LOCUS BC048768 6412 bp mRNA linear HUM 30-JUN-2006
DEFINITION Homo sapiens protein tyrosine phosphatase, receptor type, F, mRNA
(cDNA clone MGC:47527 IMAGE:5502598), complete cds.
ACCESSION BC048768
VERSION BC048768.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 6412)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 6412)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (14-MAR-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 82 Row: f Column: 2.
FEATURES Location/Qualifiers
source 1..6412
/db_xref="H-InvDB:HIT000053334"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:47527 IMAGE:5502598"
/tissue_type="Eye, retinoblastoma"
/clone_lib="NIH_MGC_67"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..6412
/gene="PTPRF"
/db_xref="GeneID:5792"
/db_xref="HGNC:HGNC:9670"
/db_xref="MIM:179590"
CDS 327..6023
/gene="PTPRF"
/codon_start=1
/product="protein tyrosine phosphatase, receptor type, F"
/protein_id="AAH48768.1"
/db_xref="GeneID:5792"
/db_xref="HGNC:HGNC:9670"
/db_xref="MIM:179590"
/translation="MAPEPAPGRTMVPLVPALVMLGLVAGAHGDSKPVFIKVPEDQTG
LSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDE
AIYECTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATMLCAAGG
NPDPEISWFKDFLPVDPATSNGRIKQLRSGALQIESSEESDQGKYECVATNSAGTRYS
APANLYVRVRRVAPRFSIPPSSQEVMPGGSVNLTCVAVGAPMPYVKWMMGAEELTKED
EMPVGRNVLELSNVVRSANYTCVAISSLGMIEATAQVTVKALPKPPIDLVVTETTATS
VTLTWDSGNSEPVTYYGIQYRAAGTEGPFQEVDGVATTRYSIGGLSPFSEYAFRVLAV
NSIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSASTMLVQWEPPEEPNGLVRGYRVY
YTPDSRRPPNAWHKHNTDAGLLTTVGSLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQ
QGVPAQPADFQAEVESDTRIQLSWLLPPQERIIMYELVYWAAEDEDQQHKVTFDPTSS
YTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTVR
VSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEKWTEYRV
WVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQ
IRGYQVTYVRLENGEPRGLPIIQDVMLAEAQETTISGLTPETTYSVTVAAYTTKGDGA
RSKPKIVTTTGAVPGRPTMMISTTAMNTALLQWHPPKELPGELLGYRLQYCRADEARP
NTIDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFEKEIRTPEDLPSGFPQNLH
VTGLTTSTTELAWDPPVLAERNGRIISYTVVFRDINSQQELQNITTDTRFTLTGLKPD
TTYDIKVRAWTSKGSGPLSPSIQSRTMPVEQVFAKNFRVAAAMKTSVLLSWEVPDSYK
SAVPFKILYNGQSVEVDGHSMRKLIADLQPNTEYSFVLMNRGSSAGGLQHLVSIRTAP
DLLPHKPLPASAYIEDGRFDLSMPHVQDPSLVRWFYIVVVPIDRVGGSMLTPRWSTPE
ELELDELLEAIEQGGEEQRRRRRQAERLKPYVAAQLDVLPETFTLGDKKNYRGFYNRP
LSPDLSYQCFVLASLKEPMDQKRYASSPYSDEIVVQVTPAQQQEEPEMLWVTGPVLAV
ILIILIVIAILLFKRKRTHSPSSKDEQSIGLKDSLLAHSSDPVEMRRLNYQTPGMRDH
PPIPITDLADNIERLKANDGLKFSQEYESIDPGQQFTWENSNLEVNKPKNRYANVIAY
DHSRVILTSIDGVPGSDYINANYIDGYRKQNAYTATQGPLPETMGDFWRMVWEQRTAT
VVMMTRLEEKSRVKCDQYWPARGTETCGLIQVTLLDTVELATYTVRTFALHKSGSSEK
RELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVI
DAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAATCGHTEVPARN
LYAHIQKLGQVPPGESVTAMELEFKLLASSKAHTSRFISANLPCNKFKNRLVNIMPYE
LTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTII
VMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSR
TIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFIT
LSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYAT"
BASE COUNT 1356 a 1984 c 1942 g 1130 t
ORIGIN
1 gcggtggcgg cggcagaggc ggcggctcca gcttcggctc cggctcgggc tcgggctccg
61 gctccggctc cggctccggc tccagctcgg gtggcggtgg cgggagcggg accaggtgga
121 ggcggcggcg gcagaggagt gggagcagcg gccctagcgg cttgcggggg gacatgcgga
181 ccgacggccc ctggataggc ggaaggagtg gaggccctgg tgcccggccc ttggtgctga
241 gtatccagca agagtgaccg gggtgaagaa gcaaagactc ggttgattgt cctgggctgt
301 ggctggctgt ggagctagag ccctggatgg cccctgagcc agccccaggg aggacgatgg
361 tgccccttgt gcctgcactg gtgatgcttg gtttggtggc aggcgcccat ggtgacagca
421 aacctgtctt cattaaagtc cctgaggacc agactgggct gtcaggaggg gtagcctcct
481 tcgtgtgcca agctacagga gaacccaagc cgcgcatcac atggatgaag aaggggaaga
541 aagtcagctc ccagcgcttc gaggtcattg agtttgatga tggggcaggg tcagtgcttc
601 ggatccagcc attgcgggtg cagcgagatg aagccatcta tgagtgtaca gctactaaca
661 gcctgggtga gatcaacact agtgccaagc tctcagtgct cgaagaggaa cagctgcccc
721 ctgggttccc ttccatcgac atggggcctc agctgaaggt ggtggagaag gcacgcacag
781 ccaccatgct atgtgccgca ggcggaaatc cagaccctga gatttcttgg ttcaaggact
841 tccttcctgt agaccctgcc acgagcaacg gccgcatcaa gcagctgcgt tcaggtgcct
901 tgcagataga gagcagtgag gaatccgacc aaggcaagta cgagtgtgtg gcgaccaact
961 cggcaggcac acgttactca gcccctgcga acctgtatgt gcgagtgcgc cgcgtggctc
1021 ctcgtttctc catccctccc agcagccagg aggtgatgcc aggcggcagc gtgaacctga
1081 catgcgtggc agtgggtgca cccatgccct acgtgaagtg gatgatgggg gccgaggagc
1141 tcaccaagga ggatgagatg ccagttggcc gcaacgtcct ggagctcagc aatgtcgtac
1201 gctctgccaa ctacacctgt gtggccatct cctcgctggg catgatcgag gccacagccc
1261 aggtcacagt gaaagctctt ccaaagcctc cgattgatct tgtggtgaca gagacaactg
1321 ccaccagtgt caccctcacc tgggactctg ggaactcgga gcctgtaacc tactatggca
1381 tccagtaccg cgcagcgggc acggagggcc cctttcagga ggtggatggt gtggccacca
1441 cccgctacag cattggcggc ctcagccctt tctcggaata tgccttccgc gtgctggcgg
1501 tgaacagcat cgggcgaggg ccgcccagcg aggcagtgcg ggcacgcacg ggagaacagg
1561 cgccctccag cccaccgcgc cgcgtgcagg cacgcatgct gagcgccagc accatgctgg
1621 tgcagtggga gcctcccgag gagcccaacg gcctggtgcg gggataccgc gtctactata
1681 ctccggactc ccgccgcccc ccgaacgcct ggcacaagca caacaccgac gcggggctcc
1741 tcacgaccgt gggcagcctg ctgcctggca tcacctacag cctgcgcgtg cttgccttca
1801 ccgccgtggg cgatggccct cccagcccca ccatccaggt caagacgcag cagggagtgc
1861 ctgcccagcc cgcggacttc caggccgagg tggagtcgga caccaggatc cagctctcgt
