LOCUS BC050521 4930 bp mRNA linear HUM 11-APR-2003
DEFINITION Homo sapiens, Rho guanine nucleotide exchange factor (GEF) 7, clone
IMAGE:4508752, mRNA, partial cds.
ACCESSION BC050521
VERSION BC050521.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4930)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (08-APR-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 107 Row: b Column: 4
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 22027526.
FEATURES Location/Qualifiers
source 1..4930
/db_xref="H-InvDB:HIT000099213"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:4508752"
/tissue_type="Testis, embryonal carcinoma"
/clone_lib="NIH_MGC_92"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
CDS <1..2297
/codon_start=3
/product="Rho guanine nucleotide exchange factor (GEF) 7"
/protein_id="AAH50521.1"
/db_xref="GeneID:8874"
/translation="WWKVRRSKKTTTSFPISRSGLFGVYYVEVHQPALPWRQEAFFCS
RTFDANDLYQGQNFNKVLSSLVTLNKVTADIGLGSDSVCARPSSHRIKSFDSLGSQSL
HTRTSKLFQGQYRSLDMTDNSNNQLVVRAKFNFQQTNEDELSFSKGDVIHVTRVEEGG
WWEGTLNGRTGWFPSNYVREVKASEKPVSPKSGTLKSPPKGFDTTAINKSYYNVVLQN
ILETENEYSKELQTVLSTYLRPLQTSEKLSSANISYLMGNLEEICSFQQMLVQSLEEC
TKLPEAQQRVGGCFLNLMPQMKTLYLTYCANHPSAVNVLTEHSEELGEFMETKGASSP
GILVLTTGLSKPFMRLDKYPTLLKELERHMEDYHTDRQDIQKSMAAFKNLSAQCQEVR
KRKELELQILTEAIRNWEGDDIKTLGNVTYMSQVLIQCAGSEEKNERYLLLFPNVLLM
LSASPRMSGFIYQGKLPTTGMTITKLEDSENHRNAFEISGSMIERILVSCNNQQDLQE
WVEHLQKQTKVTSVGNPTIKPHSVPSHTLPSHPVTPSSKHADSKPAPLTPAYHTLPHP
SHHGTPHTTTNWGPLEPPKTPKPWSLSCLRPAPPLRPSAALCYKEDLSKSPKTMKKLL
PKRKPERKPSDEEFASRKSTAALEEDAQILKVIEAYCTSAKTRQTLNSSSRKESAPQV
LLPEEEKIIVEETKSNGQTVIEEKSLVDTVYALKDEVQELRQDNKKMKKSLEEEQRAR
KDLEKLVRKVLKNMNDPAWDETNL"
BASE COUNT 1303 a 1217 c 1170 g 1240 t
ORIGIN
1 gatggtggaa agtgaggaga agcaaaaaga cgactacttc tttccccatt tcccggtctg
61 gtctttttgg ggtctactac gtagaggtgc atcagccagc gctaccatgg aggcaggagg
121 cattcttttg ctctcgtacg tttgatgcaa atgatttgta tcaggggcag aattttaaca
181 aggtcctcag ttccttagtg actctaaata aagtaacagc agacatcggg ctggggagtg
241 actccgtgtg tgcccggccc tcgtctcacc gcataaagtc ttttgactcc cttggatcac
301 agtctttgca cactcggact tcaaaactgt tccagggcca gtatcggagt ttggacatga
361 ccgataatag caacaatcaa ctggtagtaa gagcaaagtt taacttccag cagaccaatg
421 aggacgagct ttccttctca aaaggagacg tcatccatgt cacccgtgtg gaagagggag
481 gctggtggga gggcacactc aacggccgga ccggctggtt ccccagcaac tacgtgcgcg
541 aggtcaaggc cagcgagaag cctgtgtctc ccaaatcagg aacactgaag agccctccca
601 aaggatttga tacgactgcc ataaacaaaa gctattacaa tgtggtgcta cagaatattt
661 tagaaacaga aaatgaatat tctaaagaac ttcagactgt gctttcaacg tacctacggc
