Drosophila), mRNA (cDNA clone
MGC:57696 IMAGE:5574624), complete cds.
ACCESSION BC050557
VERSION BC050557.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4427)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4427)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (08-APR-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 107 Row: g Column: 13
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 52851463.
FEATURES Location/Qualifiers
source 1..4427
/db_xref="H-InvDB:HIT000053496"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:57696 IMAGE:5574624"
/tissue_type="Duodenum, adenocarcinoma"
/clone_lib="NIH_MGC_88"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..4427
/gene="TIMELESS"
/gene_synonym="hTIM"
/gene_synonym="TIM"
/gene_synonym="TIM1"
/db_xref="GeneID:8914"
/db_xref="HGNC:HGNC:11813"
/db_xref="MIM:603887"
CDS 196..3822
/gene="TIMELESS"
/gene_synonym="hTIM"
/gene_synonym="TIM"
/gene_synonym="TIM1"
/codon_start=1
/product="timeless homolog (Drosophila)"
/protein_id="AAH50557.1"
/db_xref="GeneID:8914"
/db_xref="HGNC:HGNC:11813"
/db_xref="MIM:603887"
/translation="MDLHMMNCELLATCSALGYLEGDTYHKEPDCLESVKDLIRYLRH
EDETRDVRQQLGAAQILQSDLLPILTQHHQDKPLFDAVIRLMVNLTQPALLCFGNLPK
EPSFRHHFLQVLTYLQAYKEAFASEKAFGVLSETLYELLQLGWEERQEEDNLLIERIL
LLVRNILHVPADLDQEKKIDDDASAHDQLLWAIHLSGLDDLLLFLASSSAEEQWSLHV
LEIVSLMFRDQNPEQLAGVGQGRLAQERSADFAELEVLRQREMAEKKTRALQRGNRHS
RFGGSYIVQGLKSIGERDLIFHKGLHNLRNYSSDLGKQPKKVPKRRQAARELSIQRRS
ALNVRLFLRDFCSEFLENCYNRLMGSVKDHLLREKAQQHDETYYMWALAFFMAFNRAA
SFRPGLVSETLSVRTFHFIEQNLTNYYEMMLTDRKEAASWARRMHLALKAYQELLATV
NEMDISPDEAVRESSRIIKNNIFYVMEYRELFLALFRKFDERCQPRSFLRDLVETTHL
FLKMLERFCRSRGNLVVQNKQKKRRKKKKKVLDQAIVSGNVPSSPEEVEAVWPALAEQ
LQCCAQNSELSMDSVVPFDAASEVPVEEQRAEAMVRIQDCLLAGQAPQALTLLRSARE
VWPEGDVFGSQDISPEEEIQLLKQILSAPLPRQQGPEERGAEEEEEEEEEEEEELQVV
QVSEKEFNFLDYLKRFACSTVVRAYVLLLRSYQQNSAHTNHCIVKMLHRLAHDLKMEA
LLFQLSVFCLFNRLLSDPAAGAYKELVTFAKYILGKFFALAAVNQKAFVELLFWKNTA
VVREMTEGYGSLDDRSSSRRAPTWSPEEEAHLRELYLANKDVEGQDVVEAILAHLNTV
PRTRKQIIHHLVQMGLADSVKDFQRKGTHIVLWTGDQELELQRLFEEFRDSDDVLGHI
MKNITAKRSRARIVDKLLALGLVAERRELYKKRQKKLASSILPNGAESLKDFCQEDLE
EEENLPEEDSEEEEEGGSEAEQVQGSLVLSNENLGQSLHQEGFSILLLWLQNCLIRAA
DDREEDGCSQAVPLVPLTEENEEAMENEQFQQLLRKLGVRPPASGQETFWRIPAKLSP
TQLRRAAASLSQPEEEQKLQPELQPKVPGEQGSDEEHCKEHRAQALRALLLAHKKKAG
LASPEEEDAVGKEPLKAAPKKRQLLDSDEEQEEDEGRNRAPELGAPGIQKKKRYQIED
DEDD"
BASE COUNT 1110 a 1073 c 1243 g 1001 t
ORIGIN
1 actagttcta gctcgcgatc tagaactagc gacccacgcg tccgggtcca gctgagcctg
61 gtggcggaaa ggctgcggcc ccgcgccaga gggccggtgg ctcctccggg cttctgagga