1921 ggctgctgcc ccctcaggag cggatcatca tgtatgaact ggtgtactgg gcggcagagg
1981 acgaagacca acagcacaag gtgaccttcg acccaacctc ctcctacaca ctagaggacc
2041 tgaagcctga cacactctac cgcttccagc tggctgcacg ctcggatatg ggggtgggcg
2101 tcttcacccc caccattgag gcccgcacag cccagtccac cccctccgcc cctccccaga
2161 aggtgatgtg tgtgagcatg ggctccacca cggtccgggt aagttgggtc ccgccgcctg
2221 ccgacagccg caacggcgtt atcacccagt actccgtggc ctacgaggcg gtggacggcg
2281 aggaccgcgg gcggcatgtg gtggatggca tcagccgtga gcactccagc tgggacctgg
2341 tgggcctgga gaagtggacg gagtaccggg tgtgggtgcg ggcacacaca gacgtgggcc
2401 ccggccccga gagcagcccg gtgctggtgc gcaccgatga ggacgtgccc agcgggcctc
2461 cgcggaaggt ggaggtggag ccactgaact ccactgctgt gcatgtctac tggaagctgc
2521 ctgtccccag caagcagcat ggccagatcc gcggctacca ggtcacctac gtgcggctgg
2581 agaatggcga gccccgtgga ctccccatca tccaagacgt catgctagcc gaggcccagg
2641 aaaccactat cagcggcctg accccggaga ccacctactc cgttactgtt gctgcctata
2701 ccaccaaggg ggatggtgcc cgcagcaagc ccaaaattgt cactacaaca ggtgcagtcc
2761 caggccggcc caccatgatg atcagcacca cggccatgaa cactgcgctg ctccagtggc
2821 acccacccaa ggaactgcct ggcgagctgc tgggctaccg gctgcagtac tgccgggccg
2881 acgaggcgcg gcccaacacc atagatttcg gcaaggatga ccagcacttc acagtcaccg
2941 gcctgcacaa ggggaccacc tacatcttcc ggcttgctgc caagaaccgg gctggcttgg
3001 gtgaggagtt cgagaaggag atcaggaccc ccgaggacct gcccagcggc ttcccccaaa
3061 acctgcatgt gacaggactg accacgtcta ccacagaact ggcctgggac ccgccagtgc
3121 tggcggagag gaacgggcgc atcatcagct acaccgtggt gttccgagac atcaacagcc
3181 aacaggagct gcagaacatc acgacagaca cccgctttac ccttactggc ctcaagccag
3241 acaccactta cgacatcaag gtccgcgcat ggaccagcaa aggctctggc ccactcagcc
3301 ccagcatcca gtcccggacc atgccggtgg agcaagtgtt tgccaagaac ttccgggtgg
3361 cggctgcaat gaagacgtct gtgctgctca gctgggaggt tcccgactcc tataagtcag
3421 ctgtgccctt taagattctg tacaatgggc agagtgtgga ggtggacggg cactcgatgc
3481 ggaagctgat cgcagacctg cagcccaaca cagagtactc gtttgtgctg atgaaccgtg
3541 gcagcagcgc agggggcctg cagcacctgg tgtccatccg cacagccccc gacctcctgc
3601 ctcacaagcc gctgcctgcc tctgcctaca tagaggacgg ccgcttcgat ctctccatgc
3661 cccatgtgca agacccctcg cttgtcaggt ggttctacat tgttgtggtg cccattgacc
3721 gtgtgggcgg gagcatgctg acgccaaggt ggagcacacc cgaggaactg gagctggacg
3781 agcttctaga agccatcgag caaggcggag aggagcagcg gcggcggcgg cggcaggcag
3841 aacgtctgaa gccatatgtg gctgctcaac tggatgtgct cccggagacc tttaccttgg
3901 gggacaagaa gaactaccgg ggcttctaca accggcccct gtctccggac ttgagctacc
3961 agtgctttgt gcttgcctcc ttgaaggaac ccatggacca gaagcgctat gcctccagcc
4021 cctactcgga tgagatcgtg gtccaggtga caccagccca gcagcaggag gagccggaga
4081 tgctgtgggt gacgggtccc gtgctggcag tcatcctcat catcctcatt gtcatcgcca
4141 tcctcttgtt caaaaggaaa aggacccact ctccgtcctc taaggatgag cagtcgatcg