721 cattgcagac cagtgagaag ttaagttcag caaacatttc atatttaatg ggaaatctag
781 aagaaatatg ttctttccag caaatgctcg tacagtcttt agaagaatgc accaagttgc
841 ccgaagctca gcagagagtc ggaggctgct ttttaaacct gatgccacag atgaaaaccc
901 tgtacctcac gtattgtgcc aatcaccctt ctgcagtgaa tgtcctcacg gaacacagtg
961 aggagttggg ggagttcatg gagaccaaag gtgccagcag ccctgggatt ctcgtgctga
1021 ccacgggcct gagcaaaccc ttcatgcgcc tggataaata ccctacgctg ctcaaagagc
1081 tcgagagaca catggaggat tatcatacag atagacaaga tattcaaaaa tccatggctg
1141 ccttcaaaaa cctttcagcc caatgtcaag aagtccggaa gaggaaagag cttgagctgc
1201 agatcctgac ggaagccatc cggaactggg agggcgatga cattaaaact ctgggcaacg
1261 tcacttacat gtcccaggtc ctgattcagt gtgccggaag tgaggaaaag aatgaaagat
1321 atcttctact cttcccaaat gttttgctaa tgttgtctgc cagtcctagg atgagtggct
1381 ttatctatca gggaaagctt ccaacgacag gaatgacaat cacaaagctt gaggacagtg
1441 aaaatcatag aaatgcattt gaaatatcag ggagcatgat tgagcggata ttagtgtcgt
1501 gcaacaacca gcaggatctg caggaatggg tggagcacct acagaagcaa acgaaggtca
1561 cgtctgtggg aaaccccacc ataaagcctc attcagtgcc atctcatacc ctcccctccc
1621 acccggtcac tccgtccagc aagcacgcag acagcaagcc cgcgccgctg acgcccgcct
1681 accacacgct gccccacccc tcccaccacg gcaccccgca caccaccacc aactggggac
1741 ccctggagcc tccgaaaaca cccaagccct ggagcctgag ctgcctgcgg cccgcgcctc
1801 ccctccggcc ctcagctgct ctctgctaca aggaggatct tagtaagagc cctaagacca
1861 tgaaaaagct gctgcccaag cgcaaacctg aacggaagcc ttcagatgag gagttcgcgt
1921 cccggaaaag cacagctgct ttggaagaag atgctcagat tctgaaagtc attgaagctt
1981 actgcaccag cgccaaaaca aggcaaacac tcaattcaag ttcacgcaaa gaatctgctc
2041 cacaagtttt gcttccagaa gaagagaaaa ttatagtgga agaaactaaa agtaatggtc
2101 agacagtgat agaagaaaag agtcttgtgg ataccgtata tgcattaaag gatgaagttc
2161 aagaattaag acaggacaac aaaaagatga agaaatctct agaggaagaa cagagagccc
2221 gcaaagacct ggagaagctg gtgaggaaag tcctgaagaa catgaatgat cctgcctggg
2281 atgagaccaa tctataaggg acgtcctcag ttctttctgt tgaagaccag ttctgaggtg
2341 aagctgggca cccctgaccc aagtcggggt gcactcagga ccacagggca gggctgggtg
2401 gggcgccacc ttgctctctg tatatagaaa agctggagct tattctgcga atggagacga
2461 tcaaaccatg actgatgaat ccagacagga gggattgact ctgaggacct gagctacatc
2521 aatccactct gtgaacatct cagttacctc attctgcaat aagttcagtg actgactaaa
2581 agtcttgttt ttccagactt tgaattgaat atataaatat tatatataca tgtttcttgt
2641 aaatatccca ttttgaatgc atacctgtgg tggttctgtc cgggctaatc cccatgctag
2701 aatgtccttt ccagctacgt gaataagaag tcccatgccc gcacccaccg gaagcagaag
2761 cctggtggat gcctggttcg ttccgcagca ccagggcctc caccgtgctg tggcagcacc
