LOCUS BC050553 4471 bp mRNA linear HUM 27-OCT-2006
DEFINITION Homo sapiens patatin-like phospholipase domain containing 6, mRNA
(cDNA clone MGC:57655 IMAGE:5741213), complete cds.
ACCESSION BC050553
VERSION BC050553.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4471)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4471)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (08-APR-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 107 Row: h Column: 2
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 31543298.
FEATURES Location/Qualifiers
source 1..4471
/db_xref="H-InvDB:HIT000053493"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:57655 IMAGE:5741213"
/tissue_type="Duodenum, adenocarcinoma"
/clone_lib="NIH_MGC_88"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..4471
/gene="PNPLA6"
/gene_synonym="NTE"
/gene_synonym="sws"
/db_xref="GeneID:10908"
/db_xref="HGNC:HGNC:16268"
/db_xref="MIM:603197"
CDS 247..4230
/gene="PNPLA6"
/gene_synonym="NTE"
/gene_synonym="sws"
/codon_start=1
/product="patatin-like phospholipase domain containing 6"
/protein_id="AAH50553.1"
/db_xref="GeneID:10908"
/db_xref="HGNC:HGNC:16268"
/db_xref="MIM:603197"
/translation="MEAPLQTGMVLGVMIGAGVAVVVTAVLILLVVRRLRVPKTPAPD
GPRYRFRKRDKVLFYGRKIMRKVSQSTSSLVDTSVSATSRPRMRKKLKMLNIAKKILR
IQKETPTLQRKEPPPAVLEADLTEGDLANSHLPSEVLYMLKNVRVLGHFEKPLFLELC
RHMVFQRLGQGDYVFRPGQPDASIYVVQDGLLELCLPGPDGKECVVKEVVPGDSVNSL
LSILDVITGHQHPQRTVSARAARDSTVLRLPVEAFSAVFTKYPESLVRVVQIIMVRLQ
RVTFLALHNYLGLTNELFSHEIQPLRLFPSPGLPTRTSPVRGSKRMVSTSATDEPRET
PGRPPDPTGAPLPGPTGDPVKPTSLETPSPPLLSRCVSMPGDISGLQGGPRSDFDMAY
ERGRISVSLQEEASGGSLAAPARTPTQEPREQPAGACEYSYCEDESATGGCPFGPYQG
RQTSSIFEAAKQELAKLMRIEDPSLLNSRVLLHHAKAGTIIARQGDQDVSLHFVLWGC
LHVYQRMIDKAEDVCLFVAQPGELVGQLAVLTGEPLIFTLRAQRDCTFLRISKSDFYE
IMRAQPSVVLSAAHTVAARMSPFVRQMDFAIDWTAVEAGRALYRQGDRSDCTYIVLNG
RLRSVIQRGSGKKELVGEYGRGDLIGVVEALTRQPRATTVHAVRDTELAKLPEGTLGH
IKRRYPQVVTRLIHLLSQKILGNLQQLQGPFPAGSGLGVPPHSELTNPASNLATVAIL
PVCAEVPMVAFTLELQHALQAIGPTLLLNSDIIRARLGASALDSIQEFRLSGWLAQQE
DAHRIVLYQTDASLTPWTVRCLRQADCILIVGLGDQEPTLGQLEQMLENTAVRALKQL
VLLHREEGAGPTRTVEWLNMRSWCSGHLHLRCPRRLFSRRSPAKLHELYEKVFSRRAD
RHSDFSRLARVLTGNTIALVLGGGGARGCSHIGVLKALEEAGVPVDLVGGTSIGSFIG
ALYAEERSASRTRQRAREWAKSMTSVLEPVLDLTYPVTSMFTGSAFNRSIHRVFQDKQ
IEDLWLPYFNVTTDITASAMRVHKDGSLWRYVRASMTLSGYLPPLCDPKDGHLLMDGG
YINNLPADIARSMGAKTVIAIDVGSQDETDLSTYGDSLSGWWLLWKRLNPWADKVKVP
DMAEIQSRLAYVSCVRQLEVVKSSSYCEYLRPPIDCFKTMDFGKFDQIYDVGYQYGKA
VFGGWSRGNVIEKMLTDRRSTDLNESRRADVLAFPSSGFTDLAEIVSRIEPPTSYVSD
GCADGEESDCLTEYEEDAGPDCSRDEGGSPEGASPSTASEMEEEKSILRQRRCLPQEP
PGSATDA"
BASE COUNT 867 a 1443 c 1380 g 781 t
ORIGIN
1 gcggaacgct agcggtgttg gcgcggagtg gaccccggct gcggcccctg gcaatggcgc
