LOCUS BC047620 3142 bp mRNA linear HUM 11-AUG-2006
DEFINITION Homo sapiens guanylate cyclase 1, soluble, beta 3, mRNA (cDNA clone
MGC:51012 IMAGE:5264160), complete cds.
ACCESSION BC047620
VERSION BC047620.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3142)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3142)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (03-MAR-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Miklos Palkovits, M.D., Ph.D.
cDNA Library Preparation: Michael J. Brownstein (NHGRI) & Shiraki
Toshiyuki and Piero Carninci (RIKEN)
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 90 Row: o Column: 17
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 4504214.
FEATURES Location/Qualifiers
source 1..3142
/db_xref="H-InvDB:HIT000098703"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:51012 IMAGE:5264160"
/tissue_type="Brain, hippocampus"
/clone_lib="NIH_MGC_95"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..3142
/gene="GUCY1B3"
/gene_synonym="GC-S-beta-1"
/gene_synonym="GC-SB3"
/gene_synonym="GUCB3"
/gene_synonym="GUCSB3"
/db_xref="GeneID:2983"
/db_xref="HGNC:HGNC:4687"
/db_xref="MIM:139397"
CDS 83..1942
/gene="GUCY1B3"
/gene_synonym="GC-S-beta-1"
/gene_synonym="GC-SB3"
/gene_synonym="GUCB3"
/gene_synonym="GUCSB3"
/codon_start=1
/product="guanylate cyclase 1, soluble, beta 3"
/protein_id="AAH47620.2"
/db_xref="GeneID:2983"
/db_xref="HGNC:HGNC:4687"
/db_xref="MIM:139397"
/translation="MYGFVNHALELLVIRNYGPEVWEDIKKEAQLDEEGQFLVRIIYD
DSKTYDLVAAASKVLNLNAGEILQMFGKMFFVFCQESGYDTILRVLGSNVREFLQNLD
ALHDHLATIYPGMRAPSFRCTDAEKGKGLILHYYSEREGLQDIVIGIIKTVAQQIHGT
EIDMKVIQQRNEECDHTQFLIEEKESKEEDFYEDLDRFEENGTQESRISPYTFCKAFP
FHIIFDRDLVVTQCGNAIYRVLPQLQPGNCSLLSVFSLVRPHIDISFHGILSHINTVF
VLRSKEGLLDVEKLECEDELTGTEISCLRLKGQMIYLPEADSILFLCSPSVMNLDDLT
RRGLYLSDIPLHDATRDLVLLGEQFREEYKLTQELEILTDRLQLTLRALEDEKKKTDT
LLYSVLPPSVANELRHKRPVPAKRYDNVTILFSGIVGFNAFCSKHASGEGAMKIVNLL
NDLYTRFDTLTDSRKNPFVYKVETVGDKYMTVSGLPEPCIHHARSICHLALDMMEIAG
QVQVDGESVQITIGIHTGEVVTGVIGQRMPRYCLFGNTVNLTSRTETTGEKGKINVSE
YTYRCLMSPENSDPQFHLEHRGPVSMKGKKEPMQVWFLSRKNTGTEETKQDDD"
BASE COUNT 946 a 622 c 641 g 933 t
ORIGIN
1 gtggccgctg ccgcctctgc ctgggtccct tcggccgtac ctctgcgtgg gggctgcctc
61 cccggctccc ggtgcagaca ccatgtacgg atttgtgaat cacgccctgg agttgctggt
121 gatccgcaat tacggccccg aggtgtggga agacatcaaa aaagaggcac agttagatga
181 agaaggacag tttcttgtca gaataatata tgatgactcc aaaacttatg atttggttgc
241 tgctgcaagc aaagtcctca atctcaatgc tggagaaatc ctccaaatgt ttgggaagat
301 gtttttcgtc ttttgccaag aatctggtta tgatacaatc ttgcgtgtcc tgggctctaa
361 tgtcagagaa tttctacaga accttgatgc tctgcacgac caccttgcta ccatctaccc
421 aggaatgcgt gcaccttcct ttaggtgcac tgatgcagaa aagggcaaag gactcatttt
481 gcactactac tcagagagag aaggacttca ggatattgtc attggaatca tcaaaacagt
541 ggcacaacaa atccatggca ctgaaataga catgaaggtt attcagcaaa gaaatgaaga
601 atgtgatcat actcaatttt taattgaaga aaaagagtca aaagaagagg atttttatga
