LOCUS BC048261 1633 bp mRNA linear HUM 05-NOV-2003
DEFINITION Homo sapiens CDC42 binding protein kinase beta (DMPK-like), mRNA
(cDNA clone IMAGE:5547469), partial cds.
ACCESSION BC048261
VERSION BC048261.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1633)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1633)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (07-MAR-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 93 Row: o Column: 20
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 16357473.
FEATURES Location/Qualifiers
source 1..1633
/db_xref="H-InvDB:HIT000098932"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:5547469"
/tissue_type="Eye, retinoblastoma"
/clone_lib="NIH_MGC_67"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..>1633
/gene="CDC42BPB"
/gene_synonym="KIAA1124"
/gene_synonym="MRCKB"
/db_xref="GeneID:9578"
CDS 158..>1633
/gene="CDC42BPB"
/gene_synonym="KIAA1124"
/gene_synonym="MRCKB"
/codon_start=1
/product="CDC42BPB protein"
/protein_id="AAH48261.1"
/db_xref="GeneID:9578"
/translation="MSAKVRLKKLEQLLLDGPWRNESALSVETLLDVLVCLYTECSHS
ALRRDKYVAEFLEWAKPFTQLVKEMQLHREDFEIIKVIGRGAFGEVAVVKMKNTERIY
AMKILNKWEMLKRAETACFREERDVLVNGDCQWITALHYAFQDENHLYLVMDYYVGGD
LLTLLSKFEDKLPEDMARFYIGEMVLAIDSIHQLHYVHRDIKPDNVLLDVNGHIRLAD
FGSCLKMNDDGTVQSSVAVGTPDYISPEILQAMEDGMGKYGPECDWWSLGVCMYEMLY
GETPFYAESLVETYGKIMNHEERFQFPSHVTDVSEEAKDLIQRLICSRERRLGQNGIE
DFKKHAFFEGLNWENIRNLEAPYIPDVSSPSDTSNFDVDDDVLRNTEILPPGSHTGFS
GLHLPFIGFTFTTESCFSDRGSLKSIMQSNTLTKDEDVQRDLEHSLQMEAYERRIRRL
EQEKLELSRKLQESTQTVQSLHGSSRALSNSNRDKEIKKKKK"
misc_feature 383..1183
/gene="CDC42BPB"
/gene_synonym="KIAA1124"
/gene_synonym="MRCKB"
/note="S_TKc; Region: Serine/Threonine protein kinases,
catalytic domain"
/db_xref="CDD:smart00220"
misc_feature 1187..1366
/gene="CDC42BPB"
/gene_synonym="KIAA1124"
/gene_synonym="MRCKB"
/note="S_TK_X; Region: Extension to Ser/Thr-type protein
kinases"
/db_xref="CDD:smart00133"
BASE COUNT 418 a 393 c 482 g 340 t
ORIGIN
1 gtcggcctag gccggggcgc gacgacgcgg acggggcggc gaggaggcgc cgctgctgcc
61 ggggctcgca gccgccgagc ccccgagggc gcgccctgac ggactggccg agccggcggt
121 gagaggccgg cgcgtcggga gcgggccgcg cggcaccatg tcggccaagg tgcggctcaa
181 gaagctggag cagctgctcc tggacgggcc ctggcgcaac gagagcgccc tgagcgtgga
241 aacgctgctc gacgtgctcg tctgcctgta caccgagtgc agccactcgg ccctgcgccg
301 cgacaagtac gtggccgagt tcctcgagtg ggctaaacca tttacacagc tggtgaaaga
361 aatgcagctt catcgagaag actttgaaat aattaaagta attggaagag gtgcttttgg
421 tgaggttgct gttgtcaaaa tgaagaatac tgaacgaatt tatgcaatga aaatcctcaa
481 caagtgggag atgctgaaaa gagcagagac cgcgtgcttc cgagaggagc gcgatgtgct
541 ggtgaacggc gactgccagt ggatcaccgc gctgcactac gcctttcagg acgagaacca
601 cctgtactta gtcatggatt actatgtggg tggtgattta ctgaccctgc tcagcaaatt
661 tgaagacaag cttccggaag atatggcgag gttctacatt ggtgaaatgg tgctggccat
721 tgactccatc catcagcttc attacgtgca cagagacatt aaacctgaca atgtcctttt
781 ggacgtgaat ggtcatatcc gcctggctga ctttggatca tgtttgaaga tgaatgatga
841 tggcactgtg cagtcctccg tggccgtggg cacacctgac tacatctcgc cggagatcct
901 gcaggcgatg gaggacggca tgggcaaata cgggcctgag tgtgactggt ggtctctggg
961 tgtctgcatg tatgagatgc tctatggaga aacgccgttt tatgcggagt cactcgtgga
1021 gacctatggg aagatcatga accatgaaga gcgattccag ttcccatccc atgtcacgga
1081 tgtatctgaa gaagcgaagg acctcatcca gagactgatc tgcagtagag aacgccggct
1141 ggggcagaat ggaatagagg atttcaaaaa gcatgcgttt tttgaaggtc taaattggga
1201 aaatatacga aacctagaag caccttatat tcctgatgtg agcagtccct ctgacacatc
1261 caacttcgac gtggatgacg acgtgctgag aaacacggaa atattacctc ctggttctca
1321 cacaggcttt tctggattac atttgccatt cattggtttt acattcacaa cggaaagctg
1381 tttttctgat cgaggctctc tgaagagcat aatgcagtcc aacacattaa ccaaagatga
1441 ggatgtgcag cgggacctgg agcacagcct gcagatggaa gcttacgaga ggaggattcg
1501 gaggctggaa caggagaagc tggagctgag caggaagctg caagagtcca cccagaccgt
1561 gcagtccctc cacggctcat ctcgggccct cagcaattca aaccgagata aagaaatcaa
1621 aaaaaaaaaa aaa
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