LOCUS BC047591 2959 bp mRNA linear HUM 30-JUL-2005
DEFINITION Homo sapiens insulin receptor, mRNA (cDNA clone IMAGE:4823710),
partial cds.
ACCESSION BC047591
VERSION BC047591.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2959)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2959)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (03-MAR-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Miklos Palkovits, M.D., Ph.D.
cDNA Library Preparation: Michael J. Brownstein (NHGRI) & Shiraki
Toshiyuki and Piero Carninci (RIKEN)
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 90 Row: g Column: 15.
FEATURES Location/Qualifiers
source 1..2959
/db_xref="H-InvDB:HIT000098680"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:4823710"
/tissue_type="Testis"
/clone_lib="NIH_MGC_97"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene <1..2959
/gene="INSR"
/db_xref="GeneID:3643"
/db_xref="MIM:147670"
CDS <1..2234
/gene="INSR"
/codon_start=3
/product="INSR protein"
/protein_id="AAH47591.1"
/db_xref="GeneID:3643"
/db_xref="MIM:147670"
/translation="AATPLLVAVAALLLGAAGHLYPGEVCPGMDIRNNLTRLHELENC
SVIEGHLQILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRG
SRLFFNYALVIFEMVHLKELGLYNLMNITRGSVRIEKNNELCYLATIDWSRILDSVED
NYIVLNKDDNEECGDICPGTAKGKTNCPATVINGQFVERCWTHSHCQKVCPTICKSHG
CNAEGLCCHSECLGNCSQPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDWRCVNFSL
CQDLHHKCKNSRRQGCHQYVIHNNKCIPECPSGYTMNSSNLLCTPCLGPCPKVCHLLE
GEKTIDSVTSAQELRGCTVINGSLIINIRGGNNLAAELEANLGLIEEISGYLKIRRSY
ALVSLSFFRKLRLIRGETLEIGNYSFYALDNQNLRQLWDWSKHNLTITQGKLFFHYNP
KLCLSEIHKMEEVSGTKGRQERNDIALKTNGDQASCENELLKFSYIRTSFDKILLRWE
PYWPPDFRDLLGFMLFYKEAPYQNVTEFDGQDACGSNSWTVVDIDPPLRSNDPKSQNH
PGWLMRGLKPWTQYAIFVKTLVTFSDERRTYGAKSDIIYVQTDATNPSVPLDPISVSN
SSSQIILKWKPPSDPNGNITHYLVFWERQAEDSELFELDYCLKGLKLPSRTWSPPFES
EDSQKHNQSEYEDSAGECCSCPKTDSQILKELEESSFRKTFEDYLHNVVFVPRSGLGA
GLS"
BASE COUNT 694 a 804 c 779 g 682 t
ORIGIN
1 cggcggccac gccgctgctg gtggcggtgg ccgcgctgct actgggcgcc gcgggccacc
61 tgtaccccgg agaggtgtgt cccggcatgg atatccggaa caacctcact aggttgcatg
121 agctggagaa ttgctctgtc atcgaaggac acttgcagat actcttgatg ttcaaaacga
181 ggcccgaaga tttccgagac ctcagtttcc ccaaactcat catgatcact gattacttgc
241 tgctcttccg ggtctatggg ctcgagagcc tgaaggacct gttccccaac ctcacggtca
301 tccggggatc acgactgttc tttaactacg cgctggtcat cttcgagatg gttcacctca
361 aggaactcgg cctctacaac ctgatgaaca tcacccgggg ttctgtccgc atcgagaaga
421 acaatgagct ctgttacttg gccactatcg actggtcccg tatcctggat tccgtggagg
481 ataattacat cgtgttgaac aaagatgaca acgaggagtg tggagacatc tgtccgggta
541 ccgcgaaggg caagaccaac tgccccgcca ccgtcatcaa cgggcagttt gtcgaacgat
601 gttggactca tagtcactgc cagaaagttt gcccgaccat ctgtaagtca cacggctgca