4201 gactgaagga ctccttgctg gcccactcct ctgaccctgt ggagatgcgg aggctcaact
4261 accagacccc aggtatgcga gaccacccac ccatccccat caccgacctg gcggacaaca
4321 tcgagcgcct caaagccaac gatggcctca agttctccca ggagtatgag tccatcgacc
4381 ctggacagca gttcacgtgg gagaattcaa acctggaggt gaacaagccc aagaaccgct
4441 atgcgaatgt catcgcctac gaccactctc gagtcatcct tacctctatc gatggcgtcc
4501 ccgggagtga ctacatcaat gccaactaca tcgatggcta ccgcaagcag aatgcctaca
4561 ccgccacgca gggccccctg cccgagacca tgggtgattt ctggaggatg gtgtgggaac
4621 agcgcacggc cactgtggtc atgatgacac ggctggagga gaagtcccgg gtaaaatgtg
4681 atcagtactg gccagcccgt ggcaccgaga cctgtggcct tattcaggtg accctgttgg
4741 acacagtgga gctggccaca tacactgtgc gcaccttcgc actccacaag agtggctcca
4801 gtgagaagcg cgagctgcgt cagtttcagt tcatggcctg gccagaccat ggagttcctg
4861 agtacccaac tcccatcctg gccttcctac gacgggtcaa ggcctgcaac cccctagacg
4921 cagggcccat ggtggtgcac tgcagcgcgg gcgtgggccg caccggctgc ttcatcgtga
4981 ttgatgccat gttggagcgg atgaagcacg agaagacggt ggacatctat ggccacgtga
5041 cctgcatgcg atcacagagg aactacatgg tgcagacgga ggaccagtac gtgttcatcc
5101 atgaggcgct gctggaggct gccacgtgcg gccacacaga ggtgcctgcc cgcaacctgt
5161 atgcccacat ccagaagctg ggccaagtgc ctccagggga gagtgtgacc gccatggagc
5221 tcgagttcaa gttgctggcc agctccaagg cccacacgtc ccgcttcatc agcgccaacc
5281 tgccctgcaa caagttcaag aaccggctgg tgaacatcat gccctacgaa ttgacccgtg
5341 tgtgtctgca gcccatccgt ggtgtggagg gctctgacta catcaatgcc agcttcctgg
5401 atggttatag acagcagaag gcctacatag ctacacaggg gcctctggca gagagcaccg
5461 aggacttctg gcgcatgcta tgggagcaca attccaccat catcgtcatg ctgaccaagc
5521 ttcgggagat gggcagggag aaatgccacc agtactggcc agcagagcgc tctgctcgct
5581 accagtactt tgttgttgac ccgatggctg agtacaacat gccccagtat atcctgcgtg
5641 agttcaaggt cacggatgcc cgggatgggc agtcaaggac aatccggcag ttccagttca
5701 cagactggcc agagcagggc gtgcccaaga caggcgaggg attcattgac ttcatcgggc
5761 aggtgcataa gaccaaggag cagtttggac aggatgggcc tatcacggtg cactgcagtg
5821 ctggcgtggg ccgcaccggg gtgttcatca ctctgagcat cgtcctggag cgcatgcgct
5881 acgagggcgt ggtcgacatg tttcagaccg tgaagaccct gcgtacacag cgtcctgcca
5941 tggtgcagac agaggaccag tatcagctgt gctaccgtgc ggccctggag tacctcggca
6001 gctttgacca ctatgcaacg taactaccgc tcccctctcc tccgccaccc ccgccgtggg
6061 gctccggagg ggacccagct cctctgagcc ataccgacca tcgtccagcc ctcctacgca
6121 gatgctgtca ctggcagagc acagcccacg gggatcacag cgtttcagga acgttgccac
6181 accaatcaga gagcctagaa catccctggg caagtggatg gcccagcagg caggcactgt
6241 ggcccttctg tccaccagac ccacctggag cccgcttcaa gctctctgtt gcgctcccgc
6301 atttctcatg cttcttctca tggggtgggg ttggggcaaa gcctcctttt taatacatta
6361 agtggggtag actgaggaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aa
//