LOCUS BC049215 3010 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens 2'-5'-oligoadenylate synthetase 2, 69/71kDa, mRNA
(cDNA clone MGC:51939 IMAGE:5517804), complete cds.
ACCESSION BC049215
VERSION BC049215.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3010)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3010)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (21-MAR-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 93 Row: n Column: 8
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 4505484.
FEATURES Location/Qualifiers
source 1..3010
/db_xref="H-InvDB:HIT000053365"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:51939 IMAGE:5517804"
/tissue_type="Uterus, leiomyosarcoma"
/clone_lib="NIH_MGC_71"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..3010
/gene="OAS2"
/db_xref="GeneID:4939"
/db_xref="HGNC:HGNC:8087"
/db_xref="MIM:603350"
CDS 42..2105
/gene="OAS2"
/codon_start=1
/product="2'-5'-oligoadenylate synthetase 2, 69/71kDa"
/protein_id="AAH49215.1"
/db_xref="GeneID:4939"
/db_xref="HGNC:HGNC:8087"
/db_xref="MIM:603350"
/translation="MGNGESQLSSVPAQKLGWFIQEYLKPYEECQTLIDEMVNTICDV
LQEPEQFPLVQGVAIGGSYGRKTVLRGNSDGTLVLFFSDLKQFQDQKRSQRDILDKTG
DKLKFCLFTKWLKNNFEIQKSLDGFTIQVFTKNQRISFEVLAAFNALSLNDNPSPWIY
RELKRSLDKTNASPGEFAVCFTELQQKFFDNRPGKLKDLILLIKHWHQQCQKKIKDLP
SLSPYALELLTVYAWEQGCRKDNFDIAEGVRTVLELIKCQEKLCIYWMVNYNFEDETI
RNILLHQLQSARPVILDPVDPTNNVSGDKICWQWLKKEAQTWLTSPNLDNELPAPSWN
VLPAPLFTTPGHLLDKFIKEFLQPNKCFLEQIDSAVNIIRTFLKENCFRQSTAKIQIV
RGGSTAKGTALKTGSDADLVVFHNSLKSYTSQKNERHKIVKEIHEQLKAFWREKEEEL
EVSFEPPKWKAPRVLSFSLKSKVLNESVSFDVLPAFNALGQLSSGSTPSPEVYAGLID
LYKSSDLPGGEFSTCFTVLQRNFIRSRPTKLKDLIRLVKHWYKECERKLKPKGSLPPK
YALELLTIYAWEQGSGVPDFDTAEGFRTVLELVTQYQQLCIFWKVNYNFEDETVRKFL
LSQLQKTRPVILDPAEPTGDVGGGDRWCWHLLAKEAKEWLSSPCFKDGTGNPIPPWKV
PVKVI"
BASE COUNT 855 a 749 c 692 g 714 t
ORIGIN
1 atcctaccat tcactgtctt gccggcagcc agctgagagc aatgggaaat ggggagtccc
61 agctgtcctc ggtgcctgct cagaagctgg gttggtttat ccaggaatac ctgaagccct
121 acgaagaatg tcagacactg atcgacgaga tggtgaacac catctgtgac gtcctgcagg
181 aacccgaaca gttccccctg gtgcagggag tggccatagg tggctcctat ggacggaaaa
241 cagtcttaag aggcaactcc gatggtaccc ttgtcctctt cttcagtgac ttaaaacaat
301 tccaggatca gaagagaagc caacgtgaca tcctcgataa aactggggat aagctgaagt
361 tctgtctgtt cacgaagtgg ttgaaaaaca atttcgagat ccagaagtcc cttgatgggt
421 tcaccatcca ggtgttcaca aaaaatcaga gaatctcttt cgaggtgctg gccgccttca
481 acgctctgag cttaaatgat aatcccagcc cctggatcta tcgagagctc aaaagatcct
541 tggataagac aaatgccagt cctggtgagt ttgcagtctg cttcactgaa ctccagcaga
601 agttttttga caaccgtcct ggaaaactaa aggatttgat cctcttgata aagcactggc
661 atcaacagtg ccagaaaaaa atcaaggatt taccctcgct gtctccgtat gccctggagc