661 acgccgaagg cctctgttgc cacagcgagt gcctgggcaa ctgttctcag cccgacgacc
721 caaccaagtg cgtggcctgc cgcaacttct acctggacgg caggtgtgtg gagacctgcc
781 cgcccccgta ctaccacttc caggactggc gctgtgtgaa cttcagctta tgccaggacc
841 tgcaccacaa atgcaagaac tcgcggaggc agggctgcca ccagtacgtc attcacaaca
901 acaagtgcat ccctgagtgt ccctccgggt acacgatgaa ttccagcaac ttgctgtgca
961 ccccatgcct gggtccctgt cccaaggtgt gccacctcct agaaggcgag aagaccatcg
1021 actcggtgac gtctgcccag gagctccgag gatgcaccgt catcaacggg agtctgatca
1081 tcaacattcg aggaggcaac aatctggcag ctgagctaga agccaacctc ggcctcattg
1141 aagaaatttc agggtatcta aaaatccgcc gatcctacgc tctggtgtca ctttccttct
1201 tccggaagtt acgtctgatt cgaggagaga ccttggaaat tgggaactac tccttctatg
1261 ccttggacaa ccagaaccta aggcagctct gggactggag caaacacaac ctcaccatca
1321 ctcaggggaa actcttcttc cactataacc ccaaactctg cttgtcagaa atccacaaga
1381 tggaagaagt ttcaggaacc aaggggcgcc aggagagaaa cgacattgcc ctgaagacca
1441 atggggacca ggcatcctgt gaaaatgagt tacttaaatt ttcttacatt cggacatctt
1501 ttgacaagat cttgctgaga tgggagccgt actggccccc cgacttccga gacctcttgg
1561 ggttcatgct gttctacaaa gaggcccctt atcagaatgt gacggagttc gacgggcagg
1621 atgcgtgtgg ttccaacagt tggacggtgg tagacattga cccaccactg aggtccaacg
1681 accccaaatc acagaaccac ccagggtggc tgatgcgggg tctcaagccc tggacccagt
1741 atgccatctt tgtgaagacc ctggtcacct tttcggatga acgccggacc tatggggcca
1801 agagtgacat catttatgtc cagacagatg ccaccaaccc ctctgtgccc ctggatccaa
1861 tctcagtgtc taactcatca tcccagatta ttctgaagtg gaaaccaccc tccgacccca
1921 atggcaacat cacccactac ctggttttct gggagaggca ggcggaagac agtgagctgt
1981 tcgagctgga ttattgcctc aaagggctga agctgccctc gaggacctgg tctccaccat
2041 tcgagtctga agattctcag aagcacaacc agagtgagta tgaggattcg gccggcgaat
2101 gctgctcctg tccaaagaca gactctcaga tcctgaagga gctggaggag tcctcgttta
2161 ggaagacgtt tgaggattac ctgcacaacg tggttttcgt ccccaggtca ggacttggcg
2221 ctgggctctc ttagtgggtg ccaattggct tggtgttggt ggaaggtcat tacttaggga
2281 ccgagaggta gtgggaccca gagacggcag aagggtgggt ggagcctgaa tggagccctt
2341 tcctgggtgg aggaagagat cttgcagttt cgaaatttcg aggggaattt tatcaggaag
2401 agcaaataat cgcacaaaag gggaaaaatg gacaaaactc agcatttgcc tttcttacct
2461 ctcctgagct ggtctccacg tgagttccaa aacaaactcc gttagacgat taacattttt
2521 ttttttctct ctctctcttt tttttttttt tgacagagtc tcactctgtc gtccaggctg
2581 gagtgcggtg gtgcgatttc agctcaccct ttccgggttc gagtgattct tgtgcctcag
2641 cctcccaagt agctgggact acaggtgcgc agcaccacgc ccagctaatt tttatatttt
2701 tagtagagac ggggttttgc catgttggcc aggctggtct ctaacccctg acctcaggtg
2761 atctgcctgc ctcggcctcc cagagtgctg ggattatagg tgtgagccac cgtgcctggc
2821 cgtgattatt gaggctttag ctgagcgcag tggtgtaagc ctgtggtccc agctacttgg
2881 gaagccgagg tggtagggtt gcttgaggcc agcctgggca acataatgag accccatcgc
2941 taccaaaaaa aaaaaaaaa
//