LOCUS BC047559 2567 bp mRNA linear HUM 17-JUL-2007
DEFINITION Homo sapiens RhoA/RAC/CDC42 exchange factor, mRNA (cDNA clone
MGC:44765 IMAGE:5311038), complete cds.
ACCESSION BC047559
VERSION BC047559.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2567)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2567)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (03-MAR-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Miklos Palkovits, M.D., Ph.D.
cDNA Library Preparation: Michael J. Brownstein (NHGRI) & Shiraki
Toshiyuki and Piero Carninci (RIKEN)
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 77 Row: n Column: 12
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 33667114.
FEATURES Location/Qualifiers
source 1..2567
/db_xref="H-InvDB:HIT000053165"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:44765 IMAGE:5311038"
/tissue_type="Brain, hypothalamus"
/clone_lib="NIH_MGC_96"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..2567
/gene="GEFT"
/gene_synonym="p63RhoGEF"
/db_xref="GeneID:115557"
/db_xref="MIM:610215"
CDS 461..2203
/gene="GEFT"
/gene_synonym="p63RhoGEF"
/codon_start=1
/product="RhoA/RAC/CDC42 exchange factor"
/protein_id="AAH47559.1"
/db_xref="GeneID:115557"
/db_xref="MIM:610215"
/translation="MRGGHKGGRCACPRVIRKVLAKCGCCFARGGRESYSIAGSEGSI
SASAASGLAAPSGPSSGLSSGPCSPGPPGPVSGLRRWLDHSKHCLSVETEADSGQAGP
YENWMLEPALATGEELPELTLLTTLLEGPGDKTQPPEEETLSQAPESEEEQKKKALER
SMYVLSELVETEKMYVDDLGQIVEGYMATMAAQGVPESLRGRDRIVFGNIQQIYEWHR
DYFLQELQRCLKDPDWLAQLFIKHERRLHMYVVYYQNKPKSEHVVSEFGDSYFEELRQ
QLGHRLQLNDLLIKPVQRIMKYQLLLKDFLKYYNRAGMDTADLEQAVEVMCFVPKRCN
DMMTLGRLRGFEGKLTAQGKLLGQDTFWVTEPEAGGLLSSRGRERRVFLFEQIIIFSE
ALGGRVRGGTQPGYVYKNSIKVSCLGLEGNLQGDPCRFALTSRGPEGGIQRYVLQAAD
PAISQAWIKHVAQILESQRDFLNALQSPIEYQRRESQTNSLGRPRGPGVGSPGRIRLG
DQAQGSTHTPINGSLPSLLLSPKGEVARALLPLDKQALGDIPQAPHDSPPVSPTPKTP
PCQARLAKLDEDEL"
BASE COUNT 545 a 741 c 768 g 513 t
ORIGIN
1 attcagctct ccgctccgct gggacccgca cagcgccagt ggctcggggg tcggccctcg
61 cctcctcccc ggcccgggcc tagagccacc cctaaccaga ggccggagac agctggagcg
121 gctgccgcat cccggcccag cctcccctac catccctccc ccttccactg gacatctgga
181 ccctaggccc ccgcaccgac agggttccgg aaaccctccc cgcccagccc ggcggccggg
241 ccccgcgcct ctctctctct agagccccca gccctcctca agactagact tccgcctacc
301 cctggacacc tcctcccggt cccctccctc cccccctccc acagcctgga ccggggtagg
361 agggaggggg ggtgtgcgcc cggcgccatc cccgccccgc cccccgtgat tccccctgca
421 tggccggccc gggtgggggg cgcggggggg cccgggcgcc atgcgggggg ggcacaaagg
481 gggtcgctgt gcctgtcccc gtgtgatccg aaaagtgctg gcaaaatgcg gctgctgctt
541 cgcccggggg ggacgtgaat cctattccat tgcgggcagt gaggggagta tatcggcttc
601 tgctgcctcc ggtctggctg ccccctctgg ccccagctct ggcctcagct ctggcccctg
661 ttccccaggc cccccagggc ccgtcagtgg cctgaggaga tggttggatc attccaaaca
721 ttgtctcagt gtggaaactg aggcagacag tggtcaggca ggaccatatg agaactggat
781 gttggagcca gctctagcca caggagagga gctgccggaa ctgaccttgc tgaccacact
841 gttggagggc cctggagata agacgcagcc acctgaagag gagactttgt cccaagcccc
901 tgagagtgag gaggaacaga agaagaaggc tctggaaagg agtatgtatg tcctgagtga
961 actggtagaa acagagaaaa tgtacgtgga cgacttgggg cagattgtgg agggttatat
1021 ggccaccatg gctgctcagg gggtccccga gagtcttcga ggccgtgaca ggattgtgtt
1081 tgggaatatc cagcaaatct atgagtggca ccgagactat ttcttgcaag agctacaacg
1141 gtgtctgaaa gatcctgatt ggctggctca gctattcatc aaacacgagc gccggctgca
1201 tatgtatgtg gtgtactatc agaataagcc caagtcagag catgtggtgt cagagtttgg
1261 ggacagctac tttgaggagc tccggcagca gctggggcac cgcctgcagc tgaacgacct
1321 cctcatcaaa cctgtgcagc ggatcatgaa ataccagctg ctgctcaagg attttctcaa
1381 gtattacaat agagctggga tggatactgc agacctagag caagctgtgg aggtcatgtg
1441 ctttgtgccc aagcgctgca acgatatgat gacgctgggg agattgcggg gatttgaggg
1501 caaactgact gctcagggga agctcttggg ccaggacact ttctgggtca ccgagcctga
1561 ggctggaggg ctgctgtctt cccgaggtcg agagaggcgc gtcttcctct ttgagcaaat
1621 catcatcttc agtgaagccc tgggaggaag agtgagaggt ggaacacagc ctggatatgt
1681 atacaagaac agcattaagg tgagctgcct gggactggag gggaacctcc aaggtgaccc
1741 ttgccgcttt gcactgacct ccagagggcc agagggtggg atccagcgct atgtcctgca
1801 ggctgcagac cctgctatca gtcaggcctg gatcaagcat gtggctcaga tcttggagag
1861 ccaacgggac ttcctcaacg cattgcagtc acccattgag taccagagac gggagagcca
1921 gaccaacagc ctggggcggc caagagggcc tggagtgggg agccctggaa gaattcggct
1981 tggagatcag gcccagggca gcacacacac acccatcaat ggctctctcc cctctctgct
2041 gctgtcaccc aaaggggagg tggccagagc cctcttgcca ctggataaac aggcccttgg
2101 tgacatcccc caggctcccc atgactctcc tccagtctct ccaactccaa aaacccctcc
2161 ctgccaagcc agacttgcca agctggatga agatgagctg taactggtga aaaccatggg
2221 ggtggtgctg actcagccgc ctattcccca aggagcttca gggcagtcct tctggcactg
2281 ctccagaatt cctccttctt ggtgtgtctg gagggtgggc aaggctggga gggatatcaa
2341 cttggaggag aacacctaga cccaaggact tttttctgcc caaggaacac agtttccttc
2401 agctcccatc cctatgcatg catcatggtc cccccaaaag gaggatatgt gggtgggtgg
2461 gagggctggg gcaggggcca gatagaaatt attggttttg ttttttaatt ttgtttttcc
2521 tgttttctga gaataaaggt tttgttataa caaaaaaaaa aaaaaaa
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