2821 ccccatgtcg gtatttctaa ataaccttat ttatacctgc agagatacac ttcagtccca
2881 ttcagaagtc ttctcttaaa gcagcattac agtcccagac ctgcgggttt ctgagggcaa
2941 cttgctggct gacagactca gtcttgacct caaggaaggc ccatacggca ctgccgcatc
3001 cacctagagg tgtttgctct tgtccgctgt ctgagtactg tgattctcag atgagtttgc
3061 tgcgttttgg gaggacacag acggttctgt ataggctagt tcagtaacaa caaaatacac
3121 tgttttgtct tccctcaaag agagatctta ctagaacctg taaatagaat gtattattta
3181 ttataagtca ctgcagctga tgaaaacaga tggaggccat gctgcaggct gatactgatg
3241 ggtggagttt tgtcatcagg ccagcctcat cccgaggtct cctccaccat tggccgtagc
3301 cagcaggctt cagtgctcac cgaaagtaaa atcccctcct tcagcaagaa taaagcaata
3361 tacaccttag gttccactaa gtaacatagg cataagcagg gaacgtttcc cccactgtgt
3421 tccagtgcag aggagacgaa gcctgtcctc accgcggctc gctgggccca ggctggctct
3481 ggaaagcctg tgcggtcctg ggcaggaagc ccggcccgtg gagcaggttt tcgttctgct
3541 tcagcaataa ataagggtga ccacagggac tttgcttttg gtttcctttc ctgtgaaaag
3601 gttggtttta aagtgagata cacttttccg tagaacaagt gttctatctt taaaaaccca
3661 aattgcagca ccgtggatta ctggtctcag aacaactcat tgcgcatcag atttgactct
3721 ctgattttct gtctattggc caaattgccc tttaactgca cctgaatcct ttgtgtactg
3781 atgcctttga gctgggcacc ttgggagagt gttgtgttgc tgtttacggt tcttccttgc
3841 ccttgctaat tacagtctct ggtgcccagc aagccccttt ggcttccttc cgtgactggt
3901 cacgttgtct gcctgggctc agcgtggacc tgccccatgc tgcagaacct ggcctcacct
3961 ggacttttca ctagaattgc cagcttcctc aacttagcag atcattcact catgcgggca
4021 caagcaaaga tcaacacttt cttttttggt aagcttgagt tttacaagtt attttttggt
4081 gatgcgtaag acattgcagt gggaaaccat tcaacttgag tttattggag tttgctgttg
4141 tagcaggttt taactcagga acaactcttg tctgatctct ccgcccctct gccgggaggc
4201 gacattaact gtcctctcgg agccggtagc gttgctgtcc gagtccccag gacggatctc
4261 ctgcagacct gccttaatgc tcagatcgaa gtatttcaca agaatacttg tgtttttaac
4321 agcccttccc ctggacggtg cggccatgag ggcctcatgt tacggcattg ccttttcttt
4381 ctgtggatcc agtatcttcc tcggcttttt agggagcagg aaaaatgcgt ctgagagcaa
4441 ctctttttaa aaacctgccc tgttgtatat aactgtgtct gtttcaccgt gtgacctccc
4501 aagggggtgg gaacttgata taaacgttta aaggggccac gatttgcccg agggttactc
4561 ctttgctctc accttgtatg gatgaggaga tgaagccatt tcttatcctg tagatgtgaa
4621 gcactttcag ttttcagcga tgttggaatg tagcatcaga agctcgttcc ttcacactca
4681 gtggcgtctg tgcttgtcca catgcgctgg gcgtctggga ccttgaatgc ctgccctggt
4741 tgtgtggact ccttaatgcc aatcatttct tcacttctct gggacaccca gggcgcctgt
4801 tgacaagtgt ggagaaactc ctaatttaaa tgtcacagac aatgtcctag tgttgactac
4861 tacaatgttg atgctacact gttgtaatta ttaaactgat tatttttctt atgtcaaaaa
4921 aaaaaaaaaa
//