121 cccgcaggga gcgggcctca tcatttctgt ctcctgtttc tccacttcct tctctattgg
181 ttggtccact gatgtatgga cttgcacatg atgaactgtg aacttctagc cacatgtagt
241 gcccttgggt acttggaggg agacacttac cataaggaac cagattgctt agagagcgtg
301 aaggatctca tccgctattt gaggcatgag gatgagacac gagatgtgcg gcagcagctg
361 ggggcagccc agatcctaca gagcgacctt ctgcccatcc tcacccagca ccaccaggac
421 aagcctctct ttgatgctgt tatcagactg atggtgaact tgacacaacc agccttgctc
481 tgttttggca atctgcctaa ggagcccagc tttcggcacc attttttgca ggtgctaact
541 tatttgcagg cctacaaaga ggcctttgcc agtgagaagg cttttggagt cctcagtgaa
601 accttgtatg agctgctgca gctgggctgg gaggaacggc aggaggaaga caacttgctg
661 attgaacgga tcctactgct ggtcagaaat attctccatg tcccagctga ccttgatcag
721 gagaagaaga ttgatgatga cgccagtgcc catgaccagc tcctctgggc gattcacctc
781 agcggcctgg atgacctgct cctctttctg gccagctcgt ctgctgagga gcaatggagc
841 ctacatgtgc tagagattgt ctcccttatg tttcgtgacc agaaccccga gcagctggcg
901 ggagtagggc agggacgctt agctcaggag cggagtgcag attttgcaga actggaggtg
961 ttgcgccagc gagagatggc agaaaagaag actcgagccc tccagcgagg caacaggcat
1021 tctcgatttg ggggctccta tattgtccag gggttgaaat ccattgggga gagggacctc
1081 atctttcaca aaggccttca caacctacga aactacagtt cagatttggg aaagcagccg
1141 aaaaaggtgc ctaaacgtcg ccaggccgcc cgagagctgt ccattcagcg ccgttctgcc
1201 ctcaatgtga ggctcttcct cagagacttc tgctctgagt tcctggagaa ctgttacaac
1261 cggctcatgg gatcagtaaa ggatcacctg cttcgggaga aagctcagca gcatgatgag
1321 acctattata tgtgggcctt ggctttcttc atggccttca accgagctgc ctccttccgg
1381 ccaggcctgg tttctgagac cctcagtgtc cgtaccttcc acttcattga gcagaacctc
1441 accaactact atgagatgat gctgactgac cgcaaggaag ctgcctcctg ggcacgccgg
1501 atgcacttgg ctctgaaggc ctatcaggag ctgctggcaa cagtgaatga gatggacata
1561 tctccagatg aggctgtgag ggagagcagc cgcatcatca agaacaatat tttctatgtg
1621 atggagtacc gagaactatt cctggcactt tttcgaaagt ttgatgagag atgccagccc
1681 cgctctttcc ttcgtgacct ggtggagacc acccacctct tcctcaaaat gttggagcga
1741 ttctgtcgga gccgtgggaa cctggtggtg cagaacaaac aaaagaagag aaggaagaag
1801 aagaagaagg tcctagacca ggccattgtt tctggtaatg tcccatctag cccagaagaa
1861 gtggaggctg tgtggccagc cctggctgag cagctacagt gctgtgccca gaattctgag
1921 ctcagcatgg actccgtggt tccctttgat gcggcctcag aggtgccagt ggaggagcag
1981 cgggcagaag ctatggtacg gatccaagac tgtctcctgg ctggccaggc cccacaggcc
2041 ctgactctcc tgaggtctgc tcgggaggtg tggcctgaag gagatgtgtt tggctctcaa
2101 gacatttctc cagaggaaga gatccagttg ctgaaacaaa tcctctctgc tccacttccc
2161 cggcagcagg gcccagagga acgtggggca gaggaagaag aagaggagga ggaggaggaa
2221 gaggaggagt tgcaagtggt ccaggtgtcg gagaaagaat ttaattttct ggactacctg
