LOCUS BC049206 2926 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens cathepsin O, mRNA (cDNA clone MGC:51921
IMAGE:5189657), complete cds.
ACCESSION BC049206
VERSION BC049206.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2926)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2926)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (21-MAR-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 93 Row: h Column: 11.
FEATURES Location/Qualifiers
source 1..2926
/db_xref="H-InvDB:HIT000053360"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:51921 IMAGE:5189657"
/tissue_type="Colon, Kidney, Stomach, adult, whole pooled"
/clone_lib="NIH_MGC_116"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2926
/gene="CTSO"
/db_xref="GeneID:1519"
/db_xref="HGNC:HGNC:2542"
/db_xref="MIM:600550"
CDS 3..968
/gene="CTSO"
/codon_start=1
/product="cathepsin O"
/protein_id="AAH49206.1"
/db_xref="GeneID:1519"
/db_xref="HGNC:HGNC:2542"
/db_xref="MIM:600550"
/translation="MDVRALPWLPWLLWLLCRGGGDADSRAPFTPTWPRSREREAAAF
RESLNRHRYLNSLFPSENSTAFYGINQFSYLFPEEFKAIYLRSKPSKFPRYSAEVHMS
IPNVSLPLRFDWRDKQVVTQVRNQQMCGGCWAFSVVGAVESAYAIKGKPLEDLSVQQV
IDCSYNNYGCNGGSTLNALNWLNKMQVKLVKDSEYPFKAQNGLCHYFSGSHSGFSIKG
YSAYDFSDQEDEMAKALLTFGPLVVIVDAVSWQDYLGGIIQHHCSSGEANHAVLITGF
DKTGSTPYWIVRNSWGSSWGVDGYAHVKMGSNVCGIADSVSSIFV"
BASE COUNT 874 a 574 c 561 g 917 t
ORIGIN
1 caatggacgt gcgggcgctg ccgtggctgc cgtggctgct gtggctgctg tgccggggcg
61 gcggcgatgc ggactcccgc gcccccttca ccccgacctg gccgcggagc cgcgagcgtg
121 aagccgccgc cttccgggaa agtcttaata gacatcgata cttgaattct ttatttccca
181 gtgaaaactc caccgccttc tatggaataa atcagttttc ctatttgttt cctgaagagt
241 ttaaagccat ttatttaaga agcaaacctt ccaagtttcc cagatactca gcagaagtac
301 atatgtccat ccccaatgtg tctttgccgt taagatttga ctggagggac aagcaggttg
361 tgacacaagt gagaaaccag cagatgtgtg gaggatgctg ggccttcagc gtggtggggg
421 cagtggaatc tgcttatgca ataaagggga agcccctgga agacctaagt gtccagcagg
481 tcattgactg ttcgtataat aattatggct gcaatggagg ctctactctc aatgctttga
541 actggttaaa caagatgcaa gtaaaactgg tgaaagattc agaatatcct tttaaagcac
601 aaaatggtct gtgccattac ttttctggtt cacattctgg attttcaatc aaaggttatt
661 ctgcatatga cttcagtgac caagaagatg aaatggcaaa agcacttctt acctttggcc
721 ctttggtagt catagtagat gcagtgagct ggcaagatta tctgggaggc attatacagc
781 atcactgctc tagtggagaa gcaaatcatg cagttctcat aactgggttt gataaaacag
841 gaagcactcc atattggatt gtgcggaatt cctggggaag ttcttgggga gtagatggtt
901 atgcccatgt caaaatggga agtaatgttt gtggtattgc agattccgtt tcttctatat
961 ttgtgtgaca tgttgggcag atcaagagac agctacaaaa atgaaggttt tcataatgca
1021 atgtaacata gtacttcaaa gtattattca acttcaagtt tcagcaacta cctacaaaag
1081 attctaaggc ctagtagtat ttaaactaag tttcagaatg ttcccttctt gtagagagat
1141 ggacaaccaa agtcagtggg acaaactcca gcacagaagc ctgcgaggaa gcctatggaa
1201 tagtttcctg tcctgagacg aaattcagat taggagatat tttaggcccc tgcaactggg
1261 gaaggctact gtttgttttt gtttgcttat tatttatttg tttgtttatt gtgagatatt
1321 tcaggtggga tcaaagaggt cataagaatt tattttcttt tgtggggtgt aactactagc
1381 tttagattac ccctatacac aagaatggcc aacctaaaat tatgtgtgtc ttgtacagtt
1441 agttatatta gcagccctct gagatggcgt atctatcgga aggatttcaa acaccaattg
1501 ctttacctga acaaatggtg cttacccttt gaacagcaga gtgaccacgt agaaggaagg
1561 aaaagggcaa aatcgcttca gttaaactga aattaaatga acaataaggc aactatataa
1621 gtaacttcta gtagcattgc ctgagagaca aattattgtt tgataatttt cattgtgaat
1681 aggaatccaa tagatcatat tgcttacttt gttcttttta tactatagaa taatattttg
1741 ttctctagta tatcaaaata ccaaaatatt atctcatatt ttctccctct ttctcttact
1801 cttaccaagt tttcctggtg gcttggcttc cctgactaaa gaattaagtc tcatttttac
1861 tttccatttc tattttctta ccacttggtt ggctcccttt gtctctgtac ctttaccaac
1921 attaggatct cacctctttc ttcctccctt aattcataag caccactcct atcaaagtcc
1981 catctcttaa ccctgggtat caaacaaact gtgagttttc cagaatctgt ttcccagttt
2041 tcccctcagc tttcctggtc tcccatctga actgcttctt tgtgcacctc ttgttctttc
2101 tcttggctcc cagtcttgat tcctgtgatc actcttgcat cactaattgc acaagtgatt
2161 tcaggtgcaa ttctgattag cctgcgtcca cacagtgatc gatgatccta tgtgcctaga
2221 aaggacactg tgtgctgctc atgacctgca acaggaaaaa agccacttct tgttagcagt
2281 gtaagaacct tagagcaaag gagttgacct tctgattgaa tataagcaca accatattaa
2341 atgaatcaat acaagaaaat tatttctgat actatgtatg tacatatttc ttctctaaaa
2401 tgtatcattc ttttctaatg tatatgatct aacaaaaatg aaacatgaaa tgcagtagca
2461 accactaaaa aaaaaaattc aaggacatct aactttttct ctcacttttg ccctttgttt
2521 atccttccct gtgattagat aaacaaaata aaaaacaaaa tgctgtattt ctcttcttac
2581 gccagtcaga accaatccga aaagaatgtg tgttgactca ggtttggagt tatttcagga
2641 agacagatat tgacctttta attgataaat attcttatta tcctggaatg ccagaaaaga
2701 actatgtcct gcttgtctag tttgtattcg ctgactttct atgtgatata gatgcatttg
2761 taatactctt tttcaagtgc taaaggattt ctaaaatttc aaactgatta atatgtttct
2821 gctgttctgg attttgatga catttacaat aaaacaacct acatttgaaa aaaaaaaaaa
2881 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaa
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