61 caccatcggt cccggagtcc cagtgatgct ctgtgccata gagcccccat aacttcacta
121 ctacgtgata gtaaatcccc ggcaaaaacc agcagcgcct tgcaagccca cgccacccca
181 agcatcccag gactcttctg aaacgactcc gggctaccag atcggccgtc cagctggaat
241 caaccgatgg aggctccgct gcaaactgga atggtgcttg gcgtgatgat cggggccgga
301 gtggcggtgg tggtcacggc cgtgctcatc ctcctggtgg tgcggaggct gcgagtgcca
361 aaaaccccag ccccggatgg cccccggtat cggttccgga agagggacaa agtgctcttc
421 tatggccgga agattatgcg gaaggtgtca caatccacct cctccctcgt ggatacctct
481 gtctccgcca cctcccggcc acgcatgagg aagaaactga agatgctcaa cattgccaag
541 aagatcctgc gcatccagaa agagacgccc acgctgcagc ggaaggagcc cccgcccgca
601 gtgctagaag ctgacctgac cgagggcgac ctggctaact cccatctgcc ctctgaagtg
661 ctttatatgc tcaagaacgt ccgggtgctg ggccacttcg agaagccact cttcctggag
721 ctctgccgcc acatggtctt ccagcggctg ggccagggtg actacgtctt ccggccgggc
781 cagccagatg ccagcatcta cgtggtgcag gacgggctgc tggagctctg tctgccaggg
841 cctgacggga aggagtgtgt ggtgaaggaa gtggttcctg gggacagcgt caacagcctt
901 ctcagcatcc tggatgtcat caccggtcac cagcatcccc agcggaccgt gtctgcccgg
961 gcggcccggg actccacggt gctgcgcctg ccggtggaag cattctccgc ggtcttcacc
1021 aagtacccgg agagcttggt gcgggtcgtg cagatcatca tggtgcggct gcagcgagtc
1081 accttcctgg cactgcacaa ctacctgggt ctgaccaatg agctcttcag ccacgagatc
1141 cagcccctgc gtctgttccc cagccccggc ctcccaactc gcaccagccc tgtgcggggc
1201 tccaagagaa tggtcagcac ctcagctaca gacgagccca gggagacccc agggcggcca
1261 cccgatccca ccggggcccc gctgcctgga cctacagggg accctgtgaa gcccacatcc
1321 ctggaaaccc cctcgccccc tctgctgagc cgctgcgtct ccatgccagg ggacatctca
1381 ggcttgcagg gtggcccccg ctccgacttc gacatggcct atgagcgtgg ccggatctcc
1441 gtgtccctgc aagaagaggc ctccgggggg tccctggcag cccccgctcg gacccccact
1501 caggagcctc gtgagcagcc ggcaggcgcc tgtgaataca gctactgtga ggatgagtcg
1561 gccactggtg gctgcccttt cgggccctac cagggccgcc agaccagcag catcttcgag
1621 gcagcaaagc aggagctggc caagctgatg cggattgagg acccctccct cctgaacagc
1681 agagtcttgc tgcaccacgc caaagctggc accatcattg cccgccaggg agaccaggac
1741 gtgagcctgc acttcgtgct ctggggctgc ctgcacgtgt accagcgcat gatcgacaag
1801 gcggaggacg tgtgcctgtt cgtagcgcag cccggggaac tggtggggca gctggcggtg
1861 ctcactggcg aacctctcat cttcacactg cgagcccaac gcgactgcac cttcctgcgg
1921 atctccaagt ccgacttcta tgagatcatg cgcgcacagc ccagtgtggt gctgagtgcg
1981 gcgcacacgg tggcagccag gatgtcgccc ttcgtgcgcc agatggactt cgccatcgac
2041 tggactgcag tggaggcggg acgcgcgctg tacaggcagg gcgaccgctc cgactgcact
2101 tacatcgtgc tcaatgggcg gctgcgtagc gtgatccagc gaggcagtgg caagaaggag
2161 ctggtgggcg agtacggccg cggcgacctc atcggcgtgg tggaggcact gacccggcag
2221 ccgcgagcca cgacggtgca cgcggtgcgc gacacggagc tggccaagct tcccgagggc
