LOCUS BC048211 2505 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens serum response factor (c-fos serum response
element-binding transcription factor), mRNA (cDNA clone MGC:52246
IMAGE:5808348), complete cds.
ACCESSION BC048211
VERSION BC048211.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2505)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2505)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (07-MAR-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Lou Staudt
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 44 Row: n Column: 4
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 61743976.
FEATURES Location/Qualifiers
source 1..2505
/db_xref="H-InvDB:HIT000053303"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:52246 IMAGE:5808348"
/tissue_type="Lymph, lymphoma"
/clone_lib="NIH_MGC_99"
/lab_host="DH10B"
/note="Vector: pOTB7"
gene 1..2505
/gene="SRF"
/db_xref="GeneID:6722"
/db_xref="HGNC:HGNC:11291"
/db_xref="MIM:600589"
CDS 199..1725
/gene="SRF"
/codon_start=1
/product="serum response factor (c-fos serum response
element-binding transcription factor)"
/protein_id="AAH48211.1"
/db_xref="GeneID:6722"
/db_xref="HGNC:HGNC:11291"
/db_xref="MIM:600589"
/translation="MLPTQAGAAAALGRGSALGGSLNRTPTGRPGGGGGTRGANGGRV
PGNGAGLGPGRLEREAAAAAATTPAPTAGALYSGSEGDSESGEEEELGAERRGLKRSL
SEMEIGMVVGGPEASAAATGGYGPVSGAVSGAKPGKKTRGRVKIKMEFIDNKLRRYTT
FSKRKTGIMKKAYELSTLTGTQVLLLVASETGHVYTFATRKLQPMITSETGKALIQTC
LNSPDSPPRSDPTTDQRMSATGFEETDLTYQVSESDSSGETKDTLKPAFTVTNLPGTT
STIQTAPSTSTTMQVSSGPSFPITNYLAPVSASVSPSAVSSANGTVLKSTGSGPVSSG
GLMQLPTSFTLMPGGAVAQQVPVQAIQVHQAPQQASPSRDSSTDLTQTSSSGTVTLPA
TIMTSSVPTTVGGHMMYPSPHAVMYAPTSGLGDGSLTVLNAFSQAPSTMQVSHSQVQE
PGGVPQVFLTASSGTVQIPVSAVQLHQMAVIGQQAGSSSNLTELQVVNLDTAHSTKSE
"
BASE COUNT 479 a 826 c 770 g 430 t
ORIGIN
1 cgggccacag gggcaggaaa gtgagggccc aggtcggccc gggcgtgcag gggccccggg
61 ttcgcagcgg cggccgcggc agcgatagcg gcactagcag cagcgggagt gccgggttga
121 gccgggaagc cgatggcggc ggctgcggcg gctccgattc ctcgctgact gcccgtccgc
181 cctcctgcat cgagcgccat gttaccgacc caagctgggg ccgcggcggc tctgggccgg
241 ggctcggccc tggggggcag cctgaaccgg accccgacgg ggcggccggg cggcggcggc
301 gggacacgcg gggctaacgg gggccgggtc cccgggaatg gcgcggggct cgggcccggc
361 cgcctggagc gggaggctgc ggcagcggcg gcaaccaccc cggcgcccac cgcgggggcc
421 ctctacagcg gcagcgaggg cgactcggag tcgggcgagg aggaggagct gggcgccgag
481 cggcgcggcc tgaagcggag cctgagcgag atggagatcg gtatggtggt cggtgggccc
541 gaggcgtcgg cagcggccac cgggggctac gggccggtga gcggcgcggt gagcggggcc
601 aagccgggta agaagacccg gggccgcgtg aagatcaaga tggagttcat cgacaacaag
661 ctgcggcgct acacgacctt cagcaagagg aagacgggca tcatgaagaa ggcctatgag
721 ctgtccacgc tgacagggac acaggtgctg ttgctggtgg ccagtgagac aggccatgtg
781 tatacctttg ccacccgaaa actgcagccc atgatcacca gtgagaccgg caaggcactg
841 attcagacct gcctcaactc gccagactct ccaccccgtt cagaccccac aacagaccag
901 agaatgagtg ccactggctt tgaagagaca gatctcacct accaggtgtc ggagtctgac
961 agcagtgggg agaccaagga cacactgaag ccggcgttca cagtcaccaa cctgccgggt
1021 acaacctcca ccatccaaac agcacctagc acctctacca ccatgcaagt cagcagcggc
1081 ccctcctttc ccatcaccaa ctacctggca ccagtgtctg ctagtgtcag ccccagtgct
1141 gtcagcagtg ccaatgggac tgtgctgaag agtacaggta gcggccctgt ctcctctggg
1201 ggccttatgc agctgcctac cagcttcacc ctcatgcctg gtggggcagt ggcccagcag
1261 gtcccagtgc aggccattca agtgcaccag gccccacagc aagcgtctcc ctcccgtgac
1321 agcagcacag acctcacgca gacctcctcc agcgggacag tgacgctgcc cgccaccatc
1381 atgacgtcat ccgtgcccac aactgtgggt ggccacatga tgtaccctag cccgcatgcg
1441 gtgatgtatg cccccacctc gggcctgggt gatggcagcc tcaccgtgct gaatgccttc
1501 tcccaggcac catccaccat gcaggtgtca cacagccagg tccaggagcc aggtggcgtc
1561 ccccaggtgt tcctgacagc atcatctggg acagtgcaga tccctgtttc agcagttcag
1621 ctccaccaga tggctgtgat agggcagcag gccgggagca gcagcaacct caccgagcta
1681 caggtggtga acctggacac cgcccacagc accaagagtg aatgatccgc ccgccgccct
1741 ggacagatgg cccaagggat ggcaccactt atttattgtt gccttttcac gttttcttta
1801 cacacacgtt gacgggccgc aggagggagg cggggaggag gaacgggcag ccacaggact
1861 gagccctctc actccagcca aagaaatggg cctgcctgcc tccacccgtc ctccctcagc
1921 ctccccttct tcccgcccca cctcccattt ctgttgctgg aggggctgtc ctccttcctg
1981 ggaccccctc gccagcttgg ctcgatgttt gccatgagta ttagcttacc caatgggacc
2041 gtgccccacc tccccacaca caggccttct gtggggctgg gcaccgtgtc ctcctctgag
2101 gaagcagttg gggccctctt gccagcctcc ttgctgaccc caggtcagcc ctgtgtctgt
2161 cacaggctgg gtcaaaagag ccctggctct gcccctcagg gggccagctg gggagatggg
2221 ggcttcttcc tcacactgct gtcctctccc ccttcagctc ctgagtagct gggcctgtgc
2281 actgggcagg ttcctggggc cgcctgccct gccttgccgc tccccttgga cctccagggg
2341 ctcctgggtt ggagggaacc accagcgttc ccttctcccc cttgtcttcc cccctctcct
2401 cccagctgct ttacttaaag ttgattttga actttttatt tgaggagacg aagtgaaaac
2461 aaatctataa atatatattt ttaaaataaa aaaaaaaaaa aaaaa
//