LOCUS BC050050 2536 bp mRNA linear HUM 28-JUL-2005
DEFINITION Homo sapiens mitogen-activated protein kinase kinase kinase 12,
mRNA (cDNA clone MGC:42552 IMAGE:4824512), complete cds.
ACCESSION BC050050
VERSION BC050050.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2536)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2536)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (01-APR-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Miklos Palkovits, M.D., Ph.D.
cDNA Library Preparation: Michael J. Brownstein (NHGRI) & Shiraki
Toshiyuki and Piero Carninci (RIKEN)
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 71 Row: k Column: 3.
FEATURES Location/Qualifiers
source 1..2536
/db_xref="H-InvDB:HIT000053387"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:42552 IMAGE:4824512"
/tissue_type="Testis"
/clone_lib="NIH_MGC_97"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..2536
/gene="MAP3K12"
/gene_synonym="DLK"
/gene_synonym="MUK"
/gene_synonym="ZPKP1"
/db_xref="GeneID:7786"
/db_xref="MIM:600447"
CDS 273..1976
/gene="MAP3K12"
/gene_synonym="DLK"
/gene_synonym="MUK"
/gene_synonym="ZPKP1"
/codon_start=1
/product="MAP3K12 protein"
/protein_id="AAH50050.1"
/db_xref="GeneID:7786"
/db_xref="MIM:600447"
/translation="MACLHETRTPSPSFGGFVSTLSEASMRKLDPDTSDCTPEKDLTP
TQCVLRDVVPLGGQGGGGPSPSPGGEPPPEPFANSVLQLHEQDAGGPGGAAGSPESRA
SRVRADEVRLQCQSGSGFLEGLFGCLRPVWTMIGKAYSTEHKQQQEDLWEVPFEEILD
LQWVGSGAQGAVFLGRFHGEEVAVKKVRDLKETDIKHLRKLKHPNIITFKGVCTQAPC
YCILMEFCAQGQLYEVLRAGRPVTPSLLVDWSMGIAGGMNYLHLHKIIHRDLKSPNML
ITYDDVVKISDFGTSKELSDKSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLW
ELLTGEIPYKDVDSSAIIWGVGSNSLHLPVPSSCPDGFKILLRQCWNSKPRNRPSFRQ
ILLHLDIASADVLSTPQETYFKSQAEWREEVKLHFEKIKSEGTCLHRLEEELVMRRRE
ELRHALDIREHYERKLERANNLYMELNALMLQLELKERELLRREQALERRCPGLLKPH
PSRGPQLPSLHESHSYSLYIEKYLYKLYIYTYIYIYAPHNQQKDGAVPAVSQARGRLI
P"
BASE COUNT 594 a 668 c 747 g 527 t
ORIGIN
1 tgttcaagcc gagcagggac ggggctaggg gtcggggggt gggggcagaa agctgaagct
61 gacacccgtg catccggaca ccgcacgagc atcgcctgtg acagcgcccc gggtccggtg
121 gagggcagcg gggggaggag ggaaggagga ggagaaggag gaggaggcgg gagcagcatc
181 cggagcggag ctgcagcagc gccgcctttt gtgctgcggc cgcggagccc ccgagggccc
241 agtgttcacc atcataccag gggccagagg cgatggcttg cctccatgag acccgaacac
301 cctctccttc ctttgggggc tttgtgtcta ccctaagtga ggcatccatg cgcaagctgg
361 acccagacac ttctgactgc actcccgaga aggacctgac gcctacccag tgtgtacttc
421 gagatgtggt accccttggt gggcagggtg ggggagggcc cagcccctcc ccaggtggag
481 agccgccccc tgagcctttt gccaacagtg tcctgcagct acatgagcag gatgcagggg
541 gcccaggggg agcagctggg tcacctgaga gtcgggcatc cagagttcga gctgacgagg
601 tgcgactgca gtgccagagt ggcagtggct tccttgaggg cctctttggc tgcctgcgcc
661 ctgtctggac catgattggc aaagcctact ccactgagca caagcagcag caggaagacc
721 tttgggaggt cccctttgag gaaatcctgg acctgcagtg ggtgggctca ggggcccagg
781 gtgctgtctt cctggggcgc ttccacgggg aggaggtggc tgtgaagaag gtgcgagacc
841 tcaaagaaac cgacatcaag cacttgcgaa agctgaagca ccccaacatc atcactttca
901 agggtgtgtg cacccaggct ccctgctact gcatcctcat ggagttctgc gcccagggcc
961 agctgtatga ggtactgcgg gctggccgcc ctgtcacccc ctccttactg gttgactggt
1021 ccatgggcat cgctggtggc atgaactacc tgcacctgca caagattatc cacagggatc
1081 tcaagtcacc caacatgcta atcacctacg acgatgtggt gaagatctca gattttggca
1141 cttccaagga gctgagtgac aagagcacca agatgtcctt tgcagggaca gtagcctgga
1201 tggcccctga ggtgatccgc aatgaacctg tgtctgagaa ggtcgacatc tggtcctttg
1261 gcgtggtgct atgggaactg ctgactggtg agatccccta caaagacgta gattcctcag
1321 ccattatctg gggtgtggga agcaacagtc tccatctgcc cgtgccctcc agttgcccag
1381 atggtttcaa gatcctgctt cgccagtgct ggaatagcaa accacgaaat cgcccatcat
1441 tccgacagat cctgctgcat ctggacattg cctcagctga tgtactctcc acaccccagg
1501 agacttactt taagtcccag gcagagtggc gggaagaagt aaaactgcac tttgaaaaga
1561 ttaagtcaga agggacctgt ctgcaccgcc tagaagagga actggtgatg aggaggaggg
1621 aggagctcag acacgccctg gacatcaggg agcactatga aaggaagctg gagagagcca
1681 acaacctgta tatggaactt aatgccctca tgttgcagct ggaactcaag gagagggagc
1741 tgctcaggcg agagcaagct ttagagcgga ggtgcccagg cctgctgaag ccacaccctt
1801 cccggggccc ccagcttccc tccctccatg aaagccactc gtattccttg tacatagaga
1861 aatatttata taaattatat atatatacat atatatatat atatgcgcca cataatcaac
1921 agaaagatgg ggctgtccca gccgtaagtc aggctcgagg gagactgatc ccctgaccaa
1981 ttcacctgat aaactctagg gacactggca gctgtggaaa tgaatgaggc acagccgtag
2041 agctgtggct aagggcaagc cccttcctgc cccaccccat tccttatatt cagcaagcaa
2101 caaggcaata gaaaagccag ggttgtcttt atattcttta tccccaaata atagggggtg
2161 gggggagggg cggtgggagg ggcaggagag aaaaccactt agactgcact tttctgttcc
2221 gtttactctg tttacacatt ttgcacttgg gaggagggag gctaaggctg ggtcctcccc
2281 tctgaggttt ctcaggtggc aatgtaactc atttttttgt cccaccattt atcttctctg
2341 cccaagccct gtcttaaggc ccagggggag gttaggagac tgatagcatg tgatggctca
2401 ggctgaagaa ccggggtgct gtttaagtcc ctgcttttat cctggtgcct gattggggtg
2461 gggactgtcc tactgtaacc cctgtgaaaa accttgaaat ataacactcc atgcaggctc
2521 aaaaaaaaaa aaaaaa
//