LOCUS BC050370 1883 bp mRNA linear HUM 05-NOV-2003
DEFINITION Homo sapiens ATP-binding cassette, sub-family C (CFTR/MRP), member
3, mRNA (cDNA clone IMAGE:5761266), partial cds.
ACCESSION BC050370
VERSION BC050370.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1883)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1883)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (08-APR-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 98 Row: f Column: 2
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 9955969.
FEATURES Location/Qualifiers
source 1..1883
/db_xref="H-InvDB:HIT000259114"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:5761266"
/tissue_type="Colon, Kidney, Stomach, adult, whole pooled"
/clone_lib="NIH_MGC_116"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene <1..1883
/gene="ABCC3"
/gene_synonym="ABC31"
/gene_synonym="cMOAT2"
/gene_synonym="EST90757"
/gene_synonym="MLP2"
/gene_synonym="MOAT-D"
/gene_synonym="MRP3"
/db_xref="GeneID:8714"
/db_xref="MIM:604323"
CDS <1..1724
/gene="ABCC3"
/gene_synonym="ABC31"
/gene_synonym="cMOAT2"
/gene_synonym="EST90757"
/gene_synonym="MLP2"
/gene_synonym="MOAT-D"
/gene_synonym="MRP3"
/codon_start=3
/product="ABCC3 protein"
/protein_id="AAH50370.1"
/db_xref="GeneID:8714"
/db_xref="MIM:604323"
/translation="PMDALCGSGELGSKFWDSNLSVHTENPDLTPCFQNSLLAWVPCI
YLWVALPCYLLYLRHHCRGYIILSHLSKLKMVLGVLLWCVSWADLFYSFHGLVHGRAP
APVFFVTPLVVGVTMLLATLLIQYERLQGVQSSGVLIIFWFLCVVCAIVPFRSKILLA
KAEGEISDPFRFTTFYIHFALVLSALILACFREKPPFFSAKNVDPNPYPETSAGFLSR
LFFWWFTKMAIYGYRHPLEEKDLWSLKEEDRSQMVVQQLLEAWRKQEKQTARHKASAA
PGKNASGEDEVLLGARPRPRKPSFLKALLATFGSSFLISACFKLIQDLLSFINPQLLS
ILIRFISNPMAPSWWGFLVAGLMFLCSMMQSLILQHYYHYIFVTGVKFRTGIMGVIYR
KALVITNSVKRASTVGEIVNLMSVDAQRFMDLAPFLNLLWSAPLQIILAIYFLWQNLG
PSVLAGVAFMVLLIPLNGAVAVKMRAFQVKQMKLKDSRIKLMSEILNGIKVLKLYAWE
PSFLKQVEGIRQGELQLLRTAAYLHTTTTFTWMCSPFLVRLGTGLGPCLHGSGCPGMA
RAHWTLP"
misc_feature 936..1562
/gene="ABCC3"
/gene_synonym="ABC31"
/gene_synonym="cMOAT2"
/gene_synonym="EST90757"
/gene_synonym="MLP2"
/gene_synonym="MOAT-D"
/gene_synonym="MRP3"
/note="ABC_membrane; Region: ABC transporter transmembrane
region. This family represents a unit of six transmembrane
helices. Many members of the ABC transporter family
(pfam00005) have two such regions"
/db_xref="CDD:pfam00664"
BASE COUNT 395 a 581 c 477 g 430 t
ORIGIN
1 gccccatgga cgccctgtgc ggttccgggg agctcggctc caagttctgg gactccaacc
61 tgtctgtgca cacagaaaac ccggacctca ctccctgctt ccagaactcc ctgctggcct
121 gggtgccctg catctacctg tgggtcgccc tgccctgcta cttgctctac ctgcggcacc
181 attgtcgtgg ctacatcatc ctctcccacc tgtccaagct caagatggtc ctgggtgtcc
241 tgctgtggtg cgtctcctgg gcggaccttt tttactcctt ccatggcctg gtccatggcc
301 gggcccctgc ccctgttttc tttgtcaccc ccttggtggt gggggtcacc atgctgctgg
361 ccaccctgct gatacagtat gagcggctgc agggcgtaca gtcttcgggg gtcctcatta
421 tcttctggtt cctgtgtgtg gtctgcgcca tcgtcccatt ccgctccaag atccttttag
481 ccaaggcaga gggtgagatc tcagacccct tccgcttcac caccttctac atccactttg
541 ccctggtact ctctgccctc atcttggcct gcttcaggga gaaacctcca tttttctccg
601 caaagaatgt cgaccctaac ccctaccctg agaccagcgc tggctttctc tcccgcctgt
661 ttttctggtg gttcacaaag atggccatct atggctaccg gcatcccctg gaggagaagg
721 acctctggtc cctaaaggaa gaggacagat cccagatggt ggtgcagcag ctgctggagg
781 catggaggaa gcaggaaaag cagacggcac gacacaaggc ttcagcagca cctgggaaaa
841 atgcctccgg cgaggacgag gtgctgctgg gtgcccggcc caggccccgg aagccctcct
901 tcctgaaggc cctgctggcc accttcggct ccagcttcct catcagtgcc tgcttcaagc
961 ttatccagga cctgctctcc ttcatcaatc cacagctgct cagcatcctg atcaggttta
1021 tctccaaccc catggccccc tcctggtggg gcttcctggt ggctgggctg atgttcctgt
1081 gctccatgat gcagtcgctg atcttacaac actattacca ctacatcttt gtgactgggg
1141 tgaagtttcg tactgggatc atgggtgtca tctacaggaa ggctctggtt atcaccaact
1201 cagtcaaacg tgcgtccact gtgggggaaa ttgtcaacct catgtcagtg gatgcccagc
1261 gcttcatgga ccttgccccc ttcctcaatc tgctgtggtc agcacccctg cagatcatcc
1321 tggcgatcta cttcctctgg cagaacctag gtccctctgt cctggctgga gtcgctttca
1381 tggtcttgct gattccactc aacggagctg tggccgtgaa gatgcgcgcc ttccaggtaa
1441 agcaaatgaa attgaaggac tcgcgcatca agctgatgag tgagatcctg aacggcatca
1501 aggtgctgaa gctgtacgcc tgggagccca gcttcctgaa gcaggtggag ggcatcaggc
1561 agggtgagct ccagctgctg cgcacggcgg cctacctcca caccacaacc accttcacct
1621 ggatgtgcag ccccttcctg gtgaggcttg gcacagggct gggtccctgc ctccatggct
1681 ctgggtgccc aggcatggcc agggctcatt ggactctacc ctgacaccac ctccacgctg
1741 ctcaggtgac cctgatcacc ctctgggtgt acgtgtacgt ggacccaaac aatgtgctgg
1801 acgccgagaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
1861 aaaaaaaaaa aaaaaaaaaa aaa
//