2281 aaacgctttg catgttcaac tgtcgttcga gcctatgtgc tgctactaag gagctaccag
2341 cagaatagtg cccacactaa ccattgcatt gtgaagatgc tgcaccggct ggcccatgac
2401 ctcaaaatgg aagccctact ttttcagctg tcagtcttct gcctcttcaa tcgtctgctt
2461 agtgaccctg ctgctggagc ctacaaagag ctagtgactt ttgccaaata catcctgggc
2521 aaattttttg cactggctgc agtcaaccaa aaagcctttg tggagctgtt gttctggaag
2581 aacacagctg tggttcgaga gatgactgag ggctatggct ccctggatga caggtcttcc
2641 agtcgcagag cacctacatg gagccccgaa gaagaggctc atcttcggga gctgtacctc
2701 gccaataagg acgtggaagg gcaggatgtg gtggaagcca tcttggccca cctgaatact
2761 gttcctcgaa cacgcaagca gatcatccac catctggtac agatgggact ggctgacagt
2821 gtcaaggact tccaaaggaa aggaacccat attgtactgt ggacggggga tcaggagttg
2881 gagctgcagc ggctttttga ggaattccgg gactcagatg atgtcctggg tcatatcatg
2941 aagaatatca cagccaaacg ctcacgggcc cgaatagtgg ataaactctt ggctctgggg
3001 ctggtggctg agcggcggga gctgtacaag aaacggcaga aaaagttggc atcctccatc
3061 ttgccaaatg gagcggagtc cctgaaagat ttttgccagg aagatctgga agaagaggaa
3121 aacctgcctg aggaagacag cgaagaggaa gaagaagggg gctcagaagc agaacaagtc
3181 cagggtagct tagtcctttc aaatgaaaac cttggtcaaa gcctgcatca ggaaggcttt
3241 tctatcctgc tcctatggct ccagaactgc ctgatccgag cagctgatga tcgggaagag
3301 gatggctgct cccaggccgt tccattggtg ccactcacag aggaaaatga ggaagccatg
3361 gaaaacgaac agtttcagca gctgttgcgc aagctagggg ttcggccccc tgcctctggg
3421 caggaaacct tctggcgaat tccagccaag ctgagtccta cccagctccg gagggcagca
3481 gcttctttga gtcaaccaga ggaggaacag aagctgcagc cagagctgca gcctaaagtc
3541 cctggagagc aaggctctga tgaggagcac tgtaaagagc accgagcaca agccctgagg
3601 gccctcttgc tagcccacaa gaagaaagcg ggcctggcat ccccagagga ggaagacgct
3661 gttggtaaag agccgctgaa ggcagcaccc aagaaacgac aattgctgga cagcgacgag
3721 gaacaggaag aagatgaggg caggaacaga gcaccagagt tgggagctcc aggaatccaa
3781 aagaagaaac gataccagat tgaggatgat gaggatgact gaagagctaa gaagcctagg
3841 ggtagagata gacacgtttt tagatggtgc attcaagtca gagttggaag ggtcatacag
3901 gacccagaag ctcctcttac tggacagagc agtagaatcc caggctcttt cacggattta
3961 ggctgagaaa cttcagcagc agtattggac ttctctgctg tcagtctttg tttctcccag
4021 tttttatcgg tatgccccag cagctctctg gagatttagt tctcttcttc taggaaccat
4081 ttcttttggt tattggagct ccttagcaaa taagaggagt gagtgaaata gagaaagcac
4141 cccggacccc ttttattggt ctgttccttt ggctttctct tggaggtggg tcgcagcacc
4201 agatggggag ctttatgaca tgacaggcgg gagttttgta ccacttttag aagataccag
4261 atgcctctgt cctcattttg tttcctatga tcatcctcta gataccagat agaggcccat
4321 tcctgcattt gagatagggt tggaatatag tactctagat gatgaatgtg tttgctttgt
4381 gtttggtatt aaacatgtaa gattagaagt tcaaaaaaaa aaaaaaa
//