2281 accttgggtc acatcaaacg ccggtacccg caggtcgtga cccgccttat ccacctactg
2341 agccagaaaa ttctagggaa tttgcagcag ctgcaaggac ccttcccagc aggctctggg
2401 ttgggtgtgc ccccacactc ggaactcacc aacccagcca gcaacctggc aactgtggca
2461 atcctgcctg tgtgtgctga ggtccccatg gtggccttca cgctggagct gcagcacgcc
2521 ctgcaggcca tcggtccgac gctactcctt aacagtgaca tcatccgggc acgcctgggg
2581 gcctccgcac tggatagcat ccaagagttc cggctgtcag ggtggctggc ccagcaggag
2641 gatgcacacc gtatcgtact ctaccagacg gacgcctcgc tgacgccctg gaccgtgcgc
2701 tgcctgcgac aggccgactg catcctcatt gtgggcctgg gggaccagga gcctaccctc
2761 ggccagctgg agcagatgct ggagaacacg gctgtgcgcg cccttaagca gctagtcctg
2821 ctccaccgag aggagggcgc gggccccacg cgcaccgtgg agtggctaaa tatgcgcagc
2881 tggtgctcgg ggcacctgca cctgcgctgt ccgcgccgcc tcttttcgcg ccgcagccct
2941 gccaagctgc atgagctcta cgagaaggtt ttctccaggc gcgcggaccg gcacagcgac
3001 ttctcccgct tggcgagggt gctcacgggg aacaccattg cccttgtgct aggcgggggc
3061 ggggccaggg gctgctcgca catcggagta ctaaaggcat tagaggaggc gggggtcccc
3121 gtggacctgg tgggcggcac gtccattggc tctttcatcg gagcgttgta cgcggaggag
3181 cgcagcgcca gccgcacgag gcagcgggcc cgggagtggg ccaagagcat gacttcggtg
3241 ctggaacctg tgttggacct cacgtaccca gtcacctcca tgttcactgg gtctgccttt
3301 aaccgcagca tccatcgggt cttccaggat aagcagattg aggacctgtg gctgccttac
3361 ttcaacgtga ccacagatat caccgcctca gccatgcgag tccacaaaga tggctccctg
3421 tggcggtacg tgcgcgccag catgacgctg tcgggctacc tgcccccgct gtgcgacccc
3481 aaggacgggc acctactcat ggatggcggc tacatcaaca atctgccagc ggacatcgcc
3541 cgcagcatgg gtgccaaaac ggtcatcgcc attgacgtgg ggagccagga tgagacggac
3601 ctcagcacct acggggacag cctgtccggc tggtggctgc tgtggaagcg gctgaatccc
3661 tgggctgaca aggtaaaggt tccagacatg gctgaaatcc agtcccgcct ggcctacgtg
3721 tcctgtgtgc ggcagctaga ggttgtcaag tccagctcct actgcgagta cctgcgcccg
3781 cccatcgact gcttcaagac catggacttt gggaagttcg accagatcta tgatgtgggc
3841 taccagtacg ggaaggcggt gtttggaggc tggagccgtg gcaacgtcat tgagaaaatg
3901 ctcacagacc ggcggtctac agaccttaat gagagccgcc gtgcagacgt gcttgccttc
3961 ccaagctctg gcttcactga cttggcagag attgtgtccc ggattgagcc ccccacgagc
4021 tatgtctctg atggctgtgc tgacggagag gagtcagatt gtctgacaga gtatgaggag
4081 gacgccggac ccgactgctc gagggatgaa ggggggtccc ccgagggcgc aagccccagc
4141 actgcctccg agatggagga ggagaagtcg attctccggc aacgacgctg tctgccccag
4201 gagccgcccg gctcagccac agatgcctga ggacctcgac aggggtcacc ccctccctcc
4261 cacccctgga ctgggctggg ggtggccccg tgggggtagc tcactccccc tcctgctgct
4321 atgcctgtga cccccgcggc ccacacactg gactgacctg ccctgagcgg ggatgcagtg
4381 ttgcactgat gacttgacca gcccctcccc caataaactc gcctcttgga aaaaaaaaaa
4441 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa a
//