661 agatcttgac agatttgaag aaaatggtac ccaggaatca cgcatcagcc catatacatt
721 ctgcaaagct tttccttttc atataatatt tgaccgggac ctagtggtca ctcagtgtgg
781 caatgctata tacagagttc tcccccagct ccagcctggg aattgcagcc ttctgtctgt
841 cttctcgctg gttcgtcctc atattgatat tagtttccat gggatccttt ctcacatcaa
901 tactgttttt gtattgagaa gcaaggaagg attgttggat gtggagaaat tagaatgtga
961 ggatgaactg actgggactg agatcagctg cttacgtctc aagggtcaaa tgatctactt
1021 acctgaagca gatagcatac tttttctatg ttcaccaagt gtcatgaacc tggacgattt
1081 gacaaggaga gggctgtatc taagtgacat ccctctgcat gatgccacac gcgatcttgt
1141 tcttttggga gaacaattta gagaggaata caaactcacc caagaactgg aaatcctcac
1201 tgacaggcta cagctcacgt taagagccct ggaagatgaa aagaaaaaga cagacacatt
1261 gctgtattct gtccttcctc cgtctgttgc caatgagctg cggcacaagc gtccagtgcc
1321 tgccaaaaga tatgacaatg tgaccatcct ctttagtggc attgtgggct tcaatgcttt
1381 ctgtagcaag catgcatctg gagaaggagc catgaagatc gtcaacctcc tcaacgacct
1441 ctacaccaga tttgacacac tgactgattc ccggaaaaac ccatttgttt ataaggtgga
1501 gactgttggt gacaagtata tgacagtgag tggtttacca gagccatgca ttcaccatgc
1561 acgatccatc tgccacctgg ccttggacat gatggaaatt gctggccagg ttcaagtaga
1621 tggtgaatct gttcagataa caatagggat acacactgga gaggtagtta caggtgtcat
1681 aggacagcgg atgcctcgat actgtctttt tgggaatact gtcaacctca caagccgaac
1741 agaaaccaca ggagaaaagg gaaaaataaa tgtgtctgaa tatacataca gatgtcttat
1801 gtctccagaa aattcagatc cacaattcca cttggagcac agaggcccag tgtccatgaa
1861 gggcaaaaaa gaaccaatgc aagtttggtt tctatccaga aaaaatacag gaacagagga
1921 aacaaagcag gatgatgact gaatcttgga ttgtggggtg aagaggagta cagactaggt
1981 tccagttttc tcctaacacg tgccaagccc aggagcagtt cttccctatg gatacagatt
2041 ttcttttgtc cttgtccatt accccaagac tttcttctag atatatctct cactatccgt
2101 tattcaacct tagctctgct ttctattact ttttaggctt tagtatatta tctaaagttt
2161 ggcttttgat gtggatgatg tgagcttcat gtgtcttaaa atctactaca agcattacct
2221 aacatggtga tctgcaagta gtaggcaccc aataaatatt tgttgaattt agttaaatga
2281 aactgaacag tgtttggcca tgtgtatatt tatatcatgt ttaccaaatc tgtttagtgt
2341 tccacatata tgtatatgta tattttaatg actataatgt aataaagttt atatcatgtt
2401 ggtgtatatc attatagaaa tcattttcta aaggagtgaa ttctaagttt taggggaaaa
2461 aatgcaattt attttcagac tcccaaagta agaattaaca tatcatgcta agaaaatagt
2521 gactattttg aagtatgcta cttccctttc agaaatatag aatacacgtt tctgttatta
2581 aagtatttga ttactaattc aaatcatatg gcaattataa ttcttctaaa atgctatcat
2641 ttgtaactgt atcccctgta ttaaatctca ttaaccacag gcagctgtta cagaaagctg
2701 cattgtttca cattgagctg ttacattagt tcaggctaaa tgttgggcgc tccaaccaca
2761 tccaagaata aatctggaaa cacactgctg ggatactgct gttagagccc ttcttggcct
2821 tgtattccca gaaatgagct ccctttcctt agcttagaag aatgtgatta tatccaggac
2881 atcatgttca gaaaacttag tttactttca gcatagaatg cattactgtt ggaataattg
2941 gcctctagct cttaaatgtc tctgataact tattaatatc tatctttata aaatagagtg
3001 caactacttt tgtgtaaaaa tgtttgcctt taaatttagt atttcatatc agcacatcga
3061 tatatgtata aatgttccat gttaatgtgt aaaagagtct gtaataaatt atttttttca
3121 cgtgtcaaaa aaaaaaaaaa aa
//