721 tgcttacggt gtatgcctgg gaacaggggt gcagaaaaga caactttgac attgctgaag
781 gcgtcagaac cgttctggag ctgatcaaat gccaggagaa gctgtgtatc tattggatgg
841 tcaactacaa ctttgaagat gagaccatca ggaacatcct gctgcaccag ctccaatcag
901 cgaggccagt aatcttggat ccagttgacc caaccaataa tgtgagtgga gataaaatat
961 gctggcaatg gctgaaaaaa gaagctcaaa cctggttgac ttctcccaac ctggataatg
1021 agttacctgc accatcttgg aatgttctgc ctgcaccact cttcacgacc ccaggccacc
1081 ttctggataa gttcatcaag gagtttctcc agcccaacaa atgcttccta gagcagattg
1141 acagtgctgt taacatcatc cgtacattcc ttaaagaaaa ctgcttccga caatcaacag
1201 ccaagatcca gattgtccgg ggaggatcaa ccgccaaagg cacagctctg aagactggct
1261 ctgatgccga tctcgtcgtg ttccataact cacttaaaag ctacacctcc caaaaaaacg
1321 agcggcacaa aatcgtcaag gaaatccatg aacagctgaa agccttttgg agggagaagg
1381 aggaggagct tgaagtcagc tttgagcctc ccaagtggaa ggctcccagg gtgctgagct
1441 tctctctgaa atccaaagtc ctcaacgaaa gtgtcagctt tgatgtgctt cctgccttta
1501 atgcactggg tcagctgagt tctggctcca cacccagccc cgaggtttat gcagggctca
1561 ttgatctgta taaatcctcg gacctcccgg gaggagagtt ttctacctgt ttcacagtcc
1621 tgcagcgaaa cttcattcgc tcccggccca ccaaactaaa ggatttaatt cgcctggtga
1681 agcactggta caaagagtgt gaaaggaaac tgaagccaaa ggggtctttg cccccaaagt
1741 atgccttgga gctgctcacc atctatgcct gggagcaggg gagtggagtg ccggattttg
1801 acactgcaga aggtttccgg acagtcctgg agctggtcac acaatatcag cagctctgca
1861 tcttctggaa ggtcaattac aactttgaag atgagaccgt gaggaagttt ctactgagcc
1921 agttgcagaa aaccaggcct gtgatcttgg acccagccga acccacaggt gacgtgggtg
1981 gaggggaccg ttggtgttgg catcttctgg caaaagaagc aaaggaatgg ttatcctctc
2041 cctgcttcaa ggatgggact ggaaacccaa taccaccttg gaaagtgccg gtaaaagtca
2101 tctaaaggag gcgttgtctg gaaatagccc tgtaacaggc ttgaatcgaa gaacttctcc
2161 tactgtagca acctgaaatt aactcagaca caaataaagg aaacccagct cacaggagct
2221 taaacagctg gtcagccccc taagccccca ctacaagtga tcctcaggca ggtaacccca
2281 gattcatgca ctgtagggtg ctgcgcagca tccctagtct ctacccagta gatgccacta
2341 gccctcctct cccagtgaca accaaaagtc ttcagacatt gtcaaacgtt cccctgggtt
2401 cacagatctt tctgcctttg gcttttggct ccaccctctt tagctgttaa tttgagtact
2461 tatggccctg aaagcggcca cggtgcctcc agatggcagg tttgcaatcc aagcaggaag
2521 aaggaaaaga tacccaaagg tcaagaacac agtgatttta ttagaagttt catccgcaaa
2581 ttttcttcca tttcattgct cagaaatgtc atgtggctac ctgtaacttg aaggtggcta
2641 caaagatgac tgtggacgtg ggttgcactg gccacccaag gatgtctgcc acacctctcc
2701 aaagccctcc ctacctacca agatatacct gatatattcc accaggatat cctccctcca
2761 gatatacttg gttctctcca ccaggttctt tctttaaagc aggatttctc aactttgata
2821 cttactcaca tttggggcta gacagttctt tgtttggagg ctctcttgtg cattgtagga
2881 tgttgagcag catctctggc ctgtacccag tagatgccac ccagttgtga caattaaaag
2941 tgtcttgaga ctttaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
3001 aaaaaaaaaa
//